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Selective MOSPD2-STARD3 interaction at ER contact sites governs late endosome/lysosome dynamics and cholesterol homeostasis

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  DOI: 10.64898/2026.03.30.714413
  
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Insights into the zebrafish left–right organizer's centrosomes and cilia via volume electron microscopy

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  DOI: 10.1242/bio.062489
  
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Genome editing of a low-penetrance albinism-associated variant in TYR in patient-derived pluripotent stem cells

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  DOI: 10.1101/2025.07.14.664762
  
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The mechanistic basis of cargo selection during Golgi maturation

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54.241.53.176/d0c9b630f7bec788d8c263b9282879876f022cb4/2025.06.26.661719v1.full-html.html
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Species-specific cleavage of the autophagy adaptor p62 dictates responses to TNF

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Chaperonin TRiC bridges radial spokes for folding locally translated proteins to sustain mammalian sperm flagellar motility

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1-s2.0-S2589004226010047-main-html.html

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Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance

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  DOI: 10.1016/j.celrep.2026.117244
  
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sciencedirect.com/science/article/pii/S2211124726003220
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BRCA2-dependent maturation of nascent strands during DNA replication

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  DOI: 10.1016/j.molcel.2026.03.012
  
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Achieving cell-type specific transduction with adeno-associated viral vectors in pigeons

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  DOI: 10.1016/j.crneur.2026.100157
  
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Apr 2026
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Distinct postsynaptic morphogenetic strategies across Drosophila embryonic muscles during neuromuscular junction formation

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  DOI: 10.64898/2026.03.20.713228
  
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2026.03.17.712218.full-html.html

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2026.03.11.711111.full-html.html

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54.241.53.176/921642716d9552753369685b40525ca6d839c162/2026.03.11.711111.full-html.html
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Noninvasive tactile stimulation engaging a thalamic-amygdala circuit ameliorates mood dysfunction in mouse models of depression-like behavior

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  DOI: 10.1016/j.neuron.2026.03.012
  
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Effects of neuromelanin buildup in rodent nigral dopamine neurons: implications for sex-biased vulnerability in Parkinson's disease

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1. scibot 02 Apr 2026
  
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  DOI: 10.1016/j.nbd.2026.107378
  
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2026.03.23.713591.full-html.html

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  DOI: 10.64898/2026.03.23.713591
  
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54.241.53.176/e583a14afdc4fabf54fb98e28959712dad965ac3/2026.03.23.713591.full-html.html
Mar 2026
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Simulated microgravity alters sperm navigation, fertilization and embryo development in mammals

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1. scibot 31 Mar 2026
  
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  DOI: 10.1038/s42003-026-09734-4
  
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nature.com/articles/s42003-026-09734-4
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Piezo1-mediated mechanotransduction in choroid plexus epithelial cells governs ciliogenesis and cerebrospinal fluid homeostasis

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.neuron.2026.02.033
  
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Molecular brake on firing pattern transitions in MHbChAT neurons to mediate nicotine-withdrawal-induced anxiety

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  DOI: 10.1016/j.neuron.2026.02.020
  
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NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme K+ T cells

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.016
  
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Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines

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  DOI: 10.1016/j.crmeth.2026.101371
  
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Assessing leaky expression of Cre-dependent DNA constructs in the mouse genome using sensitive bioluminescent reporters

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  DOI: 10.1016/j.crmeth.2026.101369
  
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Rapid expansion of primary human vocal fold epithelial cells via targeted pathway inhibition and anchorage-independent sphere culture

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  DOI: 10.1016/j.crmeth.2026.101310
  
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CBLN2 promoter enables genetic access to wide-field neurons of the tree shrew superior colliculus

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  DOI: 10.1016/j.crmeth.2026.101309
  
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Reshaping the progranulin/sortilin interaction for targeted degradation of extracellular proteins

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  DOI: 10.1016/j.chembiol.2026.03.002
  
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Targeting PI3Kδ suppresses pancreatic cancer by dual disruption of fibrosis and immune evasion

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  DOI: 10.1016/j.celrep.2026.117188
  
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A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy

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  DOI: 10.1016/j.cell.2026.03.002
  
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Generation of four induced pluripotent stem cell lines from Korean patients with Huntington’s disease (IPBi001-A, IPBi002-A, IPBi003-A, IPBi004-A)

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.scr.2026.103963
  
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Sex-specific APOE4-dependent innate immunity regulates meningeal lymphatics, brain lipids, neuroinflammation, and cognition

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  DOI: 10.1016/j.neuron.2026.02.030
  
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Microglia-mediated protection against Alzheimer’s disease pathology and detrimental effects in white matter revealed by Ptpn6 deletion

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  DOI: 10.1016/j.neuron.2026.02.023
  
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Generation and characterization of induced pluripotent stem cell (iPSC) lines from patients affected with Tay-Sachs and Sandhoff disease

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  DOI: 10.1016/j.scr.2026.103949
  
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Hindbrain neurons that underlie water discrimination and consumption

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1. scibot 26 Mar 2026
  
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  DOI: 10.1016/j.cub.2026.02.058
  
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Targeting P2RY2 reprograms tumor immunity and inhibits tumor growth in non-small cell lung cancer

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1. scibot 26 Mar 2026
  
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  DOI: 10.1016/j.canlet.2026.218448
  
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sciencedirect.com/science/article/pii/S0304383526002119
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Introducing PIGMO, a novel PIGmented MOuse model of Parkinson’s disease

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1. scibot 24 Mar 2026
  
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  DOI: 10.1038/s41531-026-01289-9
  
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Disruption of WNT/Notch signaling in pancreatic cancer reveals tumors depend on the intricate equilibrium of malignant cell states

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Natural killer cell dysfunction drives keloid pathogenesis

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Aging disrupts sympathetic innervation of the thymus

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Modeling embryonic heart vascular plexus development and sympathetic innervation on a human heart organoid

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2026.03.10.710589.full-html.html

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iyer-et-al-2026-neuropeptide-y-and-peptide-yy-differentially-modulate-bitter-and-fatty-acid-evoked-responses-in-human-html.html

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Microglia Pyroptosis-Derived IL-18 Drives White Matter Injury in Developing Brain following Hypothermic Hypoxia-Ischemia

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Combining lenalidomide with IL-2 family of cytokines enhances activating receptor and perforin/granzyme expression in NK cells

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Genome-wide CRISPR screen identifies neddylation as a regulator of neuronal aging and AD neurodegeneration

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The landscape of gene mutations in a cohort of 3353 Han Chinese children with nonsyndromic hearing loss

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Targeting PGAM5-driven mitochondrial integrated stress response slows ALS progression across subtypes

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Non-polio enterovirus infection and electrophysiological changes in human iPSC-derived neural networks

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Vitamin C inhibits ACSL4 to alleviate ferro-aging in primates

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Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy

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Single-Nucleus Transcriptomics Reveals Cell Type-Specific Remodeling and Epilepsy-Associated Microglia

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Enhanced Spatial Mapping of Mouse Gastric Muscle Layers Using a Modified Swiss Roll Technique

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Generation and characterization of human induced pluripotent stem cells from neuropathologically confirmed multiple system atrophy patient-derived fibroblasts

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BAF60C links nucleolar stress to β cell dysfunction in type 2 diabetes through controlling Reg3b mRNA decay

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Modeling human prenatal adrenocortical functional zonation dynamics from pluripotent stem cells

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Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema

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AxoMetric platform facilitates rapid and unbiased automated quantification of axon regeneration in tissue sections

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Sex differences in corticotropin-releasing factor receptor-2α expressing neurons in acutely stressed mice

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A strategy of microglia replacement alleviates microgliopathy in a CSF1R I794T hotspot mutation mouse model of CSF1R-related disorder

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Generation of the induced pluripotent stem cell line BTHBIOi002-A derived from a USH2 patient with c.2512C>T and c.2802T>G mutations in USH2A gene

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Rapamycin Reduces Amyloid‐β Plaques and Improves Behavioral Performance in a Sex‐Dependent Manner in Mouse Models of Amyloidosis

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Feb 2026
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Deficiency of Pdap1 Results in Embryonic Lethality and Diminished Vascularization

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Generation and characterization of POMC-tdTomato reporter human pluripotent stem cell lines

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CXCR2 affects sensitization of radioresistant HPV-negative head and neck squamous cell carcinoma cells by ABT-263

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Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity

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Regulation of mitophagy by Fis1 and Fascin1-organized actin

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Nonsense-mediated mRNA decay orchestrates neuronal migration and cortical lamination while modulating Reelin and ciliary gene regulatory networks

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Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease

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Messenger RNA delivery to islet β cells using conjugated lipid nanoparticles

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Distinct spatial patterning and transcriptomic landscapes of human neural organoids by localized delivery of morphogens

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More than microglial depletion: PLX5622 activates the hepatic constitutive androstane receptor to alter anesthesia and addiction

1
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54.241.53.176 54.241.53.176

1-s2.0-S2352345X26000330-main-html.html

1
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54.241.53.176 54.241.53.176

1-s2.0-S2589004226004773-main-html.html

1
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Unveiling critical signaling pathways in the murine salivary gland and the role of midkine

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Global mapping of circRNA-target RNA interactions reveal P-body-mediated translational repression

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Insolubilome profiling defines molecular features that influence protein insolubility with aging

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Red blood cells serve as a primary glucose sink to improve glucose tolerance at altitude

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Single-cell multi-omic analyses highlight the essential role of NKX2.2-CLEC16A/endosomal pathway for human pancreatic differentiation and function

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Induction of neurodegeneration in the hippocampus of senescence-accelerated mouse-prone 8 (SAMP8) mice by blood-brain barrier-crossing serum amyloid P component

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  DOI: 10.1186/s12974-026-03704-7
  
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54.241.53.176 54.241.53.176

1-s2.0-S2589004226004530-main-html.html

1
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Deletion of Mfn2 in endothelial cells triggers a mitohormetic response that improves systemic metabolism and healthspan in mice

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Cognitive rejuvenation through partial reprogramming of engram cells

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  DOI: 10.1016/j.neuron.2025.11.028
  
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A Plastic EMP1+ to LGR5+ Cell State Conversion as a Bypass to KRASG12D Pharmacologic Inhibition in Metastatic Colorectal Cancer

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Cleavage of mRNAs by a minority of pachytene piRNAs improves sperm fitness

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Dorsoventral-mediated Shh induction is required for axolotl limb regeneration

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  DOI: 10.7554/eLife.106917
  
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A Common Iba1 Antibody Labels Vasopressin Neurons in Mice

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Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy

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Converging dopamine pathways onto basolateral amygdala neurons encode exploration decisions

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Selective adhesion preserves eye patterning as axonal retinotopy in the Drosophila brain

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Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles

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  DOI: 10.1016/j.crmeth.2025.101295
  
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ATP7B-maintained copper stores in myeloid progenitors are required for functional maturation of neutrophils

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Selenoprotein P deletion ameliorates metabolic stress-associated anxiety-like behavior in male mice

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Dynamic and differential renal cortical cell-specific mitochondrial metabolism in response to fasting

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  DOI: 10.1152/ajprenal.00235.2025
  
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52.53.155.43 52.53.155.43

2025.09.03.673267v1.full-html.html

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Jan 2026
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Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection

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In vivo AGO-APP for cell-type- and compartment-specific miRNA profiling in the mouse brain

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NUSAP1 Recruits DAXX to Suppress HIF‐Driven Triple‐Negative Breast Cancer Progression

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  DOI: 10.1002/advs.202513380
  
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MITF, TFEB, and TFE3 drive distinct adaptive gene expression programs and immune infiltration in melanoma

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  DOI: 10.1016/j.celrep.2025.116499
  
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Transsynaptic tracing techniques to interrogate neuronal connectivity of glioblastomas

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  DOI: 10.1038/s41596-025-01287-w
  
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54.241.53.176 54.241.53.176

1-s2.0-S2589004226001161-main-html.html

1
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Tumor-associated macrophages enhance peripheral nerve tumor infiltration and spinal cord repair

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  DOI: 10.1016/j.immuni.2025.12.016
  
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NuMA promotes constitutive heterochromatin compaction by stabilizing linker histone H1 on chromatin

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  DOI: 10.1016/j.celrep.2025.116901
  
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Airway injury induces alveolar epithelial responses mediated by macrophages

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  DOI: 10.1016/j.celrep.2025.116881
  
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Neuropathic pain-like responses in a chronic CNS injury model are mediated by corticospinal-targeted spinal interneurons

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  DOI: 10.1523/JNEUROSCI.1264-24.2025
  
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Partial Deletion of Cxcl12 from Hippocampal Cajal–Retzius Cells Does Not Disrupt Dentate Gyrus Development or Neurobehaviors

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54.241.53.176 54.241.53.176

Optimization of oxygen concentration and glycosphingolipid effects on spermatogenesis in mouse testicular culture

2
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  DOI: 10.1093/biolre/ioaf284
  
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The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis

1
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YAP/TAZ-VGLL3 governs adipocyte fate via epigenetic reprogramming of PPARγ and its target enhancers

1
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Targeting TCF21-TCF3 heterodimer in tumor-associated pericytes attenuates hematogenous metastasis by restoring pericyte gatekeeper function

1
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1-s2.0-S2589004226000933-main-html.html

1
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Inducible deletion of DGAT1 and 2 from microglia exacerbates neurodegeneration and endolysosomal lipid accumulation in male PS19 mice

1
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Optimized selection of specific antibodies against rodent ESR1 proteins and their application for immunohistochemistry and dual immunohistofluorescence with the specific anti-ESR2 antibody PPZ0506

1
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Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

1
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54.241.53.176 54.241.53.176

2026.01.05.697593v1.full-html.html

1
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2026.01.07.694713v1.full-html.html

1
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Activation of a branched-chain amino acid rheostat restores replication-dependent hematopoietic stem cell fitness

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1-s2.0-S2589004226000696-main-html.html

1
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Microenvironmental TGF-β is an early driver of NF1-associated tumor formation

1
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Tissue-specific restriction of transposon-derived regulatory elements safeguards cell-type identity

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Aberrant calcium signaling and neuronal activity in the L271H CACNA1D (Cav1.3) iPSC model of neurodevelopmental disease

3
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  DOI: 10.1038/s41380-025-03429-8
  
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Plasticity of synapses innervating spinal motor neurons after spinal cord injury in rhesus monkeys

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Retinal ganglion cell survival and functional maturation in transiently vascularized human retinal organoids

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Generation of RB1 knockout human embryonic stem cell lines derived from H9 using CRISPR/Cas9

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Tachykinin signaling defines distinct populations of glia in the enteric nervous system

1
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State-specific enhancer landscapes govern microglial plasticity

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Rothia mucilaginosa membrane vesicles stabilize labile iron to alleviate UVB-induced ferroptosis

1
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The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulates the Functional Output of Human Taste Bud Cells

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  DOI: 10.64898/2025.12.31.697221
  
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Assessing the barrier function of the retinal pigment epithelium in adult mice using transepithelial electrical resistance measurements and quantitative immunohistochemistry

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  DOI: 10.1016/j.exer.2025.110817
  
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Dec 2025
54.241.53.176 54.241.53.176

Neurexin regulates mechanical nociceptive sensitization by central inhibition in Drosophila

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3D post-implantation co-culture of human embryo and endometrium

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Establishment of six human induced pluripotent stem cell lines from healthy Central Asian donors (IPBi115-A, IPBi116-A, IPBi117-A, IPBi119-A, IPBi124-A, and IPBi129-A)

1
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Muscle satellite cell editing by LNP-CRISPR-Cas9 to resist muscle injury

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Modeling human embryo implantation in vitro

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  DOI: 10.1016/j.cell.2025.10.027
  
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2025.12.08.693069.full-html.html

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Histamine H3 Receptor Antagonist, Thioperamide, Improves Behavioral and Neuropathological Changes Associated with Subclinical Hypersensitivity to a Cow’s Milk Allergen

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Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity

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  DOI: 10.1016/j.immuni.2025.11.020
  
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Electroacupuncture suppresses premature ventricular complexes occurring post-myocardial infarction through corticothalamic circuit

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Biogenesis and migration of the sperm cytoplasmic droplet require ARRDC5 and TEX38

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Intravital observation of neuronal and immune cell dynamics in the developing mammalian brain

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Protocol for generation of endothelial cells from human-derived iPSCs and integration into mouse brain explants

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1-s2.0-S2589004225026860-main-html.html

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Locus coeruleus microcircuitry processes periaqueductal gray inputs into distinct outputs for regulation of pain and anxiety

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MeCP2 regulates telencephalic development in human cerebral organoids

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The exit of naive pluripotency contains a metabolism-induced checkpoint for telomere homeostasis

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A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis

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Astrocytic Interleukin-33 Deficiency Reduces Glial Fibrillary Acidic Protein Expression and Exacerbates Microglial Activation and Neuronal Damage in a Chemically Induced Inflamed Frontal Cortex

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Sensitized mast cells for targeted drug delivery and augmented cancer immunotherapy

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Context-dependent inhibitory roles of RhoA in 3D invasive cell migration within the extracellular matrix

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Jub-induced phosphorylation of Warts inhibits its activity and recruitment into biomolecular condensates

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Toggle-Untoggle – a cell segmentation tool with an interactive user verification interface

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BPS Publications

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Graded Hair Cell Ablation Reveals Functional Redundancy in the Mature Mouse Vestibular System

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Spatial Myeloid Landscape of Large Artery Atherosclerotic and Cardioembolic Thrombi Retrieved by Mechanical Thrombectomy

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A bacterial toxin as a novel anti-cancer drug modulating the tumor-microenvironment

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Excessive vigorous exercise impairs cognitive function through a muscle-derived mitochondrial pretender

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Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control

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Dual role of Oct4 and Sox2 in controlling the developmental capacity and timing of tissue morphogenesis in the embryonic lineage

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Orexinergic lateral hypothalamus-anterior cingulate cortex circuit alleviates chronic stress-induced anxiety-like behaviors

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Hierarchical regulation of cerebellar neurogenesis by Sin3A-mediated gene repression

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Developmental CA2 perineuronal net reduction restores social memory in Shank3B KO mice

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Jun N-terminal kinase's role in neuropathic pain: C-fiber remodeling and growth-associated protein-43 phosphorylation

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2025.11.16.688689v1.full-html.html

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C5aR1+ microglia exacerbate neuroinflammation and cerebral edema in acute brain injury

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Phenotype specific nuclear lamina remodeling in hiPSC derived cardiomyocytes bearing TNNT2 sarcomeric variants

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Inhibitory inputs from thalamus promote resilient spiking in tail of striatum

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Variability vs. phenotype: Multimodal analysis of Dravet syndrome brain organoids powered by deep learning

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ERK activation dynamics in maturing oocyte controls embryonic nuclear divisions in Caenorhabditis elegans

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NLRP3 inflammasome-dependent and -independent interleukin-1β release by macrophages exposed to wear and corrosion products from CoCrMo implants

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Modeling antithymocyte globulin-induced microvasculopathy using human iPSC-derived vascularized liver organoids

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  DOI: 10.1016/j.xcrm.2025.102433
  
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Regulatory T cell stability determines the efficiency of bile duct regeneration during cholangitis

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2025.11.11.687663v1.full-html.html

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Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution

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Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs

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Thermoresponsive motor behavior is mediated by ring neuron circuits in the central complex of Drosophila

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2025.11.05.686656v1.full-html.html

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Nuclear-lamin-guided plastic positioning and folding of the human genome

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A phenotypic brain organoid atlas and biobank for neurodevelopmental disorders

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A myeloid Tet2-IL-1β axis modulates intestinal inflammation by restricting catecholaminergic stimulation of enterochromaffin cell differentiation

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Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation

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A heterozygous USB1 variant linked to immunodeficiency

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N6-methyladenosine on L1PA governs the trans-silencing of LTRs and restrains totipotency in naive human embryonic stem cells

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The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells

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3D-generation of high-purity midbrain dopaminergic progenitors and lineage-guided refinement of grafts supports Parkinson’s disease cell therapy

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Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling

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Enhanced hybridization-proximity labeling discovers protein interactomes of single RNA molecules

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Cholinergic interneurons of the dorsomedial striatum mediate winner-loser effects on social hierarchy dynamics in male mice

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Microglial NLRP3 inflammasome activation leads to perineuronal net loss in cocultured neurons

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The gain-of-function TREM2-T96K mutation increases risk for Alzheimer’s disease by impairing microglial function

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Optogenetic stimulation of midbrain dopaminergic neurons rescues hippocampal synaptic plasticity deficits in a mouse model of Alzheimer’s disease

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Midbrain degeneration triggers astrocyte reactivity and tau pathology in experimental Alzheimer’s Disease

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Vitamin C conveys geroprotection on primate ovaries

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Characterization of the dual functions of Leishmania CK1.2 in both the parasite and the macrophage using integrated proteomics and spatial mapping

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Integrated omics reveals disease-associated radial glia-like cells with epigenetically dysregulated interferon response in multiple sclerosis

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The p75 neurotrophin receptor controls the skeletal stem cell niche through sensory innervation

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Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis

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Generation and validation of a iPSC line from a healthy female donor using integration-free Sendai virus reprogramming

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Rac1 inhibition prevents axonal cytoskeleton dysfunction in transthyretin amyloid polyneuropathy

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