332 Matching Annotations
  1. Last 7 days
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    Profound synthetic lethality between SMARCAL1 and FANCM
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    sciencedirect.com/science/article/pii/S1097276524008566
  3. Nov 2024
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    Acute multi-level response to defective de novo chromatin assembly in S-phase
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    Chromatin protein complexes involved in gene repression in lamina-associated domains
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    pmc.ncbi.nlm.nih.gov/articles/PMC11535540/
  6. Oct 2024
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    Type I IFN drives unconventional IL-1β secretion in lupus monocytes
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    sciencedirect.com/science/article/pii/S1074761324004485
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    Generation of a PARPi-sensitive homozygous BRCA1-methylated OVCAR8 cell line using targeted CRISPR gene editing
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    Protocol for the efficient and inducible generation of CRISPR-Cas9-edited human cortical neurons from the iCas9-iNgn2 hPSCs
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    sciencedirect.com/science/article/pii/S2666166724005173
  10. Sep 2024
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    P53-dependent hypusination of eIF5A affects mitochondrial translation and senescence immune surveillance
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    SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis
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    Atlastin-1 regulates endosomal tubulation and lysosomal proteolysis in human cortical neurons
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    The Ribosome Assembly Factor LSG1 Interacts with Vesicle-Associated Membrane Protein-Associated Proteins (VAPs)
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    1. scibot 28 Sep 2024
      pMDLg/pRRE

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    ncbi.nlm.nih.gov/pmc/articles/PMC11376406/
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    EFFECTS OF ARYL HYDROCARBON RECEPTOR LIGAND TCDD ON HUMAN TROPHOBLAST CELL DEVELOPMENT
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383004/
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    Neuroendocrine Prostate Cancer Drivers SOX2 and BRN2 Confer Differential Responses to Imipridones ONC201, ONC206, and ONC212 in Prostate Cancer Cell Lines
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    CD8α Structural Domains Enhance GUCY2C CAR-T Cell Efficacy
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    Atrial fibrillation variant-to-gene prioritization through cross-ancestry eQTL and single-nucleus multiomic analyses
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    SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers
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    Ligand requirements for immunoreceptor triggering
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    The Proteasome and Cul3-Dependent Protein Ubiquitination Is Required for Gli Protein-Mediated Activation of Gene Expression in the Hedgehog Pathway
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    Exploring the transcriptional cooperation between RUNX2 and its associated elncRNA RAIN
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    Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis
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    CCR2 cooperativity promotes hematopoietic stem cell homing to the bone marrow
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    Cancer cell stiffening via CoQ10 and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer
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    GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer
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    Targeting heterozygous dominant negative variant of KCNA2 using Gapmer antisense oligonucleotides (ASO) for the treatment of drug-resistant epilepsy
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    sciencedirect.com/science/article/pii/S2162253124002038
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    Protocol to identify receptors of secreted proteins through CRISPR-Cas9 whole-genome screening technology
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    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer’s disease
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  31. www.biorxiv.org www.biorxiv.org
    Inseparable/IER3IP1 are essential for cytokinesis in Drosophila neuroblast and human cells
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  32. Aug 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
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    Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS
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    Engineering a “muco‐trapping” ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19
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    ncbi.nlm.nih.gov/pmc/articles/PMC11256170/
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    De Novo Multi-Omics Pathway Analysis Designed for Prior Data Independent Inference of Cell Signaling Pathways
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    Evaluation of DNA minicircles for delivery of adenine and cytosine base editors using activatable gene on “GO” reporter imaging systems
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    The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4
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    Distinctive In Vitro Phenotypes in iPSC-Derived Neurons From Patients With Gain- and Loss-of-Function SCN2A Developmental and Epileptic Encephalopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10883610/
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    Development of KoRV-pseudotyped lentiviral vectors for efficient gene transfer into freshly isolated immune cells
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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis
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    Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role
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    sciencedirect.com/science/article/pii/S1097276524006233
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    Protocol for the application of single-cell damage in murine intestinal organoid models
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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peptidylarginine deiminase 3 modulates response to neratinib in HER2 positive breast cancer
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    Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development
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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EphA3-targeted chimeric antigen receptor T cells are effective in glioma and generate curative memory T cell responses
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    A Novel Luciferase-Based Reporter Gene Technology for Simultaneous Optical and Radionuclide Imaging of Cells
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      pMDLg-RRE

      DOI: 10.3390/ijms25158206

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  48. www.cell.com www.cell.com
    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
    1
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  49. www.cell.com www.cell.com
    Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma
    1
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Safety and feasibility of anti-CD19 CAR T cells expressing inducible IL-7 and CCL19 in patients with relapsed or refractory large B-cell lymphoma
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  54. aacrjournals.org aacrjournals.org
    Targeting RNA exonuclease XRN1 potentiates efficacy of cancer immunotherapy
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  55. www.researchsquare.com www.researchsquare.com
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  56. Jul 2024
  57. www.sciencedirect.com www.sciencedirect.com
    ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
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  58. www.embopress.org www.embopress.org
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
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  61. www.cell.com www.cell.com
    SigmaR1 shapes rough endoplasmic reticulum membrane sheets
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  62. www.cell.com www.cell.com
    Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-Throughput Discovery and Characterization of Viral Transcriptional Effectors in Human Cells
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation and characterization of inducible KRAB-dCas9 iPSCs from primates for cross-species CRISPRi
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  65. Jun 2024
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour-derived Extracellular Vesicle and Particle Reprogramming of Interstitial Macrophages in the Lung Pre-Metastatic Niche Enhances Vascular Permeability and Metastatic Potential
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  67. www.sciencedirect.com www.sciencedirect.com
    STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The epithelial adherens junction component PLEKHA7 regulates ECM remodeling and cell behavior through miRNA-mediated regulation of MMP1 and LOX
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cadherin-11 contributes to the heterogenous and dynamic Wnt-Wnt-β-catenin pathway activation in Ewing sarcoma
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic patterns and clinical implications of oncogenic tyrosine kinase fusions in human cancers
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TPX2 overexpression promotes sensitivity to dasatinib in breast cancer by activating YAP transcriptional signaling
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 editing of synaptic genes in human embryonic stem cells for functional analysis in induced human neurons
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prickle1‐driven basement membrane deposition of the iPSC‐derived embryoid bodies is separable from the establishment of apicobasal polarity
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis
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  75. www.sciencedirect.com www.sciencedirect.com
    The ribotoxic stress response drives UV-mediated cell death
    2
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disease-linked mutations in Munc18-1 deplete synaptic Doc2
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATP6AP2, a regulator of LRP6/β-catenin protein trafficking, promotes Wnt/β-catenin signaling and bone formation in a cell type dependent manner
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models
    1
    1. scibot 03 Jun 2024
      pMDLg/pRRE

      DOI: 10.1172/jci.insight.175462

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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for preclinical evaluation of locoregionally delivered CAR T cells in patient-derived xenograft models of brain tumors
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      plasmid_12251

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  80. May 2024
  81. journals.asm.org journals.asm.org
    The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication
    2
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      RRID:Addgene_12251

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    journals.asm.org/doi/10.1128/mbio.00499-24
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer
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      pMDLg/pRRE

      DOI: 10.3389/fonc.2024.1227151

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    ncbi.nlm.nih.gov/pmc/articles/PMC11097164/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 genome editing of CCR5 combined with C46 HIV-1 fusion inhibitor for cellular resistant to R5 and X4 tropic HIV-1
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  84. link.springer.com link.springer.com
    Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis
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  85. link.springer.com link.springer.com
    Imaging CAR-NK cells targeted to HER2 ovarian cancer with human sodium-iodide symporter-based positron emission tomography
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Hippo kinases control inflammatory Hippo signaling and restrict bacterial infection in phagocytes
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell competition promotes metastatic intestinal cancer through a multistage process
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Method for the Production of Recombinant VSVs with Confirmation of Biological Activity
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFATC2IP is a mediator of SUMO-dependent genome integrity
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
    1
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Influenza Virus Reduces Ubiquitin E3 Ligase MARCH10 Expression to Decrease Ciliary Beat Frequency
    1
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      RRID:Addgene_12251

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  94. Apr 2024
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
    1
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stepwise Stiffening/Softening of and Cell Recovery from Reversibly Formulated Hydrogel Double Networks
    1
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temporal coordination of the transcription factor response to H2O2 stress
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
    1
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MHC class I-dressing is mediated via phosphatidylserine recognition and is enhanced by polyI:C
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IQGAP3 Is an Important Mediator of Skin Inflammatory Diseases
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  101. www.sciencedirect.com www.sciencedirect.com
    Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases
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  102. www.sciencedirect.com www.sciencedirect.com
    Functional sensory circuits built from neurons of two species
    2
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An EBV-related CD4 TCR immunotherapy inhibits tumor growth in an HLA-DP5+ nasopharyngeal cancer mouse model
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone H2A variant H2A.B is enriched in transcriptionally active and replicating HSV-1 lytic chromatin
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      pMDLg-pRRE

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  105. www.sciencedirect.com www.sciencedirect.com
    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    sciencedirect.com/science/article/pii/S2211124724004443
  106. aacrjournals.org aacrjournals.org
    Sarcoma cells secrete hypoxia-modified collagen VI to weaken the lung endothelial barrier and promote metastasis
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    aacrjournals.org/cancerres/article/84/7/977/742043/Sarcoma-Cells-Secrete-Hypoxia-Modified-Collagen-VI
  107. aacrjournals.org aacrjournals.org
    Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors
    1
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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detecting subtle transcriptomic perturbations induced by lncRNAs knock-down in single-cell CRISPRi screening using a new sparse supervised autoencoder neural network
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin signalling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons
    1
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      pMDLg/pRRE

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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Circular RNA as a source of neoantigens for cancer vaccines
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesenchymal glioma stem cells trigger vasectasia—distinct neovascularization process stimulated by extracellular vesicles carrying EGFR
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FcRn regulates antigen presentation in dendritic cells downstream of DEC205-targeted vaccines
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication
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  116. www.sciencedirect.com www.sciencedirect.com
    Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
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  117. Mar 2024
  118. www.sciencedirect.com www.sciencedirect.com
    Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion
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  119. www.sciencedirect.com www.sciencedirect.com
    A gut-derived hormone regulates cholesterol metabolism
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NOTUM-MEDIATED WNT SILENCING DRIVES EXTRAVILLOUS TROPHOBLAST CELL LINEAGE DEVELOPMENT
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered biosensor enables dynamic aspartate measurements in living cells
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2
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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of β-catenin stability
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression
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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Estrogen Receptor Dimerization BRET-Based Biosensors for Screening Estrogenic Endocrine-Disrupting Chemicals
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer
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      plasmid_12251

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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FH variant pathogenicity promotes purine salvage pathway dependence in kidney cancer
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    scAbsolute: measuring single-cell ploidy and replication status
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  129. www.sciencedirect.com www.sciencedirect.com
    Effectiveness of chemical inactivation of infectious liquid biological waste: a randomized sample study of research laboratories in Switzerland
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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination
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      pMDLg/pRRE

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  131. Feb 2024
  132. www.sciencedirect.com www.sciencedirect.com
    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
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      AddgeneCat#12251

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  133. www.sciencedirect.com www.sciencedirect.com
    The proteomic landscape of genotoxic stress-induced micronuclei
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for antibody recognition of the proximal MUC16 ectodomain
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      pMDLg/pRRE

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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenomic analyses identify FOXM1 as a key regulator of anti-tumor immune response in esophageal adenocarcinoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10876663/
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Production of infectious reporter murine norovirus by VP2 trans-complementation
    1
    1. scibot 29 Feb 2024
      pMDLg/pRRE HIV-1

      DOI: 10.1128/jvi.01261-23

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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis
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    1. scibot 29 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878271/
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium
    1
    1. scibot 29 Feb 2024
      pMDLg/pRRE

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879184/
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering an Autonucleolytic Mammalian Suspension Host Cell Line to Reduce DNA Impurity Levels in Serum-Free Lentiviral Process Streams
    1
    1. scibot 29 Feb 2024
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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties
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  141. link.springer.com link.springer.com
    Endothelial lipase variant T111I does not alter inhibition by angiopoietin-like proteins
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined therapy of CAR-IL-15/IL-15Rα-T cells and GLIPR1 knockdown in cancer cells enhanced anti-tumor effect against gastric cancer
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      pMDLg/pRRE

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  143. www.sciencedirect.com www.sciencedirect.com
    Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment
    2
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels
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    1. scibot 15 Feb 2024
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  145. www.biorxiv.org www.biorxiv.org
    PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma
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    biorxiv.org/content/10.1101/2023.12.23.573190v1
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons
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    1. scibot 15 Feb 2024
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  147. cancerci.biomedcentral.com cancerci.biomedcentral.com
    NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route
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  148. www.sciencedirect.com www.sciencedirect.com
    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actin-dependent recruitment of AGO2 to the zonula adherens
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    1. scibot 09 Feb 2024
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  150. journals.plos.org journals.plos.org
    CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis
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  152. www.sciencedirect.com www.sciencedirect.com
    Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3
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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation
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  156. Jan 2024
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RBL2 represses the transcriptional activity of Multicilin to inhibit multiciliogenesis
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICH deficiency limits the progression of MYC-induced B-cell lymphoma
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isolation and Characterization of Neutralizing Monoclonal Antibodies from a Large Panel of Murine Antibodies against RBD of the SARS-CoV-2 Spike Protein
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  160. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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  161. link.springer.com link.springer.com
    Selective gene expression maintains human tRNA anticodon pools during differentiation
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  162. www.sciencedirect.com www.sciencedirect.com
    PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis
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    sciencedirect.com/science/article/pii/S2211124723016558
  163. Dec 2023
  164. www.sciencedirect.com www.sciencedirect.com
    FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration
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    1. scibot 21 Dec 2023
      plasmid_12251

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  165. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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      Addgene Cat: 12251

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  166. www.sciencedirect.com www.sciencedirect.com
    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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  167. link.springer.com link.springer.com
    Rational optimization of a transcription factor activation domain inhibitor
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  168. Nov 2023
  169. www.sciencedirect.com www.sciencedirect.com
    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    1. scibot 28 Nov 2023
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  170. www.sciencedirect.com www.sciencedirect.com
    An integrated in vitro human iPSCs-derived neuron and in vivo animal approach for preclinical screening of anti-seizure compounds
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized peptide nanofibrils as efficient transduction enhancers for in vitro and ex vivo gene transfer
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  172. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 screens unravel miR-3689a-3p regulating sorafenib resistance in hepatocellular carcinoma via suppressing CCS/SOD1-dependent mitochondrial oxidative stress
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  173. Oct 2023
  174. www.sciencedirect.com www.sciencedirect.com
    Regulation of STING activity in DNA sensing by ISG15 modification
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  175. www.sciencedirect.com www.sciencedirect.com
    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma
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  177. www.nature.com www.nature.com
    Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
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  178. Sep 2023
  179. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Insights into product and process related challenges of lentiviral vector bioprocessing
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  180. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive accumulation of non-muscle myosin IIB during mitosis requires its translocation activity
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  181. 52.53.155.43 52.53.155.43
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    52.53.155.43/6d7222f39ce6ff806d6be40a37ce30f7488ce63a/vdad120-html.html
  182. www.biorxiv.org www.biorxiv.org
    TPX2 expression promotes sensitivity to dasatinib in breast cancer by activating the YAP transcriptional signaling
    1
    1. scibot 12 Sep 2023
      Addgene_12251

      DOI: 10.1101/2023.09.04.556165

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    biorxiv.org/content/10.1101/2023.09.04.556165v1
  183. Aug 2023
  184. www.sciencedirect.com www.sciencedirect.com
    Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons
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    1. scibot 30 Aug 2023
      Addgene_12251

      DOI: 10.1016/j.xgen.2023.100399

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    sciencedirect.com/science/article/pii/S2666979X23002136
  185. www.biorxiv.org www.biorxiv.org
    Endothelial Lipase Variant, T111I, Does Not Alter Inhibition by Angiopoietin-like Proteins
    1
    1. scibot 29 Aug 2023
      plasmid_12251

      DOI: 10.1101/2023.08.18.553740

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    biorxiv.org/content/10.1101/2023.08.18.553740v1
  186. www.nature.com www.nature.com
    Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression
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    1. scibot 24 Aug 2023
      plasmid_12251

      DOI: 10.1038/s41596-023-00863-2

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    nature.com/articles/s41596-023-00863-2
  187. www.sciencedirect.com www.sciencedirect.com
    IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function
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    1. scibot 23 Aug 2023
      RRID:Addgene_12251

      DOI: 10.1016/j.celrep.2023.112996

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    sciencedirect.com/science/article/pii/S2211124723010070
  188. 52.53.155.43 52.53.155.43
    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
    3
    1. scibot 12 Aug 2023
      Addgene #12251

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    3. scibot 10 Aug 2023
      RRID:Addgene_12251

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  189. Jul 2023
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early protective effect of a (“pan”) coronavirus vaccine (PanCoVac) in Roborovski dwarf hamsters after single-low dose intranasal administration
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    1. scibot 29 Jul 2023
      RRID:Addgene_12251

      DOI: 10.3389/fimmu.2023.1166765

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    ncbi.nlm.nih.gov/pmc/articles/PMC10372429/
  191. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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    1. scibot 27 Jul 2023
      RRID:Addgene_12251

      DOI: 10.1016/j.cell.2023.06.020

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    sciencedirect.com/science/article/pii/S0092867423006967
  192. www.sciencedirect.com www.sciencedirect.com
    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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    1. scibot 27 Jul 2023
      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S1534580723003313
  193. 52.53.155.43 52.53.155.43
    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    1. scibot 16 Jul 2023
      Plasmid_12251

      DOI: 10.1101/2023.05.10.540298

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    52.53.155.43/bc0eed2683790c341dcd40acf534b132d1de8ed2/2023.05.10.540298.full-html.html
  194. pubs.acs.org pubs.acs.org
    SIRIUS, Ultra-Scintillating Upconversion Breast Implant for Remote Orthotopic Photodynamic Therapy
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    1. scibot 11 Jul 2023
      RRID:Addgene_12251

      DOI: 10.1021/acsnano.3c01916

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    pubs.acs.org/doi/10.1021/acsnano.3c01916
  195. 52.53.155.43 52.53.155.43
    cir-22-0815-html.html
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      RRID:Addgene_12251

      DOI: 10.1158/2326-6066.cir-22-0815

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    52.53.155.43/0c7b493d1804c631a7718bd69d23acbb033c9efb/cir-22-0815-html.html
  196. Jun 2023
  197. www.sciencedirect.com www.sciencedirect.com
    Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth
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    1. scibot 29 Jun 2023
      Plasmid_12251

      DOI: 10.1016/j.celrep.2023.112680

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    sciencedirect.com/science/article/pii/S2211124723006915
  198. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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    1. scibot 28 Jun 2023
      RRID: Addgene_12251

      DOI: 10.1016/j.cell.2023.05.047

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    sciencedirect.com/science/article/pii/S0092867423005986
  199. www.sciencedirect.com www.sciencedirect.com
    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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    1. scibot 23 Jun 2023
      Addgene_12251

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    sciencedirect.com/science/article/pii/S2211124723006794
  200. www.biorxiv.org www.biorxiv.org
    Transcriptional landscape of DTP-DTEP transition reveals DUSP6 as a driver of HER2 inhibitor tolerance via Neuregulin/HER3 axis
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    1. scibot 22 Jun 2023
      addgene_12251

      DOI: 10.1101/2023.06.14.544493

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    biorxiv.org/content/10.1101/2023.06.14.544493v1
  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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      RRID:Addgene_12251

      DOI: 10.1016/j.molcel.2022.12.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLIT2/ROBO1 signaling suppresses mTORC1 for organelle control and bacterial killing
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    1. scibot 17 Jun 2023
      RRID:Addgene_12251

      DOI: 10.26508/lsa.202301964

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    ncbi.nlm.nih.gov/pmc/articles/PMC10264968/
  203. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of the gut microbiota confers cisplatin resistance in epithelial ovarian cancer
    1
    1. scibot 17 Jun 2023
      RRID:Addgene_12251

      DOI: 10.1158/0008-5472.CAN-22-0455

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    ncbi.nlm.nih.gov/pmc/articles/PMC9772178/
  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network
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    1. scibot 14 Jun 2023
      RRID:Addgene_12251

      DOI: 10.1016/j.immuni.2022.10.021

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    ncbi.nlm.nih.gov/pmc/articles/PMC7614333/
  205. May 2023
  206. www.embopress.org www.embopress.org
    Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG-Syt1-SV2 plasma membrane nanocluster for synaptic vesicle entry
    1
    1. scibot 28 May 2023
      RRID:Addgene_12251

      DOI: 10.15252/embj.2022112095

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    embopress.org/doi/10.15252/embj.2022112095
  207. www.sciencedirect.com www.sciencedirect.com
    Actuation of single downstream nodes in growth factor network steers immune cell migration
    1
    1. scibot 24 May 2023
      Plasmid_12251

      DOI: 10.1016/j.devcel.2023.04.019

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    sciencedirect.com/science/article/pii/S1534580723001958
  208. www.sciencedirect.com www.sciencedirect.com
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
    1
    1. scibot 10 May 2023
      RRID: Addgene 12251

      DOI: 10.1016/j.celrep.2023.112484

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    sciencedirect.com/science/article/pii/S2211124723004953
  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A rabies virus–based toolkit for efficient retrograde... : Neural Regeneration Research
    1
    1. scibot 06 May 2023
      Addgene, Cat# 12251

      DOI: 10.4103/1673-5374.358618

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    ncbi.nlm.nih.gov/pmc/articles/PMC10154474/
  210. www.biorxiv.org www.biorxiv.org
    L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
    1
    1. scibot 04 May 2023
      Addgene_12251

      DOI: 10.1101/2023.03.04.531072

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    biorxiv.org/content/10.1101/2023.03.04.531072v1