447 Matching Annotations
  1. Nov 2024
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    Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer
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    sciencedirect.com/science/article/pii/S2589004224025082
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    Acute multi-level response to defective de novo chromatin assembly in S-phase
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    sciencedirect.com/science/article/pii/S1097276524008633
  4. Oct 2024
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    RNA polymerase II transcription initiation in holo-TFIID-depleted mouse embryonic stem cells
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    sciencedirect.com/science/article/pii/S2211124724011422
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    The TMEM132B-GABAA receptor complex controls alcohol actions in the brain
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    sciencedirect.com/science/article/pii/S0092867424010249
  7. Sep 2024
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    A candidate loss-of-function variant in SGIP1 causes synaptic dysfunction and recessive parkinsonism
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    sciencedirect.com/science/article/pii/S2666379124004798
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    Intranuclear immunostaining-based FACS protocol from embryonic cortical tissue
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    The alternative regenerative strategy of bearded dragon unveils the key processes underlying vertebrate tooth renewal
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  11. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Reproducible Differentiation of Human Pluripotent Stem Cells into Two-Dimensional Cortical Neuron Cultures with Checkpoints for Success
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    Spastin regulates ER-mitochondrial contact sites and mitochondrial homeostasis
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    Miniature linear and split-belt treadmills reveal mechanisms of adaptive motor control in walking Drosophila
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  14. Aug 2024
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    Opposing GPCR signaling programs protein intake setpoint in Drosophila
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    Rapid reorganization of serotonin projections and antidepressant response to 5-HT1A-biased agonist NLX-101 in fluoxetine-resistant cF1ko mice.
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    Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS
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    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
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  19. Jul 2024
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    Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes
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  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-genomic ERα-AMPK signaling regulates sex-dependent Bcrp transport activity at the blood-brain barrier
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      DOI: 10.1210/endocr/bqae081

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    Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1535610824002393
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    Assembly mechanism of Integrator’s RNA cleavage module
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    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
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      DOI: 10.1126/science.adh4567

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  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sub-membrane actin rings compartmentalize the plasma membrane
    1
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      DOI: 10.1083/jcb.202310138

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  26. 52.53.155.43 52.53.155.43
    mmc1-html.html
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    Dynamic assemblies of parvalbumin interneurons in brain oscillations
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  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhalation of hydrogen gas mitigates sevoflurane-induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation
    1
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      DOI: 10.1111/jnc.16142

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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mushroom body output neurons MBON-a1/a2 define an odor intensity channel that regulates behavioral odor discrimination learning in larval Drosophila
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      DOI: 10.3389/fphys.2023.1111244

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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunofluorescence and image analysis pipeline for Drosophila motor neurons
    1
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      DOI: 10.1093/biomethods/bpz010

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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Presynaptic inhibition selectively suppresses leg proprioception in behaving Drosophila
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibitory circuits coordinate leg movements during Drosophila grooming
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  33. www.biorxiv.org www.biorxiv.org
    Neuronal identity control at the resolution of a single transcription factor isoform
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatially distinct epithelial and mesenchymal cell subsets along progressive lineage restriction in the branching embryonic mammary gland
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      DOI: 10.1038/s44318-024-00115-3

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  35. Jun 2024
  36. www.cell.com www.cell.com
    Moderate-intensity aerobic exercise training improves CD8+ tumor-infiltrating lymphocytes effector function by reducing mitochondrial loss.
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    Setdb1 protects genome integrity in murine muscle stem cells to allow for regenerative myogenesis and inflammation
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Odorant receptor co-receptors affect expression of tuning receptors in Drosophila
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    Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
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  40. May 2024
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    Axonal endoplasmic reticulum tubules control local translation via P180/RRBP1-mediated ribosome interactions
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    The Cryptosporidium signaling kinase CDPK5 plays an important role in male gametogenesis and parasite virulence
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    Elevated sleep quota in a stress-resilient Drosophila species
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    sciencedirect.com/science/article/pii/S0960982224005347
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    Innervation of nociceptor neurons in the spleen promotes germinal center responses and humoral immunity
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    Viral mimicry and memory deficits upon microglial deletion of ATRX
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    NRP1 is a receptor for mammalian orthoreovirus engaged by distinct capsid subunits
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      DOI: 10.1016/j.chom.2024.04.014

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  47. Apr 2024
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    Adipocyte-Released Adipomes in Chagas Cardiomyopathy: Impact on Cardiac Metabolic and Immune Regulation
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    TBL38 atypical homogalacturonan-acetylesterase activity and cell wall microdomain localization in Arabidopsis seed mucilage secretory cells
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    DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice
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    Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
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    Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis
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    Decreases in the number of microglia and neural circuit dysfunction elicited by developmental exposure to neonicotinoid pesticides in mice
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    Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer
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    Microtubule-associated protein MAP7 promotes tubulin posttranslational modifications and cargo transport to enable osmotic adaptation
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    Bacopa monnieri phytochemicals regulate fibroblast cell migration via modulation of focal adhesions
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  58. Mar 2024
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    Derivation of functional thymic epithelial organoid lines from adult murine thymus
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    Generation of a patient-specific induced pluripotent stem cell line carrying the DES p.R406W mutation, an isogenic control and a DES p.R406W knock-in line
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    Single-cell omics identifies inflammatory signaling as a trans-differentiation trigger in mouse embryos
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    Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
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    TLR2 regulates hair follicle cycle and regeneration via BMP signaling
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    Type-I-interferon-responsive microglia shape cortical development and behavior
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    Translocation across a human enteroid monolayer by zoonotic Streptococcus suis correlates with the presence of Gb3-positive cells
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    Atypical cofilin signaling drives dendritic cell migration through the extracellular matrix via nuclear deformation
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    Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1
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    Evolutionary analysis identifies a Golgi pathway and correlates lineage-specific factors with endomembrane organelle emergence in apicomplexans
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    Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury
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    Histological and biochemical changes in lymphatic vessels after skeletal muscle injury induced by lengthening contraction in male mice
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    Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment
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    Cytoneme signaling provides essential contributions to mammalian tissue patterning
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    Therapy-induced normal tissue damage promotes breast cancer metastasis
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    Gbb glutathionylation promotes its proteasome-mediated degradation to inhibit synapse growth
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    Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells
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    Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling
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    Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy
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    YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration
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    Distinctive Interactomes of RNA polymerase II phosphorylation during different stages of transcription
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  89. 52.53.155.43 52.53.155.43
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    Protocol for establishing primary human lung organoid-derived air-liquid interface cultures from cryopreserved human lung tissue
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  91. Nov 2023
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    Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities
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    Generation of four gene-edited human induced pluripotent stem cell lines with mutations in the ATM gene to model Ataxia-Telangiectasia
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    Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis
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  95. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Comparative neuroanatomy of the central nervous system in web-building and cursorial hunting spiders
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination in male mice
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq
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  98. www.biorxiv.org www.biorxiv.org
    Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1
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  99. Oct 2023
  100. www.sciencedirect.com www.sciencedirect.com
    The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment
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    Deep scRNA sequencing reveals a broadly applicable Regeneration Classifier and implicates antioxidant response in corticospinal axon regeneration
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    Intravital microscopy of satellite cell dynamics and their interaction with myeloid cells during skeletal muscle regeneration
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    Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism
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    Reciprocal transmission of activating and inhibitory signals and cell fate in regenerating T cells
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    Microvascular smooth muscle cells exhibit divergent phenotypic switching responses to platelet-derived growth factor and insulin-like growth factor 1
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    Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth
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    Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony
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    Thalamocortical control of cell-type specificity drives circuits for processing whisker-related information in mouse barrel cortex
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    Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia
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    Distinctive Interactomes of RNA polymerase II phosphorylation during different stages of transcription
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  112. Aug 2023
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors
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    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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    Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis
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    Senescent cells form nuclear foci that contain the 26S proteasome
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    Exosomal release of the virus-encoded chemokine receptor US28 contributes to chemokine scavenging
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  119. Jul 2023
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    Golgi polarity shift instructs dendritic refinement in the neonatal cortex by mediating NMDA receptor signaling
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    Glycosaminoglycans and fucoidan have a protective effect on experimental glomerulonephritis
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Ex Vivo Model to Study Therapeutic Treatments for Myelin Repair following Ischemic Damage
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    Macrophages drive KSHV B cell latency
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    Imbalance of helper T cell subtypes and adipokine secretion in perivascular adipose tissue as a trigger of atherosclerosis in chronic Porphyromonas gingivalis W83 infection
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  125. Jun 2023
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    Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice
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    Selective Block of Upregulated Kv1.3 Potassium Channels in ON-Bipolar Cells of the Blind Retina Enhances Optogenetically Restored Signaling
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    Fluorescence-microscopy-based assay assessing regulatory mechanisms of global genome nucleotide excision repair in cultured cells
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  129. www.biorxiv.org www.biorxiv.org
    Cyclophosphamide induces the loss of taste bud innervation in mice
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  130. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genetic ablation of Saposin-D in Krabbe disease eliminates psychosine accumulation but does not significantly improve demyelination
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    The Rab5 effector FERRY links early endosomes with mRNA localization
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  132. May 2023
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    Isolation and Characterization of Adult Cardiac Fibroblasts and Myofibroblasts
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    Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma
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    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila Tachykininergic Neurons Modulate the Activity of Two Groups of Receptor-Expressing Neurons to Regulate Aggressive Tone
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    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    Ubiquitin proteomics identifies RNA polymerase I as a target of the Smc5/6 complex
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    Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice
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    Immune mechanisms shape the clonal landscape during early progression of prostate cancer
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    The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging
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    Unidirectional and phase-gated signaling synchronizes murine presomitic mesoderm cells
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    The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation
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    Mechanism of interdigitation formation at apical boundary of MDCK cell
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    Brain-specific glycosylation of protein tyrosine phosphatase receptor type Z (PTPRZ) marks a demyelination-associated astrocyte subtype
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    Sodium ion influx regulates liquidity of biomolecular condensates in hyperosmotic stress response
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    A timer gene network is spatially regulated by the terminal system in the Drosophila embryo
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  149. Mar 2023
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    The protective effects of a novel AT2 receptor agonist, β-Pro7Ang III in ischemia-reperfusion kidney injury
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    Multiplex translaminar imaging in the spinal cord of behaving mice
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    Neprilysin-sensitive amyloidogenic Aβ versus IDE-sensitive soluble Aβ: a probable mechanistic cause for sporadic Alzheimer’s disease
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    Non-muscle myosin II drives critical steps of nematocyst morphogenesis
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    Simultaneous activation of Tor and suppression of ribosome biogenesis by TRIM-NHL proteins promotes terminal differentiation
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    Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye
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    Seeking the Amygdala: Novel Use of Diffusion Tensor Imaging to Delineate the Basolateral Amygdala
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  157. Feb 2023
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    RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex
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    Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology
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  160. Jan 2023
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    Characterization of the structure and control of the blood-nerve barrier identifies avenues for therapeutic delivery
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    A single RET mutation in Hirschsprung disease induces intestinal aganglionosis via a dominant-negative mechanism
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    Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance
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    A porcine islet-encapsulation device that enables long-term discordant xenotransplantation in immunocompetent diabetic mice
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    Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals
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  169. Nov 2022
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    Single cell sequencing maps skeletal muscle cellular diversity as disease severity increases in dystrophic mouse models
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    Cephalopod retinal development shows vertebrate-like mechanisms of neurogenesis
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    NEIL3 contributes to the Fanconi anemia/BRCA pathway by promoting the downstream double-strand break repair step
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  174. Oct 2022
  175. alzres.biomedcentral.com alzres.biomedcentral.com
    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
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  176. Sep 2022
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    Continuous double-strand break induction and their differential processing sustain chiasma formation during Caenorhabditis elegans meiosis
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    Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis
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    Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock
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    Ubiquitin profiling of lysophagy identifies actin stabilizer CNN2 as a target of VCP/p97 and uncovers a link to HSPB1
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    The ER ladder is a unique morphological feature of developing mammalian axons
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    Genetic deletion of the glucocorticoid receptor in Cx3cr1+ myeloid cells is neuroprotective and improves motor recovery after spinal cord injury
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    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
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    Full-length and split-NanoLuc reporters identify pathogenic COL4A5 nonsense mutations susceptible to premature termination codon readthrough
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    Protocol for generating a mouse model of gastric MALT lymphoma and the identification of MALT lymphoma cell populations by immunostaining
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