284 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PCDHGB7 inhibits the progression of triple‐negative breast cancer by suppressing XRCC5/MYC‐mediated ribosome biogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405659/
  3. Aug 2025
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    53BP1 regulates p53-E2F7-dependent transcriptional gene repression and participates in the Fanconi anemia pathway
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    sciencedirect.com/science/article/pii/S2211124725009234
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    Building simplified cancer subtyping and prediction models with glycan gene signatures
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    sciencedirect.com/science/article/pii/S2667237525001766
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    Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases
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    sciencedirect.com/science/article/pii/S2211124725008137
  7. Jul 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281688/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chemoresistant tumor cell secretome potentiates immune suppression in triple negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12257726/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Artificial intelligence-driven discovery of YH395A: A novel TGFβR1 inhibitor with potent anti-tumor activity against triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12235933/
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    A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379125003064
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    Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer
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    A Novel B7-H4xCD3 Bispecific T-cell Engager (PF-07260437) Synergizes with Breast Cancer Standard of Care and Immune Checkpoint Therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214883/
  14. Jun 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12174973/
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    Microcurrent stimulation induces cell death in p53-mutant and 5-FU-resistant breast cancer
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    sciencedirect.com/science/article/pii/S0021925825022641
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    Immune targeting of triple-negative breast cancer through a clinically actionable STING agonist-CAR T cell platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281382/
  18. 52.53.155.43 52.53.155.43
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    A novel peptide MIB1-223aa encoded by exosomal circMIB1 from cancer-associated fibroblasts drives triple-negative breast cancer metastasis and stemness via stabilizing MIB1 to activate Notch signaling
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    sciencedirect.com/science/article/pii/S2090123225004333
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The solute carrier superfamily interactome
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    Metastatic breast cancer cells adapt to a soft environment with limited involvement of mechanotransduction
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    sciencedirect.com/science/article/pii/S0014482725002253
  22. May 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    αB-crystallin enhances radioresistance in basal-like breast cancer cells by suppressing caspase-3 activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12092982/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR Screening of Transcribed Super-Enhancers Identifies Drivers of Triple-Negative Breast Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11534545/
  25. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel synthesised STAT3 inhibitor exerts potent anti-tumour activity by inducing lysosome-dependent cell death
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70071
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    Microtubule associated serine/threonine kinase-3 inhibits the malignant phenotype of breast cancer by promoting phosphorylation-mediated ubiquitination degradation of yes-associated protein
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    link.springer.com/article/10.1186/s13058-025-02028-3
  27. 52.53.155.43 52.53.155.43
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  28. Apr 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Potentiating doxorubicin activity through BCL-2 inhibition in p53 wild-type and mutated triple-negative breast cancer
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  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trabectedin Enhances the Antitumor Effects of IL-12 in Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962391/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sulfatase 2 inhibition sensitizes triple-negative breast cancer cells to paclitaxel through augmentation of extracellular ATP
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    pmc.ncbi.nlm.nih.gov/articles/PMC11951697/
  33. Mar 2025
  34. www.sciencedirect.com www.sciencedirect.com
    KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules
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    Amyloidogenesis promotes HSF1 activity enhancing cell survival during breast cancer metastatic colonization
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    Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers
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    Adhesion strength of tumor cells predicts metastatic disease in vivo
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    Combinatorial screen of targeted agents with the PI3K inhibitors inavolisib, alpelisib, duvelisib, and copanlisib in multi-cell type tumor spheroids
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  40. Feb 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy
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    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    Discovery of a sushi domain-containing protein 2-positive phenotype in circulating tumor cells of metastatic breast cancer patients
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    nature.com/articles/s41598-025-87122-4
  45. Jan 2025
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fibroblast growth factor receptor four inhibitor FGF401 improves the efficacy of trastuzumab in FGFR4-overexpressing breast cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35271
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    Inosine monophosphate dehydrogenase 2 (IMPDH2) modulates response to therapy and chemo-resistance in triple negative breast cancer
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    nature.com/articles/s41598-024-85094-5
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    The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells
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  51. Dec 2024
  52. www.cell.com www.cell.com
    MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity
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    cell.com/cell-reports/abstract/S2211-1247(24)01471-2
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    mLumiOpto Is a Mitochondrial-Targeted Gene Therapy for Treating Cancer
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    GABAA receptor π forms channels that stimulate ERK through a G-protein-dependent pathway
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  55. Nov 2024
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MicroRNA-145-5p inhibits the tumorigenesis of breast cancer through SENP2-regulated ubiquitination of ERK2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11584840/
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    Formate promotes invasion and metastasis in reliance on lipid metabolism
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    cell.com/cell-reports/abstract/S2211-1247(23)01045-8
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers
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    Two cooperative lipid binding sites within the pleckstrin homology domain are necessary for AKT binding and stabilization to the plasma membrane
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    sciencedirect.com/science/article/pii/S0969212624004556
  60. www.biorxiv.org www.biorxiv.org
    Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
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    biorxiv.org/content/10.1101/2024.11.07.622456v1
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11555046/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539583/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Breast cancer cells utilize T3 to trigger proliferation through cellular Ca2+ modulation
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  64. Oct 2024
  65. www.sciencedirect.com www.sciencedirect.com
    Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition
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  66. Sep 2024
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    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11378723/
  69. Aug 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetalax (Oxyphenisatin acetate, NSC 59687) and bisacodyl Cause Oncosis in Triple Negative Breast Cancer Cell lines by Poisoning Ion Exchange Membrane Protein TRPM4
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  71. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ALDH1A3 promotes invasion and metastasis in triple-negative breast cancer by regulating the plasminogen activation pathway
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    A Tetravalent Biparatopic Antibody Causes Strong HER2 Internalization and Inhibits Cellular Proliferation
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    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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  76. Jul 2024
  77. www.biorxiv.org www.biorxiv.org
    The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization
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    biorxiv.org/content/10.1101/2024.07.22.604482v1
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    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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    Construction of mirror-image RNA nanostructure for enhanced biostability and drug delivery efficiency
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    biorxiv.org/content/10.1101/2024.07.17.603907v1
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antibody–Drug Conjugate Sacituzumab Govitecan Enables a Sequential TOP1/PARP Inhibitor Therapy Strategy in Patients with Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11247314/
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11190739/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthesis and Characterization of Click Chemical Probes for Single-Cell Resolution Detection of Epichaperomes in Neurodegenerative Disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC11201208/
  85. May 2024
  86. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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  87. www.biorxiv.org www.biorxiv.org
    Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines
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    biorxiv.org/content/10.1101/2024.05.21.589311v1
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    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
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    sciencedirect.com/science/article/pii/S1074761324002309
  89. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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    science.org/doi/10.1126/scisignal.adh4475
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11097164/
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    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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    sciencedirect.com/science/article/pii/S2666379124002441
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bispecific radioimmunoconjugates exploit receptor heterogeneity for positron emission tomography of tumors expressing HER2 and/or EGFR
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    ncbi.nlm.nih.gov/pmc/articles/PMC11070661/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063767/
  94. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Disrupting the interaction between a p53 gain-of-function mutant and the transcriptional co-activator PC4 reverses drug resistance in cancer cells
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14890
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11030525/
  96. Apr 2024
  97. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    Type I interferon regulation by USP18 is a key vulnerability in cancer
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100297/
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    Versican associates with tumour immune phenotype and limits T cell trafficking via chondroitin sulfate
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