1,231 Matching Annotations
  1. Jun 2025
  2. www.sciencedirect.com www.sciencedirect.com
    MT-125 inhibits non-muscle myosin IIA and IIB and prolongs survival in glioblastoma
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    sciencedirect.com/science/article/pii/S0092867425005690
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nerve growth factor signaling tunes axon maintenance protein abundance and kinetics of Wallerian degeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12005098/
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    PIN1 serves as a prognostic and therapeutic biomarker in lung adenocarcinoma
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    link.springer.com/article/10.1007/s10142-025-01629-7
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    A triple serine motif in the intracellular domain of SorCS2 impacts its cellular signaling
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    sciencedirect.com/science/article/pii/S2589004225009563
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    Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy
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    sciencedirect.com/science/article/pii/S1074761325002274
  7. May 2025
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    Bromodomain-containing protein 4 knockdown promotes... : Neural Regeneration Research
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    journals.lww.com/nrronline/fulltext/2026/02000/bromodomain_containing_protein_4_knockdown.41.aspx
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Surrogate GPR139 Agonists Reverse Short‐Term Startle Habituation Impairment in Larval Zebrafish
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    pmc.ncbi.nlm.nih.gov/articles/PMC12097293/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Focal Adhesion Kinase Orchestrates GLUT4 Translocation and Glucose Uptake via Cytoskeletal Turnover in Primary Adipocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12093284/
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    Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis
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    sciencedirect.com/science/article/pii/S0092867425005021
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12055001/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical Activity of the Type II RAF Inhibitor Tovorafenib in Tumor Models Harboring Either a BRAF Fusion or an NF1 Loss-of-Function Mutation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12015663/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
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    TNF‐α‐Driven Changes in Polarized EGF Receptor Trafficking Facilitate Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling From the Apical Surface of MDCK Epithelial Cells
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    Phenotypic heterogeneity and plasticity in colorectal cancer metastasis
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    sciencedirect.com/science/article/pii/S2666979X25001375
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    The biased OTR ligands -atosiban and carbetocin- differentially inhibit early or late formalin-induced nociception in rats
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    Independent and synergistic roles of MEK-ERK1/2 and PKC pathways in regulating functional changes in vascular tissue following flow cessation
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    A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons
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    Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of LSD1 and OXPHOS
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    KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy
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  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Growth Hormone Promotes Lipolysis and Impairs Insulin Sensitivity by Activating the ERK/HSL Signaling Pathway in Bovine Adipocytes
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    onlinelibrary.wiley.com/doi/10.1002/aro2.70015
  23. Apr 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interleukin-33 (IL-33) promotes DNA damage-resistance in lung cancer
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    CAN-Scan: A multi-omic phenotype-driven precision oncology platform identifies prognostic biomarkers of therapy response for colorectal cancer
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    Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies
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    Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways
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  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Xuebijing injection alleviates septic acute kidney injury by modulating inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress
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    Scutellaria barbata ameliorates acute respiratory distress syndrome by inhibiting neutrophil-mediated inflammatory responses
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  31. Mar 2025
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    Geometric deep learning and multiple-instance learning for 3D cell-shape profiling
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    A microglia clonal inflammatory disorder in Alzheimer’s disease
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    Macrophage-specific PHGDH protects against MAFLD by suppressing TAK1
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    Monocytes from patients with myelodysplastic syndrome inhibit natural killer cell-mediated antitumor function through the CD200/CD200R pathway
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    ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity
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    Large-scale control over collective cell migration using light-activated epidermal growth factor receptors
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  39. Feb 2025
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    MIF-ACKR3 causes irreversible fat loss by impairing adipogenesis in cancer cachexia
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    FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma
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  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis
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  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Taming interleukin-12: Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities
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    onlinelibrary.wiley.com/doi/10.1002/pro.70072
  45. journals.biologists.com journals.biologists.com
    Akt is a mediator of artery specification during zebrafish development
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    journals.biologists.com/dev/article/151/17/dev202727/361847/Akt-is-a-mediator-of-artery-specification-during
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    The TSH receptor antibody reactome contributes to retro-orbital inflammation
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    dx.doi.org/10.1210/jendso/bvae182
  47. dx.doi.org dx.doi.org
    Relaxin Modulates the Genomic Actions and Biological Effects of Estrogen in the Myometrium
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  48. link.springer.com link.springer.com
    Identification of Meibomian gland stem cell populations and mechanisms of aging
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    link.springer.com/article/10.1038/s41467-025-56907-6
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    Sustained NF-κB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor initiation
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  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling
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    KRAS4B oncogenic mutants promote non-small cell lung cancer progression via the interaction of deubiquitinase USP25 with RNF31
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  53. aacrjournals.org aacrjournals.org
    TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma
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    aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined inhibition of focal adhesion kinase and RAF/MEK elicits synergistic inhibition of melanoma growth and reduces metastases
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    pmc.ncbi.nlm.nih.gov/articles/PMC11866499/
  56. 52.53.155.43 52.53.155.43
    The propensity of fructose to induce metabolic dysfunction is dependent on the baseline diet, length of the dietary exposure, and sex of the mice
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    Disrupting AGR2/IGF1 paracrine and reciprocal signaling for pancreatic cancer therapy
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    Oligodendrocytes drive neuroinflammation and neurodegeneration in Parkinson’s disease via the prosaposin-GPR37-IL-6 axis
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  59. Jan 2025
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    Neoadjuvant immunotherapy with or without chemotherapy in locally advanced oral squamous cell carcinoma: Randomized, two-arm, phase 2 trial
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  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis
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    OXCT1 succinylation and activation by SUCLA2 promotes ketolysis and liver tumor growth
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    A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance
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  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial and Single-Cell Analyses Reveal Heterogeneity of DNAM-1 Receptor–Ligand Interactions That Instructs Intratumoral γδT-cell Activity
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    A pair of LysM receptors mediates symbiosis and immunity discrimination in Marchantia
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    Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells
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    CDK2 activity crosstalk on the ERK kinase translocation reporter can be resolved computationally
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    Nuclear adenine activates hnRNPA2B1 to enhance antibacterial innate immunity
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    5’-cap-dependent translation as a potent therapeutic target for lethal human squamous cell carcinoma
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    Orthogonal RNA replication enables directed evolution and Darwinian adaptation in mammalian cells
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    Ketamine and Major Ketamine Metabolites Function as Allosteric Modulators of Opioid Receptors
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    Histone acetylation alteration by KAT6A inhibitor WM-1119 suppresses IgE-mediated mast cell activation and allergic inflammation via reduction in AP-1 signaling
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    Calcineurin: An essential regulator of sleep revealed by biochemical, chemical biological, and genetic approaches
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  76. Dec 2024
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    The Impact of a Ketogenic Diet on Late-Stage Pancreatic Carcinogenesis in Mice: Efficacy and Safety Studies
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    TRPA1 contributes to respiratory depression from tobacco aerosol
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    Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
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    MAPK pathways regulated apoptosis and pyroptosis in respiratory epithelial cells of a primitive vertebrate model during bacterial infection
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    GABAA receptor π forms channels that stimulate ERK through a G-protein-dependent pathway
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    Antagonistic systemin receptors integrate the activation and attenuation of systemic wound signaling in tomato
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    Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discovery
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  86. Nov 2024
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Calcium-dependent regulation of neuronal excitability is rescued in Fragile X Syndrome by a tat-conjugated N-terminal fragment of FMRP
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    HucMSCs can alleviate abnormal vasculogenesis induced by high glucose through the MAPK signaling pathway
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    ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion
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  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microglia-derived ADAM9 promote GHRH neurons pyroptosis by Mad2L2-JNK-caspase-1 pathway in subarachnoid hemorrhage
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    Bilateral regulation of EGFR activity and local PI(4,5)P2 dynamics in mammalian cells observed with superresolution microscopy
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  186. Apr 2024
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