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    Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency
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    Brain-based correlates of depression and traumatic brain injury: a systematic review of structural and functional magnetic resonance imaging studies
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  4. Nov 2024
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    Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation
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    Protumoral lipid droplet–loaded macrophages are enriched in human glioblastoma and can be therapeutically targeted
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  7. Oct 2024
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    Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
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    Pharmacologic inhibition of eIF4A blocks NRF2 synthesis to prevent osteosarcoma metastasis
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    Protocol for the efficient and inducible generation of CRISPR-Cas9-edited human cortical neurons from the iCas9-iNgn2 hPSCs
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    sciencedirect.com/science/article/pii/S2666166724005173
  11. Sep 2024
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    DDI2 protease controls embryonic development and inflammation via TCF11/NRF1
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    sciencedirect.com/science/article/pii/S2589004224021187
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    Redox-dependent condensation and cytoplasmic granulation by human ssDNA-binding protein-1 delineate roles in oxidative stress response
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    sciencedirect.com/science/article/pii/S2589004224020133
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    Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.
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    sciencedirect.com/science/article/pii/S2589004224019266
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    Spontaneously regenerative corticospinal neurons in mice
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  16. Aug 2024
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    Uncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization
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    Phosphoglycerate kinase is a central leverage point in Parkinson’s disease–driven neuronal metabolic deficits
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    Patient-derived tumor organoids mimic treatment-induced DNA damage response in glioblastoma
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    Taste cells expressing Ionotropic Receptor 94e reciprocally impact feeding and egg laying in Drosophila
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    Schwann cell-secreted PGE2 promotes sensory neuron excitability during development
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    Drosophila appear resistant to trans-synaptic tau propagation
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  23. Jul 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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      DOI: 10.1158/2767-9764.CRC-23-0428

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    Pandemic-associated pernio harbors footprints of an abortive SARS-CoV-2 infection
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    Dynamic landscapes and protective immunity coordinated by influenza-specific lung-resident memory CD8+ T cells revealed by intravital imaging
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    The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
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    Respiratory infection with influenza A virus delays remyelination and alters oligodendrocyte metabolism
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    Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
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    Low- and high-grade glioma-associated vascular cells differentially regulate tumor growth
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      DOI: 10.1158/1541-7786.MCR-23-1069

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  31. Jun 2024
  32. www.cell.com www.cell.com
    Moderate-intensity aerobic exercise training improves CD8+ tumor-infiltrating lymphocytes effector function by reducing mitochondrial loss.
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    cell.com/iscience/abstract/S2589-0042(24)01346-4
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    CGG repeats in the human FMR1 gene regulate mRNA localization and cellular stress in developing neurons
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    Targeting PfProhibitin 2-Hu-Hsp70A1A complex as a unique approach towards malaria vaccine development
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    Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule
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  36. May 2024
  37. www.biorxiv.org www.biorxiv.org
    Drosophila appear resistant to trans-synaptic tau propagation
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    A bioinformatic analysis of T-cell epitope diversity in SARS-CoV-2 variants: association with COVID-19 clinical severity in the United States population
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    mcr-23-1069-html.html
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    Variability in cell division among anatomical sites shapes Escherichia coli antibiotic survival in a urinary tract infection mouse model
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    sciencedirect.com/science/article/pii/S1931312824001367
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    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
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      DOI: 10.1016/j.ccell.2024.04.011

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    sciencedirect.com/science/article/pii/S1535610824001351
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    Efficacy of Engraftment and Safety of Human Umbilical Di-Chimeric Cell (HUDC) Therapy after Systemic Intraosseous Administration in an Experimental Model
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      DOI: 10.3390/biomedicines12051064

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    mdpi.com/2227-9059/12/5/1064
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    Tumor-derived extracellular vesicles as a biomarker for breast cancer diagnosis and metastasis monitoring
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    ncbi.nlm.nih.gov/pmc/articles/PMC11075063/
  44. 52.53.155.43 52.53.155.43
    Intercalated amygdala dysfunction drives extinction deficits in the Sapap3 mouse model of obsessive-compulsive disorder
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      DOI: 10.1101/2024.02.12.578709

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    52.53.155.43/6c5cd8384736ce84e391029ae5235195aa87ce0d/2024.02.12.578709v1.full (1)-html.html
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    2024.02.12.578709v1.full-html.html
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    Antigen-level resolution of commensal-specific B cell responses can be enabled by phage display screening coupled with B cell tetramers
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    Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids
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      DOI: 10.1016/j.celrep.2024.114173

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    52.53.155.43/7165d3b920717872e9ecee45ef5f3cb3a7917c57/mmc6-html.html
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    Division of labor for defensive retaliation and preemption by the peripheral and central nervous systems in the nudibranch Berghia
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    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
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    Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue
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    Biodistribution and Safety of Human Multi-Chimeric Cells (HMCC) After Systemic Intraosseous and Intravenous Administration in the Experimental Mouse Model
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    Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites
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    Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
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    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
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    Dual amylin and calcitonin receptor agonist treatment reduces biomarkers associated with kidney fibrosis in diabetic rats
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    Bioluminescence Imaging Reveals Enhanced SARS-CoV-2 Clearance in Mice with Combinatorial Regimens
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    Comparative transcriptomic analysis of bovine mesenchymal stromal cells reveals tissue-source and species-specific differences
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    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    Protein semisynthesis underscores the role of a conserved lysine in activation and desensitization of acid-sensing ion channels
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    Phenobarbital does not worsen outcomes of neonatal hypoxia on hippocampal LTP on rats
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    IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis
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  96. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Blockage of the fractalkine pathway reduces hyperalgesia and prevents morphological glial alterations—Comparison between inflammatory and neuropathic orofacial pain in male rats
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  97. Nov 2023
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    PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
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    A pneumonectomy model to study flow-induced pulmonary hypertension and compensatory lung growth
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Title: Regional variation in the organization and connectivity of the first synapse in the primate night vision pathway
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    Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa
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    Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells
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    The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latency
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    Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development
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    Single-cell transcriptome profiling reveals immune and stromal cell heterogeneity in primary Sjögren’s syndrome
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    TGS1/PIMT regulates pro-inflammatory macrophage mediated paracrine insulin resistance: Crosstalk between macrophages and skeletal muscle cells
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  108. Sep 2023
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    Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus
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    TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice
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    Utilizing directed evolution to interrogate and optimize CRISPR/Cas guide RNA scaffolds
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    Spatially Distinct Otic Mesenchyme Cells show Molecular and Functional Heterogeneity Patterns Before Hearing Onset
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    Mitochondrial GTP metabolism controls reproductive aging in C. elegans
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    HTT (huntingtin) and RAB7 co-migrate retrogradely on a signaling LAMP1-containing late endosome during axonal injury
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    Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors
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  116. Aug 2023
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    Network analysis identifies strain-dependent response to tau and tau seeding-associated genes
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    Human Multi-Chimeric Cell (HMCC) Therapy as a Novel Approach for Tolerance Induction in Transplantation
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    Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.
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    Entry receptor LDLRAD3 is required for Venezuelan equine encephalitis virus peripheral infection and neurotropism leading to pathogenesis in mice
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    S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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  123. Jul 2023
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An enteroendocrine-microbial axis in the large intestine controls host metabolism
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      DOI: 10.21203/rs.3.rs-3112286/v1

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    Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model
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    mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching
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    Dendritic cell ICAM-1 strengthens synapses with CD8 T cells but is not required for their early differentiation
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    Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks
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  129. 52.53.155.43 52.53.155.43
    Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice
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  130. 52.53.155.43 52.53.155.43
    Newly-synthesized Glycoprotein Profiling to Identify Molecular Signatures of Warm Ischemic Injury in Donor Lungs
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    Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
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  132. Jun 2023
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    Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal
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    Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer
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    Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring
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  136. www.nature.com www.nature.com
    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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    MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis
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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Neuroligin-1 mutation associated with Alzheimer’s disease produces memory and age-dependent impairments in hippocampal plasticity
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  139. May 2023
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    Inflammatory and alternatively activated macrophages independently induce metaplasia but cooperatively drive pancreatic precancerous lesion growth
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    Tracer metabolomics reveals the role of aldose reductase in glycosylation
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    Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2
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    Transcriptional dynamics of delaminating neuroblasts in the mouse otic vesicle
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    Manipulating facial musculature with functional electrical stimulation as an intervention for major depressive disorder: a focused search of literature for a proposal
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    Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases
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    An in vivo neuroimmune organoid model to study human microglia phenotypes
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    ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells
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    Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment
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    Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes
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  150. Apr 2023
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    Salmonella invasion of a cell is self-limiting due to effector-driven activation of N-WASP
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    PHLPP1 regulates PINK1-parkin signalling and life span
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    Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
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    Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone
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  155. Mar 2023
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
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    Integrated metabolic and genetic analysis reveals distinct features of primary differentiated thyroid cancer and its metastatic potential in humans
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    Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination
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    Original research: Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy
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    Salmonella infection induces the reorganization of follicular dendritic cell networks concomitant with the failure to generate germinal centers
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    Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies
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    Osmotically evoked PLCδ1-dependent translocation of ΔN-TRPV1 channels in rat supraoptic neurons
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  163. www.embopress.org www.embopress.org
    The ion channel CALHM6 controls bacterial infection-induced cellular cross-talk at the immunological synapse
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    Stimulation of the beta-2-adrenergic receptor with salbutamol activates human brown adipose tissue
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    Annotation of putative circadian rhythm-associated genes in Diaphorina citri (Hemiptera: Liviidae)
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  166. Feb 2023
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    Tocilizumab treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants
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    Human hematopoietic stem cell vulnerability to ferroptosis
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    Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells
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  170. Jan 2023
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    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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    The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice
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    Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues
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  174. Dec 2022
  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Scratch-AID, a deep learning-based system for automatic detection of mouse scratching behavior with high accuracy
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  176. Nov 2022
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    A novel function for the sperm adhesion protein IZUMO1 in cell–cell fusion
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    Global profiling of the proteomic changes associated with the post-testicular maturation of mouse spermatozoa
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    Protocol to evaluate hyperlipidemia in zebrafish larvae
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    Developmental regulation of thalamus-driven pauses in striatal cholinergic interneurons
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    Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma
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  182. Oct 2022
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    SYK coordinates neuroprotective microglial responses in neurodegenerative disease
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    In vitro neurons learn and exhibit sentience when embodied in a simulated game-world
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    PARP-inhibition reprograms macrophages toward an anti-tumor phenotype
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    Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation
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  187. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Subclass-specific expression patterns of MET receptor tyrosine kinase during development in medial prefrontal and visual cortices
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      DOI: 10.1002/cne.25418

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  188. Sep 2022
  189. www.embopress.org www.embopress.org
    Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
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      DOI: 10.15252/embr.202154136

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  190. journals.plos.org journals.plos.org
    Blind spots on western blots: Assessment of common problems in western blot figures and methods reporting with recommendations to improve them
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      DOI: 10.1371/journal.pbio.3001783

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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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  192. www.sciencedirect.com www.sciencedirect.com
    Landscape and age dynamics of immune cells in the Egyptian rousette bat
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    sciencedirect.com/science/article/pii/S2211124722011299
  193. Aug 2022
  194. www.sciencedirect.com www.sciencedirect.com
    Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
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    Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development
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    SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis
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    Dual pancreatic adrenergic and dopaminergic signaling as a therapeutic target of bromocriptine
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    TOP1 CAD-seq: A protocol to map catalytically engaged topoisomerase 1 in human cells
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    Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter
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  200. Jul 2022
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    Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization
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    Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy
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    A Metabolic Regulatory Network for the Caenorhabditis elegans intestine
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    Multiomics reveal the central role of pentose phosphate pathway in resident thymic macrophages to cope with efferocytosis-associated stress
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    A single-cell analysis of thymopoiesis and thymic iNKT cell development in pigs
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  206. Jun 2022
  207. www.sciencedirect.com www.sciencedirect.com
    Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
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    Intrinsic Connectivity Networks of Glutamate-Mediated Antidepressant Response: A Neuroimaging Review
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    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
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    A brainstem circuit for nausea suppression
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    Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
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  212. www.biorxiv.org www.biorxiv.org
    Blind spots on western blots: a meta-research study highlighting opportunities to improve figures and methods reporting
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      DOI: 10.1101/2022.05.13.491761

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  213. May 2022
  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense
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      DOI: 10.7554/eLife.73625

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  215. Apr 2022
  216. www.sciencedirect.com www.sciencedirect.com
    Inflammation induces pro-NETotic neutrophils via TNFR2 signaling
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    A protocol for imaging calcium and chloride in C. elegans glia upon touch stimulation
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    Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease
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    Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches
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    FEBS Press
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  221. Mar 2022
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    Loss of mouse Stmn2 function causes motor neuropathy
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    Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication
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  224. aacrjournals.org aacrjournals.org
    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
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      DOI: 10.1158/2767-9764.CRC-21-0103

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  225. Feb 2022
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    Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability
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    PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP dependent lipid uptake and fatty acid synthesis pathways
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  228. Jan 2022
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    Machine Learning Models Predict the Primary Sites of Head and Neck Squamous Cell Carcinoma Metastases Based on DNA Methylation
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