836 Matching Annotations
  1. Sep 2024
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    Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance
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    Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA
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    sciencedirect.com/science/article/pii/S2211124720309244
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    Protein UFMylation regulates early events during ribosomal DNA-damage response
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    sciencedirect.com/science/article/pii/S2211124724010891
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    m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1
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    sciencedirect.com/science/article/pii/S1550413124003334
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    Targeting APT2 improves MAVS palmitoylation and antiviral innate immunity
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    Beyond mitochondrial transfer, cell fusion rescues metabolic dysfunction and boosts malignancy in adenoid cystic carcinoma
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  8. Aug 2024
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    On the role of p53 in the cellular response to aneuploidy
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    Phosphoglycerate kinase is a central leverage point in Parkinson’s disease–driven neuronal metabolic deficits
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    Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries
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    Physical exercise mediates cortical synaptic protein lactylation to improve stress resilience
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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    Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT
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    SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
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    The BET PROTAC inhibitor GNE-987 displays anti-tumor effects by targeting super-enhancers regulated gene in osteosarcoma
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    EZH2 as a major histone methyltransferase in PDGF-BB-activated orbital fibroblast in the pathogenesis of Graves’ ophthalmopathy
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    First Compound Heterozygous Mutations of DMP1 Causing Rare Autosomal Recessive Hypophosphatemic Rickets Type 1
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    RIPK1 Promotes Energy Sensing by the mTORC1 Pathway
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  21. Jul 2024
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    A Comprehensive Protocol for Efficient Differentiation of Human NPCs into Electrically Competent Neurons
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    MicroRNA-19b exacerbates systemic sclerosis through promoting Th9 cells
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    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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    Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling
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    Analyzing embryo dormancy at single-cell resolution reveals dynamic transcriptional responses and activation of integrin-Yap/Taz prosurvival signaling
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    Melatonin alleviates high-fat-diet-induced dry eye by regulating macrophage polarization via IFT27 and lowering ERK/JNK phosphorylation
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    The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway
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    Increased regional activity of a pro-autophagy pathway in schizophrenia as a contributor to sex differences in the disease pathology
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    CCR3 knockdown attenuates prolonged underwater operations-induced cognitive impairment via alleviating microglia-mediated neuroinflammation
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    Synthetic lethal CRISPR screen identifies a cancer cell-intrinsic role of PD-L1 in regulation of vulnerability to ferroptosis
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    Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis
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    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease
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    Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes
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  41. Jun 2024
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    Obg-like ATPase 1 exacerbated gemcitabine drug resistance of pancreatic cancer
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    Hypoxia-induced CTCF promotes EMT in breast cancer
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    PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer
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    Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer
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    Circ_0007432 promotes non-small cell lung cancer progression and macrophage M2 polarization through SRSF1/KLF12 axis
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    DDX56 promotes EMT and cancer stemness via MELK-FOXM1 axis in hepatocellular carcinoma
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    Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule
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    ATG16L1 induces the formation of phagophore-like membrane cups
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    Cardioprotective effect of Cinnamamide derivative compound 10 against myocardial ischemia-reperfusion through regulating cardiac autophagy via Sirt1
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  51. May 2024
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    Analyzing efficiency of a lentiviral shRNA knockdown system in human enteroids using western blot and flow cytometry
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    CRACD loss induces neuroendocrine cell plasticity of lung adenocarcinoma
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    Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A10
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    Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A10
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    Repurposing homoharringtonine for thyroid cancer treatment through TIMP1/FAK/PI3K/AKT signaling pathway
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    Characterization of a novel HDAC2 pathogenetic variant: a missing puzzle piece for chromatinopathies
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    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
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    The adipose-neural axis is involved in epicardial adipose tissue-related cardiac arrhythmias
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    Local glycolysis fuels actomyosin contraction during axonal retraction
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    Hepatokine ITIH3 Protects Against Hepatic Steatosis by Downregulating Mitochondrial Bioenergetics and De Novo Lipogenesis
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    Septin 7 interacts with Numb to preserve sarcomere structural organization and muscle contractile function
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    Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
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    Dynamic role of CUL4B in radiation-induced intestinal injury-regeneration
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    Epstein–Barr Virus BALF0/1 Subverts the Caveolin and ERAD Pathways to Target B-cell Receptor Complexes for Degradation
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    Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma
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    RGD Targeted Magnetic Ferrite Nanoparticles Enhance Antitumor Immunotherapeutic Efficacy by Activating STING Signaling Pathway
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  71. Apr 2024
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    Standardized In Vitro Models of Human Adipose Tissue Reveal Metabolic Flexibility in Brown Adipocyte Thermogenesis
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    Semaphorin3C identified as mediator of neuroinflammation and microglia polarization after spinal cord injury
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    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
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    DNA-PK and ATM drive phosphorylation signatures that antagonistically regulate cytokine responses to herpesvirus infection or DNA damage
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    Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors
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    Chemically engineered mTOR-nanoparticle blockers enhance antitumour efficacy
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    Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in mammals
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    Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis
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    Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum
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    Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain
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    Sexual Dimorphism of Circadian Liver Transcriptome.
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  86. Mar 2024
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    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
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    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
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    Light-mediated intracellular polymerization
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    Angiotensin II type-2 receptor signaling facilitates liver injury repair and regeneration via inactivation of Hippo pathway
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    Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor
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    Housekeeping U1 snRNA facilitates antiviral innate immunity by promoting TRIM25-mediated RIG-I activation
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    Combinatorial selective ER-phagy remodels the ER during neurogenesis
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