679 Matching Annotations
  1. Dec 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10679816/
  3. Nov 2023
  4. www.sciencedirect.com www.sciencedirect.com
    Airway epithelial cells and macrophages trigger IL-6-CD95/CD95L axis and mediate initial immunopathology of COVID-19
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    sciencedirect.com/science/article/pii/S2589004223024434
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    Evolutionary diversification reveals distinct somatic versus germline cytoskeletal functions of the Arp2 branched actin nucleator protein
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    sciencedirect.com/science/article/pii/S0960982223014562
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    Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities
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    sciencedirect.com/science/article/pii/S2211124723015085
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    HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B
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    sciencedirect.com/science/article/pii/S2666379123004792
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    p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
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    sciencedirect.com/science/article/pii/S2211124723006708
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    Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidation
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    sciencedirect.com/science/article/pii/S2211124723013736
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    MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice
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    link.springer.com/article/10.1186/s40478-023-01654-2
  11. Oct 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The microbial metabolite desaminotyrosine enhances T-cell priming and cancer immunotherapy with immune checkpoint inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10597767/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
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    ncbi.nlm.nih.gov/pmc/articles/PMC10570680/
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    Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease
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    sciencedirect.com/science/article/pii/S2666379123004135
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    Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain
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    cell.com/iscience/abstract/S2589-0042(23)02087-4
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    Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00350-X/fulltext
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    BPS Publications
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    52.53.155.43/6079453bbbf12bd08872d5439d37d8b14bece994/British J Pharmacology - 2023 - Chen - DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A2-html.html
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    FSHR-mTOR-HIF1 signaling alleviates mouse follicles from AMPK-induced atresia
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    sciencedirect.com/science/article/pii/S2211124723011701
  20. Sep 2023
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    20-αHydroxycholesterol, an oxysterol in human breast milk, reverses mouse neonatal white matter injury through Gli-dependent oligodendrogenesis
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    sciencedirect.com/science/article/pii/S1934590923002552
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    SMAD4 and KCNQ3 alterations are associated with lymph node metastases in Oesophageal adenocarcinoma
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    sciencedirect.com/science/article/pii/S0925443923002338
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  24. dx.doi.org dx.doi.org
    TRβ Agonism Induces Tumor Suppression and Enhances Drug Efficacy in Anaplastic Thyroid Cancer in Female Mice
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    dx.doi.org/10.1210/endocr/bqad135
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    Histone bivalency regulates the timing of cerebellar granule cell development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10499015/
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    LSR targets YAP to modulate intestinal Paneth cell differentiation
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    sciencedirect.com/science/article/pii/S2211124723011300
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC10481131/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor
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    ncbi.nlm.nih.gov/pmc/articles/PMC10473160/
  29. Aug 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Lipocalin-2 induces mitochondrial dysfunction in renal tubular cells via mTOR pathway activation
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    sciencedirect.com/science/article/pii/S2211124723010434
  31. 52.53.155.43 52.53.155.43
    A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis
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    γ-radiation-induced damage on normal hepatocytes and its protection by ethyl cinnamate
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    link.springer.com/article/10.1007/s10967-023-09067-0
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10412558/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10409725/
  35. 52.53.155.43 52.53.155.43
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    Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms
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    sciencedirect.com/science/article/pii/S2352396423003171
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10393801/
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    sciencedirect.com/science/article/pii/S2211124723009385
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    52.53.155.43/d8c850c315bd1ef9a1794152cac296a4123affe5/British J Pharmacology - 2023 - Wang - Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3-html.html
  40. Jul 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
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    sciencedirect.com/science/article/pii/S1535610823002179
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    Improvement of sensory deficits in fragile X mice by increasing cortical interneuron activity after the critical period
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    sciencedirect.com/science/article/pii/S0896627323004683
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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10320471/
  45. dx.doi.org dx.doi.org
    Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model via induction of Apoptosis
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    dx.doi.org/10.1158/1535-7163.MCT-22-0224
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9812929/
  47. 52.53.155.43 52.53.155.43
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  48. Jun 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Fancm has dual roles in the limiting of meiotic crossovers and germ cell maintenance in mammals
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    sciencedirect.com/science/article/pii/S2666979X23001246
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285642/
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    Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons
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    sciencedirect.com/science/article/pii/S1534580723002459
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10267679/
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    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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    sciencedirect.com/science/article/pii/S2211124723006277
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    SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury
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    sciencedirect.com/science/article/pii/S2589004223010301
  55. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  56. 52.53.155.43 52.53.155.43
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  57. 52.53.155.43 52.53.155.43
    RORψt+CD4+ T cells promote IL-23R-mediated neuronal cell apoptosis in the central nervous system
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    52.53.155.43/333ed306ab43198840b04e278f040205d2c57b40/2023.04.17.537133v1.full-html.html
  58. May 2023
  59. www.embopress.org www.embopress.org
    Phospholipid scramblase Xkr8 is required for developmental axon pruning via phosphatidylserine exposure
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    embopress.org/doi/10.15252/embj.2022111790
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    VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection
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    Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin
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  63. www.sciencedirect.com www.sciencedirect.com
    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma
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    sciencedirect.com/science/article/pii/S2451945622002422
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Diversity within olfactory sensory derivatives revealed by the contribution of Dbx1 lineages
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    onlinelibrary.wiley.com/doi/10.1002/cne.25492
  66. Apr 2023
  67. www.sciencedirect.com www.sciencedirect.com
    Alphavirus infection triggers antiviral RNAi immunity in mammals
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    Semi-Supervised Analysis of myeloid and T cell behaviour in ex vivo ovarian tumour slices reveals changes in cell motility after treatments
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    Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons
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    sciencedirect.com/science/article/pii/S2211124723004096
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    Beclin-1-dependent autophagy, but not apoptosis, is critical for stem-cell-mediated endometrial programming and the establishment of pregnancy
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    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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    sciencedirect.com/science/article/pii/S2666379123001179
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor microenvironment mimicking 3D models unveil the multifaceted effects of SMAC mimetics
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    ncbi.nlm.nih.gov/pmc/articles/PMC10064235/
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    Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen
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    sciencedirect.com/science/article/pii/S0092867423002118
  74. Mar 2023
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10036134/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10027750/
  77. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout
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    pubmed.ncbi.nlm.nih.gov/36930645/
  78. 52.53.155.43 52.53.155.43
    Generation and expansion of transitional lung organoids from human pluripotent stem cells
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    52.53.155.43/ba62128acd6e3f7c070d6d9a373799060570fdfd/2023.01.30.526265v1.full-html.html
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    Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2
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    sciencedirect.com/science/article/pii/S1534580723000461
  80. Feb 2023
  81. www.sciencedirect.com www.sciencedirect.com
    Injury primes mutation-bearing astrocytes for dedifferentiation in later life
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    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC9912829/
  84. aacrjournals.org aacrjournals.org
    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stress Granules determine the Development of Obesity-associated Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357213/
  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    AMP-activated protein kinase inhibition in fibro-adipogenic progenitors impairs muscle regeneration and increases fibrosis
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    onlinelibrary.wiley.com/doi/10.1002/jcsm.13150
  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endoplasmic reticulum associated degradation is essential for maintaining the viability or function of mature myelinating cells in adults
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    onlinelibrary.wiley.com/doi/10.1002/glia.24346
  88. Jan 2023
  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In vitro characterization on the role of APOE polymorphism in human hippocampal neurogenesis
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    onlinelibrary.wiley.com/doi/10.1002/hipo.23502
  90. www.sciencedirect.com www.sciencedirect.com
    Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex
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    sciencedirect.com/science/article/pii/S2211124722018769
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9834662/
  92. 52.53.155.43 52.53.155.43
    Global cancer statistics, 2012
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel B7-H6–Targeted IgG-Like T Cell–Engaging Antibody for the Treatment of Gastrointestinal Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9713360/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437563/
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    Immunoediting instructs tumor metabolic reprogramming to support immune evasion
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