5,955 Matching Annotations
  1. Dec 2021
  2. www.sciencedirect.com www.sciencedirect.com
    The microglial P2Y6 receptor mediates neuronal loss and memory deficits in neurodegeneration
    1
    1. scibot 29 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110148

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    sciencedirect.com/science/article/pii/S2211124721016442
  3. crc.aacrjournals.org crc.aacrjournals.org
    The ADAM17-directed Inhibitory Antibody MEDI3622 Antagonizes Radiotherapy-induced VEGF Release and Sensitizes Non–Small Cell Lung Cancer for RadiotherapyADAM17-mediated Radioresistance
    1
    1. scibot 28 Dec 2021
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      DOI: 10.1158/2767-9764.CRC-21-0067

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    crc.aacrjournals.org/cancerrescommun/article/1/3/164/665523/The-ADAM17-directed-Inhibitory-Antibody-MEDI3622
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    Fish waves as emergent collective antipredator behavior
    1
    1. scibot 23 Dec 2021
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      DOI: 10.1016/j.cub.2021.11.068

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    sciencedirect.com/science/article/pii/S0960982221016547
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    A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo
    1
    1. scibot 23 Dec 2021
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      DOI: 10.1016/j.neuron.2021.11.027

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    sciencedirect.com/science/article/pii/S0896627321009880
  6. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Myofibre injury induces capillary disruption and regeneration of disorganized microvascular networks
    1
    1. scibot 22 Dec 2021
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      DOI: 10.1113/JP282292

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    physoc.onlinelibrary.wiley.com/doi/epdf/10.1113/JP282292
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    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
    1
    1. scibot 22 Dec 2021
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      DOI: 10.1007/s10863-018-9750-3

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    link.springer.com/article/10.1007/s10863-018-9750-3
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    Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice
    1
    1. scibot 22 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110152

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    sciencedirect.com/science/article/pii/S221112472101648X
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    BPS Publications
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    1. scibot 21 Dec 2021
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      DOI: 10.1111/bph.15720

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15720
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    BPS Publications
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    1. scibot 21 Dec 2021
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      DOI: 10.1111/bph.15693

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15693
  11. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Analgesic α-conotoxins modulate native and recombinant GIRK1/2 channels via GABAB receptor activation and reduce neuroexcitability
    1
    1. scibot 21 Dec 2021
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      DOI: 10.1111/bph.15690

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15690
  12. f1000research.com f1000research.com
    Ethanol consumption during gestation promotes placental alterations in IGF-1 deficient mice
    1
    1. scibot 21 Dec 2021
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      DOI: 10.12688/f1000research.75116.1

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    f1000research.com/articles/10-1284
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    ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion
    1
    1. scibot 21 Dec 2021
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      DOI: 10.1016/j.devcel.2021.11.022

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    sciencedirect.com/science/article/pii/S1534580721009461
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    MicroRNA-193b impairs muscle growth in mouse models of type 2 diabetes by targeting the PDK1/Akt signalling pathway
    1
    1. scibot 17 Dec 2021
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      DOI: 10.1007/s00125-021-05616-y

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    link.springer.com/article/10.1007/s00125-021-05616-y
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
    1
    1. scibot 17 Dec 2021
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      DOI: 10.7554/eLife.69729

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    ncbi.nlm.nih.gov/pmc/articles/PMC8668188/
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Impact of monomeric and aggregated wild-type and A30P/A53T double-mutant α-synuclein on antioxidant mechanism and glutamate metabolic profile of cultured astrocytes
    1
    1. scibot 15 Dec 2021
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      DOI: 10.1002/jnr.24994

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24994
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease
    1
    1. scibot 15 Dec 2021
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      DOI: 10.7554/eLife.73753

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    ncbi.nlm.nih.gov/pmc/articles/PMC8660019/
  18. elifesciences.org elifesciences.org
    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
    1
    1. scibot 15 Dec 2021
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      DOI: 10.7554/eLife.68487

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    elifesciences.org/articles/68487
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of SARS-CoV-2 spike protein binding to ACE2 in living cells by TR-FRET
    1
    1. scibot 15 Dec 2021
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      DOI: 10.1016/j.xpro.2021.101024

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    ncbi.nlm.nih.gov/pmc/articles/PMC8606263/
  20. www.sciencedirect.com www.sciencedirect.com
    Pleiotropic vascular effects of ivabradine in streptozotocin-induced diabetes
    1
    1. scibot 15 Dec 2021
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      DOI: 10.1016/j.ejphar.2021.174551

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    sciencedirect.com/science/article/pii/S001429992100707X
  21. www.sciencedirect.com www.sciencedirect.com
    KLF15 overexpression in myocytes fails to ameliorate ALS-related pathology or extend the lifespan of SOD1G93A mice
    1
    1. scibot 15 Dec 2021
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      DOI: 10.1016/j.nbd.2021.105583

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    sciencedirect.com/science/article/pii/S0969996121003326
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A recombinant protein containing influenza viral conserved epitopes and superantigen induces broad-spectrum protection
    1
    1. scibot 11 Dec 2021
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      DOI: 10.7554/eLife.71725

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    ncbi.nlm.nih.gov/pmc/articles/PMC8635977/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    lncRNA BORG:TRIM28 Complexes Drive Metastatic Progression by Inducing α6 Integrin/CD49f Expression in Breast Cancer Stem Cells
    1
    1. scibot 11 Dec 2021
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      DOI: 10.1158/1541-7786.MCR-21-0137

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    ncbi.nlm.nih.gov/pmc/articles/PMC8642309/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TLR4 Associated Signaling Disrupters as a New Means to Overcome HERV-W Envelope-Mediated Myelination Deficits
    1
    1. scibot 11 Dec 2021
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      DOI: 10.3389/fncel.2021.777542

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    ncbi.nlm.nih.gov/pmc/articles/PMC8650005/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIF2 Regulates Intestinal Wnt5a Expression
    1
    1. scibot 11 Dec 2021
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      DOI: 10.3389/fonc.2021.769385

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    ncbi.nlm.nih.gov/pmc/articles/PMC8656274/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Mechanisms Underlying the Protective Action of Selenium Nanoparticles against Ischemia/Reoxygenation Are Mediated by the Activation of the Ca2+ Signaling System of Astrocytes and Reactive Astrogliosis
    1
    1. scibot 11 Dec 2021
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      DOI: 10.3390/ijms222312825

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    ncbi.nlm.nih.gov/pmc/articles/PMC8657910/
  27. elifesciences.org elifesciences.org
    Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology
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    1. scibot 11 Dec 2021
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      DOI: 10.7554/eLife.73430

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    elifesciences.org/articles/73430
  28. www.sciencedirect.com www.sciencedirect.com
    Coordinated repression of pro-differentiation genes via P-bodies and transcription maintains Drosophila intestinal stem cell identity
    1
    1. scibot 07 Dec 2021
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      DOI: 10.1016/j.cub.2021.11.032

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    sciencedirect.com/science/article/pii/S0960982221015918
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockdown of heterogeneous nuclear ribonucleoprotein A1 results in neurite damage, altered stress granule biology and cellular toxicity in differentiated neuronal cells
    1
    1. scibot 04 Dec 2021
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      DOI: 10.1523/ENEURO.0350-21.2021

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    ncbi.nlm.nih.gov/pmc/articles/PMC8607908/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mesoscale organization of syntaxin 1A and SNAP25 is determined by SNARE–SNARE interactions
    1
    1. scibot 04 Dec 2021
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      DOI: 10.7554/eLife.69236

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    ncbi.nlm.nih.gov/pmc/articles/PMC8629428/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 With Angiotensin II Type 1 Receptor Impacts Mitochondrial Quality Control, Offering Promise for the Treatment of Vascular Senescence
    1
    1. scibot 04 Dec 2021
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      DOI: 10.3389/fcvm.2021.788655

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    ncbi.nlm.nih.gov/pmc/articles/PMC8637926/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors
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    1. scibot 04 Dec 2021
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      DOI: 10.7554/eLife.74276

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    ncbi.nlm.nih.gov/pmc/articles/PMC8631942/
  33. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Cell adhesion molecule L1 interacts with the chromo shadow domain of heterochromatin protein 1 isoforms α, β, and ɣ via its intracellular domain
    1
    1. scibot 04 Dec 2021
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      DOI: 10.1096/fj.202100816R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100816R
  34. journals.sagepub.com journals.sagepub.com
    Effects of Manipulation of Noradrenergic Activities on the Expression of Dopaminergic Phenotypes in Aged Rat Brains
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      DOI: 10.1177/17590914211055064

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      DOI: 10.1177/17590914211055064

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    journals.sagepub.com/doi/full/10.1177/17590914211055064
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling
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      DOI: 10.1371/journal.pbio.3001432

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    ncbi.nlm.nih.gov/pmc/articles/PMC8610276/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted therapy to β3 integrin reduces chemoresistance in breast cancer bone metastases
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      DOI: 10.1158/1535-7163.MCT-20-0931

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    ncbi.nlm.nih.gov/pmc/articles/PMC8442608/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radium 223 treatment increase immune checkpoint expression in extracellular vesicles from the metastatic prostate cancer bone microenvironment
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      DOI: 10.1158/1078-0432.CCR-20-4790

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    ncbi.nlm.nih.gov/pmc/articles/PMC8172463/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells
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      DOI: 10.1016/j.isci.2021.103349

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    ncbi.nlm.nih.gov/pmc/articles/PMC8603209/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximity labeling identifies LOTUS domain proteins that promote the formation of perinuclear germ granules in C. elegans
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      DOI: 10.7554/eLife.72276

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    ncbi.nlm.nih.gov/pmc/articles/PMC8616582/
  40. www.sciencedirect.com www.sciencedirect.com
    Opto-vTrap, an optogenetic trap for reversible inhibition of vesicular release, synaptic transmission, and behavior
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      DOI: 10.1016/j.neuron.2021.11.003

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    sciencedirect.com/science/article/pii/S0896627321008965
  41. Nov 2021
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts
    1
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      DOI: 10.1016/j.neuron.2019.02.034

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    ncbi.nlm.nih.gov/pmc/articles/PMC8608148/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Strategies for Intensity-Dependent Olfactory Processing in Caenorhabditis elegans
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    A Note of Caution: Gramicidin Affects Signaling Pathways Independently of Its Effects on Plasma Membrane Conductance
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    MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal
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    Long-term hypogonadism diminishes the neuroprotective effects of dietary genistein in young adult ovariectomized rats after transient focal ischemia
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    Deep Learning to Decipher the Progression and Morphology of Axonal Degeneration
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    A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
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    Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission
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    Optical Coherence Tomography Angiography Characteristics Serve as Retinal Vein Occlusion Therapeutic Biomarkers for Dexamethasone Intravitreal Implant
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    A Role for Translational Regulation by S6 Kinase and a Downstream Target in Inflammatory Pain
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    Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast
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  129. www.hindawi.com www.hindawi.com
    Depichering the Effects of Astragaloside IV on AD-Like Phenotypes: A Systematic and Experimental Investigation
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    DYSFUNCTION OF OLIGODENDROCYTE INWARDLY RECTIFYING POTASSIUM CHANNEL IN A RAT MODEL OF AMYOTROPHIC LATERAL SCLEROSIS
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  131. www.hindawi.com www.hindawi.com
    Optical Coherence Tomography Angiography Characteristics Serve as Retinal Vein Occlusion Therapeutic Biomarkers for Dexamethasone Intravitreal Implant
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    Andrographolide prevents bone loss via targeting ERRalpha-regulated metabolic adaption of osteoclastogenesis
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MACF1 controls skeletal muscle function through the microtubule-dependent localization of extra-synaptic myonuclei and mitochondria biogenesis
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sexual Experience Induces the Expression of Gastrin-Releasing Peptide and Oxytocin Receptors in the Spinal Ejaculation Generator in Rats
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      DOI: 10.3390/ijms221910362

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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Secondary metabolites of Hülle cells mediate protection of fungal reproductive and overwintering structures against fungivorous animals
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  137. www.sciencedirect.com www.sciencedirect.com
    GluN2B S1303 phosphorylation by CaMKII or DAPK1: no indication for involvement in ischemia or LTP
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    sciencedirect.com/science/article/pii/S2589004221011822
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    Interleukin-6 Promotes Microtubule Stability in Axons via Stat3 Protein-Protein Interactions
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    A hierarchical processing unit for multi-component behavior in the avian brain
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    Gene bookmarking by the heat shock transcription factor programs the insulin-like signaling pathway
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A seven-residue deletion in PrP leads to generation of a spontaneous prion formed from C-terminal C1 fragment of PrP
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    Mechanoreceptor synapses in the brainstem shape the central representation of touch
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circadian regulation of vertebrate cone photoreceptor function
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  146. www.sciencedirect.com www.sciencedirect.com
    Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depichering the Effects of Astragaloside IV on AD-Like Phenotypes: A Systematic and Experimental Investigation
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  148. www.sciencedirect.com www.sciencedirect.com
    CHD1 controls H3.3 incorporation in adult brain chromatin to maintain metabolic homeostasis and normal lifespan
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    Bombesin-like peptide recruits disinhibitory cortical circuits and enhances fear memories
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The interplay of RNA:DNA hybrid structure and G-quadruplexes determines the outcome of R-loop-replisome collisions
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  151. www.jneurosci.org www.jneurosci.org
    G-protein-gated inwardly rectifying potassium (Kir3/GIRK) channels govern synaptic plasticity that supports hippocampal-dependent cognitive functions in male mice
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  152. link.springer.com link.springer.com
    Decoupling of female phonotaxis and mating propensity in a tree cricket
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    Spt4 facilitates the movement of RNA polymerase II through the +2 nucleosomal barrier
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  155. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Morphological assessment of GABA and glutamate inputs to GnRH neurons in intact female mice using expansion microscopy
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    Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19
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    Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy
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    Distinct interhemispheric connectivity at the level of the olfactory bulb emerges during Xenopus laevis metamorphosis
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    Quantifying spatial position in a branched structure in immunostained mouse tissue sections
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    The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon
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    A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Task-specific roles of local interneurons for inter- and intraglomerular signaling in the insect antennal lobe
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  165. link.springer.com link.springer.com
    Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis
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    Revisiting astrocyte to neuron conversion with lineage tracing in vivo
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    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons
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    A prion accelerates proliferation at the expense of lifespan
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  170. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Skeletal muscle type-specific mitochondrial adaptation to high-fat diet relies on differential autophagy modulation
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    Aging disrupts the temporal organization of antioxidant defenses in the heart of male rats and phase shifts circadian rhythms of systolic blood pressure
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    A Comparative Study of the Effect of Anatomical Site on Multiple Differentiation of Adipose-Derived Stem Cells in Rats
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  173. www.sciencedirect.com www.sciencedirect.com
    High fat / high cholesterol diet does not provoke atherosclerosis in the ω3-and ω6-polyunsaturated fatty acid synthesis inactivated Δ6-fatty acid desaturase deficient mouse
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STING nuclear partners contribute to innate immune signaling responses
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  175. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Loss of CX3CR1 augments neutrophil infiltration into cochlear tissues after acoustic overstimulation
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    The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolytic preconditioning in astrocytes mitigates trauma-induced neurodegeneration
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development and Functional Characterization of Fetal Lung Organoids
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endothelial pannexin 1–TRPV4 channel signaling lowers pulmonary arterial pressure in mice
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    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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    Single-cell secretion analysis reveals a dual role for IL-10 in restraining and resolving the TLR4-induced inflammatory response
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    Kainate receptors regulate the functional properties of young adult-born dentate granule cells
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    Ancient role of sulfakinin/cholecystokinin-type signalling in inhibitory regulation of feeding processes revealed in an echinoderm
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    The amyloid precursor protein is a conserved Wnt receptor
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
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    Cyclical phosphorylation of LRAP35a and CLASP2 by GSK3β and CK1δ regulates EB1-dependent MT dynamics in cell migration
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    Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites
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    Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dorsal clock neurons in Drosophila sculpt locomotor outputs but are dispensable for circadian activity rhythms
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave
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    Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells
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    A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth
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    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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    Cocaine shifts dopamine D2 receptor sensitivity to gate conditioned behaviors
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    Utilizing mouse optic nerve crush to examine CNS remyelination
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    Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2
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    Controlled lipid β-oxidation and carnitine biosynthesis by a vitamin D metabolite
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    Reelin Is Required for Maintenance of Granule Cell Lamination in the Healthy and Epileptic Hippocampus
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    Inhibition of Postn Rescues Myogenesis Defects in Myotonic Dystrophy Type 1 Myoblast Model
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    Cryoprotective Effect of Pentoxifylline on Spermatogonial Stem Cell During Transplantation into Azoospermic Torsion Mouse Model
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      DOI: 10.1007/s43032-021-00729-6

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