647 Matching Annotations
  1. Jun 2023
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ca2+-dependent activator protein for secretion 1 promotes spontaneous recovery in ischemic stroke by regulating BDNF secretion
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1111/jnc.15808

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15808
  3. May 2023
  4. www.sciencedirect.com www.sciencedirect.com
    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
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    1. scibot 31 May 2023
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      DOI: 10.1016/j.molcel.2023.05.011

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    sciencedirect.com/science/article/pii/S1097276523003350
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells
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    1. scibot 27 May 2023
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      DOI: 10.1016/j.isci.2023.106827

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    ncbi.nlm.nih.gov/pmc/articles/PMC10209538/
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    Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis
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    1. scibot 24 May 2023
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      DOI: 10.1016/j.celrep.2023.112550

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    sciencedirect.com/science/article/pii/S2211124723005612
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    ATROPHIC REMODELING OF THE HEART DURING VITAMIN D DEFICIENCY AND INSUFFICIENCY IN A RAT MODEL
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    1. scibot 20 May 2023
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      DOI: 10.1016/j.jnutbio.2023.109382

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    sciencedirect.com/science/article/pii/S0955286323001158
  8. link.springer.com link.springer.com
    Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity
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    1. scibot 18 May 2023
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      DOI: 10.1038/s41598-023-33924-3

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    link.springer.com/article/10.1038/s41598-023-33924-3
  9. www.science.org www.science.org
    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
    1
    1. scibot 18 May 2023
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      DOI: 10.1126/sciadv.add8023

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    science.org/doi/10.1126/sciadv.add8023
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    MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis
    1
    1. scibot 18 May 2023
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      DOI: 10.1016/j.isci.2023.106770

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    sciencedirect.com/science/article/pii/S2589004223008477
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    Heat promotes melanogenesis by increasing the paracrine effects in keratinocytes via the TRPV3/Ca2+/Hh signaling pathway
    1
    1. scibot 14 May 2023
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      DOI: 10.1016/j.isci.2023.106749

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    sciencedirect.com/science/article/pii/S258900422300826X
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
    1
    1. scibot 12 May 2023
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      DOI: 10.1126/sciadv.add8023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10171824/
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    Vitamin K-dependent carboxylation regulates Ca2+ flux and adaptation to metabolic stress in β cells
    1
    1. scibot 12 May 2023
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      DOI: 10.1016/j.celrep.2023.112500

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    sciencedirect.com/science/article/pii/S2211124723005119
  14. 52.53.155.43 52.53.155.43
    Opioid growth factor receptor promotes adipose tissue thermogenesis via enhancing lipid oxidation
    1
    1. scibot 11 May 2023
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      DOI: 10.1093/lifemeta/load018

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    A nanotherapeutic strategy that engages cytotoxic and immunosuppressive activities for the treatment of cancer recurrence following organ transplantation
    1
    1. scibot 10 May 2023
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      DOI: 10.1016/j.ebiom.2023.104594

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    sciencedirect.com/science/article/pii/S2352396423001597
  16. www.sciencedirect.com www.sciencedirect.com
    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
    1
    1. scibot 05 May 2023
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      DOI: 10.1016/j.ebiom.2022.104155

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    sciencedirect.com/science/article/pii/S235239642200336X
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    Exercise-derived peptide protects against pathological cardiac remodeling
    1
    1. scibot 05 May 2023
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      DOI: 10.1016/j.ebiom.2022.104164

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    sciencedirect.com/science/article/pii/S2352396422003450
  18. Apr 2023
  19. www.sciencedirect.com www.sciencedirect.com
    ZFP36-mediated mRNA decay regulates metabolism
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112411

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    sciencedirect.com/science/article/pii/S2211124723004229
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    Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways
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      DOI: 10.1016/j.celrep.2023.112434

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    sciencedirect.com/science/article/pii/S221112472300445X
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    AKT activity orchestrates marginal zone B cell development in mice and humans
    1
    1. scibot 15 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112378

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    sciencedirect.com/science/article/pii/S2211124723003893
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitoxantrone and Mitoxantrone-Loaded Iron Oxide Nanoparticles Induce Cell Death in Human Pancreatic Ductal Adenocarcinoma Cell Spheroids
    1
    1. scibot 14 Apr 2023
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      DOI: 10.3390/ma16072906

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    ncbi.nlm.nih.gov/pmc/articles/PMC10096321/
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    Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development
    1
    1. scibot 13 Apr 2023
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      DOI: 10.1016/j.devcel.2023.03.016

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    sciencedirect.com/science/article/pii/S1534580723001326
  24. link.springer.com link.springer.com
    N,N-Dimethyl-3β-hydroxycholenamide attenuates neuronal death and retinal inflammation in retinal ischemia/reperfusion injury by inhibiting Ninjurin 1
    1
    1. scibot 11 Apr 2023
      RRID:AB_10622025

      DOI: 10.1186/s12974-023-02754-5

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    link.springer.com/article/10.1186/s12974-023-02754-5
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adiponectin-mediated promotion of CD44 suppresses diabetic vascular inflammatory effects
    1
    1. scibot 09 Apr 2023
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      DOI: 10.1016/j.isci.2023.106428

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    ncbi.nlm.nih.gov/pmc/articles/PMC10067764/
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    Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation
    1
    1. scibot 07 Apr 2023
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      DOI: 10.1016/j.stem.2023.03.005

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    sciencedirect.com/science/article/pii/S1934590923000760
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    Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance
    1
    1. scibot 06 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112314

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    sciencedirect.com/science/article/pii/S221112472300325X
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphate Depletion in Insulin-Insensitive Skeletal Muscle Drives AMPD Activation and Sarcopenia in Chronic Kidney DIsease
    1
    1. scibot 05 Apr 2023
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      DOI: 10.1016/j.isci.2023.106355

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    ncbi.nlm.nih.gov/pmc/articles/PMC10040733/
  29. Mar 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
    1
    1. scibot 30 Mar 2023
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      DOI: 10.1016/j.isci.2023.106410

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    sciencedirect.com/science/article/pii/S258900422300487X
  31. www.sciencedirect.com www.sciencedirect.com
    The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus
    1
    1. scibot 28 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112306

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    sciencedirect.com/science/article/pii/S2211124723003170
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes
    1
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      DOI: 10.3389/fphar.2023.1094584

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    ncbi.nlm.nih.gov/pmc/articles/PMC10027750/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model
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      DOI: 10.1016/j.isci.2023.106270

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    ncbi.nlm.nih.gov/pmc/articles/PMC10014277/
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    VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma
    1
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      DOI: 10.1007/s13402-023-00793-x

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    link.springer.com/article/10.1007/s13402-023-00793-x
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids
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      DOI: 10.3389/fimmu.2023.1097383

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    ncbi.nlm.nih.gov/pmc/articles/PMC9995983/
  36. 52.53.155.43 52.53.155.43
    Inhibiting tau protein improves the recovery of spinal cord ... : Neural Regeneration Research
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      DOI: 10.4103/1673-5374.363183

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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone malonylation is regulated by SIRT5 and KAT2A
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      DOI: 10.1016/j.isci.2023.106193

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    ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
  38. link.springer.com link.springer.com
    Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons
    1
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      DOI: 10.1007/s12035-023-03281-3

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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
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      DOI: 10.1158/2159-8290.CD-22-0424

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  40. Feb 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Coumarin-derived imino sulfonate 5h ameliorates cardiac injury induced by myocardial infarction via activating the Sirt1/Nrf2 signaling pathway
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      DOI: 10.1016/j.ejphar.2023.175615

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    sciencedirect.com/science/article/pii/S0014299923001267
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    Aberrant serotonergic signaling contributes to the hyperexcitability of CA1 pyramidal neurons in a mouse model of Alzheimer’s disease
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      DOI: 10.1016/j.celrep.2023.112152

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    sciencedirect.com/science/article/pii/S2211124723001638
  43. aacrjournals.org aacrjournals.org
    HRS regulates small extracellular vesicle PD-L1 secretion and is associated with anti-PD-1 treatment efficacy
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      DOI: 10.1158/2326-6066.CIR-22-0277

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    aacrjournals.org/cancerimmunolres/article/11/2/228/716209/HRS-Regulates-Small-Extracellular-Vesicle-PD-L1
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    HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8+T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma
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      DOI: 10.1016/j.isci.2023.106143

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  87. Sep 2022
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single cell RNA-seq analysis identifies ferroptotic chondrocyte cluster and reveals TRPV1 as an anti-ferroptotic target in osteoarthritis
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    Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin
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    Ceramide induces macrophage migration inhibitory factor -mediated parthanatos in mouse neurons by increasing ROS levels
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    Activation of cGAS-STING pathway – A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy
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    Methionine metabolism controls the B cell EBV epigenome and viral latency
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    Virtual screening for small-molecule pathway regulators by image-profile matching
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    CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair
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    Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia
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    Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development
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    Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition
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    A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
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    GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming
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    Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis
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    Identification of a Novel Axon Regeneration Role for Non-Canonical Wnt Signaling in the Adult Retina After Injury
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    Neuroinflammatory disease disrupts the blood-CNS barrier via crosstalk between proinflammatory and endothelial-to-mesenchymal-transition signaling
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    Ras Inhibitor Lonafarnib Rescues Structural and Functional Impairments of Synapses of Aβ1-42 Mice via α7nAChR-Dependent BDNF Upregulation
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    Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment
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  106. Jul 2022
  107. aacrjournals.org aacrjournals.org
    Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer
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    Arginine Methyltransferase Carm1 is Necessary for Heart Development
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    Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis
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    Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer
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  115. Jun 2022
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    Loss of low molecular weight protein tyrosine phosphatase (LMPTP) shows limited improvement in glucose tolerance but causes mild cardiac hypertrophy in mice
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    Loss of low-molecular-weight protein tyrosine phosphatase shows limited improvement in glucose tolerance but causes mild cardiac hypertrophy in mice
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    Ym1+ macrophages orchestrate fibrosis, lesion growth and progression during development of murine pancreatic cancer
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    NR2F1 is a barrier to dissemination of early stage breast cancer cells.
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    Signaling pathways involved in NMDA-induced suppression of M-channels in corticotropin-releasing hormone neurons in central amygdala
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  123. May 2022
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    Ym1+ macrophages orchestrate fibrosis, lesion growth and progression during development of murine pancreatic cancer
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  126. Apr 2022
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    Downregulation of microRNA-124-3p promotes subventricular zone neural stem cell activation by enhancing the function of BDNF downstream pathways after traumatic brain injury in adult rats
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    Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB
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    L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy
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    VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites
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    Ebselen prevents cigarette smoke-induced cognitive dysfunction in mice by preserving hippocampal synaptophysin expression
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    Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection
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    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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    Hypermethylation of miR-145 promoter-mediated SOX9-CLDN8 pathway regulates intestinal mucosal barrier in Crohn's disease
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  164. cancerimmunolres.aacrjournals.org cancerimmunolres.aacrjournals.org
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  174. Nov 2021
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    Maternal iron deficiency alters trophoblast differentiation and placental development in rat pregnancy
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    Non-canonical protease-activated receptor 1 regulates lymphatic differentiation in zebrafish
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    Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism
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    Integrated genomic and proteomic analyses identify stimulus-dependent molecular changes associated with distinct modes of skeletal muscle atrophy
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    A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors
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    A novel jamming phase diagram links tumor invasion to non-equilibrium phase separation
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    Merkel cell polyomavirus T-antigens regulate DICER1 mRNA stability and translation through HSC70
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    MiR-552-3p promotes malignant progression of gallbladder carcinoma by reactivating the Akt/β-catenin signaling pathway due to inhibition of the tumor suppressor gene RGMA
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  184. Oct 2021
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    Hsa_circ_0023990 promotes tumor growth and glycolysis in dedifferentiated TC via targeting miR-485-5p/FOXM1 axis
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    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms
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    Wolfberry-derived zeaxanthin dipalmitate delays retinal degeneration in a mouse model of retinitis pigmentosa through modulating STAT3, CCL2 and MAPK pathways
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    Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome
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    Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension
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    In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
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    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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    A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells
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    CXCL10/CXCR3 signaling contributes to an inflammatory microenvironment and its blockade enhances progression of murine pancreatic precancerous lesions
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    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
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    Transgenic modeling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function
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    The Presynaptic Scaffold Protein Bassoon in Forebrain Excitatory Neurons Mediates Hippocampal Circuit Maturation: Potential Involvement of TrkB Signalling
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    Severe deficiency of the voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice
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    BCAA Supplementation in Mice with Diet-Induced Obesity Alters the Metabolome Without Impairing Glucose Homeostasis
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    RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal
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  216. elifesciences.org elifesciences.org
    GIPC proteins negatively modulate Plexind1 signaling during vascular development
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      DOI: 10.7554/eLife.30454

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  217. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1096/fj.201802167R

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