340 Matching Annotations
  1. Nov 2024
  2. www.embopress.org www.embopress.org
    Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
    1
    1. scibot 14 Nov 2024
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      DOI: 10.1038/s44318-024-00290-3

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    embopress.org/doi/10.1038/s44318-024-00290-3
  3. 52.53.155.43 52.53.155.43
    wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html
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    1. scibot 14 Nov 2024
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    52.53.155.43/052dd78e8f9f0d46ee449e71fc9d1d608c537305/wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html
  4. www.sciencedirect.com www.sciencedirect.com
    Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy
    1
    1. scibot 11 Nov 2024
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    sciencedirect.com/science/article/pii/S1535610824003969
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of the Notch signal transducer CSL by Pkc53E-mediated phosphorylation to fend off parasitic immune challenge in Drosophila
    1
    1. scibot 10 Nov 2024
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      DOI: 10.7554/eLife.89582

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    pmc.ncbi.nlm.nih.gov/articles/PMC11540305/
  6. Oct 2024
  7. www.sciencedirect.com www.sciencedirect.com
    CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny
    1
    1. scibot 02 Oct 2024
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      DOI: 10.1016/j.celrep.2024.114797

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    sciencedirect.com/science/article/pii/S2211124724011483
  8. www.sciencedirect.com www.sciencedirect.com
    The TMEM132B-GABAA receptor complex controls alcohol actions in the brain
    2
    1. scibot 02 Oct 2024
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      DOI: 10.1016/j.cell.2024.09.006

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    2. scibot 02 Oct 2024
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    sciencedirect.com/science/article/pii/S0092867424010249
  9. Sep 2024
  10. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 27 Sep 2024
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      DOI: 10.1111/bph.17320

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17320
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.isci.2024.110693

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    ncbi.nlm.nih.gov/pmc/articles/PMC11387596/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multimodal Hox5 activity generates motor neuron diversity
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1038/s42003-024-06835-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11408534/
  13. www.sciencedirect.com www.sciencedirect.com
    Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.celrep.2020.107632

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    sciencedirect.com/science/article/pii/S2211124720305854
  14. elifesciences.org elifesciences.org
    Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
    1
    1. scibot 25 Sep 2024
      RRID:AB_2148465

      DOI: 10.7554/eLife.46043

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      Curator comments: Mouse Anti-Myc-Tag Monoclonal Antibody, Unconjugated, Clone 9B11 Cell Signaling Technology Cat# 2276 also 2276S

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  15. www.sciencedirect.com www.sciencedirect.com
    Primary Cilia Signaling Shapes the Development of Interneuronal Connectivity - ScienceDirect
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.devcel.2017.07.010

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    sciencedirect.com/science/article/pii/S153458071730552X
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrinsic Molecular Proton Sensitivity Underlies GPR4 Effects on Retrotrapezoid Nucleus Neuronal Activation and CO2-Stimulated Breathing
    1
    1. scibot 12 Sep 2024
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      DOI: 10.1523/JNEUROSCI.0799-24.2024

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    ncbi.nlm.nih.gov/pmc/articles/PMC11376338/
  17. www.sciencedirect.com www.sciencedirect.com
    Targeting APT2 improves MAVS palmitoylation and antiviral innate immunity
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.molcel.2024.08.014

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    sciencedirect.com/science/article/pii/S1097276524006683
  18. Aug 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer
    1
    1. scibot 22 Aug 2024
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      DOI: 10.1186/s13046-024-03124-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11321020/
  20. www.sciencedirect.com www.sciencedirect.com
    Genome-wide and cell-type-selective profiling of in vivo small noncoding RNA:target RNA interactions by chimeric RNA sequencing
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.crmeth.2024.100836

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    sciencedirect.com/science/article/pii/S2667237524002091
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1126/science.adk0850

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    ncbi.nlm.nih.gov/pmc/articles/PMC11301400/
  22. www.sciencedirect.com www.sciencedirect.com
    The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response
    1
    1. scibot 20 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114608

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    sciencedirect.com/science/article/pii/S2211124724009586
  23. www.cell.com www.cell.com
    Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation
    1
    1. scibot 13 Aug 2024
      RRID: 331783

      DOI: 10.4414/saez.2012.00493

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    cell.com/cell-reports/fulltext/S2211-1247(24)00493-5
  24. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    Stimulating VAPB-PTPIP51 ER-mitochondria tethering corrects FTD/ALS mutant TDP43 linked Ca2+ and synaptic defects
    1
    1. scibot 02 Aug 2024
      RRID:AB 331,783

      DOI: 10.1186/s40478-024-01742-x

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    actaneurocomms.biomedcentral.com/articles/10.1186/s40478-024-01742-x
  25. Jul 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity
    1
    1. scibot 24 Jul 2024
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      DOI: 10.1016/j.immuni.2024.05.025

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    sciencedirect.com/science/article/pii/S1074761324002796
  27. www.science.org www.science.org
    Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1126/science.adk0850

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    science.org/doi/10.1126/science.adk0850
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
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    1. scibot 18 Jul 2024
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      DOI: 10.1038/s41422-024-00985-6

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    pmc.ncbi.nlm.nih.gov/articles/PMC11442470/
  29. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus
    1
    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101647

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    sciencedirect.com/science/article/pii/S2666379124003616
  30. www.sciencedirect.com www.sciencedirect.com
    Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114448

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    sciencedirect.com/science/article/pii/S2211124724007770
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2020.107695

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    ncbi.nlm.nih.gov/pmc/articles/PMC7262597/
  32. www.sciencedirect.com www.sciencedirect.com
    Chimeric antigen receptor-induced antigen loss protects CD5.CART cells from fratricide without compromising on-target cytotoxicity
    1
    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101628

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    sciencedirect.com/science/article/pii/S266637912400332X
  33. www.sciencedirect.com www.sciencedirect.com
    Synthetic lethal CRISPR screen identifies a cancer cell-intrinsic role of PD-L1 in regulation of vulnerability to ferroptosis
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    sciencedirect.com/science/article/pii/S2211124724008064
  34. www.sciencedirect.com www.sciencedirect.com
    SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration
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  35. www.cell.com www.cell.com
    Sequence variations and accessory proteins adapt TMC functions to distinct sensory modalities
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      DOI: 10.1016/j.neuron.2024.06.013

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    cell.com/neuron/abstract/S0896-6273(24)00448-3
  36. www.cell.com www.cell.com
    Antibody-assisted selective isolation of Purkinje cell nuclei from mouse cerebellar tissue
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    cell.com/cell-reports-methods/abstract/S2667-2375(24)00181-4
  37. Jun 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11209873/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11283362/
  40. elifesciences.org elifesciences.org
    RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia
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      DOI: 10.7554/eLife.88375

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    elifesciences.org/articles/88375
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency in Prader-Willi syndrome gene necdin leads to attenuated cardiac contractility
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    ncbi.nlm.nih.gov/pmc/articles/PMC11144731/
  42. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A comparative analysis of paxillin and Hic-5 proximity interactomes
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      DOI: 10.1002/cm.21878

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    onlinelibrary.wiley.com/doi/10.1002/cm.21878
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
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      DOI: 10.1038/s41467-024-49016-3

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  44. May 2024
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    Functional Analysis of a Novel HNF4A Variant Identified in a Patient with MODY1
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    Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling
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    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
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  50. Apr 2024
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    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
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    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1
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    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
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    Mycobacterial Rv1804c binds to the PEST domain of IκBα and activates macrophage-mediated proinflammatory responses
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    Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion
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    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
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    Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression
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    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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    Bi-allelic variants in CEP295 cause Seckel-like syndrome presenting with primary microcephaly, developmental delay, intellectual disability, short stature, craniofacial and digital abnormalities
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    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
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    ADAMTS-4 enhances oligodendrocyte differentiation and remyelination by cleaving NG2 proteoglycan and attenuating PDGFRα signaling
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    Glucagon-like peptide-1 receptor activation stimulates PKA-mediated phosphorylation of Raptor and this contributes to the weight loss effect of liraglutide
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    Yeast lunapark regulates the formation of trans-Sey1p complexes for homotypic ER membrane fusion
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    Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer
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    TRIM11 attenuates Treg cell differentiation by p62-selective autophagic degradation of AIM2
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    Apical polarity and actomyosin dynamics control Kibra subcellular localization and function in Drosophila Hippo signaling
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    Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis
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    Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
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    Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC
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    RhoB Promotes Salmonella survival by Regulating Autophagy
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    TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma
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    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
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