591 Matching Annotations
  1. Jan 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Immunoediting instructs tumor metabolic reprogramming to support immune evasion
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    1. scibot 04 Jan 2023
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  3. Dec 2022
  4. www.mdpi.com www.mdpi.com
    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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  5. www.jci.org www.jci.org
    Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation
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    1. scibot 06 Dec 2022
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      DOI: 10.1172/JCI158096

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    jci.org/articles/view/158096
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hedgehog regulation of epithelial cell state and morphogenesis in the larynx
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    1. scibot 06 Dec 2022
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      DOI: 10.7554/eLife.77055

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    ncbi.nlm.nih.gov/pmc/articles/PMC9718526/
  7. aacrjournals.org aacrjournals.org
    Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma
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    1. scibot 04 Dec 2022
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      DOI: 10.1158/1541-7786.MCR-22-0040

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    aacrjournals.org/mcr/article/20/12/1811/711004/Raptinal-Induces-Gasdermin-E-Dependent-Pyroptosis
  8. Nov 2022
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    Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling
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  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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    Cancer cells co-opt nociceptive nerves to thrive in nutrient-poor environments and upon nutrient-starvation therapies
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    Ptp61F integrates Hippo, TOR, and actomyosin pathways to control three-dimensional organ size
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    sciencedirect.com/science/article/pii/S221112472201511X
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    Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma
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    Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma
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    sciencedirect.com/science/article/pii/S2211124722014668
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    The Rb/E2F axis is a key regulator of the molecular signatures instructing the quiescent and activated adult neural stem cell state
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    sciencedirect.com/science/article/pii/S2211124722014395
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    Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
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    1. scibot 03 Nov 2022
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  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Photothermal effects of CuS-BSA nanoparticles on H22 hepatoma-bearing mice
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    1. scibot 02 Nov 2022
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      DOI: 10.3389/fphar.2022.1029986

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  18. www.science.org www.science.org
    Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis
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    1. scibot 01 Nov 2022
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      DOI: 10.1126/sciimmunol.abm9811

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  19. Oct 2022
  20. 52.53.155.43 52.53.155.43
    mcr-22-0040-html.html
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  21. academic.oup.com academic.oup.com
    Follicle stimulating hormone glycosylation variants distinctly modulate pre-antral follicle growth and survival
    1
    1. scibot 28 Oct 2022
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      DOI: 10.1210/endocr/bqac161

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    academic.oup.com/endo/article/163/12/bqac161/6750033
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schwann cells-derived exosomal miR-21 participates in high glucose regulation of neurite outgrowth
    1
    1. scibot 08 Oct 2022
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      DOI: 10.1016/j.isci.2022.105141

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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma
    1
    1. scibot 02 Oct 2022
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      DOI: 10.1016/j.isci.2022.105118

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    ncbi.nlm.nih.gov/pmc/articles/PMC9519628/
  24. Sep 2022
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease
    1
    1. scibot 30 Sep 2022
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      DOI: 10.1016/j.isci.2022.105145

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    ncbi.nlm.nih.gov/pmc/articles/PMC9513272/
  26. www.sciencedirect.com www.sciencedirect.com
    Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
    1
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    sciencedirect.com/science/article/pii/S1535610822003786
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    CDK14 inhibition reduces mammary stem cell activity and suppresses triple negative breast cancer progression
    1
    1. scibot 15 Sep 2022
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    sciencedirect.com/science/article/pii/S2211124722011597
  28. journals.plos.org journals.plos.org
    CCT196969 effectively inhibits growth and survival of melanoma brain metastasis cells
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      DOI: 10.1371/journal.pone.0273711

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  29. www.jneurosci.org www.jneurosci.org
    c-Kit Receptor Maintains Sensory Axon Innervation of the Skin through Src Family Kinases
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      DOI: 10.1523/JNEUROSCI.0618-22.2022

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    jneurosci.org/content/42/36/6835
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
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      DOI: 10.1158/2159-8290.CD-21-0694

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904293/
  31. Aug 2022
  32. journals.lww.com journals.lww.com
    Chronic spinal cord compression associated with... : Neural Regeneration Research
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      DOI: 10.4103/1673-5374.350210

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    journals.lww.com/nrronline/Fulltext/2023/03000/Chronic_spinal_cord_compression_associated_with.42.aspx
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC9396479/
  34. www.sciencedirect.com www.sciencedirect.com
    Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster
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    Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition
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    Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease
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    Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids
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  38. aacrjournals.org aacrjournals.org
    Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification
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      DOI: 10.1158/0008-5472.CAN-22-0225

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    aacrjournals.org/cancerres/article/82/14/2576/706950/Proteomic-Mapping-and-Targeting-of-Mitotic
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    Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE
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    Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
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    Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury
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    N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis
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  43. Jul 2022
  44. www.sciencedirect.com www.sciencedirect.com
    High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition
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  45. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html
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    FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma
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    Guiding ATR and PARP inhibitor combinationswith chemogenomic screens
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  91. Jan 2022
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    The cross-talk between Bax, Bcl2, caspases, and DNA damage in bystander HepG2 cells is regulated by γ-radiation dose and time of conditioned media transfer
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    Disrupted Association of Sensory Neurons With Enveloping Satellite Glial Cells in Fragile X Mouse Model
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    Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes
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    An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion
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    Bortezomib Alone and in Combination With Salinosporamid A Induces Apoptosis and Promotes Pheochromocytoma Cell Death In Vitro and in Female Nude Mice
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    NHERF1 Is Required for Localization of PMCA2 and Suppression of Early Involution in the Female Lactating Mammary Gland
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    Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation
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    GX15–070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma
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      Cleaved Caspase-3

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    Fluoxetine and its metabolite norfluoxetine induce microglial apoptosis
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    mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
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      Cleaved Caspase-3 D175

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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  172. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    The NF-κB Factor Relish Regulates Atg1 Expression and Controls Autophagy
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  177. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  178. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Japanese Encephalitis Virus‐induced let‐7a/b interacted with the NOTCH‐TLR7 pathway in microglia and facilitated neuronal death via caspase activation
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZPK/DLK and MKK4 Form the Critical Gateway to Axotomy-Induced Motoneuron Death in Neonates
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      RRID:AB_331453

      DOI: 10.1523/JNEUROSCI.0539-14.2014

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    ncbi.nlm.nih.gov/pmc/articles/PMC4200111/
  180. www.nature.com www.nature.com
    Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC
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      9664s

      DOI: 10.1038/s41388-021-01869-4

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    nature.com/articles/s41388-021-01869-4
  181. www.sciencedirect.com www.sciencedirect.com
    A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope
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      RRID:AB_2070042

      DOI: 10.1016/j.xcrm.2021.100344

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    sciencedirect.com/science/article/pii/S2666379121001932
  182. www.sciencedirect.com www.sciencedirect.com
    An iPSC model of hereditary sensory neuropathy-1 reveals L-serine-responsive deficits in neuronal ganglioside composition and axoglial interactions
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      RRID:AB_2070042

      DOI: 10.1016/j.xcrm.2021.100345

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    sciencedirect.com/science/article/pii/S2666379121001944
  183. www.sciencedirect.com www.sciencedirect.com
    Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm
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      9664

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    sciencedirect.com/science/article/pii/S0002929721002408
  184. www.sciencedirect.com www.sciencedirect.com
    Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication
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  185. www.sciencedirect.com www.sciencedirect.com
    Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis
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      RRID:AB_2070042

      DOI: 10.1016/j.celrep.2021.109315

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  186. www.cell.com www.cell.com
    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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  187. www.sciencedirect.com www.sciencedirect.com
    Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
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      RRID:AB_2070042

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    sciencedirect.com/science/article/pii/S153458072100486X
  188. Jun 2021
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    High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity
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    sciencedirect.com/science/article/pii/S2211124721005623
  190. May 2021
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    SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
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      DOI: 10.1016/j.molcel.2021.04.002

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  192. www.sciencedirect.com www.sciencedirect.com
    DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance
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  193. www.sciencedirect.com www.sciencedirect.com
    Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury
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    Plasmalogen attenuates the development of hepatic steatosis and cognitive deficit through mechanism involving p75NTR inhibition
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      DOI: 10.1016/j.redox.2021.102002

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    Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis
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      DOI: 10.1016/j.stem.2020.04.018

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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program
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    Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression
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    Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer
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    DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation
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      RRID:AB_2070042

      DOI: 10.1016/j.devcel.2020.09.021

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    DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma
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      RRID:AB_2070042

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    sciencedirect.com/science/article/pii/S1534580720304160
  201. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Elevated GFAP isoform expression promotes protein aggregation and compromises astrocyte function
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      AB_2070042

      DOI: 10.1096/fj.202100087R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100087R
  202. www.sciencedirect.com www.sciencedirect.com
    Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer
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      RRID:AB_2070042

      DOI: 10.1016/j.cmet.2021.01.018

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    sciencedirect.com/science/article/pii/S1550413121000565
  203. Apr 2021
  204. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer
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      RRID:AB_2070042

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    sciencedirect.com/science/article/pii/S1550413120305519
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    Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
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      RRID:AB_2070042

      DOI: 10.1016/j.cell.2020.10.016

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    sciencedirect.com/science/article/pii/S0092867420313222
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    Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells
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      RRID:AB_2070042

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    Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense
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      RRID:AB_2070042

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    sciencedirect.com/science/article/pii/S2211124721003260
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    PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression
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    sciencedirect.com/science/article/pii/S1535610820302683
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    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
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    sciencedirect.com/science/article/pii/S1535610820302130
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    Mitochondrial biogenesis in developing astrocytes regulates astrocyte maturation and synapse formation
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    sciencedirect.com/science/article/pii/S2211124721002667
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    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG
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    sciencedirect.com/science/article/pii/S2211124721003089
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    PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis
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    The multitargeted kinase inhibitor KW-2449 ameliorates cisplatin-induced nephrotoxicity by targeting RIPK1-mediated necroptosis
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      anti-cleaved caspase 3

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    sciencedirect.com/science/article/pii/S0006295221001386
  214. Mar 2021
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    Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice
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    Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination
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    Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition
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  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isorhamnetin Inhibits Human Gallbladder Cancer Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway Inactivation
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      DOI: 10.3389/fphar.2021.628621

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  219. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence
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      DOI: 10.1096/fj.202001855RR

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