504 Matching Annotations
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    Lack of tumor-derived LCN2 sensitizes pancreatic cancer cells to ferroptosis induction
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  3. Sep 2026
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    Targeting PRMT5 inhibitor-induced adaptation in pancreatic cancer with the RBM39 degrader indisulam
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  6. Aug 2026
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    Targeting addiction to HMGB2-driven transcriptional programs in pancreatic cancer
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    Chrysosplenetin-induced TMED3 aggregation triggers unfolded protein response in pancreatic cancer
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    ERO1L induces macrophage infiltration to potentiate KrasG12D and inflammation-induced pancreatic tumorigenesis via oxidative protein folding of CCL2
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    STING agonist profiling by nucleotide library defines structural determinants of cyclic dinucleotide recognition
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    A stress-adaptive lipid kinase axis defines metabolic vulnerabilities in neuroendocrine prostate cancer
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  12. Jul 2026
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    Acquisition of resistance to RAS inhibition is associated with the upregulation of macropinocytosis through both PI3K-dependent and -independent signaling
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    <fc>MicroRNA</fc>‐15a/16 regulate protein metabolism and are associated with clinical outcomes in pancreatic ductal adenocarcinoma
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    CD44 receptor-blocking biomimetic nanoparticles attenuate extracellular matrix stiffness to enhance chemotherapeutic efficacy in pancreatic cancer
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    KRAS-mediated CCDC6 degradation drives xCT upregulation and ferroptosis evasion
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    USP20-Driven Cholesterol Metabolism Links Inflammatory Signaling to Malignancy and Stromal Co-evolution in Pancreatic Cancer
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    Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer
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    Inhibiting Fatty Acid Oxidation Reverses Autophagy-Mediated Acquired Chemotherapy Resistance in Pancreatic Ductal Adenocarcinoma
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    Vertical inhibition of the autophagy pathway impairs growth and enhances sensitivity to mTORC1 inhibition in pancreatic ductal adenocarcinoma
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  22. Jun 2026
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    Optimized Cryoablation and Combinatorial Chemotherapy Overcome Sublethal Survival in Pancreatic Cancer Cells
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    Pyrazolo-quinolinone suppresses epithelial–mesenchymal transition by targeting the CXCR4/NF-κB axis in human pancreatic cancer cells
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  33. May 2026
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    Multiomics and Genomic Alteration Characterization Identifies VDAC1 as a Mitochondrial‐Associated Biomarker in Pancreatic Cancer
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    Lipid Nanoparticle-Encapsulated mRNAs Encoding Tumor-Specific Toxin Proteins Selectively Target Cancer Cells and Stimulate T Cell Infiltration
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  46. Apr 2026
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    The Vitamin D3 Analog Calcipotriol Attenuates Pancreatic Cancer Malignancy via Downregulating Thrombospondin 1 in Pancreatic Stellate Cells
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    Mutant KRAS promotes NF-κB driven CCL20 chemokine expression in pancreatic ductal adenocarcinoma
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    Shaping Tumor Microenvironment by Amplifying the Complement Cascade for Improved Immune Response in Pancreatic Cancer Model
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    The Combination of a BCL-xL PROTAC and an mTOR Inhibitor Sensitizes Pancreatic Ductal Adenocarcinoma to KRASG12D Inhibitor Treatment
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    Lactate Facilitates the Survival and Invasion of Pancreatic Cancer Cells Under Glucose Deprivation
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  65. Mar 2026
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    Targeting PI3Kδ suppresses pancreatic cancer by dual disruption of fibrosis and immune evasion
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    Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk
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    TIPE2 knockdown enhances the anti-tumor efficacy of NKG2D CAR-T cells against pancreatic cancer via activating NF-κb signaling pathway
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    Radiation-Enhanced CD24 Membrane Trafficking via GPI Anchoring Mediates Anti-Tumor Immune Evasion
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    The Effect of AZD5153 on Radiosensitivity in Pancreatic Cancer Cells Through ATM-chk1 Pathway
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    Engineered pistol ribozymes selectively target KRAS G12V with enhanced efficacy by capping modification
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    Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer
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    L-Lactate reprograms tumor-associated macrophages to drive pancreatic cancer progression via BCL3 lactylation
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    biorxiv.org/content/10.64898/2026.03.06.710237v1
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    GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer
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    DPP4 suppresses pancreatic cancer growth by enhancing ferroptosis sensitivity through stabilization of ACSL4
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  77. Feb 2026
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Placing purines in precision medicine: Targeting a metabolic reliance in KRAS-mutant tumors
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    KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
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    KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
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  81. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    An Insulin-Exosome-TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202515606
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    A 3D multi-compartment assembloid to study combined immune cell infiltration and cytotoxicity
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    Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux
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    SERPINA3 mediates liver cancer cells escape from chemotherapy-induced neutrophil extracellular trap killing
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  85. pubs.acs.org pubs.acs.org
    5′-NucA-SMCC-DM1 and 5′-NucA-SPDMV-DM1 are Potent Aptamer–Drug Conjugates against Pancreatic Cancer
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    pubs.acs.org/doi/full/10.1021/acsomega.5c11364
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    Cyclic di-GMP suppresses cancer metastasis by targeting proteasome 26S subunit non-ATPase 3 independently of STING
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    USP20–RAB8A signaling axis restricts pancreatic cancer progression by disrupting GLUT1 vesicular trafficking and inhibiting glucose uptake
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    Interruption of cross-communication pathways alters the immune cell signature of pancreatic cancer and decreases tumor growth
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  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Target-Specific Locked Nucleic Acid Gapmer Decreases Growth and Metastases of Pancreatic Cancer
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