319 Matching Annotations
  1. Oct 2021
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment
    1
    1. scibot 08 Oct 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cell.2021.09.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC8650838/
  3. www.sciencedirect.com www.sciencedirect.com
    Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza
    1
    1. scibot 06 Oct 2021
      RRID:AB_1107769

      DOI: 10.1016/j.isci.2021.103131

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    sciencedirect.com/science/article/pii/S2589004221010993
  4. Sep 2021
  5. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
    1
    1. scibot 28 Sep 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cell.2021.09.006

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    sciencedirect.com/science/article/pii/S0092867421010539
  6. link.springer.com link.springer.com
    The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides
    1
    1. scibot 21 Sep 2021
      RRID:AB_1107769

      DOI: 10.1007/s00262-021-03051-x

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    link.springer.com/article/10.1007/s00262-021-03051-x
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell
    1
    1. scibot 18 Sep 2021
      RRID:AB_1107769

      DOI: 10.1136/jitc-2021-003100

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    ncbi.nlm.nih.gov/pmc/articles/PMC8407215/
  8. www.sciencedirect.com www.sciencedirect.com
    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
    1
    1. scibot 18 Sep 2021
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      DOI: 10.1016/j.cell.2021.08.020

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    sciencedirect.com/science/article/pii/S0092867421009946
  9. www.sciencedirect.com www.sciencedirect.com
    Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma
    1
    1. scibot 15 Sep 2021
      RRID:AB_1107769

      DOI: 10.1016/j.xcrm.2021.100399

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    sciencedirect.com/science/article/pii/S2666379121002573
  10. www.sciencedirect.com www.sciencedirect.com
    Effects of exercise and anti-PD-1 on the tumour microenvironment
    1
    1. scibot 08 Sep 2021
      RRID:AB_1

      DOI: 10.1016/j.imlet.2021.08.005

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      Curator comments: InVivoMab rat IgG2a isotype control antibody Bio X Cell Cat# BE0089

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    sciencedirect.com/science/article/abs/pii/S0165247821001401
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer
    1
    1. scibot 04 Sep 2021
      RRID:AB_1107769

      DOI: 10.2147/OTT.S326178

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    ncbi.nlm.nih.gov/pmc/articles/PMC8403083/
  12. Aug 2021
  13. www.sciencedirect.com www.sciencedirect.com
    Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
    1
    1. scibot 28 Aug 2021
      RRID:AB_1107769

      DOI: 10.1016/j.chom.2021.08.001

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    sciencedirect.com/science/article/pii/S1931312821003772
  14. www.sciencedirect.com www.sciencedirect.com
    Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy
    1
    1. scibot 25 Aug 2021
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2021.109578

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    sciencedirect.com/science/article/pii/S2211124721010123
  15. www.sciencedirect.com www.sciencedirect.com
    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
    1
    1. scibot 15 Aug 2021
      AB_1107769

      DOI: 10.1016/j.celrep.2021.109516

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    sciencedirect.com/science/article/pii/S2211124721009463
  16. www.sciencedirect.com www.sciencedirect.com
    The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
    1
    1. scibot 15 Aug 2021
      RRID:AB_1107769

      DOI: 10.1016/j.ccell.2021.07.007

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    sciencedirect.com/science/article/pii/S1535610821003846
  17. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 09 Aug 2021
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2018.11.047

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    sciencedirect.com/science/article/pii/S2211124718318102
  18. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 09 Aug 2021
      RRID:AB_1107769

      DOI: 10.1016/j.immuni.2018.10.007

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    sciencedirect.com/science/article/pii/S1074761318304485
  19. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 09 Aug 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cell.2018.10.014

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    sciencedirect.com/science/article/pii/S0092867418313229
  20. www.sciencedirect.com www.sciencedirect.com
    Persistence of Systemic Murine Norovirus Is Maintained by Inflammatory Recruitment of Susceptible Myeloid Cells
    1
    1. scibot 09 Aug 2021
      RRID:AB_1107769

      DOI: 10.1016/j.chom.2018.10.003

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    sciencedirect.com/science/article/pii/S1931312818305419
  21. www.sciencedirect.com www.sciencedirect.com
    Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection
    1
    1. scibot 07 Aug 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cell.2018.04.006

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    sciencedirect.com/science/article/pii/S0092867418304598
  22. www.sciencedirect.com www.sciencedirect.com
    Exploring the longitudinal glioma microenvironment landscape uncovers reprogrammed pro-tumorigenic neutrophils in the bone marrow
    1
    1. scibot 04 Aug 2021
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2021.109480

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    sciencedirect.com/science/article/pii/S2211124721009074
  23. www.sciencedirect.com www.sciencedirect.com
    Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
    1
    1. scibot 01 Aug 2021
      AB_1107769

      DOI: 10.1016/j.immuni.2018.11.014

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    sciencedirect.com/science/article/pii/S1074761318305223
  24. Jul 2021
  25. www.sciencedirect.com www.sciencedirect.com
    Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury
    1
    1. scibot 31 Jul 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cell.2018.12.022

      Resource: (Bio X Cell Cat# BE0089, RRID:AB_1107769)

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S0092867418316362
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 30 Jul 2021
      RRID:AB_1107769

      DOI: 10.1016/j.immuni.2018.10.007

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    ncbi.nlm.nih.gov/pmc/articles/PMC6303219/
  27. www.sciencedirect.com www.sciencedirect.com
    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
    1
    1. scibot 30 Jul 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cell.2018.10.038

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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867418313941
  28. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 28 Jul 2021
      RRID:AB_1107769

      DOI: 10.1016/j.immuni.2018.09.024

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    sciencedirect.com/science/article/pii/S1074761318304394
  29. www.sciencedirect.com www.sciencedirect.com
    Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation
    1
    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.chom.2017.06.006

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      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1931312817302469
  30. www.sciencedirect.com www.sciencedirect.com
    Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity
    2
    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.cell.2017.05.005

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    2. scibot 28 Jul 2021
      AB_1107769

      DOI: 10.1016/j.cell.2017.05.005

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    sciencedirect.com/science/article/pii/S0092867417305329
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma
    1
    1. scibot 21 Jul 2021
      RRID:AB_1107769

      DOI: 10.1016/j.isci.2021.102759

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    ncbi.nlm.nih.gov/pmc/articles/PMC8267546/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipopolysaccharide-mediated chronic inflammation promotes tobacco carcinogen-induced lung cancer and determines the efficacy of immunotherapy
    1
    1. scibot 03 Jul 2021
      RRID:AB_1107769

      DOI: 10.1158/0008-5472.CAN-20-1994

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    ncbi.nlm.nih.gov/pmc/articles/PMC7878420/
  33. Jun 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
    1
    1. scibot 23 Jun 2021
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2021.109285

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    sciencedirect.com/science/article/pii/S2211124721006562
  35. www.sciencedirect.com www.sciencedirect.com
    A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression
    1
    1. scibot 19 Jun 2021
      RRID:_AB_1107769

      DOI: 10.1016/j.immuni.2021.05.016

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    sciencedirect.com/science/article/pii/S1074761321002223
  36. www.sciencedirect.com www.sciencedirect.com
    Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response
    1
    1. scibot 15 Jun 2021
      RRID:AB_1107769

      DOI: 10.1016/j.xpro.2021.100595

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    sciencedirect.com/science/article/pii/S2666166721003026
  37. www.sciencedirect.com www.sciencedirect.com
    GPR34-mediated sensing of lysophosphatidylserine released by apoptotic neutrophils activates type 3 innate lymphoid cells to mediate tissue repair
    1
    1. scibot 09 Jun 2021
      RRID:AB_1107769

      DOI: 10.1016/j.immuni.2021.05.007

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    sciencedirect.com/science/article/pii/S1074761321002132
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection
    1
    1. scibot 04 Jun 2021
      RRID:AB_1107769

      DOI: 10.7554/eLife.65762

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    ncbi.nlm.nih.gov/pmc/articles/PMC8163503/
  39. www.sciencedirect.com www.sciencedirect.com
    Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity
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    1. scibot 03 Jun 2021
      RRID:AB_1107769

      DOI: 10.1016/j.cell.2021.05.021

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    sciencedirect.com/science/article/pii/S0092867421006516
  40. May 2021
  41. www.sciencedirect.com www.sciencedirect.com
    The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
    1
    1. scibot 12 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.immuni.2021.04.019

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    sciencedirect.com/science/article/pii/S1074761321001813
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    A vaccine inducing solely cytotoxic T lymphocytes fully prevents Zika virus infection and fetal damage
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    1. scibot 12 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2021.109107

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    sciencedirect.com/science/article/pii/S2211124721004411
  43. www.sciencedirect.com www.sciencedirect.com
    BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse
    1
    1. scibot 09 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.stem.2020.06.022

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    sciencedirect.com/science/article/pii/S1934590920302897
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    Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress
    1
    1. scibot 08 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.molcel.2021.02.038

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    sciencedirect.com/science/article/pii/S1097276521001684
  45. www.sciencedirect.com www.sciencedirect.com
    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
    1
    1. scibot 08 May 2021
      RRID:AB_1107769

      DOI: 10.1016/j.molcel.2021.01.010

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    sciencedirect.com/science/article/pii/S1097276521000101
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    Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.immuni.2020.12.004

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  47. www.sciencedirect.com www.sciencedirect.com
    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
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  49. www.sciencedirect.com www.sciencedirect.com
    Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation
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  50. Apr 2021
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    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
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    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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    CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
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    Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis
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    The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis
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    Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance
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    The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes
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    Interaction between Staphylococcus Agr virulence and neutrophils regulates pathogen expansion in the skin
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    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
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      InVivoPlus rat IgG2a isotype control

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    Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP
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  61. Mar 2021
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    Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor
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  64. www.sciencedirect.com www.sciencedirect.com
    Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
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  65. Feb 2021
  66. www.jimmunol.org www.jimmunol.org
    Transcriptional Diversity and Niche-Specific Distribution of Leukocyte Populations during Staphylococcus aureus Craniotomy-Associated Biofilm Infection
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      DOI: 10.4049/jimmunol.2001042

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  67. insight.jci.org insight.jci.org
    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
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      DOI: 10.1172/jci.insight.134386

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  68. elifesciences.org elifesciences.org
    IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus
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      DOI: 10.7554/eLife.45501

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  69. www.cell.com www.cell.com
    Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation
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  70. Dec 2020
  71. www.sciencedirect.com www.sciencedirect.com
    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
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  72. Oct 2020
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    PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury
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  75. Sep 2020
  76. www.sciencedirect.com www.sciencedirect.com
    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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    Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
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    TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes
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    FOXD3 Regulates VISTA Expression in Melanoma
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  80. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis
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    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
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    Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy
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  83. insight.jci.org insight.jci.org
    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
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    An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses
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    Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells
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      DOI: 10.1016/j.cell.2020.04.022

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    Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity
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    Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps
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    The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
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  89. www.sciencedirect.com www.sciencedirect.com
    Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection
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      Isotype (rat IgG2a isotype)

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  90. Jan 2020
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors
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      DOI: 10.1016/j.cell.2019.05.047

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    T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation
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    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
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    B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer
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    Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
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    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
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    Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis
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    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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    Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
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    Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization
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    CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota
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    IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties
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    Staphylococcus aureus Leukocidins Target Endothelial DARC to Cause Lethality in Mice
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    Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis
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    Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury
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    Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
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  112. Nov 2018
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    CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis
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    Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis
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    IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy
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    LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade
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    Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy
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    Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity
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    RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis
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    Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
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    B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells
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    Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization
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    TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer
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    Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation
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    Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer
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  128. Nov 2017
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    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
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    Dietary Manganese Promotes Staphylococcal Infection of the Heart
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    Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever
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    Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
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