10,175 Matching Annotations
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    Hexokinase 1 forms rings that regulate mitochondrial fission during energy stress
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    Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs
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    sciencedirect.com/science/article/pii/S0896627324004525
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    Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus
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    PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies
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    Increased regional activity of a pro-autophagy pathway in schizophrenia as a contributor to sex differences in the disease pathology
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    Synaptic plasticity in human thalamocortical assembloids
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    sciencedirect.com/science/article/pii/S2211124724008325
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    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
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    Cross-modal enhancement of defensive behavior via parabigemino-collicular projections
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    A hypothalamic-amygdala circuit underlying sexually dimorphic aggression
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    Dysregulated lipid metabolism networks modulate T-cell function in people with relapsing-remitting multiple sclerosis
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    Spartin-mediated lipid transfer facilitates lipid droplet turnover
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    Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
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    A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle
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    Social Behavioral Deficits with Loss of Neurofibromin Emerge from Peripheral Chemosensory Neuron Dysfunction
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    Exploratory Tau PET/CT with [11C]PBB3 in Patients with Suspected Alzheimer’s Disease and Frontotemporal Lobar Degeneration: A Pilot Study on Correlation with PET Imaging and Cerebrospinal Fluid Biomarkers
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    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    Identification of z-axis filopodia in growth cones using super-resolution microscopy
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    Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8
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    Suppression of excitatory synaptic transmission in the centrolateral amygdala via presynaptic histamine H3 heteroreceptors
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    Exercise training and cold exposure trigger distinct molecular adaptations to inguinal white adipose tissue
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    Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease
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    Reduction of neuroinflammation and seizures in a mouse model of CLN1 batten disease using the small molecule enzyme mimetic, N-Tert-butyl hydroxylamine
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    Sites of Circadian Clock Neuron Plasticity Mediate Sensory Integration and Entrainment
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    Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function
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    Pulmonary interstitial lesions in pemphigus mouse model: Verifying pemphigus may not be only limited to skin and mucosa
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    Epigenetic Alteration of Smooth Muscle Cells Regulates Endothelin-Dependent Blood Pressure and Hypertensive Arterial Remodeling
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    A miRNA screen procedure identifies garz as an essential factor in adult glia functions and validates Drosophila as a beneficial 3Rs model to study glial functions and GBF1 biology
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    Rapid and robust optogenetic control of gene expression in Drosophila
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    αPD-1 immunotherapy promotes IL-17A production and promotes the formation of acute radiation-induced lung injury
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    Pharmacological HDAC3 inhibition alters memory updating in young and old male mice
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    Disruption of EGF Feedback by Intestinal Tumors and Neighboring Cells in Drosophila
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    Regulation of cell–nanoparticle interactions through mechanobiology
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    Cellular Traction Force Holds the Potential as a Drug Testing Readout for In Vitro Cancer Metastasis
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      DOI: 10.1007/s12195-024-00811-4

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    N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine induces endothelium-dependent hyperpolarization-mediated vasorelaxation via store-operated calcium entry mechanism in healthy and intestinal inflammatory mice
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    Enhanced Antitumor Activity by the Combination of Dasatinib and Selinexor in Chronic Myeloid Leukemia
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    Exposure to a sublethal dose of technical grade flubendiamide hampers angiogenesis in the chicken chorioallantoic membrane
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      DOI: 10.1007/s43188-024-00254-z

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    HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice
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    ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines
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    ABC Efflux Transporters and Solute Carriers in the Early Developing Brain of a Marsupial Monodelphis domestica (South American Gray Short-Tailed Opossum)
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    Drug-induced senescence by aurora kinase inhibitors attenuates innate immune response of macrophages on gastric cancer organoids
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    SREBP-1-mediated lipogenesis confers resistance to ferroptosis and improves endothelial injury
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    Sugar and arginine facilitate oral tolerance by ensuring the functionality of tolerogenic immune cell subsets in the intestine
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  58. Jul 2024
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    Exploring the Therapeutic Potential of β-Hydroxybutyrate (BHB) in Clear Cell Renal Cell Carcinoma: A Journey into Fat Browning, Autophagy, and Tumor Slimming
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    Serotonergic and dopaminergic neurons in the dorsal raphe are differentially altered in a mouse model for parkinsonism
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      DOI: 10.7554/eLife.90278

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    Enhancing hepatoprotective action: oxyberberine amorphous solid dispersion system targeting TLR4
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    CLU (clusterin) and PPARGC1A/PGC1α coordinately control mitophagy and mitochondrial biogenesis for oral cancer cell survival
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    Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC
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    cell.com/iscience/abstract/S2589-0042(24)01357-9
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    Moderate-intensity aerobic exercise training improves CD8+ tumor-infiltrating lymphocytes effector function by reducing mitochondrial loss.
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    cell.com/iscience/abstract/S2589-0042(24)01346-4
  87. www.cell.com www.cell.com
    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Avoiding Alkaline Taste through Ionotropic Receptors
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    Enhanced and Sustained T Cell Activation in Response to Fluid Shear Stress
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  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cdk5 inhibition in the SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis suppresses neurodegeneration and extends survival
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      DOI: 10.1111/jnc.16160

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    Time to traumatic intracranial hematoma evacuation: contemporary standard and room for improvement
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    Sex-Dimorphic Kidney-Brain Connectivity Map of Mice
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    β-Carboline derivatives are potent against Acute Myeloid Leukemia in vitro and in vivo
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    Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer
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    Comparable efficacy of oral bendamustine versus intravenous administration in treating hematologic malignancies
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    The PPP2R1A cancer hotspot mutant p.R183W increases clofarabine resistance in uterine serous carcinoma cells by a gain-of-function mechanism
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    Targeting of C-ROS-1 Activity Using a Controlled Release Carrier to Treat Craniosynostosis in a Preclinical Model of Saethre-Chotzen Syndrome
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      DOI: 10.1155/2024/8863925

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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single missense mutations in Vi capsule synthesis genes confer hypervirulence to Salmonella Typhi
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity
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      DOI: 10.1158/2767-9764.CRC-23-0528

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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers
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      DOI: 10.1093/narcan/zcae028

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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive genomic profiling and therapeutic implications for Taiwanese patients with treatment‐naïve breast cancer
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      DOI: 10.1002/cam4.7384

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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The non-mitotic role of HMMR in regulating the localization of TPX2 and the dynamics of microtubules in neurons
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      DOI: 10.7554/eLife.94547

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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease
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      DOI: 10.7554/eLife.89889

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    Pharmacological Modulation of the Cytosolic Oscillator Affects Glioblastoma Cell Biology
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  107. www.mdpi.com www.mdpi.com
    Arsenic Nanoparticles Trigger Apoptosis via Anoikis Induction in OECM-1 Cells
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      DOI: 10.3390/ijms25126723

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  108. www.biorxiv.org www.biorxiv.org
    Adenine nucleotide translocase 2 silencing promotes metabolic adaptations and anoikis in P19 embryonal carcinoma stem cells
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    biorxiv.org/content/10.1101/2024.06.07.597817v1
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    Short-chain fatty acid valerate reduces voluntary alcohol intake in male mice
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      DOI: 10.1186/s40168-024-01829-6

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    Mapping of afferent and efferent connections of phenylethanolamine N‐methyltransferase‐expressing neurons in the nucleus tractus solitarii
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      DOI: 10.1111/cns.14808

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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Mohawk homeobox gene represents a marker and osteo-inhibitory factor in calvarial suture osteoprogenitor cells
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    Mechanical stimulation-induced purinome priming fosters osteogenic differentiation and osteointegration of mesenchymal stem cells from the bone marrow of post-menopausal women
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    Parental dietary vitamin B12 causes intergenerational growth acceleration and protects offspring from pathogenic microsporidia and bacteria
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    Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer
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    Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
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    Protein-energy restriction-induced lipid metabolism disruption causes stable-to-progressive disease shift in Mycobacterium avium-infected female mice
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    Intergenic risk variant rs56258221 skews the fate of naive CD4+ T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis
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    Insulin and leptin oscillations license food-entrained browning and metabolic flexibility
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    The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies
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      DOI: 10.1016/j.immuni.2024.05.017

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    A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
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    CGG repeats in the human FMR1 gene regulate mRNA localization and cellular stress in developing neurons
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    EYA protein complex is required for Wntless retrograde trafficking from endosomes to Golgi
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    Molecular insights into the activation of Mre11-Rad50 endonuclease activity by Sae2/CtIP
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  124. www.sciencedirect.com www.sciencedirect.com
    Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures
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    IP3R2 regulates apoptosis by Ca2+ transfer through mitochondria-ER contacts in hypoxic photoreceptor injury
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma
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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Inhibition of CBX4/7 Hypersensitises Homologous Recombination-Impaired Cancer to Radiation by Compromising CtIP-Mediated DNA End Resection
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering strain- and age-dependent innate immune responses to SARS-CoV-2 infection in air-liquid-interface cultured nasal epithelia
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal sphingosine-1-phosphate receptor 3 expression within the cerebral vasculature after ischemic stroke
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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gossypetin targets the liver-brain axis to alleviate pre-existing liver fibrosis and hippocampal neuroinflammation in mice
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sildenafil amplifies calcium influx and insulin secretion in pancreatic β cells
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 gain-of-function mutation induces metastasis via Brd4-dependent Csf-1 expression
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    Targeted protein degradation systems to enhance Wnt signaling
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    Serum metabolome analysis in hyperthyroid cats before and after radioactive iodine therapy
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase
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    Rewarding Capacity of Optogenetically Activating a Giant GABAergic Central-Brain Interneuron in Larval Drosophila
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    Long non-coding RNA TUG1 is downregulated in Friedreich’s ataxia
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    Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma
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    Impact of TYMS gene polymorphism on the outcome of methotrexate treatment in a sample of Iraqi rheumatoid arthritis patients – identification of novel single nucleotide polymorphism: Cross-sectional study
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    Spinophilin limits metabotropic glutamate receptor 5 scaffolding to the postsynaptic density and cell type-specifically mediates excessive grooming
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    The human alpha7 nicotinic acetylcholine receptor is a host target for the rabies virus glycoprotein
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunomodulation profile of the biosimilar trastuzumab MYL-1401O in a bioequivalence phase I study
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    G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs
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    A subpopulation of luminal progenitors secretes pleiotrophin to promote angiogenesis and metastasis in inflammatory breast cancer
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    The exonuclease TREX1 constitutes an innate immune checkpoint limiting cGAS/STING-mediated antitumor immunity
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    General anaesthetics reduce acute lymphoblastic leukaemia malignancies in vitro and in vivo via CXCR4 and osteopontin mediated mechanisms
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    Targeting PfProhibitin 2-Hu-Hsp70A1A complex as a unique approach towards malaria vaccine development
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    Wildfire-related smoke inhalation worsens cardiovascular risk in sleep disrupted rats
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  150. 52.53.155.43 52.53.155.43
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    Suppression of tumor cell lactate-generating signaling pathways eradicates murine PTEN/p53-deficient aggressive-variant prostate cancer via macrophage phagocytosis
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    Impact of Aging on the Cardiovascular System: Female C57BL/6N mice are a viable model of aortic aging in women
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  153. www.biorxiv.org www.biorxiv.org
    RESPIRATION DEFECTS LIMIT SERINE SYNTHESIS REQUIRED FOR LUNG CANCER GROWTH AND SURVIVAL
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    <em>Journal of Neuroendocrinology</em> | BSN Journal | Wiley Online Library
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    Neurodegeneration and glial morphological changes are both prevented by TRPM2 inhibition during the progression of a Parkinson's disease mouse model
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  156. aacrjournals.org aacrjournals.org
    Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer
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  157. 52.53.155.43 52.53.155.43
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  158. 52.53.155.43 52.53.155.43
    The matricellular protein CCN3 supports lung endothelial homeostasis and function
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  159. 52.53.155.43 52.53.155.43
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  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GD2-Targeting CAR T-cell Therapy for Patients with GD2+ Medulloblastoma
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stabilizing Tumor-Resident Mast Cells Restores T-Cell Infiltration and Sensitizes Sarcomas to PD-L1 Inhibition
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    Desloratadine ameliorates paclitaxel-induced peripheral neuropathy and hypersensitivity reactions in mice
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    Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
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