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    Identification of Predictive ERBB Mutations by Leveraging Publicly Available Cell Line Databases
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      DOI: 10.1158/1535-7163.MCT-20-0590

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    BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer
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    Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription
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    Frontiers | Gestodene, a novel positive allosteric modulator of PAR1, enhances PAR1-mediated human platelet aggregation
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    Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610824003179
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    Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell
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    JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma
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    The Orphan G Protein‐coupled Receptor 75 Signaling is Activated by the Chemokine CCL5
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    Exposure to far‐infrared ray attenuates methamphetamine‐induced impairment in recognition memory through inhibition of protein kinase C δ in male mice: Comparison with the antipsychotic clozapine
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    1. scibot 25 Sep 2024
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  11. Sep 2024
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    Key roles of C2/GAP domains in SYNGAP1-related pathophysiology
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    sciencedirect.com/science/article/pii/S2211124724010842
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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    Anti-HDGF antibody targets EGFR tyrosine kinase inhibitor-tolerant cells in NSCLC patient-derived xenografts
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    Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation
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  16. Aug 2024
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    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
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    Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance
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    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
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  20. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    cell.com/cell/fulltext/S0092-8674(20)30163-X
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    Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy
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    Disc Large Homolog 1 Is Critical for Early T Cell Receptor Micro Cluster Formation and Activation in Human T Cells
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  23. pubs.acs.org pubs.acs.org
    Linking Hypothermia and Altered Metabolism with TrkB Activation
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    Purinergic receptor P2Y6 contributes to 1‐methyl‐4‐phenylpyridinium‐induced oxidative stress and cell death in neuronal SH‐SY5Y cells
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    1. scibot 02 Aug 2024
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    Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function
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  26. Jul 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC
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    Apocynin Prevents Cigarette Smoke-Induced Anxiety-Like Behavior and Preserves Microglial Profiles in Male Mice
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    Impact of Interleukin-6 Activation and Arthritis on Epidermal Growth Factor Receptor (EGFR) Activation in Sensory Neurons and the Spinal Cord
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    Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling
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    Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization
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    G protein–coupled receptor endocytosis generates spatiotemporal bias in β-arrestin signaling
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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    wang-et-al-2024-lilrb1-hla-g-axis-defines-a-checkpoint-driving-natural-killer-cell-exhaustion-in-tuberculosis-html.html
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    LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis
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    Cenicriviroc Suppresses and Reverses Steatohepatitis by Regulating Macrophage Infiltration and M2 Polarization in Mice
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      DOI: 10.1210/endocr/bqae069

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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A methodology to globally assess ectodomain shedding using soluble fractions from the mouse brain
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer
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  39. Jun 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target
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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer
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  42. May 2024
  43. www.mdpi.com www.mdpi.com
    Lysophosphatidic Acid Stimulates Mitogenic Activity and Signaling in Human Neuroblastoma Cells through a Crosstalk with Anaplastic Lymphoma Kinase
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  44. 52.53.155.43 52.53.155.43
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    Novel therapeutic strategies targeting bypass pathways and mitochondrial dysfunction to combat resistance to RET inhibitors in NSCLC
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  82. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Axon-derived PACSIN1 binds to the Schwann cell survival receptor, LRP1, and transactivates TrkC to promote gliatrophic activities
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    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
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  84. www.sciencedirect.com www.sciencedirect.com
    Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma
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    mTOR regulates mineralocorticoid receptor transcriptional activity by ULK1- dependent and independent mechanisms
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    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib Resistant EGFR-Driven Lung Cancer
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    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
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  90. Jan 2024
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    Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
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    SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells
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    MIF modulates p38/ERK phosphorylation via MKP-1 induction in sarcoidosis
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    Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
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    MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet
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    An essential signaling cascade for avian auditory hair cell regeneration
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    B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling
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  103. dx.doi.org dx.doi.org
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    Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers
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    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
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    High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma
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    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
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    TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinome reprogramming is a targetable vulnerability in ESR1 fusion-driven breast cancer
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    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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    Levomilnacipran ameliorates lipopolysaccharide-induced depression-like behaviors and suppressed the TLR4/Ras signaling pathway
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    Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response
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    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
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  167. link.springer.com link.springer.com
    TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice
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