326 Matching Annotations
  1. Jan 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BCAT1 combined with α-ketoglutarate triggers metabolic synthetic lethality in glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9256772/
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    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
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    sciencedirect.com/science/article/pii/S1934590922004908
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    Axonal plasticity in response to active forces generated through magnetic nano-pulling
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    sciencedirect.com/science/article/pii/S2211124722018113
  5. Nov 2022
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    m6A-modified lincRNA Dubr is required for neuronal development by stabilizing YTHDF1/3 and facilitating mRNA translation
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    sciencedirect.com/science/article/pii/S2211124722015674
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    Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
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    sciencedirect.com/science/article/pii/S1550413122004892
  8. Oct 2022
  9. elifesciences.org elifesciences.org
    GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
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    elifesciences.org/articles/81083
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    Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities
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    ncbi.nlm.nih.gov/pmc/articles/PMC9552079/
  11. Jul 2022
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    Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging
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    sciencedirect.com/science/article/pii/S2211124722009378
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    GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
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    sciencedirect.com/science/article/pii/S1550413122002303
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    Neuron-specific translational control shift ensures proteostatic resilience during ER stress
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    embopress.org/doi/10.15252/embj.2021110501
  15. Jun 2022
  16. 52.53.155.43 52.53.155.43
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    Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9218363/
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    pSNAP: Proteome-wide analysis of elongating nascent polypeptide chains
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    sciencedirect.com/science/article/pii/S2589004222007878
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    Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals
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    sciencedirect.com/science/article/pii/S0896627322005013
  20. May 2022
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    Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes
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    sciencedirect.com/science/article/pii/S2211124722006337
  22. Apr 2022
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    CLOCK regulates Drp1 mRNA stability and mitochondrial homeostasis by interacting with PUF60
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    sciencedirect.com/science/article/pii/S2211124722003874
  24. Feb 2022
  25. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TBK1-METTL3 axis facilitates antiviral immunity
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  26. Dec 2021
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    RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth
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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
  29. www.mdpi.com www.mdpi.com
    Disruption of Circadian Rhythms by Ambient Light during Neurodevelopment Leads to Autistic-like Molecular and Behavioral Alterations in Adult Mice
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    mdpi.com/2073-4409/10/12/3314/htm
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8605100/
  31. Nov 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly
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    ncbi.nlm.nih.gov/pmc/articles/PMC8598234/
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    mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion
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    elifesciences.org/articles/69015
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    RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
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    sciencedirect.com/science/article/pii/S2211124721014078
  35. Sep 2021
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    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
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    Increased fidelity of protein synthesis extends lifespan
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    Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation
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    A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2′3′-cGAMP
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    sciencedirect.com/science/article/pii/S2451945621003950
  40. Aug 2021
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    Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
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    Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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  51. Jul 2021
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    The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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    Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers
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    RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo
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    sciencedirect.com/science/article/pii/S0896627317306384
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  57. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
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    currentprotocols.onlinelibrary.wiley.com/doi/full/10.1002/cptx.56
  58. www.cell.com www.cell.com
    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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    cell.com/molecular-cell/fulltext/S1097-2765(21)00493-7
  59. Jun 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Pumilio2 and Staufen2 selectively balance the synaptic proteome
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    sciencedirect.com/science/article/pii/S221112472100646X
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    Bacterial RF3 senses chaperone function in co-translational folding
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  62. May 2021
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    Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress
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    PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation
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    sciencedirect.com/science/article/pii/S1097276521000526
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    Axon-enriched lincRNA ALAE is required for axon elongation via regulation of local mRNA translation
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    sciencedirect.com/science/article/pii/S2211124721003697
  66. Apr 2021
  67. www.sciencedirect.com www.sciencedirect.com
    Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis
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  68. www.sciencedirect.com www.sciencedirect.com
    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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    sciencedirect.com/science/article/pii/S1097276521001775
  69. Feb 2021
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Bicuculline regulated protein synthesis is dependent on homer1 and promotes its interaction with eEF2K through mTORC1 dependent phosphorylation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15178
  71. www.cell.com www.cell.com
    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30827-3
  72. Jan 2021
  73. www.jneurosci.org www.jneurosci.org
    The Integrated UPR and ERAD in Oligodendrocytes Maintain Myelin Thickness in Adults by Regulating Myelin Protein Translation
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    jneurosci.org/content/40/43/8214
  74. Dec 2020
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans
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    ncbi.nlm.nih.gov/pmc/articles/PMC7746234/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation in amino-acid-poor environments is limited by tRNAGln charging
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    ncbi.nlm.nih.gov/pmc/articles/PMC7744096/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes
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    ncbi.nlm.nih.gov/pmc/articles/PMC6957384/
  78. Nov 2020
  79. www.sciencedirect.com www.sciencedirect.com
    ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B
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    Unbiased Proteomic Screening Identifies a Novel Role for the E3 Ubiquitin Ligase Nedd4‐2 in Translational Suppression During ER Stress
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15219
  81. Sep 2020
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    Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity
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  83. elifesciences.org elifesciences.org
    Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes
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    elifesciences.org/articles/60048
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    The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress
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    Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States
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  86. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression
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    cancerres.aacrjournals.org/content/80/17/3706
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    ZAKα Recognizes Stalled Ribosomes through Partially Redundant Sensor Domains
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    RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation
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    Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons
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    cell.com/cell/abstract/S0092-8674(18)31555-1
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    Non-Canonical Caspase Activity Antagonizes p38 MAPK Stress-Priming Function to Support Development
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    Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7272217/
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    UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1
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    sciencedirect.com/science/article/pii/S096098221931615X
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    Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway
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    pnas.org/content/117/30/17842
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    Inter-dependent Centrosomal Co-localization of the cen and ik2 cis-Natural Antisense mRNAs in Drosophila
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  96. journals.physiology.org journals.physiology.org
    Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes | American Journal of Physiology-Cell Physiology
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    journals.physiology.org/doi/full/10.1152/ajpcell.00148.2019
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    Redefining Single-Trial Memories in the Honeybee
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    Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR
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  99. Jan 2020
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    Early Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC
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    RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs
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    Concerted 2-5A-Mediated mRNA Decay and Transcription Reprogram Protein Synthesis in the dsRNA Response
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    CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation
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    The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma
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  105. www.nature.com www.nature.com
    eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma
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    nature.com/articles/s41467-019-13086-5
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    On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons
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    CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation
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    An ECM-to-Nucleus Signaling Pathway Activates Lysosomes for C. elegans Larval Development
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    Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration
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    Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
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