316 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.medj.2024.06.002

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    sciencedirect.com/science/article/pii/S2666634024002484
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    Synaptic plasticity in human thalamocortical assembloids
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    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114503

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    sciencedirect.com/science/article/pii/S2211124724008325
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    Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease
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    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.chom.2024.06.013

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    sciencedirect.com/science/article/pii/S1931312824002312
  5. Jul 2024
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ABC Efflux Transporters and Solute Carriers in the Early Developing Brain of a Marsupial Monodelphis domestica (South American Gray Short-Tailed Opossum)
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    1. scibot 12 Jul 2024
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      DOI: 10.1002/cne.25655

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.25655
  7. Jun 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer
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    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cmet.2024.05.013

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    sciencedirect.com/science/article/pii/S155041312400189X
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering strain- and age-dependent innate immune responses to SARS-CoV-2 infection in air-liquid-interface cultured nasal epithelia
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    1. scibot 14 Jun 2024
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      DOI: 10.1016/j.isci.2024.110009

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    ncbi.nlm.nih.gov/pmc/articles/PMC11166695/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long non-coding RNA TUG1 is downregulated in Friedreich’s ataxia
    1
    1. scibot 09 Jun 2024
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      DOI: 10.1093/braincomms/fcae170

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    ncbi.nlm.nih.gov/pmc/articles/PMC11154142/
  11. May 2024
  12. www.biorxiv.org www.biorxiv.org
    Distinct Tumor-TAM Interactions in IDH-Stratified Glioma Microenvironments unveiled by Single-Cell and Spatial Transcriptomics
    1
    1. scibot 31 May 2024
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      DOI: 10.1101/2024.05.23.595505

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    biorxiv.org/content/10.1101/2024.05.23.595505v1
  13. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Modelling atopic dermatitis in healthy human skin for the characterization of topical compounds
    1
    1. scibot 31 May 2024
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      DOI: 10.1111/exd.15099

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    onlinelibrary.wiley.com/doi/10.1111/exd.15099
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improving replicability in single-cell RNA-Seq cell type discovery with Dune
    1
    1. scibot 30 May 2024
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      DOI: 10.1186/s12859-024-05814-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11127396/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects
    1
    1. scibot 24 May 2024
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      DOI: 10.1158/2767-9764.CRC-24-0071

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    ncbi.nlm.nih.gov/pmc/articles/PMC11110724/
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    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
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    1. scibot 23 May 2024
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      DOI: 10.1016/j.celrep.2024.114258

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    sciencedirect.com/science/article/pii/S2211124724005862
  17. www.sciencedirect.com www.sciencedirect.com
    Tuft cell-derived acetylcholine promotes epithelial chloride secretion and intestinal helminth clearance
    1
    1. scibot 14 May 2024
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      DOI: 10.1016/j.immuni.2024.03.023

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    sciencedirect.com/science/article/pii/S1074761324001444
  18. www.cell.com www.cell.com
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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    1. scibot 02 May 2024
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      DOI: 10.1016/j.xgen.2024.100556

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    cell.com/cell-genomics/fulltext/S2666-979X(24)00122-8
  19. Apr 2024
  20. aacrjournals.org aacrjournals.org
    Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis
    1
    1. scibot 19 Apr 2024
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      DOI: 10.1158/0008-5472.CAN-23-1542

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    aacrjournals.org/cancerres/article/84/4/527/734130/Mesothelin-Secretion-by-Pancreatic-Cancer-Cells-Co
  21. Mar 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland
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    1. scibot 27 Mar 2024
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      DOI: 10.7554/eLife.93326

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959526/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptome-informed identification and characterisation of Planococcus citri cis- and trans-isoprenyl diphosphate synthase genes
    1
    1. scibot 27 Mar 2024
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      DOI: 10.1016/j.isci.2024.109441

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960109/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N6-methyladenosine-associated genetic variants in NECTIN2 and HPCAL1 are risk factors for abdominal aortic aneurysm
    1
    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.isci.2024.109419

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    ncbi.nlm.nih.gov/pmc/articles/PMC10952030/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive blood metabolomics profiling of Parkinson’s disease reveals coordinated alterations in xanthine metabolism
    1
    1. scibot 22 Mar 2024
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      DOI: 10.1038/s41531-024-00671-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951366/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress-Induced Inflammation
    1
    1. scibot 17 Mar 2024
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      DOI: 10.1158/0008-5472.CAN-23-1237

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    ncbi.nlm.nih.gov/pmc/articles/PMC10940857/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA methylation-environment interactions in the human genome
    1
    1. scibot 17 Mar 2024
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      DOI: 10.7554/eLife.89371

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942648/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer
    1
    1. scibot 16 Mar 2024
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      DOI: 10.1158/1078-0432.CCR-23-0488

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    ncbi.nlm.nih.gov/pmc/articles/PMC10528687/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulations
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    1. scibot 12 Mar 2024
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      DOI: 10.1038/s41420-024-01885-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920792/
  30. 52.53.155.43 52.53.155.43
    HIV-2 MEDIATED EFFECTS ON TARGET AND BYSTANDER CELLS INDUCE PLASMA PROTEOME REMODELLING
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      RRID:SCR_0109

      DOI: 10.1016/j.isci.2024.109344

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      DOI: 10.1016/j.isci.2024.109344

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    3. scibot 08 Mar 2024
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      DOI: 10.1016/j.isci.2024.109344

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    52.53.155.43/da786418a5084198f16fc997d2c488ca198df32d/1-s2.0-S2589004224005650-main-html.html
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patient derived tumoroids of high grade neuroendocrine neoplasms for more personalized therapies
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    1. scibot 06 Mar 2024
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      DOI: 10.1038/s41698-024-00549-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10907580/
  32. Feb 2024
  33. aacrjournals.org aacrjournals.org
    Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA
    1
    1. scibot 27 Feb 2024
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      DOI: 10.1158/2159-8290.CD-23-0456

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    aacrjournals.org/cancerdiscovery/article/14/1/104/732565/Early-Cancer-Detection-in-Li-Fraumeni-Syndrome
  34. aacrjournals.org aacrjournals.org
    PHF6-altered T-ALL harbor epigenetic repressive switch at bivalent promoters and respond to 5-azacitidine and venetoclax
    1
    1. scibot 24 Feb 2024
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      DOI: 10.1158/1078-0432.CCR-23-2159

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    aacrjournals.org/clincancerres/article/30/1/94/732070/PHF6-altered-T-ALL-Harbor-Epigenetic-Repressive
  35. www.sciencedirect.com www.sciencedirect.com
    An iron rheostat controls hematopoietic stem cell fate
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.stem.2024.01.011

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    sciencedirect.com/science/article/pii/S1934590924000419
  36. link.springer.com link.springer.com
    AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication
    1
    1. scibot 22 Feb 2024
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      DOI: 10.1038/s41416-023-02550-1

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    link.springer.com/article/10.1038/s41416-023-02550-1
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
    1
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      DOI: 10.1158/0008-5472.CAN-23-0539

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527051/
  38. www.sciencedirect.com www.sciencedirect.com
    Specialized replication mechanisms maintain genome stability at human centromeres
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      DOI: 10.1016/j.molcel.2024.01.018

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    sciencedirect.com/science/article/pii/S1097276524000546
  39. link.springer.com link.springer.com
    Stratifying ICIs-responsive tumor microenvironment in HCC: from parsing out immune-hypoxic crosstalk to clinically applicable MRI-radiomics models
    1
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      DOI: 10.1038/s41416-023-02463-z

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    link.springer.com/article/10.1038/s41416-023-02463-z
  40. www.biorxiv.org www.biorxiv.org
    A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer
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      DOI: 10.1101/2023.12.10.570854

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    biorxiv.org/content/10.1101/2023.12.10.570854v1
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling
    1
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      DOI: 10.1016/j.isci.2024.108943

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    ncbi.nlm.nih.gov/pmc/articles/PMC10850750/
  42. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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    1. scibot 08 Feb 2024
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      DOI: 10.1038/s41467-024-45067-8

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    nature.com/articles/s41467-024-45067-8
  43. link.springer.com link.springer.com
    Investigating metabolic dysregulation in serum of triple transgenic Alzheimer’s disease male mice: implications for pathogenesis and potential biomarkers
    1
    1. scibot 07 Feb 2024
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      DOI: 10.1007/s00726-023-03375-1

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    link.springer.com/article/10.1007/s00726-023-03375-1
  44. link.springer.com link.springer.com
    CRISPR/Cas9-mediated deletion of a GA-repeat in human GPM6B leads to disruption of neural cell differentiation from NT2 cells
    1
    1. scibot 01 Feb 2024
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      DOI: 10.1038/s41598-024-52675-3

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    link.springer.com/article/10.1038/s41598-024-52675-3
  45. Jan 2024
  46. link.springer.com link.springer.com
    CRISPR/Cas9-mediated deletion of a GA-repeat in human GPM6B leads to disruption of neural cell differentiation from NT2 cells
    1
    1. scibot 30 Jan 2024
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      DOI: 10.1038/s41598-024-52675-3

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    link.springer.com/article/10.1038/s41598-024-52675-3
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIB3, as a robust prognostic biomarker for HNSC, is associated with poor immune infiltration and cancer cell immune evasion
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    Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA
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    A new genomic framework to categorize pediatric acute myeloid leukemia
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    TDP-43-stratified single-cell proteomics of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis
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    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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  52. Dec 2023
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    High Expression of THY1 in Intestinal Gastric Cancer as a Key Factor in Tumor Biology: A Poor Prognosis-Independent Marker Related to the Epithelial–Mesenchymal Transition Profile
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    Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cells
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    Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.
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    Improving replicability in single-cell RNA-Seq cell type discovery with Dune
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  59. Nov 2023
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    Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence
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    Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism
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    The effect of chronic lithium treatment on hippocampal progenitor cells: Transcriptomic analysis and systems pharmacology
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    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
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    Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
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    Comprehensive Analysis of Tumor Microenvironment Reveals Prognostic ceRNA Network Related to Immune Infiltration in Sarcoma
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  67. Sep 2023
  68. www.biorxiv.org www.biorxiv.org
    Long non-coding RNA TUG1 is down-regulated in Friedreich’s ataxia
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    Immune perturbation network identifies an EMT subtype with chromosomal instability and tumor immune-desert microenvironment
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    Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses
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  71. Aug 2023
  72. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature
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    Prognostic and biological function value of OSBPL3 in colorectal cancer analyzed by multi-omic data analysis
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    Effectors Enabling Adaptation to Mitochondrial Complex I Loss in Hürthle Cell Carcinoma
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease
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  79. Jul 2023
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    Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy
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    Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition
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    Prenatal Δ9-tetrahydrocannabinol exposure in males leads to motivational disturbances related to striatal epigenetic dysregulation
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    Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
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    Inter- and intra-tumor heterogeneity of genetic and immune profiles in inherited renal cell carcinoma
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    The diagnostic significance of the ZNF gene family in pancreatic cancer: a bioinformatics and experimental study
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  89. Jun 2023
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    Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    NAD + Metabolism Generates a Metabolic Vulnerability in Endocrine-Resistant Metastatic Breast Tumors in Females
    1
    1. scibot 08 Jun 2023
      RRID:SCR_010943

      DOI: 10.1210/endocr/bqad073

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  94. May 2023
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks
    1
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      DOI: 10.3390/ijms24108717

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  96. www.sciencedirect.com www.sciencedirect.com
    Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy
    1
    1. scibot 24 May 2023
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  97. www.nature.com www.nature.com
    Phenotypic diversity of T cells in human primary and metastatic brain tumors revealed by multiomic interrogation
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    1. scibot 23 May 2023
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      DOI: 10.1038/s43018-023-00566-3

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  98. www.sciencedirect.com www.sciencedirect.com
    Modeling breast cancer proliferation, drug synergies, and alternating therapies
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  99. www.biorxiv.org www.biorxiv.org
    Gene expression genetics of the striatum of Diversity Outbred mice
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      DOI: 10.1101/2023.05.11.540390

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    biorxiv.org/content/10.1101/2023.05.11.540390v1
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models
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  101. www.nature.com www.nature.com
    Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma
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      DOI: 10.1038/s41467-023-38239-5

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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Classification related to immunogenic cell death predicts prognosis, immune microenvironment characteristics, and response to immunotherapy in lower-grade gliomas
    1
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      DOI: 10.3389/fimmu.2023.1102094

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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining basic rules for hardening influenza A virus liquid condensates
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      DOI: 10.7554/eLife.85182

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  104. Apr 2023
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling cross‐talk of RNA modification enzymes reveals tumor microenvironment‐associated clinical significance and immunotherapy prediction in hepatobiliary malignancy
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      DOI: 10.1002/mco2.256

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  106. www.sciencedirect.com www.sciencedirect.com
    Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
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  107. aacrjournals.org aacrjournals.org
    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
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      DOI: 10.1158/2326-6066.CIR-22-0056

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    aacrjournals.org/cancerimmunolres/article/11/3/381/716712/Cancer-Cell-Resistance-to-IFN-Can-Occur-via
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations
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  109. europepmc.org europepmc.org
    A Novel Method for Visualizing In-Vivo Rates of Protein Degradation Provides Insight into how TRIM28 Regulates Muscle Size
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  110. www.sciencedirect.com www.sciencedirect.com
    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
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      DOI: 10.1016/j.celrep.2023.112373

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  111. Mar 2023
  112. www.sciencedirect.com www.sciencedirect.com
    SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive analysis of autophagy-related clusters and individual risk model for immunotherapy response prediction in gastric cancer
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  114. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson’s disease
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  115. www.nature.com www.nature.com
    A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner
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      DOI: 10.1038/s41418-023-01141-0

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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma
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      DOI: 10.1158/2767-9764.CRC-22-0456

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    ncbi.nlm.nih.gov/pmc/articles/PMC9973415/
  117. Feb 2023
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells
    1
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      DOI: 10.21037/tlcr-22-507

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    ncbi.nlm.nih.gov/pmc/articles/PMC9903082/
  119. aacrjournals.org aacrjournals.org
    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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      DOI: 10.1158/0008-5472.CAN-22-1533

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    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
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      DOI: 10.1158/2643-3230.BCD-21-0160

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  121. www.sciencedirect.com www.sciencedirect.com
    Single-cell RNA-seq analysis reveals dual sensing of HIV-1 in blood Axl+ dendritic cells
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      DOI: 10.1016/j.isci.2023.106019

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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1
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      DOI: 10.1158/2767-9764.crc-22-0013

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  123. Jan 2023
  124. www.sciencedirect.com www.sciencedirect.com
    IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome
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      DOI: 10.1016/j.celrep.2022.111883

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    sciencedirect.com/science/article/pii/S221112472201779X
  125. www.sciencedirect.com www.sciencedirect.com
    Enrichment of oral-derived bacteria in inflamed colorectal tumors and distinct associations of Fusobacterium in the mesenchymal subtype
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      DOI: 10.1016/j.xcrm.2023.100920

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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systems level analysis of sex-dependent gene expression changes in Parkinson’s disease
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      DOI: 10.1038/s41531-023-00446-8

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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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      DOI: 10.1158/0008-5472.CAN-21-3217

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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
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      DOI: 10.1158/2159-8290.CD-22-0489

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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy
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      DOI: 10.1158/2159-8290.CD-21-0003

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  130. Dec 2022
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy
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      DOI: 10.1158/1541-7786.MCR-21-0781

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  132. Nov 2022
  133. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    sciencedirect.com/science/article/abs/pii/S1097276522010644
  134. aacrjournals.org aacrjournals.org
    DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1
    1
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      DOI: 10.1158/2767-9764.CRC-22-0013

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    aacrjournals.org/cancerrescommun/article/2/11/1388/710518/DDR2-Coordinates-EMT-and-Metabolic-Reprogramming
  135. link.springer.com link.springer.com
    The LncRNA MIAT is identified as a regulator of stemness-associated transcript in glioma
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      DOI: 10.1007/s11033-022-07962-5

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  136. www.sciencedirect.com www.sciencedirect.com
    Dissecting the genetic and microenvironmental factors of gastric tumorigenesis in mice
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice
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      DOI: 10.1172/JCI158869

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  138. Oct 2022
  139. www.sciencedirect.com www.sciencedirect.com
    Circadian transcriptional pathway atlas highlights a proteasome switch in intermittent fasting
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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2-dependent glutaminolysis pathway
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      DOI: 10.1126/sciadv.abq0117

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  141. alzres.biomedcentral.com alzres.biomedcentral.com
    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
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      DOI: 10.1186/s13195-022-01096-3

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  142. www.science.org www.science.org
    Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2–dependent glutaminolysis pathway
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct biomarker profiles and TCR sequence diversity characterize the response to PD-L1 blockade in a mouse melanoma model
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  144. www.sciencedirect.com www.sciencedirect.com
    A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation
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    sciencedirect.com/science/article/pii/S2666979X22001409
  145. Sep 2022
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biological misinterpretation of transcriptional signatures in tumor samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data
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  147. www.sciencedirect.com www.sciencedirect.com
    A small proportion of X-linked genes contribute to X chromosome upregulation in early embryos via BRD4-mediated transcriptional activation
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  148. www.sciencedirect.com www.sciencedirect.com
    Artificial gravity partially protects space-induced neurological deficits in Drosophila melanogaster
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  149. Aug 2022
  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circulating microRNA: Myocardium-derived prenatal biomarker of ventricular septal defects
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Race-associated molecular changes in gynecologic malignancies
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of CXCL10 and CXCL11 as the candidate genes involving the development of colitis-associated colorectal cancer
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance
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  154. Jun 2022
  155. 52.53.155.43 52.53.155.43
    KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model
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  156. www.sciencedirect.com www.sciencedirect.com
    MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines
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    Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus
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  158. aacrjournals.org aacrjournals.org
    Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
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      DOI: 10.1158/0008-5472.CAN-21-0548

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    aacrjournals.org/cancerres/article/82/11/2141/699099/Phosphorylation-of-SHP2-at-Tyr62-Enables-Acquired
  159. May 2022
  160. www.sciencedirect.com www.sciencedirect.com
    Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment
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  161. www.sciencedirect.com www.sciencedirect.com
    BMAL1 modulates smooth muscle cells phenotypic switch towards fibroblast-like cells and stabilizes atherosclerotic plaques by upregulating YAP1
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  162. aacrjournals.org aacrjournals.org
    Tumor ENPP1(CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
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  163. www.sciencedirect.com www.sciencedirect.com
    Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 module
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  164. Apr 2022
  165. www.sciencedirect.com www.sciencedirect.com
    Sex disparities in influenza: A multiscale network analysis
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  166. www.sciencedirect.com www.sciencedirect.com
    Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches
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  167. aacrjournals.org aacrjournals.org
    Lactate rewires lipid metabolism and sustains a metabolic-epigenetic axis in prostate cancer
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    aacrjournals.org/cancerres/article/82/7/1267/694059/Lactate-Rewires-Lipid-Metabolism-and-Sustains-a
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cells retrace a stepwise differentiation program during malignant progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7611766/
  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tenascin-C can Serve as an Indicator for the Immunosuppressive Microenvironment of Diffuse Low-Grade Gliomas
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  170. Mar 2022
  171. elifesciences.org elifesciences.org
    Novel insights from a multiomics dissection of the Hayflick limit
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      DOI: 10.7554/eLife.70283

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  172. f1000research.com f1000research.com
    Characterizing gene expression in an&nbsp;<i>in vitro</i> biomechanical strain model of joint health
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      DOI: 10.12688/f1000research.109602.1

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  173. aacrjournals.org aacrjournals.org
    Race-associated Molecular Changes in Gynecologic Malignancies
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    aacrjournals.org/cancerrescommun/article/2/2/99/681553/Race-associated-Molecular-Changes-in-Gynecologic
  174. Feb 2022
  175. elifesciences.org elifesciences.org
    FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
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      DOI: 10.7554/eLife.71892

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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model
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      DOI: 10.1016/j.biopsych.2020.05.024

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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mediator of DNA damage checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive lobular carcinoma of the breast
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-Omics Profiling Suggesting Intratumoral Mast Cells as Predictive Index of Breast Cancer Lung Metastasis
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  179. Jan 2022
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy
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      DOI: 10.1038/s41467-021-27869-2

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  181. www.sciencedirect.com www.sciencedirect.com
    Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy
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  182. Dec 2021
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice
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  184. Nov 2021
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interdependence of neural network dysfunction and microglial alterations in Alzheimer’s disease-related models
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  186. www.sciencedirect.com www.sciencedirect.com
    Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition
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  187. Oct 2021
  188. www.sciencedirect.com www.sciencedirect.com
    Establishment of a prognostic model of ten transcription factors in gastric cancer
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  189. www.nature.com www.nature.com
    Single-cell RNA sequencing for the identification of early-stage lung cancer biomarkers from circulating blood
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  190. www.sciencedirect.com www.sciencedirect.com
    Role of miR-2392 in driving SARS-CoV-2 infection
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  191. Sep 2021
  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes
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    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
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    Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia
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  206. Jul 2021
  207. onlinelibrary.wiley.com onlinelibrary.wiley.com
    DNA hypermethylation is associated with invasive phenotype of malignant melanoma
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    The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response
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    The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy
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    PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD
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    Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer’s Disease
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    Inducible and reversible phenotypes in a novel mouse model of Friedreich's Ataxia.
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    Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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    The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging
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    A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling
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    The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice
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    Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain
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    Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging
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    An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis
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  230. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast
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  232. www.frontiersin.org www.frontiersin.org
    Monocytic Ontogeny of Regenerated Macrophages Characterizes the Mesotheliomagenic Responses to Carbon Nanotubes
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    Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape
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    Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin
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