6,028 Matching Annotations
  1. Feb 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice
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    1. scibot 04 Feb 2022
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      DOI: 10.1016/j.neuron.2022.01.006

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    sciencedirect.com/science/article/pii/S089662732200006X
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    Co-adaptor driven assembly of a CUL3 E3 ligase complex
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      DOI: 10.1016/j.molcel.2022.01.004

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    sciencedirect.com/science/article/pii/S1097276522000041
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    Mechanical phenotyping reveals unique biomechanical responses in retinoic acid-resistant acute promyelocytic leukemia
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      DOI: 10.1016/j.isci.2022.103772

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    sciencedirect.com/science/article/pii/S2589004222000426
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    A highly efficient stratagem for protoplast isolation and genetic transformation in filamentous fungus Colletotrichum falcatum
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    1. scibot 02 Feb 2022
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      DOI: 10.1007/s12223-022-00950-z

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    link.springer.com/article/10.1007/s12223-022-00950-z
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    Maternal diet-induced obesity during pregnancy alters lipid supply to mouse E18.5 fetuses and changes the cardiac tissue lipidome in a sex-dependent manner
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    1. scibot 02 Feb 2022
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      DOI: 10.7554/eLife.69078

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    ncbi.nlm.nih.gov/pmc/articles/PMC8794468/
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    A phosphoswitch at acinus-serine437 controls autophagic responses to cadmium exposure and neurodegenerative stress
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      DOI: 10.7554/eLife.72169

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    SoxD genes are required for adult neural stem cell activation
    1
    1. scibot 02 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110313

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    sciencedirect.com/science/article/pii/S2211124722000250
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    Proteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress
    1
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      DOI: 10.3389/fphar.2021.791097

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    Steroid hormone receptor and infiltrating immune cell status reveals therapeutic vulnerabilities of ESR1 mutant breast cancer.
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      DOI: 10.1158/0008-5472.CAN-20-1200

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    ncbi.nlm.nih.gov/pmc/articles/PMC7854521/
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    Gene silencing by EZH2 suppresses TGF-β activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface
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    sciencedirect.com/science/article/pii/S2211124722000456
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    Inhibition, but not excitation, recovers from partial cone loss with greater spatiotemporal integration, synapse density, and frequency
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    1. scibot 02 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110317

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    sciencedirect.com/science/article/pii/S2211124722000286
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    Gamma-Aminobutyric Acid Transporters in the Nucleus Tractus Solitarii Regulate Inhibitory and Excitatory Synaptic Currents That Influence Cardiorespiratory Function
    1
    1. scibot 01 Feb 2022
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      DOI: 10.3389/fphys.2021.821110

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  14. Jan 2022
  15. www.eneuro.org www.eneuro.org
    Extrafield Activity Shifts the Place Field Center of Mass to Encode Aversive Experience
    1
    1. scibot 29 Jan 2022
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      DOI: 10.1523/ENEURO.0423-17.2019

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    eneuro.org/content/6/2/ENEURO.0423-17.2019
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      DOI: 10.1111/bph.15524

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15524
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    Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing
    1
    1. scibot 29 Jan 2022
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      DOI: 10.1016/j.stem.2021.12.011

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    sciencedirect.com/science/article/pii/S1934590921005257
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic downregulation of neuronal PAS domain 2 (Npas2) promotes surgical skin wound healing
    1
    1. scibot 29 Jan 2022
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      DOI: 10.7554/eLife.71074

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    Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection
    1
    1. scibot 29 Jan 2022
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      DOI: 10.7554/eLife.73137

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    elifesciences.org/articles/73137
  20. www.futuremedicine.com www.futuremedicine.com
    Adipose tissue versus stem cell-derived small extracellular vesicles to enhance the healing of acute burns
    1
    1. scibot 28 Jan 2022
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      DOI: 10.2217/rme-2020-0199

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    futuremedicine.com/doi/abs/10.2217/rme-2020-0199
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Mlc1 Promoter Directs Müller Cell-specific Gene Expression in the Retina
    1
    1. scibot 28 Jan 2022
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      DOI: 10.1167/tvst.11.1.25

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    ncbi.nlm.nih.gov/pmc/articles/PMC8764212/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Visceral fat inflammation and fat embolism are associated with lung’s lipidic hyaline membranes in subjects with COVID-19
    1
    1. scibot 28 Jan 2022
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      DOI: 10.1038/s41366-022-01071-w

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  23. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 28 Jan 2022
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      DOI: 10.1111/bph.15773

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15773
  24. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Artemether and aspterric acid induce pancreatic α cells to transdifferentiate into β cells in zebrafish
    1
    1. scibot 28 Jan 2022
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      DOI: 10.1111/bph.15769

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15769
  25. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Amlodipine, an anti-hypertensive drug, alleviates non-alcoholic fatty liver disease by modulating gut microbiota
    1
    1. scibot 28 Jan 2022
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      DOI: 10.1111/bph.15768

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15768
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    1. scibot 28 Jan 2022
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      DOI: 10.1111/bph.15738

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    1. scibot 28 Jan 2022
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      DOI: 10.1111/bph.15722

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  28. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A new therapeutic effect of fenofibrate in Duchenne muscular dystrophy: The promotion of myostatin degradation
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      DOI: 10.1111/bph.15678

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  29. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive Channel Piezo1 Induces Cell Apoptosis in Pancreatic Cancer by Ultrasound with Microbubbles
    1
    1. scibot 27 Jan 2022
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      DOI: 10.1016/j.isci.2022.103733

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  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Progesterone receptor isoform ratio dictates antiprogestin/progestin effects on breast cancer growth and metastases: A role for NDRG1
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    1. scibot 27 Jan 2022
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      DOI: 10.1002/ijc.33913

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  31. www.sciencedirect.com www.sciencedirect.com
    The subthalamic corticotropin-releasing hormone neurons mediate adaptive REM-sleep responses to threat
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      DOI: 10.1016/j.neuron.2021.12.033

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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipocalin 2 Influences Bone and Muscle Phenotype in the MDX Mouse Model of Duchenne Muscular Dystrophy
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    1. scibot 26 Jan 2022
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      DOI: 10.3390/ijms23020958

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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylated α-tubulin K394 regulates microtubule stability to shape the growth of axon terminals
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      DOI: 10.1016/j.cub.2021.12.012

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    History-dependent dopamine release increases cAMP levels in most basal amygdala glutamatergic neurons to control learning
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      DOI: 10.1016/j.celrep.2022.110297

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    1. scibot 25 Jan 2022
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      DOI: 10.1111/bph.15730

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  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The altered osteocytic expression of connexin 43 and sclerostin in human cadaveric donors with alcoholic liver cirrhosis: Potential treatment targets
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      DOI: 10.1111/joa.13621

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  37. elifesciences.org elifesciences.org
    Cavefish cope with environmental hypoxia by developing more erythrocytes and overexpression of hypoxia-inducible genes
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      DOI: 10.7554/eLife.69109

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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brassinosteroids Mitigate Cadmium Effects in Arabidopsis Root System without Any Cooperation with Nitric Oxide
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      DOI: 10.3390/ijms23020825

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  39. elifesciences.org elifesciences.org
    Genetic basis and dual adaptive role of floral pigmentation in sunflowers
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      DOI: 10.7554/eLife.72072

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    Hepatic microRNA modulation might be an early event to non-alcoholic fatty liver disease development driven by high-fat diet in male mice
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      DOI: 10.1007/s11033-021-07072-8

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  41. www.sciencedirect.com www.sciencedirect.com
    Trigeminal ganglion and sensory nerves suggest tactile specialization of elephants
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      DOI: 10.1016/j.cub.2021.12.051

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    sciencedirect.com/science/article/pii/S0960982221017383
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wolframin-1–expressing neurons in the entorhinal cortex propagate tau to CA1 neurons and impair hippocampal memory in mice
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      DOI: 10.1126/scitranslmed.abe8455

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    ncbi.nlm.nih.gov/pmc/articles/PMC8763211/
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    Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism
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      DOI: 10.1016/j.xcrm.2021.100498

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    The influence of spontaneous and visual activity on the development of direction selectivity maps in mouse retina
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    Coronally Advanced Flap with Connective Tissue Graft for Treating Orthodontic-Associated Miller Class III Gingival Recession of the Lower Incisors: A One-Year Retrospective Study
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    Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome
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    Angiotensin II infusion results in both hypertension and increased AMPA GluA1 signaling in hypothalamic paraventricular nucleus of male but not female mice
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    Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors
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    Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia
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    Skeletal muscle phenotyping of Hippo gene-mutated mice reveals that Lats1 deletion increases the percentage of type I muscle fibers
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    Platelet rich plasma affects gap junctional features in myofibroblasts in vitro via Vascular Endothelial Growth Factor (VEGF)-A/VEGF receptor
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    Knockdown of Sexually Differentiated Vasopressin Expression in the Bed Nucleus of the Stria Terminalis Reduces Social and Sexual Behavior in Male, but Not Female, Mice
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    Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion
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    KIF5C deficiency causes abnormal cortical neuronal migration, dendritic branching, and spine morphology in mice
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    Compromised fractalkine signaling delays microglial occupancy of emerging modules in the multisensory midbrain
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    The Protective Mechanism of Deuterated Linoleic Acid Involves the Activation of the Ca2+ Signaling System of Astrocytes in Ischemia In Vitro
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    Conserved and divergent features of neuronal CaMKII holoenzyme structure, function, and high-order assembly
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    The ADAM17-directed Inhibitory Antibody MEDI3622 Antagonizes Radiotherapy-induced VEGF Release and Sensitizes Non–Small Cell Lung Cancer for RadiotherapyADAM17-mediated Radioresistance
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    A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo
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    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
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    Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice
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    Analgesic α-conotoxins modulate native and recombinant GIRK1/2 channels via GABAB receptor activation and reduce neuroexcitability
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    ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion
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    MicroRNA-193b impairs muscle growth in mouse models of type 2 diabetes by targeting the PDK1/Akt signalling pathway
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    Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
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    Impact of monomeric and aggregated wild-type and A30P/A53T double-mutant α-synuclein on antioxidant mechanism and glutamate metabolic profile of cultured astrocytes
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    Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease
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    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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    Pleiotropic vascular effects of ivabradine in streptozotocin-induced diabetes
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    KLF15 overexpression in myocytes fails to ameliorate ALS-related pathology or extend the lifespan of SOD1G93A mice
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    A recombinant protein containing influenza viral conserved epitopes and superantigen induces broad-spectrum protection
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    lncRNA BORG:TRIM28 Complexes Drive Metastatic Progression by Inducing α6 Integrin/CD49f Expression in Breast Cancer Stem Cells
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    TLR4 Associated Signaling Disrupters as a New Means to Overcome HERV-W Envelope-Mediated Myelination Deficits
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    The Mechanisms Underlying the Protective Action of Selenium Nanoparticles against Ischemia/Reoxygenation Are Mediated by the Activation of the Ca2+ Signaling System of Astrocytes and Reactive Astrogliosis
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    Coordinated repression of pro-differentiation genes via P-bodies and transcription maintains Drosophila intestinal stem cell identity
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    Knockdown of heterogeneous nuclear ribonucleoprotein A1 results in neurite damage, altered stress granule biology and cellular toxicity in differentiated neuronal cells
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    Association of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 With Angiotensin II Type 1 Receptor Impacts Mitochondrial Quality Control, Offering Promise for the Treatment of Vascular Senescence
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    Cell adhesion molecule L1 interacts with the chromo shadow domain of heterochromatin protein 1 isoforms α, β, and ɣ via its intracellular domain
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    Effects of Manipulation of Noradrenergic Activities on the Expression of Dopaminergic Phenotypes in Aged Rat Brains
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    Radium 223 treatment increase immune checkpoint expression in extracellular vesicles from the metastatic prostate cancer bone microenvironment
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    Proximity labeling identifies LOTUS domain proteins that promote the formation of perinuclear germ granules in C. elegans
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    p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts
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    The Immunoglobulin Superfamily Member Basigin Is Required for Complex Dendrite Formation in Drosophila
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    Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion
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    SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation
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    Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer
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  126. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phospholipase D and retromer promote recycling of TRPL ion channel via the endoplasmic reticulum
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    Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues
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    A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer
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    Chemical phenotypes of intrinsic cardiac neurons in the newborn pig (Sus scrofa domesticus Erxleben, 1777)
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    Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome
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    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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    Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
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    Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation
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    Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease
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    Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency
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    A pre-screening strategy to assess resected tumor margins by imaging cytoplasmic viscosity and hypoxia
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    Fibrinogen αC-subregions critically contribute blood clot fibre growth, mechanical stability and resistance to fibrinolysis
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    A Note of Caution: Gramicidin Affects Signaling Pathways Independently of Its Effects on Plasma Membrane Conductance
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    Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation of CREB at Serine 142 and 143 is essential for visual cortex plasticity
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    All-trans retinoic acid induces synaptopodin-dependent metaplasticity in mouse dentate granule cells
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    MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal
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    Long-term hypogonadism diminishes the neuroprotective effects of dietary genistein in young adult ovariectomized rats after transient focal ischemia
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    Ultrastructure of ipsilateral and contralateral tectopulvinar projections in the mouse
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    Deep Learning to Decipher the Progression and Morphology of Axonal Degeneration
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    A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
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    RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair
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    Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission
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    Optical Coherence Tomography Angiography Characteristics Serve as Retinal Vein Occlusion Therapeutic Biomarkers for Dexamethasone Intravitreal Implant
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    Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function
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    A Role for Translational Regulation by S6 Kinase and a Downstream Target in Inflammatory Pain
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    Plastin and spectrin cooperate to stabilize the actomyosin cortex during cytokinesis
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    Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast
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    Wolframin-1–expressing neurons in the entorhinal cortex propagate tau to CA1 neurons and impair hippocampal memory in mice
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    Protein Kinase D promotes activity-dependent AMPA receptor endocytosis in hippocampal neurons
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    Depichering the Effects of Astragaloside IV on AD-Like Phenotypes: A Systematic and Experimental Investigation
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