308 Matching Annotations
  1. Last 7 days
  2. aacrjournals.org aacrjournals.org
    A Peptide-Based PROTAC Degrader of BRCA2 Sensitizes Metastatic Castration-Resistant Prostate Cancer to PARP Inhibition
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    aacrjournals.org/cancerres/article/85/18/3490/764450/A-Peptide-Based-PROTAC-Degrader-of-BRCA2
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    Butyrylated PGAM5-Triggered and GSH-Responsive Cysteine Polymer Nanoparticles for CBL0137 Delivery to Enhance Necroptosis in Prostate Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/adhm.71387
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    Extracellular Domain Shedding of TROP2 Activates EGFR Signaling to Drive Prostate Cancer Metastasis
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    aacrjournals.org/cancerres/article/85/23/4632/767291/Extracellular-Domain-Shedding-of-TROP2-Activates
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70290
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    Extracellular ATP-P2RY2 signaling drives intratumoral prostaglandin E2 accumulation and adaptive resistance to immunotherapy in solid tumors
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    sciencedirect.com/science/article/pii/S1074761326002578
  7. Jun 2026
  8. aacrjournals.org aacrjournals.org
    ZC3H13 Loss Drives Cancer Metastatic Progression by Disrupting m6A RNA Methylation
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    aacrjournals.org/cancerres/article/86/3/622/771927/ZC3H13-Loss-Drives-Cancer-Metastatic-Progression
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    Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer
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    aacrjournals.org/cancerres/article/86/1/236/771157/Targeting-SUV4-20H-Epigenetic-Enzymes-Enhances
  10. aacrjournals.org aacrjournals.org
    Prostate Cancer Cells Secrete PD-1 in Exosomes to Enhance Myeloid-Derived Suppressor Cell Activity and Promote Tumor Immune Evasion
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    aacrjournals.org/cancerres/article/85/18/3435/764454/Prostate-Cancer-Cells-Secrete-PD-1-in-Exosomes-to
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prostatic fibroblast reprogramming by Interleukin-30 activates prostate cancer metastasis programs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13294413/
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    CDC20 promotes prostate cancer progression via modulating c-MYC and PI3K-AKT signaling
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    sciencedirect.com/science/article/pii/S2589004226017840
  13. aacrjournals.org aacrjournals.org
    Human kallikrein 2: A novel lineage-specific surface target in prostate cancer
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    aacrjournals.org/clincancerres/article/31/21/4543/766834/Human-Kallikrein-2-A-Novel-Lineage-Specific
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TMPRSS2-ERG confers resistance of prostate cancer to antiandrogens
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    pmc.ncbi.nlm.nih.gov/articles/PMC13269939/
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    MCCC2 stabilizes LTBP1 via suppressing SMURF1-dependent ubiquitination to drive bone metastasis in prostate cancer
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    nature.com/articles/s41388-026-03843-4
  16. May 2026
  17. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.70357
  18. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    ROS-Responsive Nanobubbles for Dual-Enhanced Ultrasound and Magnetic Resonance Imaging of Tumor Oxidative Stress
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202600071
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70266
  20. aacrjournals.org aacrjournals.org
    A phase I study of hydroxychloroquine and suba-itraconazole in men with biochemical relapse of prostate cancer (HITMAN-PC): dose escalation results
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    aacrjournals.org/cancerrescommun/article/6/3/687/776538/A-Phase-I-Study-of-Hydroxychloroquine-and-Suba
  21. Apr 2026
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Biobank of genetically defined murine prostate cancer tumoroids uncovers oncogenic pathways and drug vulnerabilities driven by PTEN-loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC13106976/
  23. aacrjournals.org aacrjournals.org
    Bone Metastatic Progression of Prostate Cancer is Regulated by TRIM28-LDHA Mediated Metabolism
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    aacrjournals.org/mcr/article/24/2/93/772003/Bone-Metastatic-Progression-of-Prostate-Cancer-Is
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synergistic Treatment of Prostate Cancer and Multiple Myeloma using CD46-Targeted Radioimmunotherapy Antibody–Drug Conjugates
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    pmc.ncbi.nlm.nih.gov/articles/PMC13080322/
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    Proteomic Profiling Reveals How Physiological Media Reshape Cancer Cell Proteomes and Signaling Networks
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    sciencedirect.com/science/article/pii/S1535947626000654
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    An Artificial Antibody-Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515707
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    Large-Scale Quantitative Morphometry of Platelet α-Granules via SIM Super-Resolution Microscopy for Cancer Liquid Biopsy
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.75094
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    Betulinic acid induces lysosome-dependent death in prostate cancer by targeting DDX5
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    sciencedirect.com/science/article/pii/S0944711326003776
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    Androgen Receptor-Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202520109
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    PCSK9 promotes prostate cancer via facilitating intratumoral cholesterol accumulation and enhancing immunosuppressive tumor microenvironment
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    sciencedirect.com/science/article/pii/S2090123226002997
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    Harnessing senolytics and PARP inhibition to expand the antitumor activity of CDK4/6 inhibitors in prostate cancer
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    aacrjournals.org/mct/article/24/12/1959/768323/Harnessing-Senolytics-and-PARP-Inhibition-to
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    Astragaloside IV directly targets PPP1R14B to sensitize prostate cancer to anti-PD-1 immunotherapy by remodeling the CX3CL1/CD8+ T cell axis
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    Serotonin modulates lineage plasticity in neuroendocrine prostate cancer via epigenetic reprogramming
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    aacrjournals.org/cancerdiscovery/article/16/4/760/775565/Serotonin-Modulates-Lineage-Plasticity-in
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    DS-3939a: A TA-MUC1-directed Antibody-Drug Conjugate with Broad Anti-Tumor Activity
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    aacrjournals.org/mct/article/25/1/7/771286/DS-3939a-A-TA-MUC1-Directed-Antibody-Drug
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    Phase Separation of NFIB Suppresses SLC3A2-Mediated Ferroptosis in Castration-Resistant Prostate Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515340
  37. Mar 2026
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Computational Simulation of the Bioactivity of Selected Compounds Derived From the Sapium and Salvias Genera as Anticancer Agents
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    onlinelibrary.wiley.com/doi/full/10.1155/bmri/4962249
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    Overexpression of the ERG oncogene in prostate cancer identifies candidates for PARP inhibitor-based radiosensitization
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    pmc.ncbi.nlm.nih.gov/articles/PMC12987654/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual regulation of CXCR6+CD8+ T cells modulates cytotoxic and exhaustion-associated programs during prostate cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12983932/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KDM5B-driven glucose metabolic reprogramming promotes enzalutamide resistance in prostate cancer via the lactate/hnRNPA1 lactylation/AR-V7 axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12980947/
  42. www.biorxiv.org www.biorxiv.org
    ASPARAGINE-RICH METASTATIC NICHES DRIVE PROSTATE CANCER ORGANOTROPISM BY ENABLING TRANSLATIONAL REWIRING TOWARD N-GLYCOSYLATED PROTEINS
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    biorxiv.org/content/10.64898/2026.02.27.708521v1
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synergistic Efficacy of Gedatolisib and Darolutamide in Prostate Cancer to Overcome Resistance to Androgen-Targeted Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12958000/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Laurdan: Clarifying Photophysics and Advancing the Characterization of Extracellular Vesicles
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    pmc.ncbi.nlm.nih.gov/articles/PMC12965397/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synthesis of Bispecific Conjugates by ADP‐Ribosyl Cyclases
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    pmc.ncbi.nlm.nih.gov/articles/PMC12955874/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sym024 interacts with a unique epitope on the CD73 homodimer, favoring effective bivalent binding to improve anti-PD1 therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12950896/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12936415/
  48. Feb 2026
  49. www.nature.com www.nature.com
    The FOSB-IGFBP5-IGF-1 axis: a novel regulatory pathway that suppresses prostate cancer growth
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    nature.com/articles/s41417-026-01012-z
  50. www.nature.com www.nature.com
    Epigenetic regulation of NDGA and its synergistic inhibition with EZH2 inhibitors in prostate cancer via NRP1
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    nature.com/articles/s41401-026-01754-4
  51. www.sciencedirect.com www.sciencedirect.com
    Genetic loss of CHD1 regulates distinct histone post-translational modifications in the development of castration-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S1476558626000187
  52. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro-Metastatic N-Glycosylation and Predict Prostate Cancer Progression
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202522885
  53. bio-protocol.org bio-protocol.org
    Non-Enzymatic Isolation of Cancer-Associated Fibroblasts From Human Prostate Tumor Explants
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    bio-protocol.org/en/bpdetail
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Multi-Target Anticancer Activity of Justicia betonica L.: Phytochemical Profiling, In Silico Screening, and Preclinical Evaluation
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202502688
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    Intercellular Horizontal Transfer of TXNDC5 mRNA via Extracellular Vesicles Contributes to Tumor-Associated Macrophage-Mediated Prostate Cancer Metastasis
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511052
  56. Jan 2026
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Three-Dimensional Tumor Spheroids Reveal B7-H3 CAR T Cell Infiltration Dynamics and Microenvironment-Induced Functional Reprogramming in Solid Tumors
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    Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations
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    pmc.ncbi.nlm.nih.gov/articles/PMC13019158/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Mixed Cancer-Cell Models Designed to Capture Inter-Patient Tumor Heterogeneity for Accurate Evaluation of Drug Combinations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12785625/
  60. www.mdpi.com www.mdpi.com
    A Novel Quinolone JH62 (E-2-(Tridec-4-en-1-yl)-quinolin-4(1H)-one) from Pseudomonas aeruginosa Exhibits Potent Anticancer Activity
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  61. link.springer.com link.springer.com
    Experimental and theoretical assessment of salvianolic acid B, ellagic acid, and phorbol esters as drug candidates against breast and prostate cancer
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    link.springer.com/article/10.1007/s44371-025-00381-y
  62. Dec 2025
  63. www.tandfonline.com www.tandfonline.com
    A novel biochip-based liquid biopsy for extracellular vesicle RNA detection in prostate cancer
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    tandfonline.com/doi/full/10.1080/15384047.2025.2593744
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    tRF-21LeuTAA Promotes Oxidative Stress by Altering Glutathione Metabolic Enzymes to Support Prostate Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666318/
  65. Nov 2025
  66. www.nature.com www.nature.com
    KBTBD11 loss promotes AKT hyperactivation and therapeutic vulnerability in prostate cancer
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    nature.com/articles/s41388-025-03576-w
  67. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Integrated Analysis of Single-Cell RNA Sequencing and Machine Learning Reveals a T Cell-Specific PANoptosis Signature Predicting Prognosis and Immunotherapy in Prostate Cancer
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    onlinelibrary.wiley.com/doi/full/10.1155/humu/8889021
  68. Oct 2025
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mistletoe Extracts Inhibit Progressive Growth of Prostate Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12523822/
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mechanistic Insights Into METTL1/WDR4-Mediated m7G Modification in Prostate Cancer Progression and Its Potential as a Therapeutic Target
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    onlinelibrary.wiley.com/doi/10.1002/jbt.70546
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Afro-Caribbean Prostate Cancer Model Reveals Ancestry-Specific Drug Vulnerabilities with Therapeutic Implications for Black Patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC12490968/
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    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511349
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated Omics and Multi-Cohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485374/
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Detection of Genome‐Wide IGF‐1R Recruitment to Enhancer and Promoter Regions of Chromatin in Clinical Prostate Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12483945/
  75. Sep 2025
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Colorectal cancer-associated PCBP1 mutations disrupt protein stability in a dominant negative manner
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485831/
  77. www.nature.com www.nature.com
    Induction of ferroptosis in prostate cancer by CCDC719-13 via TRIM21-mediated ubiquitination of SLC7A11
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    nature.com/articles/s41418-025-01580-x
  78. www.nature.com www.nature.com
    KBTBD11 loss promotes AKT hyperactivation and therapeutic vulnerability in prostate cancer
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    nature.com/articles/s41388-025-03576-w
  79. www.sciencedirect.com www.sciencedirect.com
    A smart gene circuit for precise regulation of tumor cell behavior
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    sciencedirect.com/science/article/pii/S2405805X25001577
  80. journals.plos.org journals.plos.org
    A novel sialylation pathway mediated by extracellular vesicles in aggressive prostate cancer
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    journals.plos.org/plosone/article
  81. 52.53.155.43 52.53.155.43
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    bpspubs.onlinelibrary.wiley.com/doi/10.1002/prp2.70173
  83. www.sciencedirect.com www.sciencedirect.com
    Disrupting the interaction between androgen receptor and its coregulator WDR77 delays the growth of treatment-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S221112472501006X
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drug-Repurposing Screen Identifies Thiostrepton as a Novel Regulator of the Tumor Suppressor DAB2IP
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    pmc.ncbi.nlm.nih.gov/articles/PMC12384208/
  85. Aug 2025
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anticancer activity of triterpene glycosides from the sea star Solaster pacificus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322260/
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A PSMA-targeted Tri-specific Killer Engager enhances NK cell cytotoxicity against prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790377/
  89. Jul 2025
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stathmin Serine 16 Phosphorylation Is a Key Regulator of Cell Cycle Progression Without Activating Migration and Invasion In Vitro
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    pmc.ncbi.nlm.nih.gov/articles/PMC12293763/
  91. www.science.org www.science.org
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    science.org/doi/10.1126/sciadv.adu0847
  92. 52.53.155.43 52.53.155.43
    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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  193. Dec 2023
  194. www.sciencedirect.com www.sciencedirect.com
    Phosphoprotein dynamics of interacting T cells and tumor cells by HySic
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  195. www.sciencedirect.com www.sciencedirect.com
    AID-induced CXCL12 upregulation enhances castration-resistant prostate cancer cell metastasis by stabilizing β-catenin expression
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.
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  198. Nov 2023
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    Prostate cancer cell-derived exosomal IL-8 fosters immune evasion by disturbing glucolipid metabolism of CD8+ T cell
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    Concurrent targeting of HDAC and PI3K to overcome phenotypic heterogeneity of castration-resistant and neuroendocrine prostate cancers
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    Inhibition of the Cyclin K-CDK12 complex induces DNA damage and increases the effect of androgen deprivation therapy in prostate cancer
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  202. Oct 2023
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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
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  205. Sep 2023
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    Combined CRISPRi and proteomics screening reveal a cohesin-CTCF-bound allele contributing to increased expression of RUVBL1 and prostate cancer progression
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  207. Aug 2023
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    Promoter Gene Methylation Regulates Clooxygenase-2 Expression in Androgen-Dependent and Independent Prostate Cancer Cells
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    The long transcript of lncRNA TMPO-AS1 promotes bone metastases of prostate cancer by regulating the CSNK2A1/DDX3X complex in Wnt/β-catenin signaling
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  211. Jul 2023
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  213. Jun 2023
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    Direct anti-tumoral effects of sulfated fucans isolated from echinoderms: a possible role of neuropilin-1/β1 integrin endocytosis and focal adhesion kinase (FAK) degradation.
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    Minor intron splicing is critical for survival of lethal prostate cancer
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  217. May 2023
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    CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation
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  222. Apr 2023
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    Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells
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  224. Mar 2023
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    Drug–gene Interaction Screens Coupled to Tumor Data Analyses Identify the Most Clinically Relevant Cancer Vulnerabilities Driving Sensitivity to PARP Inhibition
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    Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer
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  227. Feb 2023
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    Dynamics of CXCR4 positive circulating tumor cells in prostate cancer patients during radiotherapy
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    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
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    PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition
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    science.org/doi/10.1126/sciadv.ade8641