591 Matching Annotations
  1. Nov 2024
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Targeting ATAD3A Phosphorylation Mediated by TBK1 Ameliorates Senescence-Associated Pathologies
    1
    1. scibot 15 Nov 2024
      RRID:AB_2070042

      DOI: 10.1002/advs.202404109

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    onlinelibrary.wiley.com/doi/full/10.1002/advs.202404109
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
    1
    1. scibot 08 Nov 2024
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      DOI: 10.1158/0008-5472.CAN-23-3574

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    pmc.ncbi.nlm.nih.gov/articles/PMC11532783/
  4. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    The in vivo effects of knockdown of long non-coding RNA XIST on fibroid growth and gene expression
    1
    1. scibot 07 Nov 2024
      RRID:AB_2070042

      DOI: 10.1096/fj.202401982R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202401982R
  5. Oct 2024
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exploring the reduction in aquaporin-4 and increased expression of ciliary neurotrophic factor with the frontal–striatal gliosis induced by chronic high-fat dietary stress
    1
    1. scibot 08 Oct 2024
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      DOI: 10.1111/jnc.16236

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16236
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Minocycline Administration Does Not Have an Effect on Retinal Ganglion Cell Survival in a Murine Model of Ocular Hypertension
    1
    1. scibot 02 Oct 2024
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      DOI: 10.14336/AD.2024.0224

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    ncbi.nlm.nih.gov/pmc/articles/PMC11346395/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application
    1
    1. scibot 02 Oct 2024
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      DOI: 10.1038/s41467-024-52110-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11427689/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The emerging role of mesenchymal stem cell–derived extracellular vesicles to ameliorate hippocampal NLRP3 inflammation induced by binge-like ethanol treatment in adolescence
    1
    1. scibot 02 Oct 2024
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      DOI: 10.4103/NRR.NRR-D-23-01397

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    ncbi.nlm.nih.gov/pmc/articles/PMC11438346/
  10. Sep 2024
  11. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Sodium butyrate prevents cytokine-induced β-cell dysfunction through restoration of stromal interaction molecule 1 expression and activation of store-operated calcium entry
    1
    1. scibot 27 Sep 2024
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      DOI: 10.1096/fj.202302501RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202302501RR
  12. www.pnas.org www.pnas.org
    MDGAs perform activity-dependent synapse type-specific suppression via distinct extracellular mechanisms
    1
    1. scibot 26 Sep 2024
      RRID:AB_2070042

      DOI: 10.1073/pnas.2322978121

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    pnas.org/doi/10.1073/pnas.2322978121
  13. www.sciencedirect.com www.sciencedirect.com
    Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression
    1
    1. scibot 25 Sep 2024
      RRID:AB_10891784

      DOI: 10.1016/j.celrep.2020.108522

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    sciencedirect.com/science/article/pii/S2211124720315114
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppressor of fused controls perinatal expansion and quiescence of future dentate adult neural stem cells
    1
    1. scibot 25 Sep 2024
      RRID:AB_2070042

      DOI: 10.7554/eLife.42918

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    ncbi.nlm.nih.gov/pmc/articles/PMC6459675/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cannabinoid combination targets NOTCH1-mutated T-cell acute lymphoblastic leukemia through the integrated stress response pathway
    1
    1. scibot 18 Sep 2024
      RRID:AB_2070042

      DOI: 10.7554/eLife.90854

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    ncbi.nlm.nih.gov/pmc/articles/PMC11390110/
  16. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    1. scibot 15 Sep 2024
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      DOI: 10.1002/1878-0261.13725

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13725
  17. www.sciencedirect.com www.sciencedirect.com
    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
    1
    1. scibot 11 Sep 2024
      RRID:AB_2070042

      DOI: 10.1016/j.celrep.2024.114728

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    sciencedirect.com/science/article/pii/S2211124724010799
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting AKR1B10 by drug repurposing with epalrestat overcomes chemoresistance in non-small cell lung cancer patient-derived tumor organoids
    1
    1. scibot 05 Sep 2024
      RRID:AB_2070042

      DOI: 10.1158/1078-0432.CCR-23-3980

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    ncbi.nlm.nih.gov/pmc/articles/PMC11369614/
  19. www.sciencedirect.com www.sciencedirect.com
    Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation
    1
    1. scibot 04 Sep 2024
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      DOI: 10.1016/j.xcrm.2024.101711

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    sciencedirect.com/science/article/pii/S2666379124004324
  20. Aug 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potential of GSPT1 as a novel target for glioblastoma therapy
    1
    1. scibot 21 Aug 2024
      RRID:AB_2070042

      DOI: 10.1038/s41419-024-06967-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11310507/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy
    1
    1. scibot 21 Aug 2024
      RRID:AB_2070042

      DOI: 10.1158/2767-9764.CRC-24-0077

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    ncbi.nlm.nih.gov/pmc/articles/PMC11310748/
  23. www.sciencedirect.com www.sciencedirect.com
    Multiplex Spatial Omics Reveals Changes in Immune-Epithelial Crosstalk During Inflammation and Dysplasia Development in Chronic IBD Patients
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.isci.2024.110550

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    sciencedirect.com/science/article/pii/S2589004224017759
  24. www.sciencedirect.com www.sciencedirect.com
    Thyroid hormone suppresses medulloblastoma progression through promoting terminal differentiation of tumor cells
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.ccell.2024.07.008

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    sciencedirect.com/science/article/pii/S1535610824002733
  25. www.mdpi.com www.mdpi.com
    DYRK1A Overexpression in Mice Downregulates the Gonadotropic Axis and Disturbs Early Stages of Spermatogenesis
    1
    1. scibot 02 Aug 2024
      9664

      DOI: 10.3390/genes12111800

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    mdpi.com/2073-4425/12/11/1800/htm
  26. josr-online.biomedcentral.com josr-online.biomedcentral.com
    Overexpression of FGF2 delays the progression of osteonecrosis of the femoral head activating the PI3K/Akt signaling pathway
    1
    1. scibot 02 Aug 2024
      9664

      DOI: 10.1186/s13018-021-02715-9

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    josr-online.biomedcentral.com/articles/10.1186/s13018-021-02715-9
  27. www.embopress.org www.embopress.org
    HOIP limits anti-tumor immunity by protecting against combined TNF and IFN-gamma-induced apoptosis
    1
    1. scibot 02 Aug 2024
      9664

      DOI: 10.15252/embr.202153391

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    embopress.org/doi/full/10.15252/embr.202153391
  28. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma
    1
    1. scibot 02 Aug 2024
      9664

      DOI: 10.1186/s13578-021-00640-2

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    cellandbioscience.biomedcentral.com/article/10.1186/s13578-021-00640-2
  29. Jul 2024
  30. 52.53.155.43 52.53.155.43
    Minocycline Administration Does Not Have an Effect on Retinal Ganglion Cell Survival in a Murine Model of Ocular Hypertension (1)-html.html
    4
    1. scibot 30 Jul 2024
      RRID:AB_2070042

      DOI: 10.14336/ad.2024.0224

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    2. scibot 26 Jul 2024
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      DOI: 10.14336/ad.2024.0224

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    3. scibot 25 Jul 2024
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      DOI: 10.14336/ad.2024.0224

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    4. scibot 19 Jul 2024
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      DOI: 10.14336/ad.2024.0224

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    52.53.155.43/ad07418c6cc3e7746b7551fa5ba2c2d910d3e6c1/Minocycline Administration Does Not Have an Effect on Retinal Ganglion Cell Survival in a Murine Model of Ocular Hypertension (5)-html.html
  31. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.ccell.2024.06.012

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    sciencedirect.com/science/article/pii/S153561082400237X
  32. www.sciencedirect.com www.sciencedirect.com
    Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101658

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    sciencedirect.com/science/article/pii/S2666379124003720
  33. www.sciencedirect.com www.sciencedirect.com
    Analyzing embryo dormancy at single-cell resolution reveals dynamic transcriptional responses and activation of integrin-Yap/Taz prosurvival signaling
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.stem.2024.06.015

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    sciencedirect.com/science/article/pii/S1934590924002509
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.isci.2024.109912

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    ncbi.nlm.nih.gov/pmc/articles/PMC11225835/
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhalation of hydrogen gas mitigates sevoflurane-induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1111/jnc.16142

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.16142
  36. www.cell.com www.cell.com
    Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.neuron.2024.05.023

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    cell.com/neuron/abstract/S0896-6273(24)00370-2
  37. www.cell.com www.cell.com
    Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.ccell.2024.06.001

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    cell.com/cancer-cell/fulltext/S1535-6108(24)00226-5
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila
    1
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      DOI: 10.1186/s40478-020-01028-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC7487709/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins
    1
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      DOI: 10.4103/NRR.NRR-D-23-00928

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    ncbi.nlm.nih.gov/pmc/articles/PMC11246146/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation
    1
    1. scibot 11 Jul 2024
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      DOI: 10.1016/j.neuron.2019.09.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC6895427/
  41. www.biorxiv.org www.biorxiv.org
    Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor
    1
    1. scibot 04 Jul 2024
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      DOI: 10.1101/2024.06.11.598518

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    biorxiv.org/content/10.1101/2024.06.11.598518v2
  42. Jun 2024
  43. www.sciencedirect.com www.sciencedirect.com
    Monomethyl fumarate attenuates lung Ischemia/Reperfusion injury by disrupting the GAPDH/Siah1 signaling cascade
    1
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    RORψt+CD4+ T cells promote IL-23R-mediated neuronal cell apoptosis in the central nervous system
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  168. May 2023
  169. www.embopress.org www.embopress.org
    Phospholipid scramblase Xkr8 is required for developmental axon pruning via phosphatidylserine exposure
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  170. www.sciencedirect.com www.sciencedirect.com
    VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection
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  171. 52.53.155.43 52.53.155.43
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  172. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin
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    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma
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  175. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Diversity within olfactory sensory derivatives revealed by the contribution of Dbx1 lineages
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  176. Apr 2023
  177. www.sciencedirect.com www.sciencedirect.com
    Alphavirus infection triggers antiviral RNAi immunity in mammals
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    Semi-Supervised Analysis of myeloid and T cell behaviour in ex vivo ovarian tumour slices reveals changes in cell motility after treatments
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    Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons
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    Beclin-1-dependent autophagy, but not apoptosis, is critical for stem-cell-mediated endometrial programming and the establishment of pregnancy
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    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor microenvironment mimicking 3D models unveil the multifaceted effects of SMAC mimetics
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    Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen
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  184. Mar 2023
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis
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    Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes
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  187. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout
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  188. 52.53.155.43 52.53.155.43
    Generation and expansion of transitional lung organoids from human pluripotent stem cells
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    Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2
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    Injury primes mutation-bearing astrocytes for dedifferentiation in later life
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    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
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    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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    Stress Granules determine the Development of Obesity-associated Pancreatic Cancer
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  196. onlinelibrary.wiley.com onlinelibrary.wiley.com
    AMP-activated protein kinase inhibition in fibro-adipogenic progenitors impairs muscle regeneration and increases fibrosis
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    Endoplasmic reticulum associated degradation is essential for maintaining the viability or function of mature myelinating cells in adults
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  199. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In vitro characterization on the role of APOE polymorphism in human hippocampal neurogenesis
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    Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis
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  202. 52.53.155.43 52.53.155.43
    Global cancer statistics, 2012
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  203. 52.53.155.43 52.53.155.43
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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel B7-H6–Targeted IgG-Like T Cell–Engaging Antibody for the Treatment of Gastrointestinal Tumors
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  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
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