In Mexico, the war on drugs was closely tied to US-Mexican relations, with the US exerting significant influence over Mexican drug policy. The Mexican government's efforts to prohibit drugs were often unsuccessful, and the country's drug trade continued to thrive

1940 Reglamento Federal de Toxicomanías in Mexico were key milestones in this process.

For example, in Mexico, the association between the Chinese and opium led to xenophobic attitudes towards drug use.

Mexico, with its own history of demonizing intoxicants and imposing laws to curb their distribution and abuse, was already in compliance with the Hague Convention's mandates and had created domestic laws that were harsher and more far-reaching than what was required by international law.

Marijuana, on the other hand, was thoroughly demonized and eventually prohibited in 1920 as a drug that threatened to "degenerate the race."

dawn of independence in 1821, Mexico already had a long tradition of anti-drug rhetoric and regulatory mechanisms designed to curb "drug abuse." The situation continued to evolve, with the impermanence and flux of modernity inspiring both widespread concern about the harms of intoxicants and widespread use of them.

In Mexico, the creation of pariah drugs was a long-term process that involved various factors, including colonial conflicts, social prejudice, nationalism, economic interests, state-building, geopolitics, transnational intellectual currents, professional interests, and concerns about drug use and abuse.

arbitrary cultural taboo

weed is commonly used among the old Mexican soldiers it is probable that El Paso became infected from that source.

cholars predict that marijuana smuggling from the US to Mexico will continue if Mexico's laws remain stricter than those in the US.

Traditional folk medical practices in Mexico may have also played a role in the demand for marijuana.

The drug's reputation as a "killer weed" was likely influenced by Mexican ideas about marijuana, which associated it with violence, madness, and crime.