309 Matching Annotations
  1. Jul 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Diverse mitochondrial abnormalities in a new cellular model of TAFFAZZIN deficiency are remediated by Cardiolipin-interacting small molecules
    1
    1. scibot 31 Jul 2021
      ab6721

      DOI: 10.1016/j.jbc.2021.101005

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    sciencedirect.com/science/article/pii/S0021925821008073
  3. www.nature.com www.nature.com
    Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice
    1
    1. scibot 30 Jul 2021
      goat anti-rabbit secondary antibody conjugated to HRP

      DOI: 10.1038/s41467-019-11866-7

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    nature.com/articles/s41467-019-11866-7
  4. www.jove.com www.jove.com
    Quantitative Immunoblotting of Cell Lines as a Standard to Validate Immunofluorescence for Quantifying Biomarker Proteins in Routine Tissue Samples
    1
    1. scibot 30 Jul 2021
      RRID:AB_955447

      DOI: 10.3791/58735

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    jove.com/video/58735/quantitative-immunoblotting-cell-lines-as-standard-to-validate
  5. academic.oup.com academic.oup.com
    Untitled document
    1
    1. scibot 30 Jul 2021
      RRID:AB_955447

      DOI: 10.1210/en.2018-00701

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    academic.oup.com/endo/article/160/1/169/5193467
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sleep deprivation impairs learning and memory by decreasing protein O‐GlcNAcylation in the brain of adult zebrafish
    1
    1. scibot 29 Jul 2021
      RRID:AB_955447

      DOI: 10.1096/fj.201901399RR

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    onlinelibrary.wiley.com/doi/10.1096/fj.201901399RR
  7. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neurons
    1
    1. scibot 29 Jul 2021
      RRID:AB_955447

      DOI: 10.1111/jnc.15448

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15448
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
    1
    1. scibot 28 Jul 2021
      RRID:AB_955447

      DOI: 10.1002/jnr.24357

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    onlinelibrary.wiley.com/doi/full/10.1002/jnr.24357
  9. www.sciencedirect.com www.sciencedirect.com
    Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
    1
    1. scibot 22 Jul 2021
      RRID:AB_955447

      DOI: 10.1016/j.cell.2021.06.028

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    sciencedirect.com/science/article/pii/S0092867421007960
  10. www.sciencedirect.com www.sciencedirect.com
    Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
    1
    1. scibot 22 Jul 2021
      RRID:AB_955447

      DOI: 10.1016/j.celrep.2021.109394

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    sciencedirect.com/science/article/pii/S2211124721007920
  11. www.sciencedirect.com www.sciencedirect.com
    A dynamic and multilocus metabolic regulation strategy using quorum-sensing-controlled bacterial small RNA
    1
    1. scibot 22 Jul 2021
      RRID:AB_955447

      DOI: 10.1016/j.celrep.2021.109413

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    sciencedirect.com/science/article/pii/S2211124721008263
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy
    1
    1. scibot 08 Jul 2021
      RRID:AB_955447

      DOI: 10.7554/eLife.66582

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    ncbi.nlm.nih.gov/pmc/articles/PMC8245133/
  13. Jun 2021
  14. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 25 Jun 2021
      RRID:AB_955447

      DOI: 10.1111/bph.15532

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15532
  15. www.sciencedirect.com www.sciencedirect.com
    Dietary supplementation of grape seed tannin extract stimulated testis development, changed fatty acid profiles and increased testis antioxidant capacity in pre-puberty hu lambs
    1
    1. scibot 22 Jun 2021
      RRID:AB_955

      DOI: 10.1016/j.theriogenology.2021.06.015

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      Curator comments: Goat Anti-Rabbit IgG - H&L Polyclonal antibody, Hrp Conjugated Abcam Cat# ab6721

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    sciencedirect.com/science/article/pii/S0093691X21002193
  16. journals.sagepub.com journals.sagepub.com
    Melatonin Protects Against Ischemic Brain Injury by Modulating PI3K/AKT Signaling Pathway via Suppression of PTEN Activity - Yuanyuan Ran, Lin Ye, Zitong Ding, Fuhai Gao, Shuiqing Yang, Boyan Fang, Zongjian Liu, Jianing Xi, 2021
    1
    1. scibot 19 Jun 2021
      RRID:AB_955447

      DOI: 10.1177/17590914211022888

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    journals.sagepub.com/doi/full/10.1177/17590914211022888
  17. www.sciencedirect.com www.sciencedirect.com
    In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development
    1
    1. scibot 18 Jun 2021
      RRID:AB_955447

      DOI: 10.1016/j.cub.2021.05.045

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    sciencedirect.com/science/article/pii/S0960982221007430
  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phenotypic differences in the inner ears of CBA/CaJ and C57BL/6J mice carrying missense and single base pair deletion mutations in the Cdh23 gene
    1
    1. scibot 17 Jun 2021
      RRID:AB_955447

      DOI: 10.1002/jnr.24905

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24905
  19. elifesciences.org elifesciences.org
    SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome patients
    1
    1. scibot 11 Jun 2021
      RRID:AB_955447

      DOI: 10.7554/eLife.67481

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    elifesciences.org/articles/67481
  20. www.sciencedirect.com www.sciencedirect.com
    Protocol for determining protein cysteine thiol redox status using western blot analysis
    1
    1. scibot 11 Jun 2021
      RRID:AB_955447

      DOI: 10.1016/j.xpro.2021.100566

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    sciencedirect.com/science/article/pii/S2666166721002732
  21. May 2021
  22. journals.physiology.org journals.physiology.org
    Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21
    1
    1. scibot 11 May 2021
      RRID:AB_955447

      DOI: 10.1152/ajpendo.00270.2020

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    journals.physiology.org/doi/abs/10.1152/ajpendo.00270.2020
  23. journals.physiology.org journals.physiology.org
    Improved recovery from skeletal muscle damage is largely unexplained by myofibrillar protein synthesis or inflammatory and regenerative gene expression pathways
    1
    1. scibot 11 May 2021
      RRID:AB_955447

      DOI: 10.1152/ajpendo.00454.2020

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    journals.physiology.org/doi/abs/10.1152/ajpendo.00454.2020
  24. www.sciencedirect.com www.sciencedirect.com
    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
    1
    1. scibot 10 May 2021
      RRID:AB_955447

      DOI: 10.1016/j.cell.2021.04.016

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    sciencedirect.com/science/article/pii/S0092867421004955
  25. www.sciencedirect.com www.sciencedirect.com
    The Dynamics of Transcriptional Activation by Hepatic Reprogramming Factors
    1
    1. scibot 07 May 2021
      RRID:AB_955447

      DOI: 10.1016/j.molcel.2020.07.012

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    sciencedirect.com/science/article/pii/S1097276520305025
  26. Apr 2021
  27. www.sciencedirect.com www.sciencedirect.com
    Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition
    1
    1. scibot 30 Apr 2021
      RRID:AB_955447

      DOI: 10.1016/j.cmet.2020.11.018

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    sciencedirect.com/science/article/pii/S1550413120306537
  28. www.sciencedirect.com www.sciencedirect.com
    Mapping of domain-mediated protein-protein interaction by SPOT peptide assay
    1
    1. scibot 28 Apr 2021
      RRID:AB_955447

      DOI: 10.1016/j.xpro.2021.100503

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    sciencedirect.com/science/article/pii/S2666166721002100
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long non-coding RNA PART1 predicts a poor prognosis and promotes the malignant progression of pancreatic cancer by sponging miR-122
    1
    1. scibot 22 Apr 2021
      RRID:AB_955447

      DOI: 10.1186/s12957-021-02232-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC8053290/
  30. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1
    1
    1. scibot 21 Apr 2021
      RRID:AB_955447

      DOI: 10.1016/j.celrep.2021.109010

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    sciencedirect.com/science/article/pii/S2211124721003247
  31. www.sciencedirect.com www.sciencedirect.com
    Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
    1
    1. scibot 17 Apr 2021
      RRID:AB_955447

      DOI: 10.1016/j.ccell.2020.04.017

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    sciencedirect.com/science/article/pii/S1535610820302166
  32. www.sciencedirect.com www.sciencedirect.com
    Zika virus NS1 affects the junctional integrity of human brain microvascular endothelial cells
    1
    1. scibot 16 Apr 2021
      RRID:AB_955447

      DOI: 10.1016/j.biochi.2020.06.011

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    sciencedirect.com/science/article/pii/S0300908420301516
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila
    1
    1. scibot 02 Apr 2021
      RRID:AB_955447

      DOI: 10.7554/eLife.58565

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    ncbi.nlm.nih.gov/pmc/articles/PMC8007214/
  34. Mar 2021
  35. www.tandfonline.com www.tandfonline.com
    Effects of the histone acetylase inhibitor C646 on growth and differentiation of adipose-derived stem cells
    2
    1. scibot 15 Mar 2021
      RRID: AB_955447

      DOI: 10.1080/15384101.2021.1876389

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    2. scibot 15 Mar 2021
      RRID:AB_955447

      DOI: 10.1080/15384101.2021.1876389

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    tandfonline.com/doi/abs/10.1080/15384101.2021.1876389
  36. www.sciencedirect.com www.sciencedirect.com
    Emerging role of embryo secretome in the paracrine communication at the implantation site: a proof of concept
    1
    1. scibot 15 Mar 2021
      RRID:AB_955447

      DOI: 10.1016/j.fertnstert.2020.10.058

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    sciencedirect.com/science/article/pii/S0015028220326303
  37. www.embopress.org www.embopress.org
    Plasmodium transcription repressor AP2‐O3 regulates sex‐specific identity of gene expression in female gametocytes
    1
    1. scibot 09 Mar 2021
      RRID:AB_955447

      DOI: 10.15252/embr.202051660

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    embopress.org/doi/abs/10.15252/embr.202051660
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy
    1
    1. scibot 09 Mar 2021
      RRID:AB_955447

      DOI: 10.1016/j.cell.2020.10.045

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    ncbi.nlm.nih.gov/pmc/articles/PMC7927154/
  39. Feb 2021
  40. www.sciencedirect.com www.sciencedirect.com
    R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
    1
    1. scibot 28 Feb 2021
      RRID:AB_955447

      DOI: 10.1016/j.molcel.2020.12.026

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    sciencedirect.com/science/article/pii/S1097276520309473
  41. academic.oup.com academic.oup.com
    Adrenomedullin-RAMP2 and -RAMP3 systems regulate cardiac homeostasis during cardiovascular stress
    1
    1. scibot 28 Feb 2021
      RRID:AB_955447

      DOI: 10.1210/endocr/bqab001

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    academic.oup.com/endo/article/162/3/bqab001/6066531
  42. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Polysialic acid in the rat brainstem and thoracolumbar spinal cord: Distribution, cellular location and comparison with mouse
    1
    1. scibot 25 Feb 2021
      RRID:AB_955447

      DOI: 10.1002/cne.24982

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    onlinelibrary.wiley.com/doi/10.1002/cne.24982
  43. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A small‐molecule CD44 dimerizing inhibitor for glioblastoma treatment
    1
    1. scibot 25 Feb 2021
      RRID:AB_955447

      DOI: 10.1111/bph.15030

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15030
  44. academic.oup.com academic.oup.com
    Prenylflavonoid icariin induces ERE-independent estrogenic responses in a tissue selective manner
    1
    1. scibot 24 Feb 2021
      AB_955447

      DOI: 10.1210/jendso/bvz025

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    academic.oup.com/jes/article/4/2/bvz025/5639774
  45. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 24 Feb 2021
      RRID:AB_955447

      DOI: 10.1111/bph.14887

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14887
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Physical Evidence on Desmin‐Lamin B Interaction
    1
    1. scibot 24 Feb 2021
      RRID:AB_955447

      DOI: 10.1002/cm.21651

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    onlinelibrary.wiley.com/doi/10.1002/cm.21651
  47. www.frontiersin.org www.frontiersin.org
    Factor H Is Bound by Outer Membrane-Displayed Carbohydrate Metabolism Enzymes of Extraintestinal Pathogenic Escherichia coli and Contributes to Opsonophagocytosis Resistance in Bacteria
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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RON Expression Mediates Lipopolysaccharide-Mediated Dendritic Cell Maturation via March-I
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  49. Jan 2021
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    Effect of a Freezing Medium Containing Melatonin on Markers of Pre-meiotic and Post-meiotic Spermatogonial Stem Cells (SSCs) After Transplantation in an Azoospermia Mouse Model Due to Testicular Torsion
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    Attenuation of Antiviral Immune Response Caused by Perturbation of TRIM25-Mediated RIG-I Activation under Simulated Microgravity
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  52. Dec 2020
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    Antagonistic Regulation by CPN60A and CLPC1 of TRXL1 that Regulates MDH Activity Leading to Plant Disease Resistance and Thermotolerance
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    Long non-coding RNA00844 inhibits MAPK signaling to suppress the progression of hepatocellular carcinoma by targeting AZGP1
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    Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes
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    Keratinocyte-Macrophage Crosstalk by the Nrf2/Ccl2/EGF Signaling Axis Orchestrates Tissue Repair
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  57. Sep 2020
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    Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells
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    Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway
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  60. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib
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    Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies
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    OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
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    The GATA Transcription Factor Gaf1 Represses tRNAs, Inhibits Growth, and Extends Chronological Lifespan Downstream of Fission Yeast TORC1
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    Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms
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  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of brain‐derived neurotrophic factor signaling in the basal forebrain reverses acute sleep deprivation‐induced fear memory impairments
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    Comparative exome sequencing reveals novel candidate genes for retinitis pigmentosa
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Analysis of KIT Gene Structural Mutations Causing the Porcine Dominant White Phenotype Using Genome Edited Mouse Models
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      DOI: 10.3389/fgene.2020.00138

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  68. journals.physiology.org journals.physiology.org
    Active vitamin D induces gene-specific hypomethylation in prostate cancer cells developing vitamin D resistance | American Journal of Physiology-Cell Physiology
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    Proteome-wide Prediction of Lysine Methylation Leads to Identification of H2BK43 Methylation and Outlines the Potential Methyllysine Proteome
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    HEARTBREAK Controls Post-translational Modification of INDEHISCENT to Regulate Fruit Morphology in Capsella
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      DOI: 10.1016/j.cub.2020.07.055

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    Monitoring the glycosylation of AMPA (α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole‐propionate )‐type glutamate receptors using specific antibodies reveals a novel regulatory mechanism of N‐glycosylation occupancy by molecular chaperones in Mice
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      DOI: 10.1111/jnc.14964

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  72. Jan 2020
  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of Notch1 signaling promotes neuronal differentiation and improves functional recovery in Spinal Cord injury through suppressing the activation of RhoA
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      DOI: 10.1111/jnc.14833

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    NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia
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    Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons
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    Valves Are a Conserved Feature of the Zebrafish Lymphatic System
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    N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor
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  78. elifesciences.org elifesciences.org
    Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands
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    Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb
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      DOI: 10.7554/eLife.48725

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    Sensory Axon Growth Requires Spatiotemporal Integration of CaSR and TrkB Signaling
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      DOI: 10.1523/JNEUROSCI.0027-19.2019

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    Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion
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  82. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.14845

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    p75 Neurotrophin Receptor Activation Regulates the Timing of the Maturation of Cortical Parvalbumin Interneuron Connectivity and Promotes Juvenile-like Plasticity in Adult Visual Cortex
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      DOI: 10.1523/JNEUROSCI.2881-18.2019

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    The Specific Inhibition of SOD1 Selectively Promotes Apoptosis of Cancer Cells via Regulation of the ROS Signaling Network
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      DOI: 10.1155/2019/9706792

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  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effect of metformin on myotube BCAA catabolism
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    The neuroprotective effect of fullerenols on a model of Parkinson’s disease in Drosophila melanogaster
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    Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells
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    Salidroside Protects Dopaminergic Neurons by Regulating the Mitochondrial MEF2D‐ND6 Pathway in the MPTP/MPP+‐Induced Model of Parkinson's Disease
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      DOI: 10.1111/jnc.14868

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  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glycogen metabolism is impaired in the brain of male type 2 diabetic Goto‐Kakizaki rats
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      DOI: 10.1002/jnr.24437

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  90. www.sciencedirect.com www.sciencedirect.com
    Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging
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      DOI: 10.1016/j.celrep.2019.04.114

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  91. www.nature.com www.nature.com
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      DOI: 10.1038/s41467-019-08787-w

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  92. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    High‐fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers
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      DOI: 10.1113/JP277353

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  93. www.sciencedirect.com www.sciencedirect.com
    Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation
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      DOI: 10.1016/j.neuron.2019.04.017

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  94. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.ccell.2019.04.007

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      DOI: 10.1016/j.immuni.2019.01.003

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  96. academic.oup.com academic.oup.com
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      DOI: 10.1210/en.2018-00701

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    Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells
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      DOI: 10.1016/j.cell.2019.03.013

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  98. www.sciencedirect.com www.sciencedirect.com
    METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation
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      DOI: 10.1016/j.molcel.2019.03.040

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  99. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  100. Nov 2018
  101. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    CXCL14, a Brown Adipokine that Mediates Brown-Fat-to-Macrophage Communication in Thermogenic Adaptation
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    Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets
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  106. link.springer.com link.springer.com
    β4GalT1 Mediates PPARγ N-Glycosylation to Attenuate Microglia Inflammatory Activation
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Fusarium graminearum Histone Acetyltransferases Are Important for Morphogenesis, DON Biosynthesis, and Pathogenicity
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  109. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Arginine Vasopressin Differentially Modulates GABAergic Synaptic Transmission onto Temperature‐Sensitive and ‐Insensitive Neurons in the Rat Preoptic Area
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  110. Nov 2017
  111. www.tandfonline.com www.tandfonline.com
    Neurotoxicity of alkylated polycyclic aromatic compounds in human neuroblastoma cells
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    Nitric Oxide Regulates Protein Methylation during Stress Responses in Plants
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  114. academic.oup.com academic.oup.com
    FoxO1 Promotes Mitophagy in the Podocytes of Diabetic Male Mice via the PINK1/Parkin Pathway
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    Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly
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  116. www.sciencedirect.com www.sciencedirect.com
    Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease
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    Hypochlorite converts cysteinyl-dopamine into a cytotoxic product: A possible factor in Parkinson's Disease
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Heterocyclic Compound CE-104 Enhances Spatial Working Memory in the Radial Arm Maze in Rats and Modulates the Dopaminergic System
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  119. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Prostaglandin E2 promotes neural proliferation and differentiation and regulates Wnt target gene expression
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