DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 38880,RRID:BDSC_38880)

Curator: @scibot

SciCrunch record: RRID:BDSC_38880

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 458,RRID:BDSC_458)

Curator: @scibot

SciCrunch record: RRID:BDSC_458

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 52448,RRID:BDSC_52448)

Curator: @scibot

SciCrunch record: RRID:BDSC_52448

What is this?

DOI: 10.7554/eLife.48264

Resource: RRID:BDSC_52736

Curator: @scibot

SciCrunch record: RRID:BDSC_52736

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 50742,RRID:BDSC_50742)

Curator: @scibot

SciCrunch record: RRID:BDSC_50742

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 30829,RRID:BDSC_30829)

Curator: @scibot

SciCrunch record: RRID:BDSC_30829

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 854,RRID:BDSC_854)

Curator: @scibot

SciCrunch record: RRID:BDSC_854

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 30026,RRID:BDSC_30026)

Curator: @scibot

SciCrunch record: RRID:BDSC_30026

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 7108,RRID:BDSC_7108)

Curator: @scibot

SciCrunch record: RRID:BDSC_7108

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 32216,RRID:BDSC_32216)

Curator: @scibot

SciCrunch record: RRID:BDSC_32216

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 24651,RRID:BDSC_24651)

Curator: @scibot

SciCrunch record: RRID:BDSC_24651

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 27571,RRID:BDSC_27571)

Curator: @scibot

SciCrunch record: RRID:BDSC_27571

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 52869,RRID:BDSC_52869)

Curator: @scibot

SciCrunch record: RRID:BDSC_52869

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 42747,RRID:BDSC_42747)

Curator: @scibot

SciCrunch record: RRID:BDSC_42747

What is this?

DOI: 10.7554/eLife.48264

Resource: (BDSC Cat# 59216,RRID:BDSC_59216)

Curator: @scibot

SciCrunch record: RRID:BDSC_59216

What is this?

DOI: 10.7554/eLife.39611

Resource: Clustal Omega (RRID:SCR_001591)

Curator: @scibot

SciCrunch record: RRID:SCR_001591

What is this?

DOI: 10.7554/eLife.39611

Resource: PDBsum (RRID:SCR_006511)

Curator: @scibot

SciCrunch record: RRID:SCR_006511

What is this?

DOI: 10.7554/eLife.39611

Resource: CCP4 (RRID:SCR_007255)

Curator: @scibot

SciCrunch record: RRID:SCR_007255

What is this?

DOI: 10.7554/eLife.39611

Resource: BUSTER (RRID:SCR_015653)

Curator: @scibot

SciCrunch record: RRID:SCR_015653

What is this?

DOI: 10.7554/eLife.39611

Resource: Phenix (RRID:SCR_014224)

Curator: @scibot

SciCrunch record: RRID:SCR_014224

What is this?

DOI: 10.7554/eLife.39611

Resource: Coot (RRID:SCR_014222)

Curator: @scibot

SciCrunch record: RRID:SCR_014222

What is this?

DOI: 10.7554/eLife.39611

Resource: SHELX (RRID:SCR_014220)

Curator: @scibot

SciCrunch record: RRID:SCR_014220

What is this?

DOI: 10.7554/eLife.39611

Resource: Phaser (RRID:SCR_014219)

Curator: @scibot

SciCrunch record: RRID:SCR_014219

What is this?

DOI: 10.7554/eLife.39611

Resource: XDS Program Package (RRID:SCR_015652)

Curator: @scibot

SciCrunch record: RRID:SCR_015652

What is this?

DOI: 10.7554/eLife.39611

Resource: Phyre (RRID:SCR_010270)

Curator: @scibot

SciCrunch record: RRID:SCR_010270

What is this?

DOI: 10.7554/eLife.39611

Resource: Protein Prospector (RRID:SCR_014558)

Curator: @scibot

SciCrunch record: RRID:SCR_014558

What is this?

DOI: 10.7554/eLife.39611

Resource: PyMOL (RRID:SCR_000305)

Curator: @scibot

SciCrunch record: RRID:SCR_000305

What is this?

DOI: 10.7554/eLife.39611

Resource: ImageQuant (RRID:SCR_014246)

Curator: @scibot

SciCrunch record: RRID:SCR_014246

What is this?

DOI: 10.7554/eLife.27082

Resource: (Abcam Cat# ab19247, RRID:AB_444805)

Curator: @scibot

SciCrunch record: RRID:AB_444805

What is this?

DOI: 10.7554/eLife.27082

Resource: (Santa Cruz Biotechnology Cat# sc-101614, RRID:AB_1129174)

Curator: @scibot

SciCrunch record: RRID:AB_1129174

What is this?

DOI: 10.7554/eLife.79156

Resource: (DSHB Cat# 1E8, RRID:AB_2078498)

Curator: @scibot

SciCrunch record: RRID:AB_2078498

What is this?

DOI: 10.7554/eLife.79156

Resource: (DSHB Cat# mAb 270, RRID:AB_531809)

Curator: @scibot

SciCrunch record: RRID:AB_531809

What is this?

DOI: 10.7554/eLife.79156

Resource: (Millipore Cat# AB152, RRID:AB_390204)

Curator: @bandrow

SciCrunch record: RRID:AB_390204

What is this?

DOI: 10.7554/eLife.79156

Resource: (Millipore Cat# AB5727, RRID:AB_2195375)

Curator: @bandrow

SciCrunch record: RRID:AB_2195375

What is this?

DOI: 10.7554/eLife.89176

Resource: RRID:Addgene_128414

Curator: @scibot

SciCrunch record: RRID:Addgene_128414

What is this?

DOI: 10.7554/eLife.89176

Resource: (Molecular Probes Cat# A-11122, RRID:AB_221569)

Curator: @scibot

SciCrunch record: RRID:AB_221569

What is this?

DOI: 10.7554/eLife.89176

Resource: (Santa Cruz Biotechnology Cat# sc-40, RRID:AB_627268)

Curator: @scibot

SciCrunch record: RRID:AB_627268

What is this?

DOI: 10.7554/eLife.89176

Resource: (Cell Signaling Technology Cat# 3724, RRID:AB_1549585)

Curator: @scibot

SciCrunch record: RRID:AB_1549585

What is this?

DOI: 10.7554/eLife.89176

Resource: (Sigma-Aldrich Cat# A8592, RRID:AB_439702)

Curator: @scibot

SciCrunch record: RRID:AB_439702

What is this?

DOI: 10.7554/eLife.89176

Resource: (Santa Cruz Biotechnology Cat# sc-47724, RRID:AB_627678)

Curator: @scibot

SciCrunch record: RRID:AB_627678

What is this?

DOI: 10.7554/eLife.89176

Resource: (Santa Cruz Biotechnology Cat# sc-508, RRID:AB_628122)

Curator: @scibot

SciCrunch record: RRID:AB_628122

What is this?

DOI: 10.7554/eLife.89176

Resource: (Sigma-Aldrich Cat# A5441, RRID:AB_476744)

Curator: @scibot

SciCrunch record: RRID:AB_476744

What is this?

DOI: 10.7554/eLife.89176

Resource: (R and D Systems Cat# AF467, RRID:AB_355375)

Curator: @scibot

SciCrunch record: RRID:AB_355375

What is this?

DOI: 10.7554/eLife.89176

Resource: (Cell Signaling Technology Cat# 9102, RRID:AB_330744)

Curator: @scibot

SciCrunch record: RRID:AB_330744

What is this?

DOI: 10.7554/eLife.89176

Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)

Curator: @scibot

SciCrunch record: RRID:AB_331646

What is this?

DOI: 10.7554/eLife.89176

Resource: (Abcam Cat# ab86078, RRID:AB_1925230)

Curator: @scibot

SciCrunch record: RRID:AB_1925230

What is this?

DOI: 10.7554/eLife.90799.2

Resource: (Synaptic Systems Cat# 135 302, RRID:AB_887877)

Curator: @scibot

SciCrunch record: RRID:AB_887877

What is this?

DOI: 10.7554/eLife.90799.2

Resource: (Jackson ImmunoResearch Labs Cat# 115-005-207, RRID:AB_2338463)

Curator: @scibot

SciCrunch record: RRID:AB_2338463

What is this?

DOI: 10.7554/eLife.90799.2

Resource: (Jackson ImmunoResearch Labs Cat# 711-005-152, RRID:AB_2340585)

Curator: @scibot

SciCrunch record: RRID:AB_2340585

What is this?

DOI: 10.7554/eLife.90799.2

Resource: (Jackson ImmunoResearch Labs Cat# 115-005-205, RRID:AB_2338461)

Curator: @scibot

SciCrunch record: RRID:AB_2338461

What is this?

DOI: 10.7554/eLife.90799.2

Resource: (Jackson ImmunoResearch Labs Cat# 115-005-206, RRID:AB_2338462)

Curator: @scibot

SciCrunch record: RRID:AB_2338462

What is this?

DOI: 10.7554/eLife.90799.2

Resource: (Jackson ImmunoResearch Labs Cat# 706-475-148, RRID:AB_2340470)

Curator: @scibot

SciCrunch record: RRID:AB_2340470

What is this?

DOI: 10.7554/eLife.90799.2

Resource: (Synaptic Systems Cat# 152 311, RRID:AB_2619843)

Curator: @scibot

SciCrunch record: RRID:AB_2619843

What is this?

DOI: 10.7554/eLife.90799.2

Resource: (Synaptic Systems Cat# 152 203, RRID:AB_2619841)

Curator: @scibot

SciCrunch record: RRID:AB_2619841

What is this?

DOI: 10.7554/eLife.90799.2

Resource: (UC Davis/NIH NeuroMab Facility Cat# K28/43, RRID:AB_2877189)

Curator: @scibot

SciCrunch record: RRID:AB_2877189

What is this?

DOI: 10.7554/eLife.90799.2

Resource: (Synaptic Systems Cat# 135 304, RRID:AB_887878)

Curator: @scibot

SciCrunch record: RRID:AB_887878

What is this?

DOI: 10.7554/eLife.88328

Resource: (DGRC Cat# 150, RRID:CVCL_Z831)

Curator: @scibot

SciCrunch record: RRID:CVCL_Z831

What is this?

DOI: 10.7554/eLife.88328

Resource: R Project for Statistical Computing (RRID:SCR_001905)

Curator: @scibot

SciCrunch record: RRID:SCR_001905

What is this?

DOI: 10.7554/eLife.88328

Resource: Python Programming Language (RRID:SCR_008394)

Curator: @scibot

SciCrunch record: RRID:SCR_008394

What is this?

DOI: 10.7554/eLife.88328

Resource: REViGO (RRID:SCR_005825)

Curator: @scibot

SciCrunch record: RRID:SCR_005825

What is this?

DOI: 10.7554/eLife.88406

Resource: (IMSR Cat# JAX_000664,RRID:IMSR_JAX:000664)

Curator: @scibot

SciCrunch record: RRID:IMSR_JAX:000664

What is this?

DOI: 10.7554/eLife.86663

Resource: AB_1968650

Curator: @scibot

SciCrunch record: RRID:AB_1968650

What is this?

DOI: 10.7554/eLife.86663

Resource: (Roche Cat# 11815016001, RRID:AB_390914)

Curator: @scibot

SciCrunch record: RRID:AB_390914

What is this?

DOI: 10.7554/eLife.86663

Resource: (DSHB Cat# Drosophila Ptc (Apa 1), RRID:AB_528441)

Curator: @scibot

SciCrunch record: RRID:AB_528441

What is this?

DOI: 10.7554/eLife.86663

Resource: (DSHB Cat# 4d4, RRID:AB_528512)

Curator: @scibot

SciCrunch record: RRID:AB_528512

What is this?

DOI: 10.7554/eLife.92915.1

Resource: Vermont University Larner College of Medicine Microscopy Imaging Center Core Facility (RRID:SCR_018821)

Curator: @scibot

SciCrunch record: RRID:SCR_018821

What is this?

DOI: 10.7554/eLife.92915.1

Resource: SPSS (RRID:SCR_002865)

Curator: @scibot

SciCrunch record: RRID:SCR_002865

What is this?

DOI: 10.7554/eLife.92915.1

Resource: GraphPad Prism (RRID:SCR_002798)

Curator: @scibot

SciCrunch record: RRID:SCR_002798

What is this?

DOI: 10.7554/eLife.92915.1

Resource: Axograph (RRID:SCR_014284)

Curator: @scibot

SciCrunch record: RRID:SCR_014284

What is this?

DOI: 10.7554/eLife.92915.1

Resource: pClamp (RRID:SCR_011323)

Curator: @scibot

SciCrunch record: RRID:SCR_011323

What is this?

DOI: 10.7554/eLife.88579

Resource: ImageJ (RRID:SCR_003070)

Curator: @scibot

SciCrunch record: RRID:SCR_003070

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 65419,RRID:BDSC_65419)

Curator: @Naa003

SciCrunch record: RRID:BDSC_65419

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 30037,RRID:BDSC_30037)

Curator: @Naa003

SciCrunch record: RRID:BDSC_30037

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 5072,RRID:BDSC_5072)

Curator: @Naa003

SciCrunch record: RRID:BDSC_5072

What is this?

DOI: 10.7554/eLife.41036

Resource: BDSC_42523

Curator: @Naa003

SciCrunch record: RRID:BDSC_42523

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 60731,RRID:BDSC_60731)

Curator: @Naa003

SciCrunch record: RRID:BDSC_60731

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 56562,RRID:BDSC_56562)

Curator: @Naa003

SciCrunch record: RRID:BDSC_56562

What is this?

DOI: 10.7554/eLife.41036

Resource: RRID:BDSC_4777

Curator: @Naa003

SciCrunch record: RRID:BDSC_4777

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 35371,RRID:BDSC_35371)

Curator: @Naa003

SciCrunch record: RRID:BDSC_35371

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 62155,RRID:BDSC_62155)

Curator: @Naa003

SciCrunch record: RRID:BDSC_62155

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 9306,RRID:BDSC_9306)

Curator: @Naa003

SciCrunch record: RRID:BDSC_9306

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 1521,RRID:BDSC_1521)

Curator: @Naa003

SciCrunch record: RRID:BDSC_1521

What is this?

DOI: 10.7554/eLife.41036

Resource: BDSC_36117

Curator: @Naa003

SciCrunch record: RRID:BDSC_36117

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 6409,RRID:BDSC_6409)

Curator: @Naa003

SciCrunch record: RRID:BDSC_6409

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 50879,RRID:BDSC_50879)

Curator: @Naa003

SciCrunch record: RRID:BDSC_50879

What is this?

DOI: 10.7554/eLife.41036

Resource: RRID:BDSC_61654

Curator: @Naa003

SciCrunch record: RRID:BDSC_61654

What is this?

DOI: 10.7554/eLife.41036

Resource: RRID:BDSC_8142

Curator: @Naa003

SciCrunch record: RRID:BDSC_8142

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 11173,RRID:BDSC_11173)

Curator: @Naa003

SciCrunch record: RRID:BDSC_11173

What is this?

DOI: 10.7554/eLife.41036

Resource: RRID:BDSC_4169

Curator: @Naa003

SciCrunch record: RRID:BDSC_4169

What is this?

DOI: 10.7554/eLife.41036

Resource: BDSC_65331

Curator: @Naa003

SciCrunch record: RRID:BDSC_65331

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 6761,RRID:BDSC_6761)

Curator: @Naa003

SciCrunch record: RRID:BDSC_6761

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 28282,RRID:BDSC_28282)

Curator: @Naa003

SciCrunch record: RRID:BDSC_28282

What is this?

DOI: 10.7554/eLife.41036

Resource: (BDSC Cat# 44251,RRID:BDSC_44251)

Curator: @Naa003

SciCrunch record: RRID:BDSC_44251

What is this?

DOI: 10.7554/eLife.41036

Resource: DGGR_111872

Curator: @Naa003

SciCrunch record: RRID:DGGR_111872

What is this?

DOI: 10.7554/eLife.41036

Resource: BDSC_42734

Curator: @Naa003

SciCrunch record: RRID:BDSC_42734

What is this?

DOI: 10.7554/eLife.55793

Resource: (BDSC Cat# 25710,RRID:BDSC_25710)

Curator: @Naa003

SciCrunch record: RRID:BDSC_25710

What is this?

DOI: 10.7554/eLife.55793

Resource: (BDSC Cat# 78782,RRID:BDSC_78782)

Curator: @Naa003

SciCrunch record: RRID:BDSC_78782

What is this?

DOI: 10.7554/eLife.55793

Resource: (BDSC Cat# 51324,RRID:BDSC_51324)

Curator: @Naa003

SciCrunch record: RRID:BDSC_51324

What is this?

DOI: 10.7554/eLife.55793

Resource: (BDSC Cat# 78781,RRID:BDSC_78781)

Curator: @Naa003

SciCrunch record: RRID:BDSC_78781

What is this?

DOI: 10.7554/eLife.55793

Resource: (BDSC Cat# 25709,RRID:BDSC_25709)

Curator: @Naa003

SciCrunch record: RRID:BDSC_25709

What is this?

DOI: 10.7554/eLife.55793

Resource: RRID:Addgene_46294

Curator: @scibot

SciCrunch record: RRID:Addgene_46294

What is this?

DOI: 10.7554/eLife.85096

Resource: Thermo Orbitrap Eclipse nanoLC/MS system (RRID:SCR_022212)

Curator: @anisehay

SciCrunch record: RRID:SCR_022212

What is this?

DOI: 10.7554/eLife.87607

Resource: Picard (RRID:SCR_006525)

Curator: @scibot

SciCrunch record: RRID:SCR_006525

What is this?

DOI: 10.7554/eLife.91120

Resource: GraphPad Prism (RRID:SCR_002798)

Curator: @scibot

SciCrunch record: RRID:SCR_002798

What is this?

DOI: 10.7554/eLife.90184

Resource: (Thermo Fisher Scientific Cat# A32728TR, RRID:AB_2866490)

Curator: @scibot

SciCrunch record: RRID:AB_2866490

What is this?

DOI: 10.7554/eLife.90184

Resource: (Thermo Fisher Scientific Cat# A32773, RRID:AB_2762848)

Curator: @scibot

SciCrunch record: RRID:AB_2762848

What is this?

DOI: 10.7554/eLife.90184

Resource: (Thermo Fisher Scientific Cat# A-21206, RRID:AB_2535792)

Curator: @scibot

SciCrunch record: RRID:AB_2535792

What is this?

DOI: 10.7554/eLife.88250

Resource: (Covance Cat# PRB-435P-100, RRID:AB_291637)

Curator: @scibot

SciCrunch record: RRID:AB_291637

What is this?

DOI: 10.7554/eLife.88250

Resource: (Abcam Cat# ab178850, RRID:AB_2721842)

Curator: @scibot

SciCrunch record: RRID:AB_2721842

What is this?

DOI: 10.7554/eLife.88250

Resource: (Molecular Probes Cat# A-11122, RRID:AB_221569)

Curator: @scibot

SciCrunch record: RRID:AB_221569

What is this?

DOI: 10.7554/eLife.88250

Resource: (Abcam Cat# ab6673, RRID:AB_305643)

Curator: @scibot

SciCrunch record: RRID:AB_305643

What is this?

DOI: 10.7554/eLife.88250

Resource: (Millipore Cat# AB144P, RRID:AB_2079751)

Curator: @scibot

SciCrunch record: RRID:AB_2079751

What is this?

DOI: 10.7554/eLife.88250

Resource: (Bio X Cell Cat# BE0102, RRID:AB_10950158)

Curator: @scibot

SciCrunch record: RRID:AB_10950158

What is this?

DOI: 10.7554/eLife.88250

Resource: MGI:2181028

Curator: @scibot

SciCrunch record: RRID:MGI:2181028

What is this?

DOI: 10.7554/eLife.88250

Resource: CVCL_RB07

Curator: @scibot

SciCrunch record: RRID:CVCL_RB07

What is this?

DOI: 10.7554/eLife.90298

Resource: (Abcam Cat# ab9377, RRID:AB_307222)

Curator: @anisehay

SciCrunch record: RRID:AB_307222

What is this?

DOI: 10.7554/eLife.90298

Resource: (Abcam Cat# ab223582, RRID:AB_2762366)

Curator: @anisehay

SciCrunch record: RRID:AB_2762366

What is this?

DOI: 10.7554/eLife.79169

Resource: (Thermo Fisher Scientific Cat# A-11042, RRID:AB_2534099)

Curator: @scibot

SciCrunch record: RRID:AB_2534099

What is this?

DOI: 10.7554/eLife.79169

Resource: (Thermo Fisher Scientific Cat# A-11029, RRID:AB_2534088)

Curator: @scibot

SciCrunch record: RRID:AB_2534088

What is this?

DOI: 10.7554/eLife.79169

Resource: (Millipore Cat# MAB377, RRID:AB_2298772)

Curator: @scibot

SciCrunch record: RRID:AB_2298772

What is this?

DOI: 10.7554/eLife.79169

Resource: (Abcam Cat# ab134458, RRID:AB_2860025)

Curator: @scibot

SciCrunch record: RRID:AB_2860025

What is this?

DOI: 10.7554/eLife.79169

Resource: (Millipore Cat# MAB384-1ML, RRID:AB_240837)

Curator: @scibot

SciCrunch record: RRID:AB_240837

What is this?

通过测定一系列与Aβ产生有关的蛋白和合成过程蛋白（APP C端片段C83和C99、负责APP加工的分泌酶(BACE1, ADAM10和γ-分泌酶PSEN1的催化亚基)的蛋白水平、体外细胞添加SCFA后的γ分泌酶活性），确定SCFA不改变Aβ生成，因此推断改变的是沉积和清除过程。

DOI: 10.7554/eLife.80100

Resource: (MMRRC Cat# 036778-UCD,RRID:MMRRC_036778-UCD)

Curator: @bandrow

SciCrunch record: RRID:MMRRC_036778-UCD

What is this?

DOI: 10.7554/eLife.38752

Resource: ImageJ (RRID:SCR_003070)

Curator: @scibot

SciCrunch record: RRID:SCR_003070

What is this?

DOI: 10.7554/eLife.38752

Resource: Adobe Photoshop (RRID:SCR_014199)

Curator: @scibot

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?

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What is this?