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    Nuclear translocation of SIRT4 mediates deacetylation of U2AF2 to modulate renal fibrosis through alternative splicing-mediated upregulation of CCN2
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    Structure of the TXNL1-bound proteasome
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    Porcine NLRC3 specially binds short dsDNA to regulate cGAS activation
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    Hope for Others: Research Results from the University of Pittsburgh Rapid Autopsy Program for Breast Cancer
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    SUMOylation of protein phosphatase 5 regulates phosphatase activity and substrate release
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    Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
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    wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html
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    Systematic screens for fertility genes essential for malaria parasite transmission reveal conserved aspects of sex in a divergent eukaryote
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    Constitutive and Conditional Epitope Tagging of Endogenous G-Protein–Coupled Receptors in Drosophila
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    Chemogenetic activation of RFRP neurons reduces LH pulse frequency in female but not male mice
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    MYC is Sufficient to Generate Mid-Life High-Grade Serous Ovarian and Uterine Serous Carcinomas in a p53-R270H Mouse Model
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    CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny
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    Highlights from MBoC Selection: Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage
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    Global isonicotinylome analysis identified SMAD3 isonicotinylation promotes liver cancer cell epithelial–mesenchymal transition and invasion
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    Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity
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    Human Labor Pain Is Influenced by the Voltage-Gated Potassium Channel KV6.4 Subunit
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    Protein UFMylation regulates early events during ribosomal DNA-damage response
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    ESR1 Fusions Invoke Breast Cancer Subtype-Dependent Enrichment of Ligand-Independent Oncogenic Signatures and Phenotypes
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    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
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    TGF-β and RAS jointly unmask primed enhancers to drive metastasis
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    Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma
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    E3 ubiquitin ligase ANKIB1 attenuates antiviral immune responses by promoting K48-linked polyubiquitination of MAVS
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    Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression
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    Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS
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    Molecular and circuit determinants in the globus pallidus mediating control of cocaine-induced behavioral plasticity
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    An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation
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    Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer
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    Protocol for establishing inducible CRISPRd system for blocking transcription factor-binding sites in human pluripotent stem cells
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    A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development
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    Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
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    The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response
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    Antisense oligonucleotides enhance SLC20A2 expression and suppress brain calcification in a humanized mouse model
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    Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease
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    Dopaminylation of endothelial TPI1 suppresses ferroptotic angiocrine signals to promote lung regeneration over fibrosis
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    Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
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    Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases
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    RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia
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    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
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    ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis
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    Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma
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    Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate
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    Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway
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    Oligodendrocyte-derived LGI3 and its receptor ADAM23 organize juxtaparanodal Kv1 channel clustering for short-term synaptic plasticity
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    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
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    A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope
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    Design and Characterization of a Novel eEF2K Degrader with Potent Therapeutic Efficacy Against Triple-Negative Breast Cancer
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    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
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    ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors
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    NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance
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    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
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    ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation
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    Eclosion muscles secrete ecdysteroids to initiate asymmetric intestinal stem cell division in Drosophila
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    BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development
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    Yeast lunapark regulates the formation of trans-Sey1p complexes for homotypic ER membrane fusion
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    Stabilizing vimentin phosphorylation inhibits stem-like cell properties and metastasis of hybrid epithelial/mesenchymal carcinomas
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    Preclinical Long-Term Safety of Intraspinal Transplantation of Human Dorsal Spinal GABA Neural Progenitor Cells
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    TET2 is recruited by CREB to promote Cebpb, Cebpa and Pparg transcription by facilitating hydroxymethylation during adipocyte differentiation
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    ATM-CHK2-TRIM32 axis regulates ATG7 ubiquitination to initiate autophagy under oxidative stress
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma
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