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Feb 2024
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Structural changes in cell wall pectic polymers contribute to freezing tolerance induced by cold acclimation in plants

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  DOI: 10.1016/j.cub.2024.01.045
  
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Neurogenesis-mediated circuit remodeling reduces engram reinstatement and promotes forgetting

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1. scibot 04 Feb 2024
  
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  DOI: 10.1101/2023.10.10.561722
  
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biorxiv.org/content/10.1101/2023.10.10.561722v1
Jan 2024
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Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.celrep.2023.113613
  
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Cytoneme signaling provides essential contributions to mammalian tissue patterning

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1. scibot 07 Jan 2024
  
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  DOI: 10.1016/j.cell.2023.12.003
  
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sciencedirect.com/science/article/pii/S0092867423013338
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Therapy-induced normal tissue damage promotes breast cancer metastasis

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1. scibot 05 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108503
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10755366/
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Gbb glutathionylation promotes its proteasome-mediated degradation to inhibit synapse growth

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1. scibot 05 Jan 2024
  
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  DOI: 10.1083/jcb.202202068
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10316630/
Dec 2023
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Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells

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1. scibot 21 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108564
  
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sciencedirect.com/science/article/pii/S258900422302641X
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Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation

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1. scibot 19 Dec 2023
  
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  DOI: 10.1016/j.cmet.2023.11.012
  
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sciencedirect.com/science/article/pii/S1550413123004448
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Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling

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1. scibot 19 Dec 2023
  
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  DOI: 10.1016/j.devcel.2023.11.023
  
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sciencedirect.com/science/article/pii/S1534580723006214
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Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy

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1. scibot 07 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113529
  
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sciencedirect.com/science/article/pii/S2211124723015413
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YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113497
  
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Distinctive Interactomes of RNA polymerase II phosphorylation during different stages of transcription

1
1. scibot 01 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.107581
  
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52.53.155.43/e1f86bc1b78d4710d3685a727edad6313e1f1c49/1-s2.0-S2589004223016589-main-html.html
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cd-23-0299-html.html

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1. scibot 01 Dec 2023
  
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  DOI: 10.1158/2159-8290.cd-23-0299
  
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52.53.155.43/2b6c279d82b7a0e0d491057f5790a1189e93077e/cd-23-0299-html.html
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Protocol for establishing primary human lung organoid-derived air-liquid interface cultures from cryopreserved human lung tissue

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1. scibot 01 Dec 2023
  
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  DOI: 10.1016/j.xpro.2023.102735
  
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sciencedirect.com/science/article/pii/S2666166723007025
Nov 2023
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Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113496
  
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sciencedirect.com/science/article/pii/S2211124723015085
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Generation of four gene-edited human induced pluripotent stem cell lines with mutations in the ATM gene to model Ataxia-Telangiectasia

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1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.scr.2023.103247
  
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sciencedirect.com/science/article/pii/S1873506123002337
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Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis

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1. scibot 15 Nov 2023
  
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  DOI: 10.1038/s41556-023-01273-y
  
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nature.com/articles/s41556-023-01273-y
onlinelibrary.wiley.com onlinelibrary.wiley.com

Comparative neuroanatomy of the central nervous system in web-building and cursorial hunting spiders

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1. scibot 12 Nov 2023
  
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  DOI: 10.1002/cne.25554
  
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onlinelibrary.wiley.com/doi/10.1002/cne.25554
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Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination in male mice

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1. scibot 09 Nov 2023
  
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  DOI: 10.1038/s41467-023-42752-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10625541/
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Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq

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1. scibot 09 Nov 2023
  
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  DOI: 10.1016/j.crmeth.2023.100598
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10626193/
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Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1

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1. scibot 03 Nov 2023
  
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  DOI: 10.1101/2023.10.23.563657
  
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biorxiv.org/content/10.1101/2023.10.23.563657v1
Oct 2023
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The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.devcel.2023.10.002
  
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Deep scRNA sequencing reveals a broadly applicable Regeneration Classifier and implicates antioxidant response in corticospinal axon regeneration

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.neuron.2023.09.019
  
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Intravital microscopy of satellite cell dynamics and their interaction with myeloid cells during skeletal muscle regeneration

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1. scibot 20 Oct 2023
  
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  DOI: 10.1126/sciadv.adi1891
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10584350/
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Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism

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1. scibot 20 Oct 2023
  
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  DOI: 10.4103/1673-5374.380906
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10581554/
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Reciprocal transmission of activating and inhibitory signals and cell fate in regenerating T cells

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113155
  
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  DOI: 10.1016/j.celrep.2023.113155
  
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Microvascular smooth muscle cells exhibit divergent phenotypic switching responses to platelet-derived growth factor and insulin-like growth factor 1

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1. scibot 06 Oct 2023
  
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  DOI: 10.1016/j.mvr.2023.104609
  
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sciencedirect.com/science/article/pii/S0026286223001358
www.embopress.org www.embopress.org

Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth

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  DOI: 10.15252/embj.2023114032
  
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embopress.org/doi/10.15252/embj.2023114032
Sep 2023
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Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113166
  
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Thalamocortical control of cell-type specificity drives circuits for processing whisker-related information in mouse barrel cortex

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1. scibot 29 Sep 2023
  
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  DOI: 10.1038/s41467-023-41749-x
  
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nature.com/articles/s41467-023-41749-x
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Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia

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1. scibot 29 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107374
  
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Distinctive Interactomes of RNA polymerase II phosphorylation during different stages of transcription

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1. scibot 02 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107581
  
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52.53.155.43/e1f86bc1b78d4710d3685a727edad6313e1f1c49/1-s2.0-S2589004223016589-main-html.html
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors

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1. scibot 26 Aug 2023
  
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  DOI: 10.1016/j.chembiol.2023.06.029
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10437005/
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Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling

2
1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112984
  
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2. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112984
  
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Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis

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1. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107626
  
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PIIS2211124723009543-html.html

1
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  DOI: 10.1016/j.celrep.2023.112943
  
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Senescent cells form nuclear foci that contain the 26S proteasome

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  DOI: 10.1016/j.celrep.2023.112880
  
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Exosomal release of the virus-encoded chemokine receptor US28 contributes to chemokine scavenging

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Golgi polarity shift instructs dendritic refinement in the neonatal cortex by mediating NMDA receptor signaling

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Glycosaminoglycans and fucoidan have a protective effect on experimental glomerulonephritis

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1. scibot 21 Jul 2023
  
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  DOI: 10.3389/fmolb.2023.1223972
  
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A Novel Ex Vivo Model to Study Therapeutic Treatments for Myelin Repair following Ischemic Damage

1
1. scibot 15 Jul 2023
  
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  DOI: 10.3390/ijms241310972
  
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Macrophages drive KSHV B cell latency

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  DOI: 10.1016/j.celrep.2023.112767
  
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Imbalance of helper T cell subtypes and adipokine secretion in perivascular adipose tissue as a trigger of atherosclerosis in chronic Porphyromonas gingivalis W83 infection

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  DOI: 10.1016/j.micinf.2023.105181
  
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Jun 2023
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Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice

1
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Selective Block of Upregulated Kv1.3 Potassium Channels in ON-Bipolar Cells of the Blind Retina Enhances Optogenetically Restored Signaling

1
1. scibot 30 Jun 2023
  
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  DOI: 10.20944/preprints202305.0848.v1
  
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Fluorescence-microscopy-based assay assessing regulatory mechanisms of global genome nucleotide excision repair in cultured cells

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Cyclophosphamide induces the loss of taste bud innervation in mice

1
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  DOI: 10.1101/2023.06.14.544942
  
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Genetic ablation of Saposin-D in Krabbe disease eliminates psychosine accumulation but does not significantly improve demyelination

1
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The Rab5 effector FERRY links early endosomes with mRNA localization

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  DOI: 10.1016/j.molcel.2023.05.012
  
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May 2023
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Isolation and Characterization of Adult Cardiac Fibroblasts and Myofibroblasts

1
1. scibot 31 May 2023
  
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Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma

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  DOI: 10.1016/j.ccell.2023.04.017
  
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Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair

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  DOI: 10.1126/sciadv.add8023
  
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Drosophila Tachykininergic Neurons Modulate the Activity of Two Groups of Receptor-Expressing Neurons to Regulate Aggressive Tone

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  DOI: 10.1523/JNEUROSCI.1734-22.2023
  
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Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair

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Ubiquitin proteomics identifies RNA polymerase I as a target of the Smc5/6 complex

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Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice

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Immune mechanisms shape the clonal landscape during early progression of prostate cancer

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The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging

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Unidirectional and phase-gated signaling synchronizes murine presomitic mesoderm cells

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The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation

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Mechanism of interdigitation formation at apical boundary of MDCK cell

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Brain-specific glycosylation of protein tyrosine phosphatase receptor type Z (PTPRZ) marks a demyelination-associated astrocyte subtype

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Sodium ion influx regulates liquidity of biomolecular condensates in hyperosmotic stress response

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A timer gene network is spatially regulated by the terminal system in the Drosophila embryo

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  DOI: 10.7554/eLife.78902
  
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Mar 2023
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The protective effects of a novel AT2 receptor agonist, β-Pro7Ang III in ischemia-reperfusion kidney injury

1
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Multiplex translaminar imaging in the spinal cord of behaving mice

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  DOI: 10.1038/s41467-023-36959-2
  
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Neprilysin-sensitive amyloidogenic Aβ versus IDE-sensitive soluble Aβ: a probable mechanistic cause for sporadic Alzheimer’s disease

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  DOI: 10.1101/2021.08.22.457281
  
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Non-muscle myosin II drives critical steps of nematocyst morphogenesis

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  DOI: 10.1016/j.isci.2023.106291
  
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Simultaneous activation of Tor and suppression of ribosome biogenesis by TRIM-NHL proteins promotes terminal differentiation

1
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  DOI: 10.1016/j.celrep.2023.112181
  
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Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye

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Seeking the Amygdala: Novel Use of Diffusion Tensor Imaging to Delineate the Basolateral Amygdala

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RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex

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Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology

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Characterization of the structure and control of the blood-nerve barrier identifies avenues for therapeutic delivery

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A single RET mutation in Hirschsprung disease induces intestinal aganglionosis via a dominant-negative mechanism

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Teriflunomide as a therapeutic means for myelin repair

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Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance

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A porcine islet-encapsulation device that enables long-term discordant xenotransplantation in immunocompetent diabetic mice

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Neural precursor cells tune striatal connectivity through the release of IGFBPL1

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Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals

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Single cell sequencing maps skeletal muscle cellular diversity as disease severity increases in dystrophic mouse models

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Cellular mechanisms underlying central sensitization in a mouse model of chronic muscle pain

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Cephalopod retinal development shows vertebrate-like mechanisms of neurogenesis

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NEIL3 contributes to the Fanconi anemia/BRCA pathway by promoting the downstream double-strand break repair step

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Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ

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Continuous double-strand break induction and their differential processing sustain chiasma formation during Caenorhabditis elegans meiosis

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RIPOR2-mediated autophagy dysfunction is critical for aminoglycoside-induced hearing loss

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Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells

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Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis

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CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair

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Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons

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Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock

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Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations

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Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides

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A neural progenitor mitotic wave is required for asynchronous axon outgrowth and morphology

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Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging

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Infarct-preconditioning exosomes of umbilical cord mesenchymal stem cells promoted vascular remodeling and neurological recovery after stroke in rats

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Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection

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A quantitative biophysical principle to explain the 3D cellular connectivity in curved epithelia

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Ubiquitin profiling of lysophagy identifies actin stabilizer CNN2 as a target of VCP/p97 and uncovers a link to HSPB1

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Antennapedia and optix regulate metallic silver wing scale development and cell shape in Bicyclus anynana butterflies

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Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes

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Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma

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Langerhans cells are an essential cellular intermediary in chronic dermatitis

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The ER ladder is a unique morphological feature of developing mammalian axons

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Ribbon boosts ribosomal protein gene expression to coordinate organ form and function

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Genetic deletion of the glucocorticoid receptor in Cx3cr1+ myeloid cells is neuroprotective and improves motor recovery after spinal cord injury

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Abelson tyrosine-protein kinase 2 regulates myoblast proliferation and controls muscle fiber length

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Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells

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Optimized Protocol for Proportionate CNS Cell Retrieval as a Versatile Platform for Cellular and Molecular Phenomapping in Aging and Neurodegeneration

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Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity

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Xeno-free culture for generation of forebrain oligodendrocyte precursor cells from human pluripotent stem cells

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Hypertrophic chondrocytes serve as a reservoir for marrow-associated skeletal stem and progenitor cells, osteoblasts, and adipocytes during skeletal development

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Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration

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In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation

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Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop

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Uhrf1 governs the proliferation and differentiation of muscle satellite cells

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Generation of a GPR146 knockout human induced pluripotent stem cell line (ITXi001-A-1)

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Full-length and split-NanoLuc reporters identify pathogenic COL4A5 nonsense mutations susceptible to premature termination codon readthrough

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Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion

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Neuron-derived neuropeptide Y fine-tunes the splenic immune responses

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Protocol for generating a mouse model of gastric MALT lymphoma and the identification of MALT lymphoma cell populations by immunostaining

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Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice

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Two Functional Classes of Rod Bipolar Cells in the Healthy and Degenerated Optogenetically Treated Murine Retina

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Serotonergic neurons translate taste detection into internal nutrient regulation

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The Calcitonin Receptor Protects Against Bone Loss and Excessive Inflammation in Collagen Antibody-Induced Arthritis

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APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain

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Sex differences in embryonic gonad transcriptomes and benzo[a]pyrene metabolite levels after transplacental exposure

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TLR4 Associated Signaling Disrupters as a New Means to Overcome HERV-W Envelope-Mediated Myelination Deficits

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The asymmetric Pitx2 gene regulates gut muscular-lacteal development and protects against fatty liver disease

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Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction

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The rates of stem cell division determine the cell cycle lengths of its lineage

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A human ESC line for efficient CRISPR editing of pluripotent stem cells

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Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing

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Marker-free lineage tracing reveals an environment-instructed clonogenic hierarchy in pancreatic cancer

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Opposing motors provide mechanical and functional robustness in the human spindle

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Uterine epithelial LIF receptors contribute to implantation chamber formation in blastocyst attachment

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Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing

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The TLR4–TRIF–type 1 IFN–IFN-γ pathway is crucial for gastric MALT lymphoma formation after Helicobacter suis infection

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Revisiting astrocyte to neuron conversion with lineage tracing in vivo

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SUMOylation of RepoMan during late telophase regulates dephosphorylation of lamin A

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The postnatal pancreatic microenvironment guides β cell maturation through BMP4 production

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Alzheimer's Aβ assembly binds sodium pump and blocks endothelial NOS activity via ROS-PKC pathway in brain vascular endothelial cells

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Activating a collaborative innate-adaptive immune response to control metastasis

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ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability

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Enhanced Multiplexing of Immunofluorescence Microscopy Using a Long-Stokes-Shift Fluorophore

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Intestinal microbiota modulates adrenomedullary response through Nod1 sensing in chromaffin cells

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Diffusion-mediated HEI10 coarsening can explain meiotic crossover positioning in Arabidopsis

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Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila

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Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function

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Evolution of Ovipositor Length in Drosophila suzukii Is Driven by Enhanced Cell Size Expansion and Anisotropic Tissue Reorganization

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KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia

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α-Ketoglutarate links p53 to cell fate during tumour suppression

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T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

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Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis

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Standard screening methods underreport AAV-mediated transduction and gene editing

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Quantitative Clonal Analysis and Single-Cell Transcriptomics Reveal Division Kinetics, Hierarchy, and Fate of Oral Epithelial Progenitor Cells

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  DOI: 10.1016/j.celrep.2018.08.067
  
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Adult-born neurons facilitate olfactory bulb pattern separation during task engagement

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  DOI: 10.7554/eLife.33006
  
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Evolution of Ovipositor Length in Drosophila suzukii Is Driven by Enhanced Cell Size Expansion and Anisotropic Tissue Reorganization

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  DOI: 10.1016/j.celrep.2018.09.056
  
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Protandim Protects Oligodendrocytes against an Oxidative Insult

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  AB_10561520
  
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Region specific oligodendrocyte transcription factor expression in a model of neonatal hypoxic injury

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  DOI: 10.1016/j.ijdevneu.2017.05.001
  
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Retinal ganglion cell survival and axon regeneration after optic nerve injury in naked mole‐rats

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  AB_2534074
  
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Molecular cell identities in the mediodorsal thalamus of infant mice and marmoset

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EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart

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Protein-based condensation mechanisms drive the assembly of RNA-rich P granules

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Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy

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Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration

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Neonatal susceptibility to meningitis results from the immaturity of epithelial barriers and gut microbiota

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Generation of two human iPSC lines from patients with autosomal dominant retinitis pigmentosa (UCLi014-A) and autosomal recessive Leber congenital amaurosis (UCLi015-A), associated with RDH12 variants

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Involvement of cerebellar neural circuits in active avoidance conditioning in zebrafish

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  DOI: 10.1523/ENEURO.0507-20.2021
  
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NLRP3 Regulates IL-4 Expression in TOX+ CD4+ T Cells of Cutaneous T Cell Lymphoma to Potentially Promote Disease Progression

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  DOI: 10.3389/fimmu.2021.668369
  
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Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation

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  DOI: 10.1016/j.isci.2021.102660
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8209278/

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