6,482 Matching Annotations
  1. May 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Corneal tissue-resident memory T cells form a unique immune compartment at the ocular surface
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    1. scibot 26 May 2022
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      DOI: 10.1016/j.celrep.2022.110852

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    sciencedirect.com/science/article/pii/S2211124722006258
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    BMAL1 modulates smooth muscle cells phenotypic switch towards fibroblast-like cells and stabilizes atherosclerotic plaques by upregulating YAP1
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      DOI: 10.1016/j.bbadis.2022.166450

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    sciencedirect.com/science/article/pii/S092544392200120X
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    Transcription factor Acj6 controls dendrite targeting via a combinatorial cell-surface code
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    1. scibot 25 May 2022
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      DOI: 10.1016/j.neuron.2022.04.026

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    sciencedirect.com/science/article/pii/S0896627322004032
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    Increased microtubule growth triggered by microvesicle-mediated paracrine signaling is required for melanoma cancer cell invasion
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    1. scibot 24 May 2022
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      DOI: 10.1158/2767-9764.CRC-22-0010

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    aacrjournals.org/cancerrescommun/article/2/5/366/698979/Increased-Microtubule-Growth-Triggered-by
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    Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model
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    1. scibot 24 May 2022
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      DOI: 10.7554/eLife.66037

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    ncbi.nlm.nih.gov/pmc/articles/PMC9122497/
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    DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells
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      DOI: 10.7554/eLife.74700

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    Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
    1
    1. scibot 21 May 2022
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      DOI: 10.7554/eLife.77696

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    ncbi.nlm.nih.gov/pmc/articles/PMC9113749/
  9. www.eneuro.org www.eneuro.org
    Bisphenol A Exposure Induces Sensory Processing Deficits in Larval Zebrafish During Neurodevelopment
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      DOI: 10.1523/ENEURO.0020-22.2022

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    Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense
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    1. scibot 21 May 2022
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      DOI: 10.7554/eLife.73625

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  11. www.researchsquare.com www.researchsquare.com
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      DOI: 10.21203/rs.3.rs-658360/v1

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    The Taspase1/Myosin1f-axis regulates filopodia dynamics
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      DOI: 10.1016/j.isci.2022.104355

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    sciencedirect.com/science/article/pii/S2589004222006265
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    Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo
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    1. scibot 19 May 2022
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      DOI: 10.1016/j.xcrm.2022.100630

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    The regulating pathway of creatine on muscular protein metabolism depends on the energy state
    1
    1. scibot 19 May 2022
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      DOI: 10.1152/ajpcell.00447.2021

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    journals.physiology.org/doi/full/10.1152/ajpcell.00447.2021
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    Secretion of interleukin-1 by dedifferentiated melanoma cells inhibits JAK1-STAT3-driven actomyosin contractility of lymph node fibroblastic reticular cells
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    1. scibot 19 May 2022
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      DOI: 10.1158/0008-5472.CAN-21-0501

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    aacrjournals.org/cancerres/article/82/9/1774/694699/Secretion-of-IL1-by-Dedifferentiated-Melanoma
  16. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.15856

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15856
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    Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition
    1
    1. scibot 19 May 2022
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      DOI: 10.1186/s12915-022-01312-4

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  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zebrafish airinemes optimize their shape between ballistic and diffusive search
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    1. scibot 18 May 2022
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      DOI: 10.7554/eLife.75690

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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VE-cadherin enables trophoblast endovascular invasion and spiral artery remodeling during placental development
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      DOI: 10.7554/eLife.77241

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  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic variation in ALDH4A1 is associated with muscle health over the lifespan and across species
    1
    1. scibot 18 May 2022
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      DOI: 10.7554/eLife.74308

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    ncbi.nlm.nih.gov/pmc/articles/PMC9106327/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL13Rα2 promotes proliferation and outgrowth of breast cancer brain metastases
    1
    1. scibot 18 May 2022
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      DOI: 10.1158/1078-0432.CCR-21-0361

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    ncbi.nlm.nih.gov/pmc/articles/PMC8595859/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Matricellular protein WISP2 is an endogenous inhibitor of collagen linearization and cancer metastasis
    1
    1. scibot 18 May 2022
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      DOI: 10.1158/0008-5472.CAN-20-3982

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    ncbi.nlm.nih.gov/pmc/articles/PMC8595651/
  23. 52.53.155.43 52.53.155.43
    Ym1+ macrophages orchestrate fibrosis, lesion growth and progression during development of murine pancreatic cancer
    1
    1. scibot 18 May 2022
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      DOI: 10.1016/j.isci.2022.104327

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    Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model
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    1. scibot 18 May 2022
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      DOI: 10.1016/j.isci.2022.104334

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    sciencedirect.com/science/article/pii/S2589004222006058
  25. aacrjournals.org aacrjournals.org
    Proteolytic pan-RAS cleavage leads to tumor regression in patient-derived pancreatic cancer xenografts
    1
    1. scibot 14 May 2022
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      DOI: 10.1158/1535-7163.MCT-21-0550

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    aacrjournals.org/mct/article/21/5/810/694769/Proteolytic-pan-RAS-Cleavage-Leads-to-Tumor
  26. aacrjournals.org aacrjournals.org
    Triple targeting of HER receptors overcomes heregulin-mediated resistance to EGFR blockade in colorectal cancer
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      DOI: 10.1158/1535-7163.MCT-21-0818

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    aacrjournals.org/mct/article/21/5/799/694777/Triple-Targeting-of-HER-Receptors-Overcomes
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glutamate–aspartate transporter 1 attenuates oxygen–glucose deprivation-induced injury by promoting glutamate metabolism in primary cortical neurons
    1
    1. scibot 14 May 2022
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      DOI: 10.1002/jcp.30768

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    onlinelibrary.wiley.com/doi/10.1002/jcp.30768
  28. aacrjournals.org aacrjournals.org
    EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion-positive cholangiocarcinoma
    1
    1. scibot 13 May 2022
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      DOI: 10.1158/2159-8290.CD-21-1168

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    aacrjournals.org/cancerdiscovery/article/12/5/1378/694560/EGFR-Inhibition-Potentiates-FGFR-Inhibitor-Therapy
  29. aacrjournals.org aacrjournals.org
    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
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    1. scibot 13 May 2022
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      DOI: 10.1158/2159-8290.CD-21-1006

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    aacrjournals.org/cancerdiscovery/article/12/5/1314/694563/Melanoma-Secreted-Amyloid-Beta-Suppresses
  30. aacrjournals.org aacrjournals.org
    Tumor ENPP1(CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
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    1. scibot 13 May 2022
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      DOI: 10.1158/2159-8290.CD-21-0932

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    aacrjournals.org/cancerdiscovery/article/12/5/1356/694562/Tumor-ENPP1-CD203a-Haptoglobin-Axis-Exploits
  31. aacrjournals.org aacrjournals.org
    Tumor Microenvironment Acidity Triggers Lipid Accumulation in Liver Cancer via SCD1 Activation
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      DOI: 10.1158/1541-7786.MCR-21-0699

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    aacrjournals.org/mcr/article/20/5/810/694642/Tumor-Microenvironment-Acidity-Triggers-Lipid
  32. www.sciencedirect.com www.sciencedirect.com
    Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
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      DOI: 10.1016/j.celrep.2022.110790

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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dithiothreitol causes toxicity in C. elegans by modulating the methionine–homocysteine cycle
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      DOI: 10.7554/eLife.76021

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    ncbi.nlm.nih.gov/pmc/articles/PMC9090326/
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    Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis
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      DOI: 10.1016/j.celrep.2022.110761

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    Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation
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      DOI: 10.1007/s00109-022-02202-6

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    link.springer.com/article/10.1007/s00109-022-02202-6
  36. www.sciencedirect.com www.sciencedirect.com
    Targeted proteoform mapping uncovers specific Neurexin-3 variants required for dendritic inhibition
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      DOI: 10.1016/j.neuron.2022.04.017

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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity
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      DOI: 10.1126/sciadv.abn0044

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    ncbi.nlm.nih.gov/pmc/articles/PMC9054026/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysfunction of Inflammatory Pathways and Their Relationship With Psychological Factors in Adult Female Patients With Eating Disorders
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      DOI: 10.3389/fphar.2022.846172

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    ncbi.nlm.nih.gov/pmc/articles/PMC9062031/
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    Characterization of convergent thickening, a major convergence force producing morphogenic movement in amphibians
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      DOI: 10.7554/eLife.57642

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    ncbi.nlm.nih.gov/pmc/articles/PMC9064293/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cold protection allows local cryotherapy in a clinical-relevant model of traumatic optic neuropathy
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      DOI: 10.7554/eLife.75070

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    Andrographolide, isolated from Andrographis paniculata , induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production
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      DOI: 10.12688/f1000research.53595.2

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    Enhanced C/EBPβ function promotes hypertrophic versus hyperplastic fat tissue growth and prevents steatosis in response to high-fat diet feeding
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    Improved Characteristics of RANKL Immuno-PET Imaging Using Radiolabeled Antibody Fab Fragments
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    Differentiation of Livestock Internal Organs Using Visible and Short-Wave Infrared Hyperspectral Imaging Sensors
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    Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment
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    A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity
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    FILIP1L loss is a driver of aggressive mucinous colorectal adenocarcinoma and mediates cytokinesis defects through PFDN1
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    Acute axon damage and demyelination are mitigated by 4-aminopyridine (4-AP) therapy after experimental traumatic brain injury
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    Differential activation of pain circuitry neuron populations in a mouse model of spinal cord injury induced neuropathic pain
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    Manipulation of the miR-378a/mt-ATP6 regulatory axis rescues ATP synthase in the diabetic heart and offers a novel role for lncRNA Kcnq1ot1
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    Intensity distribution segmentation in ultrafast Doppler combined with scanning laser confocal microscopy for assessing vascular changes associated with ageing in murine hippocampi
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    TNF Signaling Acts Downstream of MiR-322/-503 in Regulating DM1 Myogenesis
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    Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice
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    Paradoxical effects of posterior intralaminar thalamic calretinin neurons on hippocampal seizure via distinct downstream circuits
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    Bladder epithelial cell phosphate transporter inhibition protects mice against uropathogenic Escherichia coli infection
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    Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques
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    Plasticity of neural connections underlying oxytocin-mediated parental behaviors of male mice
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    AraC-FdUMP[10] Is a Next-Generation Fluoropyrimidine with Potent Antitumor Activity in PDAC and Synergy with PARG Inhibition
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    A Foxo1-Klf2-S1pr1-Gnai1-Rac1 signaling axis is a critical mediator of Ostm1 regulatory network in T-lymphopoiesis
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    Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region
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    Patient-derived anti-NMDAR antibody disinhibits cortical neuronal networks through dysfunction of inhibitory neuron output
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    Protective role of casuarinin from Melastoma malabathricum against a mouse model of 5-fluorouracil–induced intestinal mucositis: impact on inflammation and gut microbiota dysbiosis
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    IMPACT OF TWO DIFFERENT TYPES OF EXERCISE TRAINING IMPACT ON AMPH ADDICTION: ROLE OF HIPPOCAMPAL NEUROTROPHINS
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    SALSA, a genetically encoded biosensor for spatiotemporal quantification of Notch signal transduction in vivo
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    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
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    Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1 mutant mice
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    The topography of corticopontine projections is controlled by postmitotic expression of the area-mapping gene Nr2f1
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    The Cell Adhesion Molecule L1 Interacts with Methyl CpG Binding Protein 2 via Its Intracellular Domain
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    Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease
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    Stromal HIF2 Regulates Immune Suppression in the Pancreatic Cancer Microenvironment
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    Distinct inhibitory pathways control velocity and directional tuning in the mouse retina
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    Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease
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    Sesquiterpenoids isolated from davana (Artemisia pallens Wall. ex DC) mitigates parkinsonism in Caenorhabditis elegans disease model
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    POSH regulates assembly of the NMDAR/PSD-95/Shank complex and synaptic function
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    Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
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    Direct vascular contact is a hallmark of cerebral astrocytes
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    Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia
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    Chk1 Inhibition Potently Blocks STAT3 Tyrosine705 Phosphorylation, DNA-Binding Activity, and Activation of Downstream Targets in Human Multiple Myeloma Cells
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    Impact of Non-pharmacological Chronic Hypertension on a Transgenic Rat Model of Cerebral Amyloid Angiopathy
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    VGLUT3 gates psychomotor effects induced by amphetamine
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    G protein-coupled estrogen receptor activates cell type-specific signaling pathways in cortical cultures: relevance to the selective loss of astrocytes
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    Neuronal F-Box protein FBXO41 regulates synaptic transmission and hippocampal network maturation
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    A series of xanthenes inhibiting Rad6 function and Rad6–Rad18 interaction in the PCNA ubiquitination cascade
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    Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells
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    Tunneling Nanotube-Mediated Mitochondrial Transfer Rescues Nucleus Pulposus Cells from Mitochondrial Dysfunction and Apoptosis
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    Cerebrospinal fluid of progressive multiple sclerosis patients reduces differentiation and immune functions of oligodendrocyte progenitor cells
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    Reprogramming bone progenitor identity and potency through control of collagen density and oxygen tension
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    Exploration of the niche effect on tumor satellite budding of head and neck cancer with biomimicking modeling
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    In Search for the Avian Trigeminal Magnetic Sensor: Distribution of Peripheral and Central Terminals of Ophthalmic Sensory Neurons in the Night-Migratory Eurasian Blackcap (Sylvia atricapilla)
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    Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer
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    Gasdermin D serves as a key executioner of pyroptosis in experimental cerebral ischemia and reperfusion model both in vivo and in vitro
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    Injury to hypothalamic Sim1 neurons is a common feature of obesity by exposure to high-fat diet in male and female mice
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    Novel cellular mechanism that mediates the collecting duct formation during postnatal renal development
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    Chronic immobilization stress primes the hippocampal opioid system for oxycodone-associated learning in female but not male rats
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    Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation
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    Evaluation of Hydroxycarboxylic Acid Receptor 1 (HCAR1) as a Building Block for Genetically Encoded Extracellular Lactate Biosensors
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    Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication
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    Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1G93A mice
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    Human umbilical artery endothelial cells from Large-for-Gestational-Age newborn have increased antioxidant efficiency and gene expression
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    Increasing carbohydrate availability in the hindgut promotes hypothalamic neurotransmitter synthesis: aromatic amino acids linking the microbiota–brain axis
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    Leptomeningeal anastomosis and early ischemic lesions on diffusion-weighted imaging in male murine focal cerebral ischemia
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    Modulation of renin angiotensin system components by high glucose levels in the culture of collecting duct cells
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    Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression
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    Tadr is an axonal histidine transporter required for visual neurotransmission in Drosophila
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    Tunneling Nanotube-Mediated Mitochondrial Transfer Rescues Nucleus Pulposus Cells from Mitochondrial Dysfunction and Apoptosis
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  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astrocyte-secreted chordin-like 1 regulates spine density after ischemic injury
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reactive Oxygen Species Cause Exercise-Induced Angina in a Myocardial Ischaemia-Reperfusion Injury Model
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    Laser microscopy acquisition and analysis of premotor synapses in the murine spinal cord
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    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temperature evolution following joint loading promotes chondrogenesis by synergistic cues via calcium signaling
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    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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    Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue - Marc Briquet, Anne-Bérengère Rocher, Maxime Alessandri, Nadia Rosenberg, Haissa de Castro Abrantes, Joel Wellbourne-Wood, Céline Schmuziger, Vanessa Ginet, Julien Puyal, Etienne Pralong, Roy Thomas Daniel, Stefan Offermanns, Jean-Yves Chatton, 2022
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    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
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    5-HT3Rs Maintain Hippocampal LTP in a CB1R-GABAA-Dependent Manner for Spatial Memory
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