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Jul 2024
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HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages

1
1. scibot 04 Jul 2024
  
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  RRID:Addgene_10878
  
  DOI: 10.1038/s41467-024-49635-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11217462/
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Nuclear receptor E75/NR1D2 drives tumor malignant transformation by integrating Hippo and Notch pathways

1
1. scibot 04 Jul 2024
  
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  RRID:Addgene_10878
  
  DOI: 10.1101/2024.06.27.600913
  
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biorxiv.org/content/10.1101/2024.06.27.600913v1
Jun 2024
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miR-200-mediated inactivation of cancer-associated fibroblasts via targeting of NRP2-VEGFR signaling attenuates lung cancer invasion and metastasis

1
1. scibot 21 Jun 2024
  
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  plasmid_10878
  
  DOI: 10.1016/j.omtn.2024.102194
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11101731/
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Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma

1
1. scibot 15 Jun 2024
  
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  10878
  
  DOI: 10.1101/2024.05.27.596106
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11160645/
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Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

1
1. scibot 10 Jun 2024
  
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  Addgene_10878
  
  DOI: 10.1038/s44320-024-00032-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11148184/
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O-GlcNAcylation regulates the stability of transferrin receptor (TFRC) to control the ferroptosis in hepatocellular carcinoma cells

1
1. scibot 07 Jun 2024
  
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  pLKO.1-TRC vector
  
  DOI: 10.1016/j.redox.2024.103182
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11103954/
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Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening

1
1. scibot 07 Jun 2024
  
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  Addgene_10878
  
  DOI: 10.1101/2024.05.30.596755
  
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biorxiv.org/content/10.1101/2024.05.30.596755v1
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Mechanical activation of VE-cadherin stimulates AMPK to increase endothelial cell metabolism and vasodilation

1
1. scibot 06 Jun 2024
  
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  plasmid_10878
  
  DOI: 10.1101/2024.05.09.593171
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11118335/
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CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer

1
1. scibot 04 Jun 2024
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.canlet.2024.217006
  
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sciencedirect.com/science/article/pii/S0304383524004002
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Activation of Bivalent Gene POU4F1 Promotes and Maintains Basal‐like Breast Cancer

1
1. scibot 03 Jun 2024
  
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  10 878
  
  DOI: 10.1002/advs.202307660
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11132042/
May 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration

1
1. scibot 25 May 2024
  
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  plasmid_10878
  
  DOI: 10.1038/s41586-023-06701-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10651481/
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Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors

1
1. scibot 24 May 2024
  
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  plasmid_10878
  
  DOI: 10.1016/j.isci.2024.109860
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11108982/
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Sirtuin3 ensures the metabolic plasticity of neurotransmission during glucose deprivation

1
1. scibot 23 May 2024
  
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  10878; Addgene
  
  DOI: 10.1083/jcb.202305048
  
  Resource: RRID:Addgene_10878
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10660140/
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FBXO22 is a potential therapeutic target for recurrent chondrosarcoma

1
1. scibot 19 May 2024
  
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  10878
  
  DOI: 10.1016/j.jbo.2024.100605
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11089373/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Suppression of pancreatic cancer proliferation through TXNIP-mediated inhibition of the MAPK signaling pathway: TXNIP inhibits pancreatic cancer via the MAPK pathway

1
1. scibot 19 May 2024
  
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  10878
  
  DOI: 10.3724/abbs.2023286
  
  Resource: RRID:Addgene_10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11094629/
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Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition : KLF5 mediates sensitivity to PARP in BRCA1-proficient PDAC

1
1. scibot 19 May 2024
  
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  TRC cloning vector
  
  DOI: 10.3724/abbs.2023288
  
  Resource: RRID:Addgene_10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11090855/
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Influenza A virus NS1 effector domain is required for PA-X-mediated host shutoff in infected cells

1
1. scibot 17 May 2024
  
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  plasmid_10878
  
  DOI: 10.1128/jvi.01901-23
  
  Resource: RRID:Addgene_10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11092343/
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Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes

1
1. scibot 13 May 2024
  
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  addgene_10878
  
  DOI: 10.1016/j.celrep.2021.108887
  
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  Curator: @Naa003
  
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  RRID:Addgene_10878 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124721002011
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The phosphatidylinositol-5′ phosphatase synaptojanin1 limits integrin-mediated invasion of Staphylococcus aureus

1
1. scibot 12 May 2024
  
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  plasmid_10878
  
  DOI: 10.1128/spectrum.02006-23
  
  Resource: RRID:Addgene_10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10986543/
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Mitochondria inside acute myeloid leukemia cells hydrolyze ATP to resist chemotherapy

1
1. scibot 05 May 2024
  
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  10878
  
  DOI: 10.1101/2024.04.12.589110
  
  Resource: RRID:Addgene_10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11042215/
52.53.155.43 52.53.155.43

Beyond Glycolysis: Aldolase A is a Novel Effector in Reelin Mediated Dendritic Development

1
1. scibot 03 May 2024
  
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  RRID:Addgene_10878
  
  DOI: 10.1101/2024.01.12.575269
  
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52.53.155.43/fbcd9c91bc2c853b235998551e36869172c1a2d9/2024.01.12.575269v1.full-html.html
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Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease

2
1. scibot 01 May 2024
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.stem.2024.04.002
  
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2. scibot 01 May 2024
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.stem.2024.04.002
  
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sciencedirect.com/science/article/pii/S1934590924001292
Apr 2024
rupress.org rupress.org

WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import

1
1. scibot 25 Apr 2024
  
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  RRID:Addgene_10878
  
  DOI: 10.1083/jcb.202308013
  
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rupress.org/jcb/article/223/6/e202308013/276631/WW-domains-form-a-folded-type-of-nuclear
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Tumor‑suppressive effects of Smad‑ubiquitination regulator 2 in papillary thyroid carcinoma

1
1. scibot 23 Apr 2024
  
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  pLKO.1 lentiviral vector
  
  DOI: 10.3892/ol.2024.14396
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11027108/
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Strong Protection by 4-Hydroxyestrone against Erastin-Induced Ferroptotic Cell Death in Estrogen Receptor-Negative Human Breast Cancer Cells: Evidence for Protein Disulfide Isomerase as a Mechanistic Target for Protection

1
1. scibot 23 Apr 2024
  
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  10878
  
  DOI: 10.1021/acs.biochem.3c00261
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11025120/
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NS1-mediated enhancement of MVC transcription and replication promoted by KAT5/H4K12ac

1
1. scibot 15 Apr 2024
  
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  10878
  
  DOI: 10.1128/jvi.01695-23
  
  Resource: RRID:Addgene_10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10949499/
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Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer

1
1. scibot 15 Apr 2024
  
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  Addgene_10878
  
  DOI: 10.1038/s41467-024-46785-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10954759/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Thymidine nucleotide metabolism controls human telomere length

1
1. scibot 14 Apr 2024
  
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  10878
  
  DOI: 10.1038/s41588-023-01339-5
  
  Resource: RRID:Addgene_10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11000509/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RORα–GABP–TFAM axis alleviates myosteatosis with fatty atrophy through reinforcement of mitochondrial capacity

1
1. scibot 13 Apr 2024
  
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  pLKO‐TRC
  
  DOI: 10.1002/jcsm.13432
  
  Resource: RRID:Addgene_10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10995264/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HSPA9/mortalin inhibition disrupts erythroid maturation through a TP53-dependent mechanism in human CD34+ hematopoietic progenitor cells

1
1. scibot 13 Apr 2024
  
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  pLKO.1 vector
  
  DOI: 10.1016/j.cstres.2024.03.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10998001/
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Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer

1
1. scibot 01 Apr 2024
  
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  Addgene_10878
  
  DOI: 10.1126/sciadv.adk5386
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10971493/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DPY19L3 promotes vasculogenic mimicry by its C-mannosyltransferase activity

1
1. scibot 31 Mar 2024
  
  in Public
  
  pLKO.1-TRC cloning vector
  
  DOI: 10.32604/or.2023.030304
  
  Resource: RRID:Addgene_10878
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10972723/
www.nature.com www.nature.com

RBBP6 maintains glioblastoma stem cells through CPSF3-dependent alternative polyadenylation

2
1. scibot 28 Mar 2024
  
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  RRID:Addgene_10878
  
  DOI: 10.1038/s41421-024-00654-3
  
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2. scibot 22 Mar 2024
  
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  RRID:Addgene_10878
  
  DOI: 10.1038/s41421-024-00654-3
  
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nature.com/articles/s41421-024-00654-3
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression

1
1. scibot 20 Mar 2024
  
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  RRID:Addgene_10878
  
  DOI: 10.1158/2767-9764.CRC-23-0513
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10946310/
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A gut-derived hormone regulates cholesterol metabolism

1
1. scibot 19 Mar 2024
  
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  RRID: Addgene_10878
  
  DOI: 10.1016/j.cell.2024.02.024
  
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  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S0092867424002265
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FAM81A is a postsynaptic protein that regulates the condensation of postsynaptic proteins via liquid–liquid phase separation

1
1. scibot 17 Mar 2024
  
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  Plasmid_10878
  
  DOI: 10.1371/journal.pbio.3002006
  
  Resource: RRID:Addgene_10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10919877/
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Identifying regulators of aberrant stem cell and differentiation activity in colorectal cancer using a dual endogenous reporter system

1
1. scibot 16 Mar 2024
  
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  Addgene_10878
  
  DOI: 10.1038/s41467-024-46285-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10933491/
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The Impact of SLC2A8 RNA Interference on Glucose Uptake and the Transcriptome of Human Trophoblast Cells

1
1. scibot 16 Mar 2024
  
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  plasmid_10878
  
  DOI: 10.3390/cells13050391
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10930455/
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ALKBH1 promotes HIF-1α-mediated glycolysis by inhibiting N-glycosylation of LAMP2A

1
1. scibot 15 Mar 2024
  
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  plasmid_10878
  
  DOI: 10.1007/s00018-024-05152-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10933178/
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Inhibition of protein kinase C increases Prdm14 level to promote self-renewal of embryonic stem cells through reducing Suv39h-induced H3K9 methylation

1
1. scibot 08 Mar 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10909794/
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Palmitoylation of vacuole membrane protein 1 promotes small extracellular vesicle secretion via interaction with ALIX and influences intercellular communication

1
1. scibot 02 Mar 2024
  
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  10,878
  
  DOI: 10.1186/s12964-024-01529-6
  
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AF1q is a universal marker of neuroblastoma that sustains N-Myc expression and drives tumorigenesis

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  plasmid_10878
  
  DOI: 10.1038/s41388-024-02980-y
  
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nature.com/articles/s41388-024-02980-y
Feb 2024
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Epigenomic analyses identify FOXM1 as a key regulator of anti-tumor immune response in esophageal adenocarcinoma

1
1. scibot 29 Feb 2024
  
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  10878
  
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Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury

1
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  DOI: 10.1016/j.mcpro.2024.100723
  
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DDAH1 recruits peroxiredoxin 1 and sulfiredoxin 1 to preserve its activity and regulate intracellular redox homeostasis

1
1. scibot 29 Feb 2024
  
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  plasmid_10878
  
  DOI: 10.1016/j.redox.2024.103080
  
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Human RPF1 and ESF1 in Pre-rRNA Processing and the Assembly of Pre-Ribosomal Particles: A Functional Study

1
1. scibot 28 Feb 2024
  
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Human Betacoronavirus OC43 Interferes with the Integrated Stress Response Pathway in Infected Cells

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  plasmid_10878
  
  DOI: 10.3390/v16020212
  
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Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma

1
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  RRID:Addgene_10878
  
  DOI: 10.1158/1078-0432.CCR-23-2378
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10870201/
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Brucella targets the host ubiquitin-specific protease, Usp8, through the effector protein, TcpB, for facilitating infection of macrophages

1
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  plasmid_10878
  
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Surplus fatty acid synthesis increases oxidative stress in adipocytes and induces lipodystrophy

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ALKBH5 is a prognostic factor and promotes the angiogenesis of glioblastoma

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  DOI: 10.1038/s41598-024-51994-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10788339/
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Utilizing a dual endogenous reporter system to identify functional regulators of aberrant stem cell and differentiation activity in colorectal cancer

1
1. scibot 05 Feb 2024
  
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  DOI: 10.1101/2023.06.21.545895
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10827082/
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Modulations in the host cell proteome by the hantavirus nucleocapsid protein

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ncbi.nlm.nih.gov/pmc/articles/PMC10798635/
Jan 2024
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N-acetyltransferase 10 regulates alphavirus replication via N4-acetylcytidine (ac4C) modiﬁcation of the lymphocyte antigen six family member E (LY6E) mRNA

1
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  Addgene, #10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10805074/
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Growth-suppressor microRNAs mediate synaptic overgrowth and behavioral deficits in Fragile X mental retardation protein deficiency

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  DOI: 10.1016/j.isci.2023.108676
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10792201/
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A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation

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1. scibot 19 Jan 2024
  
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  RRID:Addgene_10
  
  DOI: 10.1016/j.canlet.2024.216635
  
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Intron retention as a productive mechanism in human MAPT: RNA species generated by retention of intron 3

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  DOI: 10.1016/j.ebiom.2023.104953
  
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sciencedirect.com/science/article/pii/S2352396423005194
Dec 2023
52.53.155.43 52.53.155.43

ATOH8 Expression is Regulated by BMP2 and Plays a Key Role in Human Endometrial Stromal Cell Decidualization

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  plasmid_10878
  
  DOI: 10.1210/endocr/bqad188
  
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52.53.155.43/f9b7e5fce08a981f088c308d1bff248479805472/bqad188-html.html
www.biorxiv.org www.biorxiv.org

A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation

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  RRID:Addgene_10878
  
  DOI: 10.1101/2023.11.15.567291
  
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biorxiv.org/content/10.1101/2023.11.15.567291v1
Nov 2023
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Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies

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  RRID:Addgene_10878
  
  DOI: 10.1016/j.ccell.2023.11.001
  
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sciencedirect.com/science/article/pii/S1535610823003665
Oct 2023
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Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness

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  plasmid_10878
  
  DOI: 10.1016/j.celrep.2023.113246
  
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sciencedirect.com/science/article/pii/S2211124723012585
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Atypical peripheral actin band formation via overactivation of RhoA and nonmuscle myosin II in mitofusin 2-deficient cells

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  RRID:Addgene_10878
  
  DOI: 10.7554/eLife.88828
  
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TET3 plays a critical role in white adipose development and diet-induced remodeling

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  RRID:Addgene_10878
  
  DOI: 10.1016/j.celrep.2023.113196
  
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sciencedirect.com/science/article/pii/S2211124723012081
Aug 2023
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MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy

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  RRID:Addgene_10878
  
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Pharmacological perturbation of the phase-separating protein SMNDC1

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  plasmid_10878
  
  DOI: 10.1038/s41467-023-40124-0
  
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nature.com/articles/s41467-023-40124-0
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Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development

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  RRID:Addgene_10878
  
  DOI: 10.1016/j.isci.2023.107368
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10407955/
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An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity

1
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  RRID:Addgene_10878
  
  DOI: 10.1101/2023.08.06.552174
  
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biorxiv.org/content/10.1101/2023.08.06.552174v1
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Differentiation block in acute myeloid leukemia regulated by intronic sequences of FTO

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  RRID:Addgene_10878
  
  DOI: 10.1016/j.isci.2023.107319
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10393733/
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Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion and proliferation

1
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  DOI: 10.1016/j.jbc.2023.105105
  
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sciencedirect.com/science/article/pii/S0021925823021336
Jun 2023
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Identification of XAF1 as an endogenous AKT inhibitor

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  RRID:Addgene_10878
  
  DOI: 10.1016/j.celrep.2023.112690
  
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Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting organotropic metastasis

1
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  RRID:Addgene_10878
  
  DOI: 10.1038/s41388-023-02742-2
  
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nature.com/articles/s41388-023-02742-2
May 2023
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CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis

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  DOI: 10.1016/j.ccell.2023.05.001
  
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ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells

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1. scibot 12 May 2023
  
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  RRID:Addgene_10878
  
  DOI: 10.7554/eLife.82450
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10171864/
Apr 2023
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Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2

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HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages

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Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation

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Mar 2023
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A micropattern-based assay to study contact inhibition of locomotion and entosis of adherent human and canine cells in vitro

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EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons

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Feb 2023
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Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise

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Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

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Jan 2023
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Kaposi’s sarcoma-associated herpesvirus (KSHV) utilizes the NDP52/CALCOCO2 selective autophagy receptor to disassemble processing bodies

1
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Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage

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Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation

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cell.com/cell/fulltext/S0092-8674(22)01517-3
Nov 2022
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AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis

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GPI-Anchored Ligand-BioID2-Tagging System Identifies Galectin-1 Mediating Zika Virus Entry

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Oct 2022
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Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity

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Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfments

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Sep 2022
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Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor

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Aug 2022
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SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression

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RBM47 is a Critical Regulator of Mouse Embryonic Stem Cell Differentiation

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  DOI: 10.1007/s12015-022-10441-w
  
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Negative autoregulation mitigates collateral RNase activity of repeat-targeting CRISPR-Cas13d in mammalian cells

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Multi-facet roles of RNA editing in promoting loss-of-function of PODXL in cancer

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Jun 2022
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Granger-causal inference of the lamellipodial actin regulator hierarchy by live cell imaging without perturbation

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Apr 2022
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CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair

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Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis

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Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma

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Mar 2022
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Paclitaxel Induce Apoptosis of Giant Cells Tumor of Bone via TP53INP1 Signaling

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Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function

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Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier

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  DOI: 10.1016/j.neuron.2022.02.017
  
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The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells

1
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  DOI: 10.7554/eLife.75827
  
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The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells

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  DOI: 10.3390/pharmaceutics14020329
  
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Recruitment of DNA to tumor-derived microvesicles

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  DOI: 10.1016/j.celrep.2022.110443
  
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Feb 2022
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ZEB1-regulated lnc-Nr2f1 promotes the migration and invasion of lung adenocarcinoma cells

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  DOI: 10.1016/j.canlet.2022.215601
  
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Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer

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sciencedirect.com/science/article/pii/S1535610822000058
Dec 2021
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RNA circles with minimized immunogenicity as potent PKR inhibitors

1
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  DOI: 10.1016/j.molcel.2021.11.019
  
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Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates

1
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  DOI: 10.7554/eLife.71982
  
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elifesciences.org/articles/71982
Nov 2021
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LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity

1
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  DOI: 10.1016/j.celrep.2021.110038
  
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The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma

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  DOI: 10.1371/journal.pgen.1009868
  
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MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal

1
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.celrep.2021.109949
  
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sciencedirect.com/science/article/pii/S2211124721014261
Aug 2021
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Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation

1
1. scibot 03 Aug 2021
  
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  plasmid_10878
  
  DOI: 10.3390/ijms22147753
  
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Jul 2021
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Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers

1
1. scibot 31 Jul 2021
  
  in Public
  
  Plasmid No. 10878
  
  DOI: 10.1016/j.cell.2021.07.005
  
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Molecular Tuning of the Axonal Mitochondrial Ca2+ Uniporter Ensures Metabolic Flexibility of Neurotransmission

1
1. scibot 31 Jul 2021
  
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  pPasmid #10878
  
  DOI: 10.1016/j.neuron.2019.11.020
  
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Widespread and Functional RNA Circularization in Localized Prostate Cancer

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:Addgene_10878
  
  DOI: 10.1016/j.cell.2019.01.025
  
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sciencedirect.com/science/article/pii/S0092867419300583
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Untitled document

1
1. scibot 31 Jul 2021
  
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  Plasmid_10878
  
  DOI: 10.1016/j.cmet.2018.12.020
  
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PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells

1
1. scibot 30 Jul 2021
  
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  Addgene Plasmid 10878
  
  DOI: 10.1016/j.celrep.2019.11.016
  
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sciencedirect.com/science/article/pii/S2211124719314871
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Untitled document

1
1. scibot 30 Jul 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.1111/os.12414
  
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onlinelibrary.wiley.com/doi/full/10.1111/os.12414
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p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas

1
1. scibot 29 Jul 2021
  
  in Public
  
  pLKO.1-puro
  
  DOI: 10.1016/j.celrep.2019.07.027
  
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sciencedirect.com/science/article/pii/S2211124719309246
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Untitled document

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.celrep.2018.11.035
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6342284/
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Untitled document

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.celrep.2018.11.035
  
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sciencedirect.com/science/article/pii/S2211124718317984
Jun 2021
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RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis

1
1. scibot 26 Jun 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.7554/eLife.63807
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8216719/
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HepaCAM controls astrocyte self-organization and coupling

1
1. scibot 25 Jun 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.neuron.2021.05.025
  
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sciencedirect.com/science/article/pii/S0896627321003780
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TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease

1
1. scibot 09 Jun 2021
  
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  Plasmid_10878
  
  DOI: 10.1016/j.cmet.2021.05.014
  
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sciencedirect.com/science/article/pii/S155041312100231X
May 2021
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The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding

1
1. scibot 26 May 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.celrep.2021.109184
  
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sciencedirect.com/science/article/pii/S2211124721005295
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Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress

1
1. scibot 09 May 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.stem.2020.05.007
  
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sciencedirect.com/science/article/pii/S1934590920302058
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Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability

1
1. scibot 07 May 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.molcel.2020.06.028
  
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sciencedirect.com/science/article/pii/S1097276520304305
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Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer

1
1. scibot 01 May 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.cmet.2021.01.018
  
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sciencedirect.com/science/article/pii/S1550413121000565
Apr 2021
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SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways

1
1. scibot 17 Apr 2021
  
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  Cat #10878
  
  DOI: 10.1016/j.ccell.2020.05.022
  
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sciencedirect.com/science/article/pii/S1535610820302725
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SEED-MEDIATED RNA INTERFERENCE OF ANDROGEN SIGNALING AND SURVIVAL NETWORKS INDUCES CELL DEATH IN PROSTATE CANCER CELLS

1
1. scibot 15 Apr 2021
  
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  Addgene_10878
  
  DOI: 10.1016/j.omtn.2021.03.002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8022159/
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Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma

1
1. scibot 11 Apr 2021
  
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  Addgene_10878
  
  DOI: 10.1016/j.stem.2021.02.003
  
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sciencedirect.com/science/article/pii/S1934590921000539
Mar 2021
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Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes

1
1. scibot 24 Mar 2021
  
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  addgene_10878
  
  DOI: 10.1016/j.celrep.2021.108887
  
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sciencedirect.com/science/article/pii/S2211124721002011
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A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV

1
1. scibot 18 Mar 2021
  
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  plasmid_10878
  
  DOI: 10.1016/j.celrep.2019.12.054
  
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sciencedirect.com/science/article/pii/S2211124719317115
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Ciliary neuropeptidergic signaling dynamically regulates excitatory synapses in postnatal neocortical pyramidal neurons

1
1. scibot 17 Mar 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.7554/eLife.65427
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7952091/
Feb 2021
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The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation

1
1. scibot 28 Feb 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.immuni.2020.12.010
  
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sciencedirect.com/science/article/pii/S1074761320305380
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The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages

1
1. scibot 24 Feb 2021
  
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  10878
  
  DOI: 10.1016/j.molcel.2020.12.040
  
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sciencedirect.com/science/article/pii/S1097276520309618
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The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma

1
1. scibot 24 Feb 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.molcel.2020.12.046
  
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sciencedirect.com/science/article/pii/S1097276520309886
Jan 2021
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Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells

1
1. scibot 29 Jan 2021
  
  in Public
  
  Plasmid_10878
  
  DOI: 10.1016/j.cell.2020.03.006
  
  Resource: RRID:Addgene_10878
  
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sciencedirect.com/science/article/pii/S0092867420302683
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Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC

1
1. scibot 27 Jan 2021
  
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  Addgene_10878
  
  DOI: 10.1016/j.celrep.2020.107568
  
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sciencedirect.com/science/article/pii/S2211124720305179
elifesciences.org elifesciences.org

Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division

1
1. scibot 05 Jan 2021
  
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  RRID:Addgene_10878
  
  DOI: 10.7554/eLife.63835
  
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elifesciences.org/articles/63835
Oct 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling

1
1. scibot 22 Oct 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.1172/jci.insight.141514
  
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pubmed.ncbi.nlm.nih.gov/32960816/
www.embopress.org www.embopress.org

Identification of a dynamic gene regulatory network required for pluripotency factor‐induced reprogramming of mouse fibroblasts and hepatocytes

1
1. scibot 13 Oct 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.15252/embj.2019102236
  
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embopress.org/doi/full/10.15252/embj.2019102236
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MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia

1
1. scibot 01 Oct 2020
  
  in Public
  
  pLKO.1 cloning vector
  
  DOI: 10.1016/j.stem.2020.09.004
  
  Resource: RRID:Addgene_10878
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S1934590920304501
Sep 2020
jcs.biologists.org jcs.biologists.org

Cofilin is required for polarization of tension in stress fiber networks during migration

1
1. scibot 23 Sep 2020
  
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  Addgene_10878
  
  DOI: 10.1242/jcs.243873
  
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jcs.biologists.org/content/133/13/jcs243873
www.mdpi.com www.mdpi.com

Molecular Signatures of JMJD10/MINA53 in Gastric Cancer

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:Addgene_10878
  
  DOI: 10.3390/cancers12051141
  
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mdpi.com/2072-6694/12/5/1141
onlinelibrary.wiley.com onlinelibrary.wiley.com

The matrix metalloproteinase 7 (MMP7) links Hsp90 chaperone with acquired drug resistance and tumor metastasis

1
1. scibot 16 Sep 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.1002/cnr2.1261
  
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onlinelibrary.wiley.com/doi/10.1002/cnr2.1261
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The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting

2
1. scibot 14 Sep 2020
  
  in Public
  
  addgene_10878
  
  DOI: 10.1016/j.celrep.2020.107944
  
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  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:Addgene_10878
2. scibot 03 Sep 2020
  
  in Public
  
  pLKO
  
  DOI: 10.1016/j.celrep.2020.107944
  
  Resource: RRID:Addgene_10878
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_10878
  
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sciencedirect.com/science/article/pii/S2211124720309256
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells

1
1. scibot 14 Sep 2020
  
  in Public
  
  plasmid_10878
  
  DOI: 10.7554/eLife.58504
  
  Resource: RRID:Addgene_10878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7473771/
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Hsp90 facilitates acquired drug resistance of tumor cells through cholesterol modulation however independent of tumor progression

1
1. scibot 14 Sep 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.bbamcr.2020.118728
  
  Resource: RRID:Addgene_10878
  
  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:Addgene_10878
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sciencedirect.com/science/article/pii/S0167488920300860
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations

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1. scibot 13 Sep 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.7554/eLife.51605
  
  Resource: RRID:Addgene_10878
  
  Curator: @evieth
  
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  RRIDCUR:Validated RRID:Addgene_10878
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ncbi.nlm.nih.gov/pmc/articles/PMC6961979/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Induction and Regulation of the Immunoproteasome Subunit β5i (PSMB8) in Laryngeal and Hypopharyngeal Carcinoma Cells

1
1. scibot 08 Sep 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.12659/MSM.923621
  
  Resource: RRID:Addgene_10878
  
  Curator: @evieth
  
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  RRID:Addgene_10878 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7366787/
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Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression

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1. scibot 06 Sep 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.devcel.2020.01.025
  
  Resource: RRID:Addgene_10878
  
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  RRID:Addgene_10878 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580720300575
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CNTF-STAT3-IL-6 Axis Mediates Neuroinflammatory Cascade across Schwann Cell-Neuron-Microglia

1
1. scibot 05 Sep 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.celrep.2020.107657
  
  Resource: RRID:Addgene_10878
  
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  RRIDCUR:Validated RRID:Addgene_10878
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sciencedirect.com/science/article/pii/S2211124720306100
elifesciences.org elifesciences.org

A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay

1
1. scibot 03 Sep 2020
  
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  RRID :Addgene10878
  
  DOI: 10.7554/eLife.54995
  
  Resource: RRID:Addgene_10878
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_10878
  
  Curator comments: pLKO.1 - TRC cloning vector
  
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  RRID:Addgene_10878
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elifesciences.org/articles/54995
elifesciences.org elifesciences.org

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137

1
1. scibot 03 Sep 2020
  
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  pLKO.1 TRC
  
  DOI: 10.7554/eLife.55806
  
  Resource: RRID:Addgene_10878
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_10878
  
  Curator comments: pLKO.1 - TRC cloning vector
  
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  RRID:Addgene_10878 RRIDCUR:Missing
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elifesciences.org/articles/55806
Jan 2020
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Targeting Wnt/EZH2/microRNA-708 signaling pathway inhibits neuroendocrine differentiation in prostate cancer

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.1038/s41420-019-0218-y
  
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  RRID:Addgene_10878 RRIDCUR:Validated
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nature.com/articles/s41420-019-0218-y
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Stimulation of Piezo1 by mechanical signals promotes bone anabolism

1
1. scibot 13 Jan 2020
  
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  Plasmid_10878
  
  DOI: 10.7554/eLife.49631
  
  Resource: RRID:Addgene_10878
  
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  SciCrunch record: Plasmid_10878
  
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  RRID:Addgene_10878 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6779475/
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Widespread and Functional RNA Circularization in Localized Prostate Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.cell.2019.01.025
  
  Resource: RRID:Addgene_10878
  
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  RRID:Addgene_10878 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867419300583
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Untitled document

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1. scibot 13 Jan 2020
  
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  Plasmid_10878
  
  DOI: 10.1016/j.cmet.2018.12.020
  
  Resource: RRID:Addgene_10878
  
  Curator: @ethanbadger
  
  SciCrunch record: Plasmid_10878
  
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  RRID:Addgene_10878 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413118307575
onlinelibrary.wiley.com onlinelibrary.wiley.com

Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.1111/os.12414
  
  Resource: RRID:Addgene_10878
  
  Curator: @evieth
  
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  RRID:Addgene_10878 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/full/10.1111/os.12414
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.stem.2019.01.011
  
  Resource: RRID:Addgene_10878
  
  Curator: @ethanbadger
  
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  RRID:Addgene_10878 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590919300116
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MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance

1
1. scibot 12 Jan 2020
  
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  RRID:Addgene_10878
  
  DOI: 10.1016/j.celrep.2019.02.023
  
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  Curator: @ethanbadger
  
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  RRID:Addgene_10878 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719301937

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