372 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen
    1
    1. scibot 14 Nov 2024
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      DOI: 10.7554/eLife.89606

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    pmc.ncbi.nlm.nih.gov/articles/PMC11556787/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of the Notch signal transducer CSL by Pkc53E-mediated phosphorylation to fend off parasitic immune challenge in Drosophila
    1
    1. scibot 10 Nov 2024
      RRID:AB_390918

      DOI: 10.7554/eLife.89582

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    pmc.ncbi.nlm.nih.gov/articles/PMC11540305/
  4. Sep 2024
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A biallelic mutation in CACNA2D2 associated with developmental and epileptic encephalopathy affects calcium channel-dependent as well as synaptic functions of α2δ-2
    1
    1. scibot 27 Sep 2024
      RRID:AB_390918

      DOI: 10.1111/jnc.16197

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16197
  6. www.sciencedirect.com www.sciencedirect.com
    Lysosome-related organelle integrity suppresses TIR-1 aggregation to restrain toxic propagation of p38 innate immunity
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114674

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    sciencedirect.com/science/article/pii/S2211124724010258
  7. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 25 Sep 2024
      RRID:AB_2314622

      DOI: 10.1016/j.devcel.2019.04.030

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    sciencedirect.com/science/article/pii/S1534580719303272
  8. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 25 Sep 2024
      RRID:AB_2314622

      DOI: 10.1016/j.cell.2019.01.029

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    sciencedirect.com/science/article/pii/S0092867419300923
  9. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 25 Sep 2024
      RRID:AB_390919

      DOI: 10.1016/j.celrep.2018.12.079

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    sciencedirect.com/science/article/pii/S2211124718320242
  10. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Adult‐specific insulin‐producing neurons in Drosophila melanogaster
    1
    1. scibot 17 Sep 2024
      AB_390918

      DOI: 10.1002/cne.24410

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24410
  11. www.cell.com www.cell.com
    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
    1
    1. scibot 12 Sep 2024
      AB_390918

      DOI: 10.1016/j.cell.2024.08.020

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    cell.com/cell/fulltext/S0092-8674(24)00911-5
  12. www.sciencedirect.com www.sciencedirect.com
    TGF-β and RAS jointly unmask primed enhancers to drive metastasis
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.014

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    sciencedirect.com/science/article/pii/S009286742400905X
  13. Aug 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockout of the orphan membrane transporter Slc22a23 leads to a lean and hyperactive phenotype with a small hippocampal volume
    1
    1. scibot 30 Aug 2024
      RRID:AB_390918

      DOI: 10.1371/journal.pone.0309461

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    ncbi.nlm.nih.gov/pmc/articles/PMC11356391/
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    Opposing GPCR signaling programs protein intake setpoint in Drosophila
    1
    1. scibot 28 Aug 2024
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      DOI: 10.1016/j.cell.2024.07.047

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    sciencedirect.com/science/article/pii/S0092867424008419
  16. www.sciencedirect.com www.sciencedirect.com
    Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration
    1
    1. scibot 23 Aug 2024
      AB_390918

      DOI: 10.1016/j.cell.2024.07.041

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    sciencedirect.com/science/article/pii/S0092867424008353
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small GTPase ActIvitY ANalyzing (SAIYAN) system: A method to detect GTPase activation in living cells
    1
    1. scibot 20 Aug 2024
      RRID:AB_390918

      DOI: 10.1083/jcb.202403179

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    ncbi.nlm.nih.gov/pmc/articles/PMC11303508/
  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mapping chromatic pathways in the Drosophila visual system
    1
    1. scibot 02 Aug 2024
      AB_390918

      DOI: 10.1002/cne.23857

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    onlinelibrary.wiley.com/doi/10.1002/cne.23857/full
  19. Jul 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling
    1
    1. scibot 26 Jul 2024
      RRID:AB_10094468

      DOI: 10.1016/j.celrep.2023.112117

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    ncbi.nlm.nih.gov/pmc/articles/PMC9989824/
  21. www.sciencedirect.com www.sciencedirect.com
    Assembly mechanism of Integrator’s RNA cleavage module
    1
    1. scibot 25 Jul 2024
      AB_390918

      DOI: 10.1016/j.molcel.2024.06.032

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    sciencedirect.com/science/article/pii/S1097276524005392
  22. 52.53.155.43 52.53.155.43
    A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies
    1
    1. scibot 23 Jul 2024
      RRID:AB_390918

      DOI: 10.1111/jnc.14295

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    52.53.155.43/0bf5a35474616f8cd124d354ba59ef8784f885ac/A_dual_role_for_Integrin_64_in_modulat-html.html
  23. www.cell.com www.cell.com
    Stress-dependent condensate formation regulated by the ubiquitin-related modifier Urm1
    1
    1. scibot 23 Jul 2024
      AB_390918

      DOI: 10.1016/j.cell.2024.06.009

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    cell.com/cell/fulltext/S0092-8674(24)00649-4
  24. www.sciencedirect.com www.sciencedirect.com
    Next-generation Drosophila protein interactome map and its functional implications
    1
    1. scibot 19 Jul 2024
      RRID:AB_390918

      DOI: 10.1016/j.devcel.2024.06.002

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    sciencedirect.com/science/article/pii/S1534580724003800
  25. www.sciencedirect.com www.sciencedirect.com
    Astrocytes modulate brain phosphate homeostasis via polarized distribution of phosphate uptake transporter PiT2 and exporter XPR1
    1
    1. scibot 17 Jul 2024
      AB_390918

      DOI: 10.1016/j.neuron.2024.06.020

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    sciencedirect.com/science/article/pii/S0896627324004550
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Specific Isoforms of the Guanine-Nucleotide Exchange Factor dPix Couple Neuromuscular Synapse Growth to Muscle Growth
    1
    1. scibot 16 Jul 2024
      RRID:AB_390918

      DOI: 10.1016/j.devcel.2020.05.015

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    ncbi.nlm.nih.gov/pmc/articles/PMC7346284/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Complex representation of taste quality by second-order gustatory neurons in Drosophila
    1
    1. scibot 14 Jul 2024
      RRID:AB_390918

      DOI: 10.1016/j.cub.2022.07.048

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    ncbi.nlm.nih.gov/pmc/articles/PMC9474709/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ankyrin2 is essential for neuronal morphogenesis and long-term courtship memory in Drosophila
    1
    1. scibot 14 Jul 2024
      AB_390918

      DOI: 10.1186/s13041-023-01026-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10186683/
  29. www.cell.com www.cell.com
    Seamless knockins in Drosophila via CRISPR-triggered single-strand annealing
    1
    1. scibot 12 Jul 2024
      RRID:AB_390918

      DOI: 10.1016/j.devcel.2024.06.004

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    cell.com/developmental-cell/fulltext/S1534-5807(24)00383-6
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wnt/β-catenin signaling within multiple cell types dependent upon kramer regulates Drosophila intestinal stem cell proliferation
    1
    1. scibot 06 Jul 2024
      RRID:AB_390918

      DOI: 10.1016/j.isci.2024.110113

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    ncbi.nlm.nih.gov/pmc/articles/PMC11215309/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel requirements for HAP2/GCS1-mediated gamete fusion in Tetrahymena
    1
    1. scibot 03 Jul 2024
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      DOI: 10.1016/j.isci.2024.110146

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    ncbi.nlm.nih.gov/pmc/articles/PMC11187246/
  32. Jun 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Wnt signaling couples G2 phase control with differentiation during hematopoiesis in Drosophila
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.devcel.2024.05.023

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    sciencedirect.com/science/article/pii/S1534580724003411
  34. www.sciencedirect.com www.sciencedirect.com
    Chromatin-associated cohesin turns over extensively and forms new cohesive linkages in Drosophila oocytes during meiotic prophase
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cub.2024.05.034

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    sciencedirect.com/science/article/pii/S0960982224006778
  35. www.biorxiv.org www.biorxiv.org
    DNA-directed termination of mammalian RNA polymerase II
    1
    1. scibot 07 Jun 2024
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      DOI: 10.1101/2024.06.01.596947

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    biorxiv.org/content/10.1101/2024.06.01.596947v1
  36. May 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Axonal endoplasmic reticulum tubules control local translation via P180/RRBP1-mediated ribosome interactions
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.devcel.2024.05.005

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    sciencedirect.com/science/article/pii/S1534580724003228
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    The Cryptosporidium signaling kinase CDPK5 plays an important role in male gametogenesis and parasite virulence
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.celrep.2024.114263

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    sciencedirect.com/science/article/pii/S2211124724005916
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    FACT maintains chromatin architecture and thereby stimulates RNA polymerase II pausing during transcription in vivo
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    1. scibot 30 May 2024
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      DOI: 10.1016/j.molcel.2024.05.003

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    sciencedirect.com/science/article/pii/S1097276524003964
  40. www.sciencedirect.com www.sciencedirect.com
    Compensatory enhancement of input maintains aversive dopaminergic reinforcement in hungry Drosophila
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.neuron.2024.04.035

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    sciencedirect.com/science/article/pii/S0896627324003258
  41. 52.53.155.43 52.53.155.43
    Normal vision and development in mice with low functional expression of Kir7.1 in heterozygosis for a blindness-producing mutation inactivating the channel
    2
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      DOI: 10.1152/ajpcell.00597.2023

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      DOI: 10.1152/ajpcell.00597.2023

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    52.53.155.43/bd61d1b2a0d7fb97134904bc4e5b10b7c5372ed1/vera-et-al-2024-normal-vision-and-development-in-mice-with-low-functional-expression-of-kir7-1-in-heterozygosis-for-a-html.html
  42. www.sciencedirect.com www.sciencedirect.com
    The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells
    1
    1. scibot 24 May 2024
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      DOI: 10.1016/j.devcel.2024.04.019

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    sciencedirect.com/science/article/pii/S1534580724002946
  43. www.sciencedirect.com www.sciencedirect.com
    Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics
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    1. scibot 16 May 2024
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      DOI: 10.1016/j.stem.2024.04.017

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    sciencedirect.com/science/article/pii/S1934590924001449
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists
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    1. scibot 01 May 2024
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      DOI: 10.1101/2024.04.19.590338

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    ncbi.nlm.nih.gov/pmc/articles/PMC11042255/
  45. Apr 2024
  46. www.sciencedirect.com www.sciencedirect.com
    Change in RhoGAP and RhoGEF availability drives transitions in cortical patterning and excitability in Drosophila
    1
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      DOI: 10.1016/j.cub.2024.04.021

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    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
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    Characterization of 35 novel NR5A1/SF-1 variants identified in individuals with atypical sexual development: The SF1next study
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    Protocol to detect OLA1 polyubiquitination by Aurora A in vivo and in vitro
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    Functional genomics identifies N-acetyllactosamine extension of complex N-glycans as a mechanism to evade lysis by natural killer cells
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    Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development
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    Astrocyte-secreted neurocan controls inhibitory synapse formation and function
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    The essential malaria protein PfCyRPA targets glycans to invade erythrocytes
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    VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates
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  56. rupress.org rupress.org
    The Cby3/ciBAR1 complex positions the annulus along the sperm flagellum during spermiogenesis
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C17orf80 binds the mitochondrial genome to promote its replication
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  58. Feb 2024
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    Bidirectional substrate shuttling between the 26S proteasome and the Cdc48 ATPase promotes protein degradation
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    Sustained antidepressant effects of ketamine metabolite involve GABAergic inhibition-mediated molecular dynamics in aPVT glutamatergic neurons
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    Complex formation of immunoglobulin superfamily molecules Side-IV and Beat-IIb regulates synaptic specificity
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    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
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    Profiling of ERBB receptors and downstream pathways reveals selectivity and hidden properties of ERBB4 antagonists
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  64. Jan 2024
  65. www.sciencedirect.com www.sciencedirect.com
    Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome
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    Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration
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    Cytoneme signaling provides essential contributions to mammalian tissue patterning
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  68. Dec 2023
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    The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation
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    Pib2 is a cysteine sensor involved in TORC1 activation in Saccharomyces cerevisiae
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    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
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    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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    YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration
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  74. Nov 2023
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    Cytochrome c regulates hyphal morphogenesis by interfering with cAMP-PKA signaling in Candida albicans
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    Deep mutational scanning highlights a role for cytosolic regions in Hrd1 function
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    Molecular symmetry breaking in the Frizzled-dependent planar polarity pathway
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    Comparative spatial proteomics of Plasmodium-infected erythrocytes
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
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    A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease
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    Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidation
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    Visualizing the chaperone-mediated folding trajectory of the G protein β5 β-propeller
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    Dual agonistic and antagonistic roles of ZC3H18 provide for co-activation of distinct nuclear RNA decay pathways
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    Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery
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    Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome
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    Metabolism of glucose activates TORC1 through multiple mechanisms in Saccharomyces cerevisiae
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    High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription
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  90. Sep 2023
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    Shared GABA transmission pathology in dopamine agonist- and antagonist-induced dyskinesia
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
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    Nuclear transport receptor KA120 regulates molecular condensation of MAC3 to coordinate plant immune activation
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    A co-opted endogenous retroviral envelope promotes cell survival by controlling CTR1-mediated copper transport and homeostasis
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    Taok1 haploinsufficiency leads to autistic-like behaviors in mice via the dorsal raphe nucleus
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  96. Aug 2023
  97. rupress.org rupress.org
    Presynapses contain distinct actin nanostructures
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  98. www.science.org www.science.org
    A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
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    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cofilin overactivation improves hippocampus-dependent short-term memory
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors
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    E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response
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  103. 52.53.155.43 52.53.155.43
    Re-examining the role of the dorsal fan-shaped body in promoting sleep in Drosophila
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  104. www.sciencedirect.com www.sciencedirect.com
    S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus
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  105. www.sciencedirect.com www.sciencedirect.com
    Exosomal release of the virus-encoded chemokine receptor US28 contributes to chemokine scavenging
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone variants shape chromatin states in Arabidopsis
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  107. Jul 2023
  108. www.sciencedirect.com www.sciencedirect.com
    Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation
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  109. www.sciencedirect.com www.sciencedirect.com
    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
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    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
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  111. Jun 2023
  112. www.sciencedirect.com www.sciencedirect.com
    Convergence of multiple RNA-silencing pathways on GW182/TNRC6
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    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
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    Docking and stability defects in mitofusin highlight the proteasome as a potential therapeutic target
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    ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation
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  116. www.sciencedirect.com www.sciencedirect.com
    A restrictor complex of ZC3H4, WDR82, and ARS2 integrates with PNUTS to control unproductive transcription
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  117. www.jneurosci.org www.jneurosci.org
    A unique role for Protocadherin γC3 in promoting dendrite arborization through an Axin1-dependent mechanism
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  118. May 2023
  119. www.sciencedirect.com www.sciencedirect.com
    Metamorphic proteins at the basis of human autophagy initiation and lipid transfer
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila Tachykininergic Neurons Modulate the Activity of Two Groups of Receptor-Expressing Neurons to Regulate Aggressive Tone
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  121. www.sciencedirect.com www.sciencedirect.com
    Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21
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    Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development
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    Ubiquitin proteomics identifies RNA polymerase I as a target of the Smc5/6 complex
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    TIM23 facilitates PINK1 activation by safeguarding against OMA1-mediated degradation in damaged mitochondria
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    The NFAT3/RERG Complex in Luminal Breast Cancers Is Required to Inhibit Cell Invasion and May Be Correlated With an Absence of Axillary Lymph Nodes Colonization
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal Adenosine A1 Receptor is Critical for Olfactory Function but Unable to Attenuate Olfactory Dysfunction in Neuroinflammation
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  127. www.mdpi.com www.mdpi.com
    Alternative Splicing Changes Promoted by NOVA2 Upregulation in Endothelial Cells and Relevance for Gastric Cancer
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      DOI: 10.3390/ijms24098102

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  128. Apr 2023
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nonlytic Quasi-Enveloped Hepatovirus Release Is Facilitated by pX Protein Interaction with the E3 Ubiquitin Ligase ITCH
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  130. www.sciencedirect.com www.sciencedirect.com
    Heterodimerization-dependent secretion of bone morphogenetic proteins in Drosophila
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments
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  132. www.biorxiv.org www.biorxiv.org
    Optineurin provides a mitophagy contact site for TBK1 activation
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  133. Mar 2023
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterisation of the OTU domain deubiquitinase complement of Toxoplasma gondii
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  135. www.sciencedirect.com www.sciencedirect.com
    Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cell
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    An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay
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    Interaction between PI3K and the VDAC2 channel tethers Ras-PI3K-positive endosomes to mitochondria and promotes endosome maturation
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    Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction
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    A pair of readers of bivalent chromatin mediate formation of Polycomb-based “memory of cold” in plants
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    Therapeutic potency of compound RMY-205 for pulmonary fibrosis induced by SARS-CoV-2 nucleocapsid protein
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    Choroid plexus-targeted NKCC1 overexpression to treat post-hemorrhagic hydrocephalus
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    Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis
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  143. Feb 2023
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    Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling
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    Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m3C modification
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    Mycobacterium abscessus alkyl hydroperoxide reductase C promotes cell invasion by binding to tetraspanin CD81
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    GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes
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    A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite
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  150. Jan 2023
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    Single-copy locus proteomics of early- and late-firing DNA replication origins identifies a role of Ask1/DASH complex in replication timing control
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    Dynamics of CLIMP-63 S-acylation control ER morphology
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    A mitochondrion-free eukaryote contains proteins capable of import into an exogenous mitochondrion-related organelle
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    Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy
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    PPARγ and C/EBPα response to acute cold stress in brown adipose tissue
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  156. Dec 2022
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    The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model
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    Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method
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    R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization
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  161. Nov 2022
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    Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL
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    Ptp61F integrates Hippo, TOR, and actomyosin pathways to control three-dimensional organ size
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    Reduced mitochondria provide an essential function for the cytosolic methionine cycle
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    Nonlytic Quasi-Enveloped Hepatovirus Release Is Facilitated by pX Protein Interaction with the E3 Ubiquitin Ligase ITCH
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  166. Oct 2022
  167. elifesciences.org elifesciences.org
    A network of cytosolic (co)chaperones promotes the biogenesis of mitochondrial signal-anchored outer membrane proteins
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    Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes
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  169. Sep 2022
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    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
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    Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo
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    Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding
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  174. Aug 2022
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    PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis
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    Complex representation of taste quality by second-order gustatory neurons in Drosophila
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    Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes
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  178. Jul 2022
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    Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
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  180. Jun 2022
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    Single unit analysis and wide-field imaging reveal alterations in excitatory and inhibitory neurons in glioma
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    Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes
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    Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses
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  184. www.sciencedirect.com www.sciencedirect.com
    The type V myosin-containing complex HUM is a RAB11 effector powering movement of secretory vesicles
    1
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    Active APPL1 sequestration by Plasmodium favors liver-stage development
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  186. May 2022
  187. www.sciencedirect.com www.sciencedirect.com
    A versatile viral toolkit for functional discovery in the nervous system
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      DOI: 10.1016/j.crmeth.2022.100225

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    TIR domains of plant immune receptors are 2′,3′-cAMP/cGMP synthetases mediating cell death
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      DOI: 10.1016/j.cell.2022.04.032

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  189. elifesciences.org elifesciences.org
    MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
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    Hunchback activates Bicoid in Pair1 neurons to regulate synapse number and locomotor circuit function
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  191. Apr 2022
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    Plasma membrane H+-ATPases promote TORC1 activation in plant suspension cells
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    Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors
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  194. Mar 2022
  195. www.embopress.org www.embopress.org
    K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation
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  196. www.sciencedirect.com www.sciencedirect.com
    Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression
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    Glycopeptidolipid glycosylation controls surface properties and pathogenicity in Mycobacterium abscessus
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  198. www.nature.com www.nature.com
    RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin
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      DOI: 10.1038/s41467-022-28952-y

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  199. elifesciences.org elifesciences.org
    The E3 ubiquitin ligase mindbomb1 controls planar cell polarity-dependent convergent extension movements during zebrafish gastrulation
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  200. www.sciencedirect.com www.sciencedirect.com
    SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport
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  202. www.sciencedirect.com www.sciencedirect.com
    Biotin controls intestinal stem cell mitosis and host-microbiome interactions
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    Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses
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      DOI: 10.1016/j.immuni.2022.02.005

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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANKRD24 organizes TRIOBP to reinforce stereocilia insertion points
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  205. Feb 2022
  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prickle isoform participation in distinct polarization events in the Drosophila eye
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  207. www.sciencedirect.com www.sciencedirect.com
    Spatial regulation of coordinated excitatory and inhibitory synaptic plasticity at dendritic synapses
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  208. Jan 2022
  209. www.molbiolcell.org www.molbiolcell.org
    Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport
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  210. Dec 2021
  211. www.sciencedirect.com www.sciencedirect.com
    Dynamic stem cell selection safeguards the genomic integrity of the epidermis
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  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation
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  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation
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  214. www.sciencedirect.com www.sciencedirect.com
    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
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    The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics
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  216. Nov 2021
  217. www.sciencedirect.com www.sciencedirect.com
    PNET2 is a component of the plant nuclear lamina and is required for proper genome organization and activity
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  218. www.sciencedirect.com www.sciencedirect.com
    Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
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    MAR1 links membrane adhesion to membrane merger during cell-cell fusion in Chlamydomonas
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  220. www.sciencedirect.com www.sciencedirect.com
    Structural mechanism for regulation of Rab7 by site-specific monoubiquitination
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  221. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Divergent acyl carrier protein decouples mitochondrial Fe-S cluster biogenesis from fatty acid synthesis in malaria parasites
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  222. Oct 2021
  223. www.embopress.org www.embopress.org
    Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
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      DOI: 10.15252/embr.202052254

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  224. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activity-dependent modulation of synapse-regulating genes in astrocytes
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  225. www.jneurosci.org www.jneurosci.org
    Axonal CB1 receptors mediate inhibitory bouton formation via cAMP increase and PKA
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      DOI: 10.1523/JNEUROSCI.0851-21.2021

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  226. www.sciencedirect.com www.sciencedirect.com
    S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity
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  227. Sep 2021
  228. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual expression of Atoh1 and Ikzf2 promotes transformation of adult cochlear supporting cells into outer hair cells
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    Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo
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