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  1. Nov 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
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      DOI: 10.1016/j.immuni.2023.10.004

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    sciencedirect.com/science/article/pii/S1074761323004442
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    Exploring the role of SWI/SNF complex subunit BAF60c in lipid metabolism and inflammation in fish
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      DOI: 10.1016/j.isci.2023.108207

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    sciencedirect.com/science/article/pii/S2589004223022848
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    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
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      DOI: 10.1126/science.adh5021

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    ncbi.nlm.nih.gov/pmc/articles/PMC10617673/
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    Targeted Nanofitin-drug Conjugates Achieve Efficient Tumor Delivery and Therapeutic Effect in an EGFRpos Mouse Xenograft Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC10618730/
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    The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing
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    sciencedirect.com/science/article/pii/S2211124723013591
  7. Oct 2023
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    JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
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    sciencedirect.com/science/article/pii/S221112472301135X
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    A neural pathway underlying hunger modulation of sexual receptivity in Drosophila females
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    sciencedirect.com/science/article/pii/S221112472301255X
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    Modification of Lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression
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    1. scibot 21 Oct 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10585400/
  11. 52.53.155.43 52.53.155.43
    Blocking oligomerization is the most viable strategy to inhibit STING
    1
    1. scibot 20 Oct 2023
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  12. www.embopress.org www.embopress.org
    The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes
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    1. scibot 20 Oct 2023
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      DOI: 10.15252/embr.202356815

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    embopress.org/doi/10.15252/embr.202356815
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zmym4 is required for early cranial gene expression and craniofacial cartilage formation
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      DOI: 10.3389/fcell.2023.1274788

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    ncbi.nlm.nih.gov/pmc/articles/PMC10579616/
  14. www.science.org www.science.org
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
    1
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    Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness
    1
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    sciencedirect.com/science/article/pii/S2211124723012585
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Syndapin and GTPase RAP-1 control endocytic recycling via RHO-1 and non-muscle myosin II
    1
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      DOI: 10.1016/j.cub.2023.09.051

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    pmc.ncbi.nlm.nih.gov/articles/PMC10841897/
  17. 52.53.155.43 52.53.155.43
    Organization of an Ascending Circuit that Conveys Flight Motor State
    1
    1. scibot 13 Oct 2023
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    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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    sciencedirect.com/science/article/pii/S1097276523007025
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    TRIM11 attenuates Treg cell differentiation by p62-selective autophagic degradation of AIM2
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      DOI: 10.1016/j.celrep.2023.113231

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    sciencedirect.com/science/article/pii/S2211124723012433
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequence-directed concentration of G protein-coupled receptors in COPII vesicles
    1
    1. scibot 07 Oct 2023
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      DOI: 10.1016/j.isci.2023.107969

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    ncbi.nlm.nih.gov/pmc/articles/PMC10551652/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells
    1
    1. scibot 06 Oct 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10528745/
  22. www.cell.com www.cell.com
    AMER1 deficiency promotes the distant metastasis of colorectal cancer by inhibiting SLC7A11- and FTL-mediated ferroptosis
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    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113110

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    cell.com/cell-reports/abstract/S2211-1247(23)01121-X
  23. www.cell.com www.cell.com
    The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
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    cell.com/cell-reports/abstract/S2211-1247(23)01092-6
  24. www.cell.com www.cell.com
    MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis
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    cell.com/cell-reports/abstract/S2211-1247(23)01034-3
  25. 52.53.155.43 52.53.155.43
    PIIS0092867423009650-html.html
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  26. Sep 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Hyperpolarization-activated cyclic nucleotide-gated cation channel 3 promotes HCC development in a female-biased manner
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    sciencedirect.com/science/article/pii/S2211124723011695
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    Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
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      DOI: 10.1016/j.chom.2023.08.003

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    sciencedirect.com/science/article/pii/S1931312823003281
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    NSD2 methylates AROS to promote SIRT1 activation and regulates fatty acid metabolism-mediated cancer radiotherapy
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    Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis
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    Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells
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    sciencedirect.com/science/article/pii/S1097276523006950
  32. www.biorxiv.org www.biorxiv.org
    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
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      DOI: 10.1101/2023.09.25.559255

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    biorxiv.org/content/10.1101/2023.09.25.559255v1
  33. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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    nature.com/articles/s41422-023-00874-4
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    Identification of genes required for Plasmodium gametocyte-to-sporozoite development in the mosquito vector
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  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E2 enzyme Bruce negatively regulates Hippo signaling through POSH-mediated expanded degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10497580/
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    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10475482/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterogeneous receptor expression underlies non-uniform peptidergic modulation of olfaction in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC10465596/
  39. Aug 2023
  40. www.science.org www.science.org
    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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      DOI: 10.1126/science.adi3448

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    science.org/doi/10.1126/science.adi3448
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    GSK3 and lamellipodin balance lamellipodial protrusions and focal adhesion maturation in mouse neural crest migration
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    sciencedirect.com/science/article/pii/S2211124723010410
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability
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    ncbi.nlm.nih.gov/pmc/articles/PMC10432822/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10424150/
  44. 52.53.155.43 52.53.155.43
    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
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    NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer
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    A novel immune modulator IM33 mediates a glia-gut-neuronal axis that controls lifespan
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    Homeostatic Regulation of Seizure Susceptibility and Cognitive Function by ER Quality Controller Derlin-1 through Maintenance of Adult Neurogenesis
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    A unique role for Protocadherin γC3 in promoting dendrite arborization through an Axin1-dependent mechanism
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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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    Coronavirus Subverts ER-phagy by Hijacking FAM134B and ATL3 into p62 Condensates to Facilitate Viral Replication
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    Axon targeting of Drosophila medulla projection neurons requires diffusible Netrin and is coordinated with neuroblast temporal patterning
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    Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation
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    Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells
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    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
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    Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks
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    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
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    Intron retention of an adhesion GPCR generates single transmembrane-helix isoforms to enable 7TM-adhesion GPCR function
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    SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
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    Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
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    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
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    The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2
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