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  1. Feb 2023
  2. aacrjournals.org aacrjournals.org
    Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells
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    aacrjournals.org/cancerdiscovery/article/13/2/474/716294/Bone-Metastasis-Initiation-Is-Coupled-with-Bone
  3. www.sciencedirect.com www.sciencedirect.com
    Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model
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    sciencedirect.com/science/article/pii/S2589004223001700
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    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
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    sciencedirect.com/science/article/pii/S1534580723000370
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    Lymphatic vessels in bone support regeneration after injury
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    1. scibot 14 Feb 2023
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    sciencedirect.com/science/article/pii/S0092867422015744
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Pro-Regenerative Environment Triggers Premalignant to Malignant Transformation of Senescent Hepatocytes
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    1. scibot 11 Feb 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC9896023/
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    Structural and functional integration of human forebrain organoids with the injured adult rat visual system
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    sciencedirect.com/science/article/pii/S1934590923000048
  8. Jan 2023
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    Multi-omics profiling visualizes dynamics of cardiac development and functions
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    1. scibot 28 Jan 2023
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    sciencedirect.com/science/article/pii/S2211124722017909
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    An in vivo avian model of human melanoma to perform rapid and robust preclinical studies
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      DOI: 10.15252/emmm.202216629

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    embopress.org/doi/10.15252/emmm.202216629
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    S-adenosylmethionine blocks tumorigenesis and with immune checkpoint inhibitor enhances anti-cancer efficacy against BRAF mutant and wildtype melanomas
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    sciencedirect.com/science/article/pii/S1476558622000999
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Trisomy 21 induces pericentrosomal crowding delaying primary ciliogenesis and mouse cerebellar development
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    1. scibot 22 Jan 2023
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      DOI: 10.7554/eLife.78202

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    ncbi.nlm.nih.gov/pmc/articles/PMC9851619/
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    Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway
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    sciencedirect.com/science/article/pii/S2211124723000141
  14. journals.lww.com journals.lww.com
    Metformin promotes angiogenesis and functional recovery in... : Neural Regeneration Research
    1
    1. scibot 19 Jan 2023
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    journals.lww.com/nrronline/Fulltext/2023/07000/Metformin_promotes_angiogenesis_and_functional.30.aspx
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Augmenting Experimental Gastric Cancer Activity of Irinotecan through Liposomal Formulation and Antiangiogenic Combination Therapy
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    1. scibot 12 Jan 2023
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    Resurrection of endogenous retroviruses during aging reinforces senescence
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    1. scibot 07 Jan 2023
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    sciencedirect.com/science/article/pii/S0092867422015306
  17. Dec 2022
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling
    1
    1. scibot 31 Dec 2022
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      DOI: 10.3390/pharmaceutics14122774

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    ncbi.nlm.nih.gov/pmc/articles/PMC9781674/
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    An insulin hypersecretion phenotype precedes pancreatic β cell failure in MODY3 patient-specific cells
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    1. scibot 24 Dec 2022
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    sciencedirect.com/science/article/pii/S1934590922004854
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    In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution
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    1. scibot 20 Dec 2022
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    sciencedirect.com/science/article/pii/S2667237522002697
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    An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair
    1
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    sciencedirect.com/science/article/pii/S1934590922004593
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐67
    1
    1. scibot 13 Dec 2022
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      DOI: 10.15252/embr.202255782

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    ncbi.nlm.nih.gov/pmc/articles/PMC9724667/
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    Maternal fiber deprivation alters microbiota in offspring, resulting in low-grade inflammation and predisposition to obesity
    1
    1. scibot 11 Dec 2022
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    sciencedirect.com/science/article/pii/S1931312822005273
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    miR-17∼92 exerts stage-specific effects in adult V-SVZ neural stem cell lineages
    1
    1. scibot 08 Dec 2022
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    sciencedirect.com/science/article/pii/S2211124722016564
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    m6A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina
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    1. scibot 06 Dec 2022
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      DOI: 10.7554/eLife.79994

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    ncbi.nlm.nih.gov/pmc/articles/PMC9718531/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cellular and molecular effects of PNCK, a non-canonical kinase target in renal cell carcinoma
    1
    1. scibot 04 Dec 2022
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    ncbi.nlm.nih.gov/pmc/articles/PMC9713373/
  27. 52.53.155.43 52.53.155.43
    cd-22-0220-html.html
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  28. aacrjournals.org aacrjournals.org
    Depletion of conventional type-1 dendritic cells in established tumors suppresses immunotherapy efficacy
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      DOI: 10.1158/0008-5472.CAN-22-1046

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    aacrjournals.org/cancerres/article/82/23/4373/710691/Depletion-of-Conventional-Type-1-Dendritic-Cells
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topical Wound Treatment with a Nitric Oxide-Releasing PDE5 Inhibitor Formulation Enhances Blood Perfusion and Promotes Healing in Mice
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      DOI: 10.3390/pharmaceutics14112358

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    ncbi.nlm.nih.gov/pmc/articles/PMC9696390/
  30. 52.53.155.43 52.53.155.43
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  31. Nov 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Activation of Wnt/β-catenin signaling by Zeb1 in endothelial progenitors induces vascular quiescence entry
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    sciencedirect.com/science/article/pii/S2211124722015686
  33. academic.oup.com academic.oup.com
    Effect of inactivation of Mst1 and Mst2 in the mouse adrenal cortex
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    1. scibot 19 Nov 2022
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      DOI: 10.1210/jendso/bvac143

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    academic.oup.com/jes/article/7/1/bvac143/6702160
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    Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379122003743
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    Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling
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    sciencedirect.com/science/article/pii/S2211124722014462
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    Integration of single-cell transcriptome and chromatin accessibility of early gonads development among goats, pigs, macaques, and humans
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    sciencedirect.com/science/article/pii/S2211124722014528
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deletion of Nox4 enhances remyelination following cuprizone-induced demyelination by increasing phagocytic capacity of microglia and macrophages in mice
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  38. Oct 2022
  39. www.sciencedirect.com www.sciencedirect.com
    TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preservation effect of imeglimin on pancreatic β-cell mass: Noninvasive evaluation using 111In-exendin-4 SPECT/CT imaging and the perspective of mitochondrial involvements
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    BCAT1 redox function maintains mitotic fidelity
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    sciencedirect.com/science/article/pii/S2211124722013791
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    A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1
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    sciencedirect.com/science/article/pii/S2211124722013250
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    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
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    sciencedirect.com/science/article/pii/S1097276522008966
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    Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization
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      DOI: 10.1016/j.chembiol.2022.09.002

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    sciencedirect.com/science/article/pii/S2451945622003506
  45. Sep 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Microglial control of neuronal development via somatic purinergic junctions
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tenascin-C fibronectin D domain is involved in the fine-tuning of glial response to CNS injury in vitro
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    BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer
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    Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development
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    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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  52. Aug 2022
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    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
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    The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth
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    The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells
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    Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy
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    Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock
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    Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice
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    Multifocal organoids reveal clonal associations between synchronous intestinal tumors with pervasive heterogeneous drug responses
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    PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis
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    Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells
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    Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
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    Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal β cells
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    Beta-blockers disrupt mitochondrial bioenergetics and increase radiotherapy efficacy independently of beta-adrenergic receptors in medulloblastoma
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    Lanthionine Ketimine Ethyl Ester Accelerates Remyelination in a Mouse Model of Multiple Sclerosis - Jeffrey L. Dupree, Pablo M. Paez, Seema K. Tiwari-Woodruff, Travis T. Denton, Kenneth Hensley, Christina G. Angeliu, Anne I. Boullerne, Sergey Kalinin, Sophia Egge, Veronica T. Cheli, Giancarlo Denaroso, Kelley C. Atkinson, Micah Feri, Douglas L. Feinstein, 2022
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    Disruption of endosomal sorting in Schwann cells leads to defective myelination and endosomal abnormalities observed in Charcot-Marie-Tooth disease
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    Grafted human ESC-derived astroglia repair spinal cord injury via activation of host anti-inflammatory microglia in the lesion area
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    Progression Patterns in Non-Contrast-Enhancing Gliomas Support Brain Tumor Responsiveness to Surgical Lesions
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    Liver Endothelium Promotes HER3-mediated Cell Survival in Colorectal Cancer with Wild-type and Mutant KRAS
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    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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  78. May 2022
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    Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
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    Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging
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    An injury-responsive Rac-to-Rho GTPase switch drives activation of muscle stem cells through rapid cytoskeletal remodeling
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    Bi-zonal cardiac engineered tissues with differential maturation features in a mid-throughput multimodal bioreactor
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    JAM-A Signals Through the Hippo Pathway to Regulate Intestinal Epithelial Proliferation
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    5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis
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    Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization
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    RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development
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    miRNA/mRNA co-profiling identifies the miR-200 family as a central regulator of SMC quiescence
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    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
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    Oligodendrocytes control potassium accumulation in white matter and seizure susceptibility
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    Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
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    A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration
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    Evolutionary conservation of centriole rotational asymmetry in the human centrosome
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43
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  96. Mar 2022
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    Coactivator-associated arginine methyltransferase 1 controls oligodendrocyte differentiation in the corpus callosum during early brain development
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    A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
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    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
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    A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair
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    Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter
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    A novel Lgi1 mutation causes white matter abnormalities and impairs motor coordination in mice
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    Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability
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    Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L
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    miR-137 and miR-122, two outer subventricular zone non-coding RNAs, regulate basal progenitor expansion and neuronal differentiation
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    Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration
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  116. Jan 2022
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    Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate-Glutamate Carrier Isoform 1 Deficiency
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    Lipid droplet dynamics regulate adult muscle stem cell fate
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    Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity
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    Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness
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  124. Dec 2021
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    Preventive effect of sanguinarine on intestinal injury in mice exposed to whole abdominal irradiation
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    Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity
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    Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses
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    Nasal obstruction during the growth period modulates the Wnt/β-Catenin pathway and brain-derived neurotrophic factor production in association with tyrosine kinase receptor B mRNA reduction in mouse hippocampus
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    Co-emergence of cardiac and gut tissues promotes cardiomyocyte maturation within human iPSC-derived organoids
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  136. Nov 2021
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    Oligodendrocyte progenitor proliferation is disinhibited following traumatic brain injury in leukemia inhibitory factor heterozygous mice
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  183. www.sciencedirect.com www.sciencedirect.com
    Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage
    1
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  185. www.sciencedirect.com www.sciencedirect.com
    Effects of Toll-like receptor 4 inhibition on spatial memory and cell proliferation in male and female adult and aged mice
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  186. elifesciences.org elifesciences.org
    Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ
    5
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  187. www.sciencedirect.com www.sciencedirect.com
    AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy
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  188. academic.oup.com academic.oup.com
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  189. Jul 2021
  190. www.nature.com www.nature.com
    Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis
    1
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      DOI: 10.1038/s41467-019-11327-1

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  191. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  192. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      anti‐Ki67

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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  194. www.jneurosci.org www.jneurosci.org
    The Divalent Metal Transporter 1 (DMT1) Is Required for Iron Uptake and Normal Development of Oligodendrocyte Progenitor Cells
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      DOI: 10.1523/JNEUROSCI.1447-18.2018

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  195. www.sciencedirect.com www.sciencedirect.com
    Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation
    1
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      DOI: 10.1016/j.stem.2019.06.011

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  196. journals.plos.org journals.plos.org
    Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner
    1
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      rabbit polyclonal anti-Ki67

      DOI: 10.1371/journal.pgen.1008254

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  197. academic.oup.com academic.oup.com
    Generation of Mouse for Conditional Expression of Forkhead Box A2
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      DOI: 10.1210/en.2018-00158

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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling
    2
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  199. www.sciencedirect.com www.sciencedirect.com
    Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells
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    sciencedirect.com/science/article/pii/S2211124719301834
  200. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Diosmetin induces apoptosis and enhances the chemotherapeutic efficacy of paclitaxel in non‐small cell lung cancer cells via Nrf2 inhibition
    1
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      anti‐Ki67

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  201. www.sciencedirect.com www.sciencedirect.com
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  202. academic.oup.com academic.oup.com
    Mutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic Therapy
    1
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      RRID:AB_443209

      DOI: 10.1210/en.2017-00111

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  203. elifesciences.org elifesciences.org
    A comprehensive analysis of coregulator recruitment, androgen receptor function and gene expression in prostate cancer
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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablation of proliferating neural stem cells during early life is sufficient to reduce adult hippocampal neurogenesis
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      RRID:AB_443209

      DOI: 10.1002/hipo.22962

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  206. elifesciences.org elifesciences.org
    Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ
    1
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      AB_443209

      DOI: 10.7554/eLife.21697

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  207. www.sciencedirect.com www.sciencedirect.com
    The Polyploid State Plays a Tumor-Suppressive Role in the Liver
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      AB_44320

      DOI: 10.1016/j.devcel.2018.01.010

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    sciencedirect.com/science/article/pii/S1534580718300108
  208. www.sciencedirect.com www.sciencedirect.com
    Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer
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      AB_44320

      DOI: 10.1016/j.ccell.2017.10.007

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  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms
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      RRID:AB_443209

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    ncbi.nlm.nih.gov/pmc/articles/PMC8261663/
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis
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      RRID:AB_443209

      DOI: 10.1111/bph.15438

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  211. www.sciencedirect.com www.sciencedirect.com
    Regional specialization and fate specification of bone stromal cells in skeletal development
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      RRID:AB_443209

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  212. www.cell.com www.cell.com
    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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      RRID:AB_443209

      DOI: 10.1016/j.molcel.2021.06.014

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  213. Jun 2021
  214. academic.oup.com academic.oup.com
    CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice
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      RRID:AB_443209

      DOI: 10.1210/endocr/bqab064

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