421 Matching Annotations
  1. Mar 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overlapping and distinct functions of SPT6, PNUTS, and PCF11 in regulating transcription termination
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    pmc.ncbi.nlm.nih.gov/articles/PMC11915507/
  3. www.sciencedirect.com www.sciencedirect.com
    PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD
    1
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    sciencedirect.com/science/article/pii/S0896627325001187
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of the PKCζ/JNK signaling pathway in regulating the development of femoral head necrosis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11884774/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ephrin A1 functions as a ligand of EGFR to promote EMT and metastasis in gastric cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11876641/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LPIN3 promotes colorectal cancer growth by dampening intratumoral CD8+ T cell effector function
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11883066/
  7. Feb 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CPT1A-mediated MFF succinylation promotes stemness maintenance in ovarian cancer stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11830779/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted detection of endogenous LINE-1 proteins and ORF2p interactions
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11800616/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ALKBH1-mediated N6-methyladenosine methylation of TRAF1 promotes osteosarcoma proliferation and metastasis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11815365/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GATA3-Driven ceRNA Network in Lung Adenocarcinoma Bone Metastasis Progression and Therapeutic Implications
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11816722/
  12. www.sciencedirect.com www.sciencedirect.com
    Synonymous mutations promote tumorigenesis by disrupting m6A-dependent mRNA metabolism
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    sciencedirect.com/science/article/pii/S0092867425000959
  13. Jan 2025
  14. www.nature.com www.nature.com
    Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening
    1
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    nature.com/articles/s41467-025-56282-2
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mesenchymal stromal cells promote the formation of lung cancer organoids via Kindlin-2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11715222/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive analysis of H3K27me3 LOCKs under different DNA methylation contexts reveal epigenetic redistribution in tumorigenesis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11748335/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    hnRNPU-mediated pathogenic alternative splicing drives gastric cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11705778/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NLRP3 promotes inflammatory signaling and IL-1β cleavage in acute lung injury caused by cell wall extract of Lactobacillus casei
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11706994/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11739382/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of KLF5 promotes ferroptosis via the ZEB1/HMOX1 axis to enhance sensitivity to oxaliplatin in cancer cells
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11743205/
  21. www.embopress.org www.embopress.org
    Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
    1
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    embopress.org/doi/10.1038/s44318-024-00290-3
  22. www.sciencedirect.com www.sciencedirect.com
    DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs
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    sciencedirect.com/science/article/pii/S2211124724015250
  23. Dec 2024
  24. www.cell.com www.cell.com
    Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine
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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00652-9
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct differentiation trajectories leave lasting impacts on gene regulation and function of V2a interneurons
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11642877/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glucose binds and activates NSUN2 to promote translation and epidermal differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11662651/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Minimizing DNA trapping while maintaining activity inhibition via selective PARP1 degrader
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    pmc.ncbi.nlm.nih.gov/articles/PMC11655542/
  28. www.sciencedirect.com www.sciencedirect.com
    Lnc-RAINY Regulates Genes Involved in Radiation Susceptibility Through DNA:DNA:RNA triplex-forming Interactions and has Tumor Therapeutic Potential in Lung Cancers
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    sciencedirect.com/science/article/pii/S2468054024001689
  29. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
    1
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    sciencedirect.com/science/article/pii/S235239642400495X
  30. Nov 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Epigenetic control of myogenic identity of human muscle stem cells in Duchenne muscular dystrophy
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    sciencedirect.com/science/article/pii/S2589004224025756
  32. www.sciencedirect.com www.sciencedirect.com
    Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms
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    sciencedirect.com/science/article/pii/S1074761324004941
  33. www.embopress.org www.embopress.org
    Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
    1
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    embopress.org/doi/10.1038/s44318-024-00290-3
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC11649922/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Biallelic loss-of-function variants in GON4L cause microcephaly and brain structure abnormalities
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11538285/
  36. www.jneurosci.org www.jneurosci.org
    Beyond Glycolysis: Aldolase A Is a Novel Effector in Reelin-Mediated Dendritic Development
    1
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    jneurosci.org/content/44/42/e0072242024
  37. Oct 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peptidoglycan-Chi3l1 interaction shapes gut microbiota in intestinal mucus layer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11458176/
  39. Sep 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interplay of FXN expression and lipolysis in white adipocytes plays a critical role in insulin sensitivity in Friedreich’s ataxia mouse model
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11350209/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fatty acid–binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10909654/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIK2 Controls the Homeostatic Character of the POMC Secretome Acutely in Response to Pharmacological ER Stress Induction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11430698/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mis-splicing of Mitotic Regulators Sensitizes SF3B1-Mutated Human HSCs to CHK1 Inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369594/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Ribosome Assembly Factor LSG1 Interacts with Vesicle-Associated Membrane Protein-Associated Proteins (VAPs)
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    ncbi.nlm.nih.gov/pmc/articles/PMC11376406/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    4EBP1-mediated SLC7A11 protein synthesis restrains ferroptosis triggered by MEK inhibitors in advanced ovarian cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383183/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC/H3K27ac-mediated transcription of NDUFA3 exerts protective effects on high glucose-treated human nucleus pulposus cells through improving mitochondrial function
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11387752/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel lncRNA GM47544 modulates triglyceride metabolism by inducing ubiquitination-dependent protein degradation of APOC3
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11399561/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of ACTN4 as a novel antiviral target against SARS-CoV-2
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11408661/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arpin deficiency increases actomyosin contractility and vascular permeability
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11412691/
  50. Aug 2024
  51. www.sciencedirect.com www.sciencedirect.com
    Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS
    1
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    sciencedirect.com/science/article/pii/S0896627324005701
  52. www.sciencedirect.com www.sciencedirect.com
    Engineering acyclovir-induced RNA nanodevices for reversible and tunable control of aptamer function
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    sciencedirect.com/science/article/pii/S2451945624003192
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular characteristics and oncogenic role of CHD family genes: a pan-cancer analysis based on bioinformatic and biological analysis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11324730/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11323502/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PINX1 loss confers susceptibility to PARP inhibition in pan-cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11341912/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spectrin mediates 3D-specific matrix stress-relaxation response in neural stem cell lineage commitment
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11296331/
  57. www.sciencedirect.com www.sciencedirect.com
    Acetate enables metabolic fitness and cognitive performance during sleep disruption
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    sciencedirect.com/science/article/pii/S1550413124002900
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exome-wide association study identifies KDELR3 mutations in extreme myopia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306401/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 nucleocapsid protein promotes self-deacetylation by inducing HDAC6 to facilitate viral replication
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321199/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MARCH2, a T cell specific factor that restricts HIV-1 infection
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11309421/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Muscle-Specific Pyruvate Kinase Isoforms, Pkm1 and Pkm2, Regulate Mammalian SWI/SNF Proteins and Histone 3 Phosphorylation During Myoblast Differentiation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11030359/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10935927/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTBP3/IGF2BP3/HMGA1 axis promotes renal cancer growth and metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10884747/
  64. Jul 2024
  65. www.cell.com www.cell.com
    Crosstalk between epitranscriptomic and epigenomic modifications and its implication in human diseases
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    cell.com/cell-genomics/fulltext/S2666-979X(24)00199-X
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages
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    ncbi.nlm.nih.gov/pmc/articles/PMC11217462/
  67. www.biorxiv.org www.biorxiv.org
    Nuclear receptor E75/NR1D2 drives tumor malignant transformation by integrating Hippo and Notch pathways
    1
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    biorxiv.org/content/10.1101/2024.06.27.600913v1
  68. Jun 2024
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miR-200-mediated inactivation of cancer-associated fibroblasts via targeting of NRP2-VEGFR signaling attenuates lung cancer invasion and metastasis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11101731/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11160645/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148184/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O-GlcNAcylation regulates the stability of transferrin receptor (TFRC) to control the ferroptosis in hepatocellular carcinoma cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11103954/
  73. www.biorxiv.org www.biorxiv.org
    Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening
    1
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    biorxiv.org/content/10.1101/2024.05.30.596755v1
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanical activation of VE-cadherin stimulates AMPK to increase endothelial cell metabolism and vasodilation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11118335/
  75. www.sciencedirect.com www.sciencedirect.com
    CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer
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    sciencedirect.com/science/article/pii/S0304383524004002
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of Bivalent Gene POU4F1 Promotes and Maintains Basal‐like Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11132042/
  77. May 2024
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC10651481/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11108982/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sirtuin3 ensures the metabolic plasticity of neurotransmission during glucose deprivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10660140/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXO22 is a potential therapeutic target for recurrent chondrosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089373/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of pancreatic cancer proliferation through TXNIP-mediated inhibition of the MAPK signaling pathway: TXNIP inhibits pancreatic cancer via the MAPK pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094629/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition : KLF5 mediates sensitivity to PARP in BRCA1-proficient PDAC
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    ncbi.nlm.nih.gov/pmc/articles/PMC11090855/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Influenza A virus NS1 effector domain is required for PA-X-mediated host shutoff in infected cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11092343/
  85. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes
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    sciencedirect.com/science/article/pii/S2211124721002011
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The phosphatidylinositol-5′ phosphatase synaptojanin1 limits integrin-mediated invasion of Staphylococcus aureus
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10986543/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondria inside acute myeloid leukemia cells hydrolyze ATP to resist chemotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042215/
  88. 52.53.155.43 52.53.155.43
    Beyond Glycolysis: Aldolase A is a Novel Effector in Reelin Mediated Dendritic Development
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    52.53.155.43/fbcd9c91bc2c853b235998551e36869172c1a2d9/2024.01.12.575269v1.full-html.html
  89. www.sciencedirect.com www.sciencedirect.com
    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
    2
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    sciencedirect.com/science/article/pii/S1934590924001292
  90. Apr 2024
  91. rupress.org rupress.org
    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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    rupress.org/jcb/article/223/6/e202308013/276631/WW-domains-form-a-folded-type-of-nuclear
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor‑suppressive effects of Smad‑ubiquitination regulator 2 in papillary thyroid carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11027108/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Strong Protection by 4-Hydroxyestrone against Erastin-Induced Ferroptotic Cell Death in Estrogen Receptor-Negative Human Breast Cancer Cells: Evidence for Protein Disulfide Isomerase as a Mechanistic Target for Protection
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    ncbi.nlm.nih.gov/pmc/articles/PMC11025120/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NS1-mediated enhancement of MVC transcription and replication promoted by KAT5/H4K12ac
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    ncbi.nlm.nih.gov/pmc/articles/PMC10949499/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10954759/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymidine nucleotide metabolism controls human telomere length
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