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    Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice
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    Carcinoma-associated mesenchymal stem cells promote ovarian cancer heterogeneity and metastasis through mitochondrial transfer
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    β-Hydroxybutyrate Improves the Redox Status, Cytokine Production and Phagocytic Potency of Glucose-Deprived HMC3 Human Microglia-like Cells
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  5. Jul 2024
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    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC7262597/
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    Enteric glial cell network function is required for epithelial barrier restitution following intestinal ischemic injury in the early postnatal period
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    ncbi.nlm.nih.gov/pmc/articles/PMC11211042/
  9. Jun 2024
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    The browning and mobilization of subcutaneous white adipose tissue supports efficient skin repair
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  11. May 2024
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    Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations
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    biorxiv.org/content/10.1101/2024.05.07.592993v1
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    Cav3.2 channel regulates cerebral ischemia/reperfusion injury: a promising target for intervention
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    Hippocampal excitation-inhibition balance underlies the 5-HT2C receptor in modulating depressive behaviours
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    ARID1B controls transcriptional programs of axon projection in an organoid model of the human corpus callosum
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    Identification of a chromatin-bound ERRα interactome network in mouse liver
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  18. Apr 2024
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    Dominant role for pigment epithelial CRALBP in supplying visual chromophore to photoreceptors
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    Hypomethylation-associated LINC00987 downregulation induced lung adenocarcinoma progression by inhibiting the phosphorylation-mediated degradation of SND1
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  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a chromatin-bound ERRα interactome network in mouse liver
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    Comprehensive mutagenesis maps the effect of all single-codon mutations in the AAV2 rep gene on AAV production
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  23. Mar 2024
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    Pten regulates endocytic trafficking of cell adhesion and Wnt signaling molecules to pattern the retina
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    sciencedirect.com/science/article/pii/S2211124724003334
  25. Feb 2024
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    IL-37 dampens immunosuppressive functions of MDSCs via metabolic reprogramming in the tumor microenvironment
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    Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche
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    GLP-1(7–36) protected against oxidative damage and neuronal apoptosis in the hippocampal CA region after traumatic brain injury by regulating ERK5/CREB
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    GRIM19 deficiency aggravates metabolic disorder and ovarian dysfunction in PCOS
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    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EP300 restores glycolytic activity and anti-tumor function of CD8+ cytotoxic T cells in nasopharyngeal carcinoma
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    Circ-CIMIRC inhibition alleviates CIH-induced myocardial damage via FbxL4-mediated ubiquitination of PINK1
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    OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma
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    Combined effect of Cerium oxide nanoparticles loaded scaffold and photobiomodulation therapy on pain and neuronal regeneration following spinal cord injury: an experimental study
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    Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
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    Extracellular Vesicles Derived from Glioma Stem Cells Affect Glycometabolic Reprogramming of Glioma Cells Through the miR-10b-5p/PTEN/PI3K/Akt Pathway
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    Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling
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  38. Jan 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing
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    Single-molecule imaging of stochastic interactions that drive dynein activation and cargo movement in cells
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      DOI: 10.1083/jcb.202210026

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    ncbi.nlm.nih.gov/pmc/articles/PMC10798859/
  41. www-sciencedirect-com.proxy.uchicago.edu www-sciencedirect-com.proxy.uchicago.edu
    Cell surface RNAs control neutrophil recruitment
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    www-sciencedirect-com.proxy.uchicago.edu/science/article/pii/S0092867423014435
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    MIF modulates p38/ERK phosphorylation via MKP-1 induction in sarcoidosis
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    sciencedirect.com/science/article/pii/S2589004223028237
  43. Dec 2023
  44. www.sciencedirect.com www.sciencedirect.com
    The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation
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    In vivo identification of astrocyte and neuron subproteomes by proximity-dependent biotinylation
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      DOI: 10.1038/s41596-023-00923-7

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  46. Nov 2023
  47. dx.doi.org dx.doi.org
    Coexistence of apoptosis, pyroptosis, and necroptosis pathways in Celiac Disease
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      DOI: 10.1093/cei/uxad082

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    TGFB1 induces fetal reprogramming and enhances intestinal regeneration
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    Treatment with β-sitosterol ameliorates the effects of cerebral ischemia/reperfusion injury by suppressing cholesterol overload, endoplasmic reticulum stress, and apoptosis
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    Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease
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  53. Sep 2023
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    Methyltransferase-like 3 facilitates the stem cell properties of esophageal cancer by upregulating patched homolog 1 via N6-methyladenosine methylation
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    Characterization of an in vitro steatosis model simulating activated de novo lipogenesis in MAFLD patients
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    Loss-of-function variants in KCTD19 cause non-obstructive azoospermia in humans
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    LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer
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    Identification of host regulators of Mycobacterium tuberculosis phenotypes uncovers a role for the MMGT1-GPR156 lipid droplet axis in persistence
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    DNA Methylation-Mediated Mfn2 Gene Regulation in the Brain: A Role in Brain Trauma-Induced Mitochondrial Dysfunction and Memory Deficits
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    Mechanical pressure-induced dedifferentiation of myofibroblasts inhibits scarring via SMYD3/ITGBL1 signaling
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    Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia
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    A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer
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    Disrupted myelin lipid metabolism differentiates frontotemporal dementia caused by GRN and C9orf72 gene mutations
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    Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders
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    Isoflurane Postconditioning Alleviates Ischemic Neuronal Injury via MiR-384-5p Regulated Autophagy
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    Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis
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  99. Nov 2022
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    A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice
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    GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines
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  103. Oct 2022
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    Circulating exosomal circRNA_0063476 impairs expression of markers of bone growth via the miR-518c-3p/DDX6 axis in ISS
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    In vivo characterization of Drosophila golgins reveals redundancy and plasticity of vesicle capture at the Golgi apparatus
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  112. Jun 2022
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    Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca2+ release from the ER
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    NRF2 Serves A Critical Role In Regulation Of Immune Checkpoint Proteins (ICPs) During Trophoblast Differentiation
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    Requirement of hippocampal DG nNOS-CAPON dissociation for the anxiolytic and antidepressant effects of fluoxetine
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  119. May 2022
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  122. Apr 2022
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    piRNA-guided intron removal from pre-mRNAs regulates density-dependent reproductive strategy
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    Extracellular tau oligomers affect extracellular glutamate handling by astrocytes through downregulation of GLT-1 expression and impairment of NKA1A2 function
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    Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
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  128. Mar 2022
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    Age-dependent release of high-mobility group box protein-1 and cellular neuroinflammation after traumatic brain injury in mice
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    ZFP541 maintains the repression of pre-pachytene transcriptional programs and promotes male meiosis progression
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    Sex-specific contribution of glucocorticoid receptor alpha isoforms to anxiety and depressive-like behavior in mice
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    CTNNBL1 restricts HIV-1 replication by suppressing viral DNA integration into the cell genome
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    The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity
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  136. Jan 2022
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    Selective autophagy controls innate immune response through a TAK1/TAB2/SH3PX1 axis
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  140. Dec 2021
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    SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes
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    Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer
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  145. Nov 2021
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    Dietary nitrate supplementation prevents radiotherapy-induced xerostomia
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load
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  150. Oct 2021
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    GABAB receptor signaling in the caudate putamen is involved in binge-like consumption during a high fat diet in mice
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  152. Sep 2021
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    Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
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    Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy
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    Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche
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    The Amot/integrin protein complex transmits mechanical forces required for vascular expansion
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    Sphingosine kinase 2 is essential for remyelination following cuprizone intoxication
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  163. link.springer.com link.springer.com
    Molecular analysis of cell survival and death pathways in the proteasome inhibitor bortezomib-resistant PC3 prostate cancer cell line
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    Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation
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  169. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High‐intensity treadmill running impairs cognitive behavior and hippocampal synaptic plasticity of rats via activation of inflammatory response
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      DOI: 10.1002/jnr.23996

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    Dysregulated NMDA-Receptor Signaling Inhibits Long-Term Depression in a Mouse Model of Fragile X Syndrome
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      DOI: 10.1523/JNEUROSCI.3038-15.2016

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    Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2
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    onlinelibrary.wiley.com/doi/abs/10.1002/cne.24589
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration
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  177. Jul 2021
  178. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The adenosine A2A receptor alleviates postoperative delirium-like behaviors by restoring blood cerebrospinal barrier permeability in rats
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15436
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum
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    ncbi.nlm.nih.gov/pmc/articles/PMC6483976/
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  181. www.sciencedirect.com www.sciencedirect.com
    On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons
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      RRID: AB_2305186

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    sciencedirect.com/science/article/pii/S2211124719314962
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    academic.oup.com/endo/article/160/1/101/5166846
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    Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation
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    RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo
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  188. www.jneurosci.org www.jneurosci.org
    Dysregulated NMDA-Receptor Signaling Inhibits Long-Term Depression in a Mouse Model of Fragile X Syndrome
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      RRID:AB_2305186

      DOI: 10.1523/JNEUROSCI.3038-15.2016

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      rabbit anti-u03b2 actin (1:2000, Abcam catalog #ab8227, RRID:AB_2305186

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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_2305186Cat

      DOI: 10.7554/eLife.44519

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  190. www.sciencedirect.com www.sciencedirect.com
    Beneficial effects of sound exposure on auditory cortex development in a mouse model of Fragile X Syndrome
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      RRID:AB_2

      DOI: 10.1016/j.nbd.2019.104622

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    sciencedirect.com/science/article/pii/S0969996119302979
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    N6-Methyladenosine Modification Controls Circular RNA Immunity
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      RRID:AB_230518

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    Intron-targeted mutagenesis reveals roles for Dscam1 RNA pairing architecture-driven splicing bias in neuronal wiring
    1
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      DOI: 10.1016/j.celrep.2021.109373

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  193. Jun 2021
  194. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Pentraxin 3 secreted by human adipose-derived stem cells promotes dopaminergic neuron repair in Parkinson's disease via the inhibition of apoptosis
    1
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      ab8227

      DOI: 10.1096/fj.202100408RR

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  195. www.sciencedirect.com www.sciencedirect.com
    Dietary supplementation of grape seed tannin extract stimulated testis development, changed fatty acid profiles and increased testis antioxidant capacity in pre-puberty hu lambs
    1
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      RRID:AB_2

      DOI: 10.1016/j.theriogenology.2021.06.015

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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses
    1
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      RRID:AB_2305186

      DOI: 10.1016/j.isci.2021.102548

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    ncbi.nlm.nih.gov/pmc/articles/PMC8184506/
  197. www.sciencedirect.com www.sciencedirect.com
    Protocol for evaluating autophagy using LysoTracker staining in the epithelial follicle stem cells of the Drosophila ovary
    1
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      RRID:AB_2305186

      DOI: 10.1016/j.xpro.2021.100592

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  198. www.sciencedirect.com www.sciencedirect.com
    Mammalian cells use the autophagy process to restrict avian influenza virus replication
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      RRID:AB_2305186

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  199. elifesciences.org elifesciences.org
    Distinct expression requirements and rescue strategies for BEST1 loss- and gain-of-function mutations
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      DOI: 10.7554/eLife.67622

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  200. www.frontiersin.org www.frontiersin.org
    Treponema denticola-Induced RASA4 Upregulation Mediates Cytoskeletal Dysfunction and MMP-2 Activity in Periodontal Fibroblasts
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      AB_2305186

      DOI: 10.3389/fcimb.2021.671968

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  201. www.sciencedirect.com www.sciencedirect.com
    Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
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      RRID:AB_2305186

      DOI: 10.1016/j.xpro.2021.100580

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  202. May 2021
  203. www.sciencedirect.com www.sciencedirect.com
    Class switching of Carbonic anhydrase isoforms mediates remyelination in CA3 hippocampal neurons during chronic hypoxia
    1
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      RRID:AB_2305186

      DOI: 10.1016/j.freeradbiomed.2020.09.029

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  204. www.sciencedirect.com www.sciencedirect.com
    Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells
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    1. scibot 12 May 2021
      RRID:AB_2305186

      DOI: 10.1016/j.celrep.2021.109120

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  205. www.sciencedirect.com www.sciencedirect.com
    Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses
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      RRID:AB_2305186

      DOI: 10.1016/j.isci.2021.102477

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  206. www.sciencedirect.com www.sciencedirect.com
    The Nrf2-mediated defense mechanism associated with HFE genotype limits vulnerability to oxidative stress-induced toxicity
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    sciencedirect.com/science/article/pii/S0300483X20301645
  207. www.sciencedirect.com www.sciencedirect.com
    Astrocyte glutamate transporters are increased in an early sporadic model of synucleinopathy
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      RRID:AB_2305186

      DOI: 10.1016/j.neuint.2020.104758

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  208. www.sciencedirect.com www.sciencedirect.com
    DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells
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      RRID:AB_2305186

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  209. www.sciencedirect.com www.sciencedirect.com
    Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation
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      RRID:AB_2305186

      DOI: 10.1016/j.molcel.2020.10.017

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    sciencedirect.com/science/article/pii/S1097276520307243
  210. Apr 2021
  211. www.sciencedirect.com www.sciencedirect.com
    Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells
    1
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      RRID:AB_2305186

      DOI: 10.1016/j.cmet.2020.07.008

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    sciencedirect.com/science/article/pii/S1550413120303661
  212. www.sciencedirect.com www.sciencedirect.com
    A pan-cancer transcriptome analysis of exitron splicing identifies novel cancer driver genes and neoepitopes
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      RRID:AB_2305186

      DOI: 10.1016/j.molcel.2021.03.028

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    sciencedirect.com/science/article/pii/S1097276521002239
  213. www.sciencedirect.com www.sciencedirect.com
    Quantitative chemoproteomics reveals O-GlcNAcylation of cystathionine γ-lyase (CSE) represses trophoblast syncytialization
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      DOI: 10.1016/j.chembiol.2021.01.024

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    sciencedirect.com/science/article/pii/S2451945621000507
  214. www.sciencedirect.com www.sciencedirect.com
    cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing
    1
    1. scibot 12 Apr 2021
      RRID:AB_2305186

      DOI: 10.1016/j.molcel.2021.01.024

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    sciencedirect.com/science/article/pii/S1097276521000447
  215. Mar 2021
  216. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enriched environment ameliorates chronic temporal lobe epilepsy‐induced behavioral hyperexcitability and restores synaptic plasticity in CA3–CA1 synapses in male Wistar rats
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    1. scibot 19 Mar 2021
      RRID:AB_2305186

      DOI: 10.1002/jnr.24823

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24823
  217. elifesciences.org elifesciences.org
    One-shot analysis of translated mammalian lncRNAs with AHARIBO
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    1. scibot 10 Mar 2021
      RRID:AB_2305186

      DOI: 10.7554/eLife.59303

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    elifesciences.org/articles/59303
  218. www.sciencedirect.com www.sciencedirect.com
    ER-directed TREX1 limits cGAS activation at micronuclei
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    1. scibot 01 Mar 2021
      RRID:AB_2305186

      DOI: 10.1016/j.molcel.2020.12.037

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    sciencedirect.com/science/article/pii/S1097276520309588
  219. Feb 2021
  220. www.sciencedirect.com www.sciencedirect.com
    The deubiquitinase TRABID stabilises the K29/K48-specific E3 ubiquitin ligase HECTD1
    1
    1. scibot 27 Feb 2021
      anti-β-actin

      DOI: 10.1074/jbc.RA120.015162

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    sciencedirect.com/science/article/pii/S0021925821000119
  221. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1‐dependent mitochondrial fission
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      RRID:AB_2305186

      DOI: 10.1111/jnc.15011

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15011
  222. www.cell.com www.cell.com
    Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
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      RRID:AB_2305186

      DOI: 10.1016/j.celrep.2020.01.013

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    cell.com/cell-reports/abstract/S2211-1247(20)30022-X
  223. Jan 2021
  224. www.sciencedirect.com www.sciencedirect.com
    Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution
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    1. scibot 27 Jan 2021
      RRID:AB_2305186

      DOI: 10.1016/j.celrep.2020.108670

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    sciencedirect.com/science/article/pii/S2211124720316594
  225. www.sciencedirect.com www.sciencedirect.com
    Attenuation of Antiviral Immune Response Caused by Perturbation of TRIM25-Mediated RIG-I Activation under Simulated Microgravity
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      RRID:AB_2305186

      DOI: 10.1016/j.celrep.2020.108600

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    sciencedirect.com/science/article/pii/S2211124720315898
  226. www.sciencedirect.com www.sciencedirect.com
    Ythdf m6A Readers Function Redundantly during Zebrafish Development
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      RRID:AB_2305186

      DOI: 10.1016/j.celrep.2020.108598

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    sciencedirect.com/science/article/pii/S2211124720315874
  227. Dec 2020
  228. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions
    1
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      RRID:AB_2305186

      DOI: 10.1093/hmg/ddaa209

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    ncbi.nlm.nih.gov/pmc/articles/PMC7689298/
  229. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Role of Tet2 in modulating neuronal morphology and cognition in a mouse model of Alzheimer's disease
    1
    1. scibot 07 Dec 2020
      rabbit anti‐beta actin

      DOI: 10.1111/jnc.15234

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15234
  230. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Slc26a6 is an apical membrane anion exchanger that drives HCO3−-dependent fluid secretion in murine pancreatic acinar cells
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      RRID:AB_2305186

      DOI: 10.1152/ajpcell.00257.2019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6957380/
  231. www.sciencedirect.com www.sciencedirect.com
    Keratinocyte-Macrophage Crosstalk by the Nrf2/Ccl2/EGF Signaling Axis Orchestrates Tissue Repair
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      DOI: 10.1016/j.celrep.2020.108417

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  232. Nov 2020
  233. www.cell.com www.cell.com
    An Aphid-Secreted Salivary Protease Activates Plant Defense in Phloem
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      RRID:AB_2305186

      DOI: 10.1016/j.cub.2020.09.020

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    cell.com/current-biology/abstract/S0960-9822(20)31351-8
  234. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of prostaglandin and E series prostaglandin receptor type 4 receptors in the development of bladder overactivity in a rat model of chemically induced prostatic inflammation
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      AB_2305186

      DOI: 10.1111/bju.14845

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  235. Oct 2020
  236. www.sciencedirect.com www.sciencedirect.com
    The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG
    1
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      RRID:AB_2305186

      DOI: 10.1016/j.celrep.2020.108295

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  237. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Heparan sulfate proteoglycan‐mediated dynamin‐dependent transport of neural stem cell exosomes in an in vitro blood‐brain barrier model
    1
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      β‐actin

      DOI: 10.1111/ejn.14974

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  238. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    IL-33 Alarmin and Its Active Proinflammatory Fragments Are Released in Small Intestine in Celiac Disease
    1
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      RRID:AB_2305186

      DOI: 10.3389/fimmu.2020.581445

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