292 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    An EYA3/NF-κB/CCL2 signaling axis suppresses cytotoxic NK cells in the pre-metastatic niche to promote triple negative breast cancer metastasis
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      DOI: 10.1101/2024.07.31.606072

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  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies
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  5. pubs.acs.org pubs.acs.org
    Delivering DNA Aptamers Across the Blood–Brain Barrier Reveals Heterogeneous Decreased ATP in Different Brain Regions of Alzheimer’s Disease Mouse Models
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      DOI: 10.1021/acscentsci.4c00563

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    Customised design of antisense oligonucleotides targeting EGFR driver mutants for personalised treatment of non-small cell lung cancer
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    Spontaneously regenerative corticospinal neurons in mice
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    Crosstalk between butyrate oxidation in colonocyte and butyrate-producing bacteria
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    sciencedirect.com/science/article/pii/S2589004224020789
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    Glioblastoma induces the recruitment and differentiation of dendritic-like “hybrid” neutrophils from skull bone marrow
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    sciencedirect.com/science/article/pii/S1535610824003076
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    Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity
    1
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  11. Aug 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue- and Temporal-Dependent Dynamics of Myeloablation in Response to Gemcitabine Chemotherapy
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    CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes
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    Uncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization
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    Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling
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    Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
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    Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity
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  18. journals.asm.org journals.asm.org
    rAAV expressing a COBRA-designed influenza hemagglutinin generates a protective and durable adaptive immune response with a single dose
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  19. www.cell.com www.cell.com
    Targeted Phage Display-Based Pulmonary Vaccination in Mice and Non-human Primates
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    cell.com/med/fulltext/S2666-6340(20)30022-2
  20. Jul 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
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    Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response
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    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
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  24. Jun 2024
  25. www.sciencedirect.com www.sciencedirect.com
    Intranasal SARS-CoV-2 Omicron variant vaccines elicit humoral and cellular mucosal immunity in female mice
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  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A modified BCG with depletion of enzymes associated with peptidoglycan amidation induces enhanced protection against tuberculosis in mice
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    1. scibot 08 Jun 2024
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      DOI: 10.7554/eLife.89157

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    ncbi.nlm.nih.gov/pmc/articles/PMC11132681/
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    Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule
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  28. www.sciencedirect.com www.sciencedirect.com
    De novo and salvage purine synthesis pathways across tissues and tumors
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    sciencedirect.com/science/article/pii/S0092867424005208
  29. May 2024
  30. www.sciencedirect.com www.sciencedirect.com
    The temporal progression of lung immune remodeling during breast cancer metastasis
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  31. www.sciencedirect.com www.sciencedirect.com
    Tuft cell-derived acetylcholine promotes epithelial chloride secretion and intestinal helminth clearance
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    sciencedirect.com/science/article/pii/S1074761324001444
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    Complementation testing identifies genes mediating effects at quantitative trait loci underlying fear-related behavior
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    1. scibot 07 May 2024
      Strain ID: 000651

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  33. Apr 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Stimulus-dependent differences in cortical versus subcortical contributions to visual detection in mice
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    sciencedirect.com/science/article/pii/S0960982224004019
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993987/
  36. www.jneurosci.org www.jneurosci.org
    GABAergic/Glycinergic and Glutamatergic Neurons Mediate Distinct Neurodevelopmental Phenotypes of STXBP1 Encephalopathy
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    jneurosci.org/content/44/14/e1806232024
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    Effects of dietary iron deficiency or overload on bone: Dietary details matter
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    sciencedirect.com/science/article/pii/S8756328224000814
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defects of renal tubular homeostasis and cystogenesis in the Pkhd1-knockout
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    ncbi.nlm.nih.gov/pmc/articles/PMC10973142/
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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  40. www.biorxiv.org www.biorxiv.org
    PVRL2 Suppresses Anti-tumor Immunity Through PVRIG- and TIGIT-Independent Pathways
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      DOI: 10.1101/2024.01.26.577132

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    biorxiv.org/content/10.1101/2024.01.26.577132v1
  41. www.jneurosci.org www.jneurosci.org
    GABAergic/glycinergic and glutamatergic neurons mediate distinct neurodevelopmental phenotypes of STXBP1 encephalopathy
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    jneurosci.org/content/jneuro/early/2024/02/13/JNEUROSCI.1806-23.2024.full.pdf
  42. Mar 2024
  43. www.sciencedirect.com www.sciencedirect.com
    Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy
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      The Jackson LaboratoryCat#000651

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    sciencedirect.com/science/article/pii/S1535610824000801
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951988/
  45. www.sciencedirect.com www.sciencedirect.com
    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
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      DOI: 10.1016/j.neuron.2024.02.017

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    2. scibot 21 Mar 2024
      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.neuron.2024.02.017

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  46. www.biorxiv.org www.biorxiv.org
    Lack of TGFβ signaling competency predicts conversion of immune poor cancer to immune rich and response to checkpoint blockade
    1
    1. scibot 15 Mar 2024
      RRID:IMSF_JAX:000651

      DOI: 10.1101/2024.03.06.583752

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    biorxiv.org/content/10.1101/2024.03.06.583752v1
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Machine learning predictions of T cell antigen specificity from intracellular calcium dynamics
    1
    1. scibot 09 Mar 2024
      RRID:IMSR_JAX:000651

      DOI: 10.1126/sciadv.adk2298

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    ncbi.nlm.nih.gov/pmc/articles/PMC10917351/
  48. Feb 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dendritic Cells Overcome Cre/Lox Induced Gene Deficiency by Siphoning Cytosolic Material from Surrounding Cells
    1
    1. scibot 28 Feb 2024
      The Jackson LaboratoryStock# 000651

      DOI: 10.1016/j.isci.2024.109119

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879714/
  50. www.sciencedirect.com www.sciencedirect.com
    Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety
    1
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.immuni.2024.01.018

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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unique immune profiles in Collaborative Cross mice linked to survival and viral clearance upon infection.
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.isci.2024.109103

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  52. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.chembiol.2024.01.002

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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nanosphere pharmacodynamics improves safety of immunostimulatory cytokine therapy
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      The Jackson Laboratory000651

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  54. Jan 2024
  55. www.sciencedirect.com www.sciencedirect.com
    Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
    2
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.ccell.2023.12.013

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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Staphylococcus aureus CamS lipoprotein is a repressor of toxin production that shapes host-pathogen interaction
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      RRID:IMSR_JAX:000651

      DOI: 10.1371/journal.pbio.3002451

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  57. www.sciencedirect.com www.sciencedirect.com
    Characterization of immune populations in the tumor microenvironment of diffuse midline glioma orthotopic mouse models by flow cytometry
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    1. scibot 07 Jan 2024
      The Jackson LaboratoryStrain #:000651

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  58. www.sciencedirect.com www.sciencedirect.com
    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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      The Jackson Laboratory000651

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  59. Dec 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Evaluation of murine renal phagocyte-fungal interactions using intravital confocal microscopy and flow cytometry
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      Jackson LaboratoryStock# 000651

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  61. www.sciencedirect.com www.sciencedirect.com
    More time to kill: a longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.isci.2023.108489

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  62. www.sciencedirect.com www.sciencedirect.com
    Immunotherapy targeting B cells and long-lived plasma cells effectively eliminates pre-existing donor-specific allo-antibodies
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      JAX:000651

      DOI: 10.1016/j.xcrm.2023.101336

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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Propylene glycol inactivates respiratory viruses and prevents airborne transmission
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      RRID:IMSR_JAX:000651

      DOI: 10.15252/emmm.202317932

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  64. 52.53.155.43 52.53.155.43
    cd-22-1301-html.html
    1
    1. scibot 01 Dec 2023
      RRID:IMSR_JAX000651

      DOI: 10.1158/2159-8290.cd-22-1301

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  65. Nov 2023
  66. www.sciencedirect.com www.sciencedirect.com
    Cytochrome c regulates hyphal morphogenesis by interfering with cAMP-PKA signaling in Candida albicans
    1
    1. scibot 28 Nov 2023
      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.celrep.2023.113473

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  67. www.sciencedirect.com www.sciencedirect.com
    Stabilizing vimentin phosphorylation inhibits stem-like cell properties and metastasis of hybrid epithelial/mesenchymal carcinomas
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.celrep.2023.113470

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    sciencedirect.com/science/article/pii/S2211124723014821
  68. www.sciencedirect.com www.sciencedirect.com
    An engineered immunocytokine with collagen affinity improves the tumor bioavailability, tolerability, and therapeutic efficacy of IL-2
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    1. scibot 22 Nov 2023
      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.xcrm.2023.101289

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  69. www.sciencedirect.com www.sciencedirect.com
    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
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      RRID:IMSR_JAX:000651

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    sciencedirect.com/science/article/pii/S2589004223023854
  70. www.nature.com www.nature.com
    Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis
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      RRID:IMSR_JAX:000651

      DOI: 10.1038/s41556-023-01273-y

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    nature.com/articles/s41556-023-01273-y
  71. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
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    1. scibot 10 Nov 2023
      RRID:IMSR_JAX

      DOI: 10.1016/j.immuni.2023.10.004

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    sciencedirect.com/science/article/pii/S1074761323004442
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer
    1
    1. scibot 03 Nov 2023
      BALBc (Strain #:000651)

      DOI: 10.1158/1535-7163.MCT-23-0303

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    ncbi.nlm.nih.gov/pmc/articles/PMC10618734/
  73. Oct 2023
  74. www.sciencedirect.com www.sciencedirect.com
    Bordetella spp. block eosinophil recruitment to suppress the generation of early mucosal protection
    1
    1. scibot 28 Oct 2023
      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.celrep.2023.113294

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  75. www.sciencedirect.com www.sciencedirect.com
    Single-cell and spatial analyses reveal a tradeoff between murine mammary proliferation and lineage programs associated with endocrine cues
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      RRID:IMSR_JAX:000651

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  76. www.sciencedirect.com www.sciencedirect.com
    Development of novel cytoprotective small compounds inhibiting mitochondria-dependent cell death
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.isci.2023.107916

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    sciencedirect.com/science/article/pii/S2589004223019934
  77. www.cell.com www.cell.com
    Hypereosinophilia causes progressive cardiac pathologies in mice
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      JAX:000651

      DOI: 10.1016/j.isci.2023.107990

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      JAX:000651

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    cell.com/iscience/abstract/S2589-0042(23)02067-9
  78. www.nature.com www.nature.com
    Muscimol inhibits plasma membrane rupture and ninjurin-1 oligomerization during pyroptosis
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    1. scibot 06 Oct 2023
      RRID:IMSR_JAX:000651

      DOI: 10.1038/s42003-023-05354-4

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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy
    1
    1. scibot 06 Oct 2023
      JAX:000651

      DOI: 10.3389/fimmu.2023.1237715

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524267/
  80. Sep 2023
  81. www.sciencedirect.com www.sciencedirect.com
    Hyperpolarization-activated cyclic nucleotide-gated cation channel 3 promotes HCC development in a female-biased manner
    1
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      RRID:IMSR_JAX:000651

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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single cell in vivo optogenetic stimulation by two-photon excitation fluorescence transfer
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    1. scibot 28 Sep 2023
      RRID:IMSR_JAX:000651

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    ncbi.nlm.nih.gov/pmc/articles/PMC10518705/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Active shrinkage protects neurons following axonal transection
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      RRID:IMSR_JAX:000651

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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Surgical Inflammation Alters Immune Response to Intraoperative Photodynamic Therapy
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      RRID:ISMR_JAX:000651

      DOI: 10.1158/2767-9764.CRC-22-0494

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    ncbi.nlm.nih.gov/pmc/articles/PMC10494787/
  85. Aug 2023
  86. 52.53.155.43 52.53.155.43
    Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes
    2
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.celrep.2023.112942

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      DOI: 10.1016/j.celrep.2023.112942

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  87. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Guo-html.html
    1
    1. scibot 16 Aug 2023
      RRID:IMSR_JAX:000651

      DOI: 10.1111/bph.16210

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  88. Jul 2023
  89. www.sciencedirect.com www.sciencedirect.com
    Genetic pathways regulating the longitudinal acquisition of cocaine self-administration in a panel of inbred and recombinant inbred mice
    1
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer
    1
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      DOI: 10.3390/ijms241310870

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  91. www.sciencedirect.com www.sciencedirect.com
    A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity
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  92. www.nature.com www.nature.com
    Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain
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  93. www.sciencedirect.com www.sciencedirect.com
    Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors
    2
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  94. www.sciencedirect.com www.sciencedirect.com
    Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways
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  95. Jun 2023
  96. www.sciencedirect.com www.sciencedirect.com
    Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses
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  97. May 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antidepressant-like activity of a brain penetrant HCN channel inhibitor in mice
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements
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  100. www.sciencedirect.com www.sciencedirect.com
    Competition between skin antimicrobial peptides and commensal bacteria in type 2 inflammation enables survival of S. aureus
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  101. Apr 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses
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  104. www.nature.com www.nature.com
    Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PlGF/FLT-1 deficiency leads to reduced STAT3-C/EBPβ signaling and aberrant polarization in decidual macrophages during early spontaneous abortion
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  106. Mar 2023
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Actionable Targets for Breast Cancer Intervention Using a Diversity Outbred Mouse Model
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    Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer
    1
    1. scibot 10 Mar 2023
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      DOI: 10.1101/2023.02.07.527499

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  110. www.mdpi.com www.mdpi.com
    Lacrimal Gland Epithelial Cells Shape Immune Responses through the Modulation of Inflammasomes and Lipid Metabolism
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    1. scibot 09 Mar 2023
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      DOI: 10.3390/ijms24054309

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  111. Feb 2023
  112. aacrjournals.org aacrjournals.org
    Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells
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      DOI: 10.1158/2159-8290.CD-22-0220

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  113. www.sciencedirect.com www.sciencedirect.com
    Periodontal disease is associated with increased gut colonization of pathogenic Haemophilus parainfluenzae in patients with Crohn’s disease
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation
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  115. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hippocampal RNA sequencing in mice selectively bred for high and low activity
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      DOI: 10.1111/gbb.12832

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  116. www.sciencedirect.com www.sciencedirect.com
    Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells
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  117. Jan 2023
  118. www.sciencedirect.com www.sciencedirect.com
    Galanin receptor 3 - a new pharmacological target in retina degeneration
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    An evolved AAV variant enables efficient genetic engineering of murine T cells
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  120. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phenolic glycolipid-1 of Mycobacterium leprae is involved in human Schwann cell line ST8814 neurotoxic phenotype
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    A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration
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  122. Dec 2022
  123. www.sciencedirect.com www.sciencedirect.com
    Interspecies recombination, not de novo mutation, maintains virulence after β-lactam resistance acquisition in Streptococcus pneumoniae
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    Antibody effector functions are associated with protection from respiratory syncytial virus
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    Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells
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  126. 52.53.155.43 52.53.155.43
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  127. Nov 2022
  128. www.sciencedirect.com www.sciencedirect.com
    Systemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS
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    Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses
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    Ketone Body Augmentation Decreases Methacholine Hyperresponsiveness in Mouse Models of Allergic Asthma
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatial transcriptomics of the lacrimal gland features macrophage activity and epithelium metabolism as key alterations during chronic inflammation
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  132. www.sciencedirect.com www.sciencedirect.com
    Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy
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  133. Oct 2022
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    Two distinct compartments of a ctenophore comb plate provide structural and functional integrity for the motility of giant multicilia
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  135. Sep 2022
  136. www.sciencedirect.com www.sciencedirect.com
    In vivo bioluminescence imaging of granzyme B activity in tumor response to cancer immunotherapy
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      JAX:000651

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    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
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    Human gut microbiota stimulate defined innate immune responses that vary from phylum to strain
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  139. Aug 2022
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema
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      JAX:000651

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    Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival
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    Replenishment of myeloid-derived suppressor cells (MDSCs) overrides CR-mediated protection against tumor growth in a murine model of triple-negative breast cancer
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      RRID:IMSR_JAX:000

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    Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
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    EZH2 T367 phosphorylation activates p38 signaling through lysine methylation to promote breast cancer progression
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    Dual pancreatic adrenergic and dopaminergic signaling as a therapeutic target of bromocriptine
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    Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mammary tumor-derived transplants as breast cancer models to evaluate tumor-immune interactions and therapeutic responses
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    Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment
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  149. Jul 2022
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    “Stripe” transcription factors provide accessibility to co-binding partners in mammalian genomes
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    Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization
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  152. Jun 2022
  153. 52.53.155.43 52.53.155.43
    cd-21-0900-html.html
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      JAX:000651

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    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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  155. May 2022
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Binary outcomes of enhancer activity underlie stable random monoallelic expression
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    Disrupting autorepression circuitry generates “open-loop lethality” to yield escape-resistant antiviral agents
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    Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
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  159. Apr 2022
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    Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche
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      The Jackson LaboratoryStrain #:000651

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    A Zika virus mutation enhances transmission potential and confers escape from protective dengue virus immunity
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  162. aacrjournals.org aacrjournals.org
    mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment
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    Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia
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    aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
  164. Mar 2022
  165. onlinelibrary.wiley.com onlinelibrary.wiley.com
    AMPA receptors modulate the reorganization of F-actin in Bergmann glia cells through the activation of RhoA
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    Spatial CRISPR genomics identifies regulators of the tumor microenvironment
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    Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia
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    Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa
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    The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity
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    Induction of broadly reactive influenza antibodies increases susceptibility to autoimmunity
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway
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  172. Feb 2022
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    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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    Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation
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  175. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction
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  177. Jan 2022
  178. www-sciencedirect-com.libproxy.snu.ac.kr www-sciencedirect-com.libproxy.snu.ac.kr
    Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells
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  179. www.sciencedirect.com www.sciencedirect.com
    Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation
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      DOI: 10.1016/j.celrep.2021.110231

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  180. www.sciencedirect.com www.sciencedirect.com
    Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion
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      JAX:000651

      DOI: 10.1016/j.celrep.2021.110215

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  181. Dec 2021
  182. www.sciencedirect.com www.sciencedirect.com
    GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation
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    sciencedirect.com/science/article/pii/S2211124721016788
  183. www.sciencedirect.com www.sciencedirect.com
    Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease
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  184. www.sciencedirect.com www.sciencedirect.com
    P2X7 receptor is essential for cross-dressing of bone marrow-derived dendritic cells
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted therapy to β3 integrin reduces chemoresistance in breast cancer bone metastases
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      DOI: 10.1158/1535-7163.MCT-20-0931

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  186. www.sciencedirect.com www.sciencedirect.com
    Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I
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  187. Nov 2021
  188. www.sciencedirect.com www.sciencedirect.com
    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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  189. www.sciencedirect.com www.sciencedirect.com
    Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells
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      DOI: 10.1016/j.isci.2021.103347

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  190. www.sciencedirect.com www.sciencedirect.com
    A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors
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  191. www.sciencedirect.com www.sciencedirect.com
    Stabilin receptors clear LPS and control systemic inflammation
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      000651

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  192. www.sciencedirect.com www.sciencedirect.com
    α-Ketoglutarate Inhibits Thrombosis and Inflammation by Prolyl Hydroxylase-2 Mediated Inactivation of Phospho-Akt
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      RRID:IMSR_JAX_000651

      DOI: 10.1016/j.ebiom.2021.103672

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    sciencedirect.com/science/article/pii/S2352396421004667
  193. Oct 2021
  194. www.sciencedirect.com www.sciencedirect.com
    Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections
    1
    1. scibot 30 Oct 2021
      000651

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  195. www.sciencedirect.com www.sciencedirect.com
    Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors
    1
    1. scibot 29 Oct 2021
      RRID:IMSR_JAX:000651

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    sciencedirect.com/science/article/pii/S2451945621004414
  196. www.sciencedirect.com www.sciencedirect.com
    Pan-ebolavirus protective therapy by two multifunctional human antibodies
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    1. scibot 29 Oct 2021
      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.cell.2021.09.035

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  197. www.sciencedirect.com www.sciencedirect.com
    Episymbiotic Saccharibacteria suppresses gingival inflammation and bone loss in mice through host bacterial modulation
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      Stock #000651

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    sciencedirect.com/science/article/pii/S193131282100425X
  198. Sep 2021
  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A method for overcoming plasma protein inhibition of tyrosine kinase inhibitors
    1
    1. scibot 30 Sep 2021
      RRID:IMSR_JAX:000651

      DOI: 10.1158/2643-3230.bcd-20-0119

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    ncbi.nlm.nih.gov/pmc/articles/PMC8478262/
  200. www.sciencedirect.com www.sciencedirect.com
    Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming
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    sciencedirect.com/science/article/pii/S1550413121004216
  201. www.sciencedirect.com www.sciencedirect.com
    Tumor dissociation of highly viable cell suspensions for single-cell omic analyses in mouse models of breast cancer
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    1. scibot 21 Sep 2021
      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.xpro.2021.100841

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    sciencedirect.com/science/article/pii/S2666166721005475
  202. www.sciencedirect.com www.sciencedirect.com
    Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species
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      000651

      DOI: 10.1016/j.cell.2021.08.028

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  203. www.sciencedirect.com www.sciencedirect.com
    Simultaneous targeting of TGF-β/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion
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      JAX:00651

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  204. www.sciencedirect.com www.sciencedirect.com
    Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche
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      RRID:IMSR_JAX:000651

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    sciencedirect.com/science/article/pii/S2211124721011189
  205. Aug 2021
  206. www.sciencedirect.com www.sciencedirect.com
    Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
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      JAX:000651

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  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New GABA modulators protect photoreceptor cells from light-induced degeneration in mouse models
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      RRID:IMSR_JAX:000651

      DOI: 10.1096/fj.201701250R

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  208. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Japanese Encephalitis Virus‐induced let‐7a/b interacted with the NOTCH‐TLR7 pathway in microglia and facilitated neuronal death via caspase activation
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      RRID:IMSR_JAX:000651

      DOI: 10.1111/jnc.14645

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14645
  209. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:IMSR_JAX:000651

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    sciencedirect.com/science/article/pii/S2211124718318102
  210. www.sciencedirect.com www.sciencedirect.com
    Midgut Laterality Is Driven by Hyaluronan on the Right
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.devcel.2018.08.002

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  211. www.sciencedirect.com www.sciencedirect.com
    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.immuni.2017.11.003

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  212. www.sciencedirect.com www.sciencedirect.com
    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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      RRID:IMSR_JAX:000651

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  213. www.sciencedirect.com www.sciencedirect.com
    Antibody interference by a non-neutralizing antibody abrogates humoral protection against Plasmodium yoelii liver stage
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      000651

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  214. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:IMSR_JAX:000651

      DOI: 10.1111/bph.14818

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  215. Jul 2021
  216. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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      RRID:IMSR_JAX:000651

      DOI: 10.1111/jnc.14660

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14660
  217. www.sciencedirect.com www.sciencedirect.com
    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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      JAX:000651

      DOI: 10.1016/j.cell.2018.10.038

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  218. www.sciencedirect.com www.sciencedirect.com
    Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity
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      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.cell.2018.09.042

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  219. www.sciencedirect.com www.sciencedirect.com
    Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells
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      The Jackson LaboratoryCat# 000651

      DOI: 10.1016/j.cell.2019.10.015

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  220. www.sciencedirect.com www.sciencedirect.com
    Adenovirus Vector-Based Vaccines Confer Maternal-Fetal Protection against Zika Virus Challenge in Pregnant IFN-αβR−/− Mice
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      The Jackson LaboratoryCat#000651

      DOI: 10.1016/j.chom.2019.10.001

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  221. www.sciencedirect.com www.sciencedirect.com
    The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis
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      000651

      DOI: 10.1016/j.celrep.2019.06.007

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  222. www.sciencedirect.com www.sciencedirect.com
    Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging
    1
    1. scibot 29 Jul 2021
      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.cell.2018.07.010

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    sciencedirect.com/science/article/pii/S0092867418309048
  223. www.sciencedirect.com www.sciencedirect.com
    Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
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    1. scibot 28 Jul 2021
      000651

      DOI: 10.1016/j.cell.2018.11.013

      Resource: (IMSR Cat# JAX_000651,RRID:IMSR_JAX:000651)

      Curator: @bandrow

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    sciencedirect.com/science/article/pii/S0092867418315058
  224. www.sciencedirect.com www.sciencedirect.com
    Midgut Laterality Is Driven by Hyaluronan on the Right
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    1. scibot 28 Jul 2021
      RRID: IMSR_JAX:000651

      DOI: 10.1016/j.devcel.2018.08.002

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      Curator: @Jmenke

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      RRID:IMSR_JAX:000651 RRIDCUR:Unrecognized
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    sciencedirect.com/science/article/pii/S1534580718306385
  225. www.sciencedirect.com www.sciencedirect.com
    A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus
    1
    1. scibot 28 Jul 2021
      000651

      DOI: 10.1016/j.chom.2018.11.011

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      RRID:IMSR_JAX:000651 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1931312818305936
  226. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ORAI2 modulates store-operated calcium entry and T cell-mediated immunity
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    1. scibot 27 Jul 2021
      000651

      DOI: 10.1038/ncomms14714

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      Curator: @mpairish

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    ncbi.nlm.nih.gov/pmc/articles/PMC5355949/
  227. www.sciencedirect.com www.sciencedirect.com
    Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44
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    1. scibot 27 Jul 2021
      RRID:IMSR_JAX

      DOI: 10.1016/j.immuni.2018.08.013

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    sciencedirect.com/science/article/pii/S1074761318303546
  228. 52.53.155.43 52.53.155.43
    An intranasal vaccine durably protects against SARS-CoV-2 variants in mice
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    1. scibot 23 Jul 2021
      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.celrep.2021.109452

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    52.53.155.43/505882aeea4f51f2790a07d89e9823edcfae5813/pdf-html.html
  229. www.mdpi.com www.mdpi.com
    Assessment of Immunological Potential of Glial Restricted Progenitor Graft In Vivo—Is Immunosuppression Mandatory?
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    1. scibot 20 Jul 2021
      RRID:IMSR_JAX:000651

      DOI: 10.3390/cells10071804

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  230. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge
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    1. scibot 17 Jul 2021
      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.immuni.2021.06.018

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    ncbi.nlm.nih.gov/pmc/articles/PMC8249710/
  231. www.sciencedirect.com www.sciencedirect.com
    GABA-receptive microglia selectively sculpt developing inhibitory circuits
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    1. scibot 07 Jul 2021
      RRID:IMSR_JAX:000651

      DOI: 10.1016/j.cell.2021.06.018

      Resource: (IMSR Cat# JAX_000651,RRID:IMSR_JAX:000651)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:000651

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      RRID:IMSR_JAX:000651
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    sciencedirect.com/science/article/pii/S0092867421007534