Hypothesis

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Dec 2024
54.241.53.176 54.241.53.176

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1. scibot 12 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1007/s40265-020-01461-2
  
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54.241.53.176/29ba3ae16e2c379947f9b262b658da187a998c9f/s11684-024-1103-5-html.html
link.springer.com link.springer.com

LncRNA DANCR-V1 is a novel regulator of Wnt/β-catenin and TGF-β1/SMAD signaling pathways in colorectal cancer: an in vitro and in silico study

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1. scibot 12 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1007/s11033-024-10128-0
  
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link.springer.com/article/10.1007/s11033-024-10128-0
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Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) drives abnormal pericyte-rich vasculature in triple-negative breast cancer

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1. scibot 12 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1007/s10456-024-09956-2
  
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link.springer.com/article/10.1007/s10456-024-09956-2
onlinelibrary.wiley.com onlinelibrary.wiley.com

Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2

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1. scibot 12 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1002/ijc.35285
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.35285
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Genotypic and phylogeographic insights into a pre-epidemic variant of Wesselsbron virus detected in sylvatic Aedes mcintoshi from Semuliki Forest, Uganda

2
1. scibot 11 Dec 2024
  
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  CRL-3216
  
  DOI: 10.1128/spectrum.00914-24
  
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  Curator: @evieth
  
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2. scibot 11 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1128/spectrum.00914-24
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11619370/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Capicua C1 Domain Is Required for Full Activity of the CIC::DUX4 Fusion Oncoprotein

1
1. scibot 11 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1158/2767-9764.CRC-24-0348
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11626509/
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Protocol for detecting and quantifying hATF4-HA in non-stress versus stress conditions using automated and quantitative Jess western blotting

1
1. scibot 11 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.xpro.2024.103454
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11617455/
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

11
1. scibot 11 Dec 2024
  
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
2. scibot 10 Dec 2024
  
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
3. scibot 09 Dec 2024
  
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
4. scibot 08 Dec 2024
  
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
5. scibot 07 Dec 2024
  
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
6. scibot 06 Dec 2024
  
  in Public
  
  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
7. scibot 05 Dec 2024
  
  in Public
  
  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
8. scibot 04 Dec 2024
  
  in Public
  
  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
9. scibot 03 Dec 2024
  
  in Public
  
  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
10. scibot 02 Dec 2024
  
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
11. scibot 01 Dec 2024
  
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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sciencedirect.com/science/article/pii/S2211124724013111
52.53.155.43 52.53.155.43

1-s2.0-S2589004224027809-main-html.html

1
1. scibot 10 Dec 2024
  
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  ATCC Cat# CRL-3216
  
  DOI: 10.1016/j.isci.2024.111553
  
  Resource: (RRID:CVCL_0063)
  
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52.53.155.43/31dc3ee487cd850ff066e8bc3e177230e6d4ce46/1-s2.0-S2589004224027809-main-html.html
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Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening

1
1. scibot 10 Dec 2024
  
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  ATCCCat# CRL-3216
  
  DOI: 10.1016/j.cels.2024.11.004
  
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Optimized reporters for multiplexed detection of transcription factor activity

1
1. scibot 10 Dec 2024
  
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  ATCCCat#CRL-3216, RRID:CVCL_0063
  
  DOI: 10.1016/j.cels.2024.11.003
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11667439/
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1-s2.0-S2589004224027652-main-html.html

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1. scibot 10 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.isci.2024.111538
  
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The ATAC complex represses the transcriptional program of the autophagy-lysosome pathway via its E3 ubiquitin ligase activity

1
1. scibot 06 Dec 2024
  
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  ATCCCat# CRL-3216
  
  DOI: 10.1016/j.celrep.2024.115033
  
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sciencedirect.com/science/article/pii/S2211124724013846
52.53.155.43 52.53.155.43

Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport

3
1. scibot 06 Dec 2024
  
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  RRID: CVCL_0063
  
  DOI: 10.1016/j.celrep.2024.114357
  
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2. scibot 06 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.celrep.2024.114357
  
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3. scibot 06 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.celrep.2024.114357
  
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52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
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Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity

1
1. scibot 06 Dec 2024
  
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  ATCCCRL-3216
  
  DOI: 10.1016/j.ccell.2024.11.003
  
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sciencedirect.com/science/article/pii/S1535610824004380
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Reactive oxygen species control protein degradation at the mitochondrial import gate

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1. scibot 06 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.molcel.2024.11.004
  
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Bivalent SMAC mimetic APG-1387 reduces HIV reservoirs and limits viral rebound in humanized mice

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1. scibot 06 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.isci.2024.111470
  
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52.53.155.43/f9ca87b1abaf28874b4c47b89498458fbdf5e637/1-s2.0-S258900422402697X-main-html.html
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CD97 maintains tumorigenicity of glioblastoma stem cells via mTORC2 signaling and is targeted by CAR Th9 cells

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1. scibot 05 Dec 2024
  
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  ATCCCat# CRL-3216
  
  DOI: 10.1016/j.xcrm.2024.101844
  
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sciencedirect.com/science/article/pii/S2666379124006153
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DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states

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1. scibot 05 Dec 2024
  
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  ATCCCRL-3216
  
  DOI: 10.1016/j.molcel.2024.11.009
  
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T-Switch: A specificity-based engineering platform for developing safe and effective T cell therapeutics

2
1. scibot 05 Dec 2024
  
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  ATCCATCC Cat# CRL-3216
  
  DOI: 10.1016/j.immuni.2024.11.009
  
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2. scibot 05 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.immuni.2024.11.009
  
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KPNA3 regulates histone locus body formation by modulating condensation and nuclear import of NPAT

1
1. scibot 05 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1083/jcb.202401036
  
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rupress.org/jcb/article/224/1/e202401036/277130/KPNA3-regulates-histone-locus-body-formation-by
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Recruitment of autophagy initiator TAX1BP1 advances aggrephagy from cargo collection to sequestration

1
1. scibot 05 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1038/s44318-024-00280-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11611905/
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Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma

1
1. scibot 05 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.celrep.2024.115026
  
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sciencedirect.com/science/article/pii/S2211124724013779
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Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer

1
1. scibot 03 Dec 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1126/scisignal.adp1375
  
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science.org/doi/10.1126/scisignal.adp1375
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The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release

1
1. scibot 02 Dec 2024
  
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  Cat.#CRL-3216
  
  DOI: 10.1016/j.molcel.2024.10.046
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @vtello
  
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sciencedirect.com/science/article/pii/S1097276524008852
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Carbonic anhydrase 2 facilitates sorafenib resistance by counteracting MCT4-mediated intracellular pH dysregulation in HCC

1
1. scibot 02 Dec 2024
  
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  Cat#CRL-3216
  
  DOI: 10.1016/j.celrep.2024.114996
  
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sciencedirect.com/science/article/pii/S2211124724013470
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B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies

1
1. scibot 02 Dec 2024
  
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  CVCL_0063
  
  DOI: 10.1016/j.ebiom.2024.105459
  
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sciencedirect.com/science/article/pii/S235239642400495X
Nov 2024
pubs.acs.org pubs.acs.org

Identification of Small-Molecule Antagonists Targeting the Growth Hormone Releasing Hormone Receptor (GHRHR)

2
1. scibot 29 Nov 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.1021/acs.jcim.4c00577
  
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  DOI: 10.1021/acs.jcim.4c00577
  
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

2
1. scibot 29 Nov 2024
  
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0063
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  RRID:CVCL_0063
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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Innervation density governs crosstalk of GPCR-based norepinephrine and dopamine sensors

1
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  RRID:CVCL_0063
  
  DOI: 10.1101/2024.11.23.624963
  
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Schwann cell C5aR1 co-opts inflammasome NLRP1 to sustain pain in a mouse model of endometriosis

1
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  RRID:CVCL_0063
  
  DOI: 10.1038/s41467-024-54486-6
  
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RNA helicases DDX3X and DDX3Y form nanometer-scale RNA-protein clusters that support catalytic activity

1
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.cub.2024.10.055
  
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A peptide encoded by LINC00944 suppresses the growth of melanoma cells by diminishing EP400-MYC interaction

1
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  RRID:CVCL_0063
  
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Protocols for rapid identification of small-molecule metabolite ligands interacting with proteins

1
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  CRL-3216
  
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Increased translation driven by non-canonical EZH2 creates a synthetic vulnerability in enzalutamide-resistant prostate cancer

1
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  RRID:CVCL_0063
  
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MicroRNA-145-5p inhibits the tumorigenesis of breast cancer through SENP2-regulated ubiquitination of ERK2

1
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  RRID:CVCL_0063
  
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Berbamine prevents SARS-CoV-2 entry and transmission

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ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

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  Cat#CRL-3216
  
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Solid tumor immunotherapy using NKG2D-based adaptor CAR T cells

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Identification of a non-canonical planar cell polarity pathway triggered by light in the developing mouse retina

1
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Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency

1
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CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2

1
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  DOI: 10.1038/s44318-024-00240-z
  
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C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers

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Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma

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  ATCC CRL-3216
  
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Engineered IscB-ωRNA system with improved base editing efficiency for disease correction via single AAV delivery in mice

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Profound synthetic lethality between SMARCAL1 and FANCM

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Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function

1
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Autophagy-dependent splicing control directs translation toward inflammation during senescence

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Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress

1
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Structure of the TXNL1-bound proteasome

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Plausible, robust biological oscillations through allelic buffering

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Acute multi-level response to defective de novo chromatin assembly in S-phase

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A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites

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Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes

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  CRL-3216
  
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Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune microenvironment

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mcr-24-0433-html.html

1
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can-24-1817-html.html

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Ehbp1 orchestrates orderly sorting of Wnt/Wingless to the basolateral and apical cell membranes

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Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways

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wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html

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A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells

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Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment

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USP7 deubiquitinates KRAS and promotes non-small cell lung cancer

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  DOI: 10.1016/j.celrep.2024.114917
  
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FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma

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Residue Y362 is crucial for FLIPL to impart catalytic activity to pro-caspase-8 to suppress necroptosis

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ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma

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Rab11-Rab8 cascade dynamics in primary cilia and membrane tubules

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Characterization of novel nitazene recreational drugs: Insights into their risk potential from in vitro µ-opioid receptor assays and in vivo behavioral studies in mice

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Longitudinal effects of SARS-CoV-2 breakthrough infection on imprinting of neutralizing antibody responses

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Activation of estrogen-related receptor γ by calcium and cadmium

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The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer

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A novel ITGB8 transcript variant sustains ovarian cancer cell survival through genomic instability and altered ploidy on a mutant p53 background

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Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance

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Protocol for mapping differential protein-protein interaction networks using affinity purification-mass spectrometry

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Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma

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ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin

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Requirement of Nek2a and cyclin A2 for Wapl-dependent removal of cohesin from prophase chromatin

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Protocol to identify E3 ligases amenable to biodegraders using a cell-based screening

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effects_of_p301l_tau_on_post_translational.25-html.html

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Upregulation of circ0000381 attenuates microglial/macrophage pyroptosis after spinal cord injury

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Asparagine614 Determines the Transport and Function of the Murine Anti-Aging Protein Klotho

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Beyond Glycolysis: Aldolase A Is a Novel Effector in Reelin-Mediated Dendritic Development

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Linkage-specific ubiquitin binding interfaces modulate the activity of the chlamydial deubiquitinase Cdu1 towards poly-ubiquitin substrates

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Design, performance, processing, and validation of a pooled CRISPR perturbation screen for bacterial toxins

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Robust SARS-CoV-2-neutralizing antibodies sustained through 6 months post XBB.1.5 mRNA vaccine booster

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Single-chain A35R-M1R-B6R trivalent mRNA vaccines protect mice against both mpox virus and vaccinia virus

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Type I IFN drives unconventional IL-1β secretion in lupus monocytes

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Targeting RSV-neutralizing B cell receptors with anti-idiotypic antibodies

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Multi-omic human pancreatic islet endoplasmic reticulum and cytokine stress response mapping provides type 2 diabetes genetic insights

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Inhibition of O-GlcNAc transferase activates type I interferon-dependent antitumor immunity by bridging cGAS-STING pathway

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Antitumor effects of intracranial injection of B7-H3-targeted Car-T and Car-Nk cells in a patient-derived glioblastoma xenograft model

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Inhibition of EREG/ErbB/ERK by Astragaloside IV reversed taxol-resistance of non-small cell lung cancer through attenuation of stemness via TGFβ and Hedgehog signal pathway

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SIAH3 is frequently epigenetically silenced in cancer and regulates mitochondrial metabolism

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FEBS Press

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BPS Publications

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High specificity of engineered T cells with third generation CAR (CD28-4-1BB-CD3-ζ) based on biotin-bound monomeric streptavidin for potential tumor immunotherapy

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Sirtuin 1/sirtuin 3 are robust lysine delactylases and sirtuin 1-mediated delactylation regulates glycolysis

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The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels

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Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer

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PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer

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A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis

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Use of synthetic circular RNA spike-ins (SynCRS) for normalization of circular RNA sequencing data

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Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation

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A novel HER2-specific sensor based on DARPin_9–29 and albumin binding domain for real-time fluorescence-guided tumor detection in animal model of cancer

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Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute myeloid leukemia

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An arms race between 5’ppp-RNA virus and its alternative recognition receptor MDA5 in RIG-I-lost teleost fish

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Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia

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YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma

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Protocol for the efficient and inducible generation of CRISPR-Cas9-edited human cortical neurons from the iCas9-iNgn2 hPSCs

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Pervasive mislocalization of pathogenic coding variants underlying human disorders

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The TMEM132B-GABAA receptor complex controls alcohol actions in the brain

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Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance

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Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application

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Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy

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Decoding Missense Variants by Incorporating Phase Separation via Machine Learning

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Type-II kinase inhibitors that target Parkinson’s Disease-associated LRRK2

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Saturation mutagenesis-reinforced functional assays for disease-related genes

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A sustained calcium response mediated by IP3 receptor anchoring to the desmosome is essential for apoptotic cell elimination

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Histamine H3 receptor antagonist/nitric oxide donors as novel promising therapeutic hybrid-tools for glaucoma and retinal neuroprotection

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FEBS Press

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Discovery and characterization of a pan-betacoronavirus S2-binding antibody

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Identification of the orphan GPR25 as a receptor of the chemokine CXCL17

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FEBS Press

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Altered epitopes enhance macrophage-mediated anti-tumour immunity to low-immunogenic tumour mutations

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PEBP1 amplifies mitochondrial dysfunction induced integrated stress response

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BPS Publications

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Identification of Small-Molecule Antagonists Targeting the Growth Hormone Releasing Hormone Receptor (GHRHR)

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ZEB1 Inhibits LHβ Subunit Transcription When Overexpressed, but Is Dispensable for LH Synthesis in Mice

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Identify BCAT1 plays an oncogenic role and promotes EMT in KIRC via single cell RNA-seq and experiment

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EGF/EGFR-YAP1/TEAD2 signaling upregulates STIM1 in vemurafenib resistant melanoma cells

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Induction of immortal-like and functional CAR T cells by defined factors

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Reverse mutational scanning of spike BA.2.86 identifies the epitopes contributing to immune escape from polyclonal sera

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ZNF521 promotes acute myeloid leukemogenesis by suppressing the expression and acetylation of SMC3

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Protocol for monitoring phagocytosis of cancer cells by TAM-like macrophages using imaging cytometry

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Protocol for preparing metabolically reprogrammed human CAR T cells and evaluating their in vitro effects

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Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan

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  Cat#CRL-3216
  
  DOI: 10.1016/j.str.2024.08.019
  
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Geranylgeranylated SCFFBXO10 regulates selective outer mitochondrial membrane proteostasis and function

1
1. scibot 25 Sep 2024
  
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  Cat#CRL-3216
  
  DOI: 10.1016/j.celrep.2024.114783
  
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Reconstitution of BNIP3/NIX-mediated autophagy reveals two pathways and hierarchical flexibility of the initiation machinery

1
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  RRID:CVCL_0063
  
  DOI: 10.1101/2024.08.28.609967
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11383309/
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A TBK1-independent primordial function of STING in lysosomal biogenesis

1
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  Cat#CRL-3216
  
  DOI: 10.1016/j.molcel.2024.08.026
  
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mCAUSE: Prioritizing Mitochondrial Targets that Alleviate Pancreatic Cancer Cell Phenotypes

1
1. scibot 25 Sep 2024
  
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  CRL-3216
  
  DOI: 10.1016/j.isci.2024.110880
  
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Global isonicotinylome analysis identified SMAD3 isonicotinylation promotes liver cancer cell epithelial–mesenchymal transition and invasion

1
1. scibot 25 Sep 2024
  
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  ATCC CRL-3216
  
  DOI: 10.1016/j.isci.2024.110775
  
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CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway

1
1. scibot 25 Sep 2024
  
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  CRL-3216
  
  DOI: 10.1016/j.isci.2024.110832
  
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Intracellular Ebola virus nucleocapsid assembly revealed by in situ cryo-electron tomography

1
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  Cat#CRL-3216
  
  DOI: 10.1016/j.cell.2024.08.044
  
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Prominin 1 and Tweety Homology 1 both induce extracellular vesicle formation

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.7554/eLife.100061
  
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Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer

1
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.ccell.2024.08.018
  
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A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson’s disease

1
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.cell.2024.08.046
  
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Novel immunotherapeutics against LGR5 to target multiple cancer types

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  RRID:CVCL_0063
  
  DOI: 10.1038/s44321-024-00121-2
  
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Redox-dependent condensation and cytoplasmic granulation by human ssDNA-binding protein-1 delineate roles in oxidative stress response

1
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  CVCL_0063
  
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Gambogic acid impairs the maintenance and therapeutic resistance of glioma stem cells by targeting B-cell-specific Moloney leukemia virus insert site 1

1
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.phymed.2024.156070
  
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A mechanism in Agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.7554/eLife.49180
  
  Resource: (RRID:CVCL_0042)
  
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  SciCrunch record: RRID:CVCL_0042
  
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A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge

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  RRID:CVCL_0063
  
  DOI: 10.1016/j.celrep.2019.08.047
  
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Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_0042
  
  DOI: 10.7554/eLife.45303
  
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Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons

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  RRID:CVCL_0063
  
  DOI: 10.1016/j.neuron.2019.05.043
  
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Regulatory switch at the cytoplasmic interface controls TRPV channel gating

1
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  RRID:CVCL_0063
  
  DOI: 10.7554/eLife.47746
  
  Resource: (RRID:CVCL_1926)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6538378/
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Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers

1
1. scibot 25 Sep 2024
  
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  RRID:SCR_003163
  
  DOI: 10.7554/eLife.43186
  
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RBN-2397, a PARP7 Inhibitor, Synergizes with Paclitaxel to Inhibit Proliferation and Migration of Ovarian Cancer Cells

1
1. scibot 18 Sep 2024
  
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  RRID:CVC_0063
  
  DOI: 10.1101/2024.08.20.608802
  
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Stenotrophomonas maltophilia provokes NEU1-mediated release of a flagellin-binding decoy receptor that protects against lethal infection

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  Cat# CRL-3216
  
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Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation

1
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  CRL-3216™
  
  DOI: 10.1016/j.celrep.2024.114736
  
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Neoself-antigens are the primary target for autoreactive T cells in human lupus

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  RCB2202
  
  DOI: 10.1016/j.cell.2024.08.025
  
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Protocol to identify receptors of secreted proteins through CRISPR-Cas9 whole-genome screening technology

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  RRID:CVCL_0063
  
  DOI: 10.1016/j.xpro.2024.103315
  
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Computational pipeline predicting cell death suppressors as targets for cancer therapy

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  RRID:CVCL_0063
  
  DOI: 10.1016/j.isci.2024.110859
  
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Validation of a PD-1/CD28 chimeric switch receptor to augment CAR-T function in dogs with spontaneous B cell lymphoma

1
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.isci.2024.110863
  
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Sorafenib and SIAIS361034, a novel PROTAC degrader of BCL-xL, display synergistic antitumor effects on hepatocellular carcinoma with minimal hepatotoxicity

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  RRID:CVCL_0063
  
  DOI: 10.1016/j.bcp.2024.116542
  
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A guide to selecting high-performing antibodies for Huntingtin (UniProt ID: P42858) for use in western blot, immunoprecipitation, and immunofluorescence

1
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  CVCL_0063
  
  DOI: 10.12688/f1000research.153670.1
  
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MG53 suppresses tumor growth via transcriptional inhibition of KIF11 in pancreatic cancer

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  RRID:CVCL_0063
  
  DOI: 10.1016/j.tranon.2024.102118
  
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Distinct tumor architectures and microenvironments for the initiation of breast cancer metastasis in the brain

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  ATCC #: CRL-3216
  
  DOI: 10.1016/j.ccell.2024.08.015
  
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RAPIDASH: Tag-free enrichment of ribosome-associated proteins reveals composition dynamics in embryonic tissue, cancer cells, and macrophages

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  Cat# CRL-3216
  
  DOI: 10.1016/j.molcel.2024.08.023
  
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febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
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  RRID:CVCL_0063
  
  DOI: 10.1002/1873-3468.15010
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.15010
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A nature-inspired HIF stabilizer derived from a highland-adaptation insertion of plateau pika Epas1 protein

1
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  RRID:CVCL_0063
  
  DOI: 10.1016/j.celrep.2024.114727
  
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FEBS Press

1
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  RRID:CVCL_0063
  
  DOI: 10.1111/febs.17264
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.17264
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Clofazimine inhibits innate immunity against Mycobacterium tuberculosis by NF-κB

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  RRID:CVCL_0063
  
  DOI: 10.1128/msphere.00254-24
  
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TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival

1
1. scibot 12 Sep 2024
  
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  Cat# CRL-3216
  
  DOI: 10.1016/j.cell.2024.08.020
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_0063
  
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sciencedirect.com/science/article/pii/S0092867424009115
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RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis

1
1. scibot 12 Sep 2024
  
  in Public
  
  RRID:CVCL_0063
  
  DOI: 10.1158/0008-5472.CAN-23-2081
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
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New dual inducible cellular model to investigate temporal control of oncogenic cooperating genes

1
1. scibot 12 Sep 2024
  
  in Public
  
  RRID:CVCL_0063
  
  DOI: 10.1038/s41598-024-71227-3
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11377716/
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Circular RNA HMGCS1 sponges MIR4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction

1
1. scibot 12 Sep 2024
  
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  RRID:CVCL_0063
  
  DOI: 10.7554/eLife.97267
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0063
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11377038/
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Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis

1
1. scibot 11 Sep 2024
  
  in Public
  
  CRL-3216
  
  DOI: 10.1016/j.celrep.2024.114728
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_0063
  
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sciencedirect.com/science/article/pii/S2211124724010799
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Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia

1
1. scibot 10 Sep 2024
  
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  Cat# CRL-3216
  
  DOI: 10.1016/j.celrep.2024.114691
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_0063
  
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sciencedirect.com/science/article/pii/S2211124724010428
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Intestinal newborn regulatory B cell antibodies modulate microbiota communities

1
1. scibot 10 Sep 2024
  
  in Public
  
  CRL-3216
  
  DOI: 10.1016/j.chom.2024.08.010
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_0063
  
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sciencedirect.com/science/article/pii/S1931312824003172
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TGF-β and RAS jointly unmask primed enhancers to drive metastasis

1
1. scibot 10 Sep 2024
  
  in Public
  
  ATCC #: CRL-3216
  
  DOI: 10.1016/j.cell.2024.08.014
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_0063
  
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sciencedirect.com/science/article/pii/S009286742400905X
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Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity

1
1. scibot 10 Sep 2024
  
  in Public
  
  CRL-3216
  
  DOI: 10.1016/j.cell.2024.08.007
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_0063
  
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sciencedirect.com/science/article/pii/S0092867424008985
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CD34 distribution in C-fiber low threshold mechanoreceptors in the mouse dorsal root ganglion and spinal cord

1
1. scibot 10 Sep 2024
  
  in Public
  
  RCB2202
  
  DOI: 10.1016/j.brainres.2024.149227
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_0063
  
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sciencedirect.com/science/article/pii/S0006899324004815
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Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy

1
1. scibot 10 Sep 2024
  
  in Public
  
  RRID:CVCL_0063
  
  DOI: 10.1016/j.cell.2024.08.013
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0063
  
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sciencedirect.com/science/article/pii/S0092867424009048
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Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD

1
1. scibot 10 Sep 2024
  
  in Public
  
  RRID:CVCL_0063
  
  DOI: 10.1016/j.xcrm.2024.101732
  
  Resource: (RRID:CVCL_0063)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2666379124004622

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