581 Matching Annotations
  1. Mar 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin reduces the clonal fitness of Dnmt3aR878H hematopoietic stem and progenitor cells by reversing their aberrant metabolic and epigenetic state
    1
    1. scibot 17 Mar 2024
      pCMV-VSVG

      DOI: 10.21203/rs.3.rs-3874821/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10889081/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient and scalable gene delivery method with easily generated cationic carbon dots
    1
    1. scibot 17 Mar 2024
      8454

      DOI: 10.1186/s12575-024-00232-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10921679/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized protocol for CRISPR knockout of human iPSC-derived macrophages
    1
    1. scibot 17 Mar 2024
      8454

      DOI: 10.1016/j.xpro.2024.102903

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    ncbi.nlm.nih.gov/pmc/articles/PMC10904194/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repeat DNA methylation is modulated by adherens junction signaling
    1
    1. scibot 17 Mar 2024
      8454

      DOI: 10.1038/s42003-024-05990-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920906/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The neuronal transcription factor MEIS2 is a calpain2 protease target
    1
    1. scibot 17 Mar 2024
      Addgene_8454

      DOI: 10.1242/jcs.261482

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    ncbi.nlm.nih.gov/pmc/articles/PMC10941658/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Multiple Alternative Mitogenic Signaling Pathways Accompanies the Emergence of Drug-Tolerant Cancer Cells
    1
    1. scibot 16 Mar 2024
      Addgene_8454

      DOI: 10.3390/cancers16051001

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    ncbi.nlm.nih.gov/pmc/articles/PMC10930612/
  8. www.biorxiv.org www.biorxiv.org
    Combinatorial in vivo genome editing identifies widespread epistasis during lung tumorigenesis
    1
    1. scibot 15 Mar 2024
      Addgene_8454

      DOI: 10.1101/2024.03.07.583981

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    biorxiv.org/content/10.1101/2024.03.07.583981v1
  9. www.sciencedirect.com www.sciencedirect.com
    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
    1
    1. scibot 08 Mar 2024
      Plasmid #8454

      DOI: 10.1016/j.molcel.2024.02.010

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    sciencedirect.com/science/article/pii/S1097276524001291
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The helicase domain of human Dicer prevents RNAi-independent activation of antiviral and inflammatory pathways
    1
    1. scibot 08 Mar 2024
      Addgene_8454

      DOI: 10.1038/s44318-024-00035-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10907635/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FH variant pathogenicity promotes purine salvage pathway dependence in kidney cancer
    1
    1. scibot 06 Mar 2024
      RRID:Addgene_8454

      DOI: 10.1158/2159-8290.CD-22-0874

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527600/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene editing-based targeted integration for correction of Wiskott-Aldrich syndrome
    1
    1. scibot 02 Mar 2024
      pCMV-VSV-G

      DOI: 10.1016/j.omtm.2024.101208

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897892/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Programmable RNA writing with trans-splicing
    1
    1. scibot 02 Mar 2024
      Addgene_8454

      DOI: 10.1101/2024.01.31.578223

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    ncbi.nlm.nih.gov/pmc/articles/PMC10862893/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination
    1
    1. scibot 01 Mar 2024
      pCMV-VSVG

      DOI: 10.1038/s44318-023-00018-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897158/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis
    1
    1. scibot 01 Mar 2024
      8454

      DOI: 10.7554/eLife.86168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10901513/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integration of transcription regulation and functional genomic data reveals lncRNA SNHG6’s role in hematopoietic differentiation and leukemia
    1
    1. scibot 01 Mar 2024
      plasmid_8454

      DOI: 10.1186/s12929-024-01015-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10900714/
  17. Feb 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer
    1
    1. scibot 29 Feb 2024
      8454

      DOI: 10.1128/jvi.01726-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10878100/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis
    1
    1. scibot 29 Feb 2024
      8454

      DOI: 10.1128/jvi.01909-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10878271/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POZ/BTB and AT hook containing zinc finger 1 (PATZ1) suppresses differentiation and regulates metabolism in human embryonic stem cells
    1
    1. scibot 29 Feb 2024
      VSVG

      DOI: 10.7150/ijbs.83927

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    ncbi.nlm.nih.gov/pmc/articles/PMC10878140/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties
    1
    1. scibot 29 Feb 2024
      pCMV-VSV-G

      DOI: 10.1038/s41540-024-00344-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10881528/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Open-source milligram-scale, four channel, automated protein purification system
    1
    1. scibot 29 Feb 2024
      8454

      DOI: 10.1371/journal.pone.0297879

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    ncbi.nlm.nih.gov/pmc/articles/PMC10889886/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma
    1
    1. scibot 29 Feb 2024
      plasmid_8454

      DOI: 10.1038/s41467-024-46048-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879147/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative MRI Evaluation of Ferritin Overexpression in Non-Small-Cell Lung Cancer
    1
    1. scibot 28 Feb 2024
      pCMV-VSV-G

      DOI: 10.3390/ijms25042398

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    ncbi.nlm.nih.gov/pmc/articles/PMC10889593/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth
    1
    1. scibot 28 Feb 2024
      pCMV-VSV-G

      DOI: 10.1038/s41388-023-02933-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10890933/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia
    1
    1. scibot 28 Feb 2024
      RRID:Addgene_8454

      DOI: 10.1126/sciadv.adi3771

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    ncbi.nlm.nih.gov/pmc/articles/PMC10881058/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IMPDH2 filaments protect from neurodegeneration in AMPD2 deficiency
    1
    1. scibot 16 Feb 2024
      8454

      DOI: 10.1101/2024.01.20.576443

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    ncbi.nlm.nih.gov/pmc/articles/PMC10849482/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Proximity Labeling Reveals an Expanded Interactome for the Matrisome Protein TIMP2
    1
    1. scibot 16 Feb 2024
      plasmid_8454

      DOI: 10.21203/rs.3.rs-3857263/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10836090/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma
    1
    1. scibot 15 Feb 2024
      8454

      DOI: 10.1038/s41420-024-01842-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10861597/
  30. www.sciencedirect.com www.sciencedirect.com
    Protocol for organelle-specific cysteine capture and quantification of cysteine oxidation state
    1
    1. scibot 15 Feb 2024
      Addgene_8454

      DOI: 10.1016/j.xpro.2024.102865

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    sciencedirect.com/science/article/pii/S2666166724000303
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription-Coupled Repair of DNA Interstrand Crosslinks by UVSSA
    1
    1. scibot 13 Feb 2024
      8454

      DOI: 10.1101/2023.05.10.538304

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    ncbi.nlm.nih.gov/pmc/articles/PMC10197625/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of dabrafenib-induced drug insensitivity via cellular barcoding and collateral sensitivity to second-line therapeutics
    1
    1. scibot 13 Feb 2024
      8454

      DOI: 10.1038/s41598-023-50443-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10762103/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP54 is a potential therapeutic target in castration-resistant prostate cancer
    1
    1. scibot 13 Feb 2024
      8454

      DOI: 10.1186/s12894-024-01418-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10845770/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-step docking by WIPI2, ATG16L1, and ATG3 delivers LC3 to the phagophore
    1
    1. scibot 13 Feb 2024
      8454

      DOI: 10.1126/sciadv.adj8027

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    ncbi.nlm.nih.gov/pmc/articles/PMC10851258/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection
    1
    1. scibot 08 Feb 2024
      8454

      DOI: 10.1038/s41467-023-44175-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10761986/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitofusin 1 silencing decreases the senescent associated secretory phenotype, promotes immune cell recruitment and delays melanoma tumor growth after chemotherapy
    1
    1. scibot 08 Feb 2024
      8454

      DOI: 10.1038/s41598-024-51427-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10776601/
  37. www.sciencedirect.com www.sciencedirect.com
    Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition
    1
    1. scibot 08 Feb 2024
      RRID:Addgene_8454

      DOI: 10.1016/j.celrep.2024.113749

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    sciencedirect.com/science/article/pii/S2211124724000779
  38. link.springer.com link.springer.com
    Effect of Octamer-Binding Transcription Factor 4 Overexpression on the Neural Induction of Human Dental Pulp Stem Cells
    1
    1. scibot 07 Feb 2024
      RRID:Addgene_8454

      DOI: 10.1007/s12015-024-10678-7

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    link.springer.com/article/10.1007/s12015-024-10678-7
  39. www.sciencedirect.com www.sciencedirect.com
    One-pot DTECT enables rapid and efficient capture of genetic signatures for precision genome editing and clinical diagnostics
    1
    1. scibot 07 Feb 2024
      RRID:Addgene_8454

      DOI: 10.1016/j.crmeth.2024.100698

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    sciencedirect.com/science/article/pii/S2667237524000043
  40. www.sciencedirect.com www.sciencedirect.com
    Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors
    1
    1. scibot 06 Feb 2024
      Addgene_8454

      DOI: 10.1016/j.devcel.2023.12.010

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    sciencedirect.com/science/article/pii/S1534580723006901
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micronucleus is not a potent inducer of the cGAS/STING pathway
    1
    1. scibot 05 Feb 2024
      8454

      DOI: 10.26508/lsa.202302424

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    ncbi.nlm.nih.gov/pmc/articles/PMC10837050/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germinal Center Cytokines Driven Epigenetic Control of Epstein-Barr Virus Latency Gene Expression
    1
    1. scibot 05 Feb 2024
      plasmid_8454

      DOI: 10.1101/2024.01.02.573986

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802360/
  43. www.sciencedirect.com www.sciencedirect.com
    PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome
    1
    1. scibot 02 Feb 2024
      RRID: Addgene_8454

      DOI: 10.1016/j.cell.2024.01.009

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    sciencedirect.com/science/article/pii/S0092867424000114
  44. www.sciencedirect.com www.sciencedirect.com
    CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs
    1
    1. scibot 02 Feb 2024
      plasmid_8454

      DOI: 10.1016/j.molcel.2024.01.006

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    sciencedirect.com/science/article/pii/S1097276524000078
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3
    1
    1. scibot 01 Feb 2024
      pCMV-VSV-G

      DOI: 10.1186/s12964-024-01484-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10826106/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis
    1
    1. scibot 01 Feb 2024
      8454

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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Charting Single Cell Lineage Dynamics and Mutation Networks via Homing CRISPR
    1
    1. scibot 01 Feb 2024
      8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802354/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene engineered exosome reverses T cell exhaustion in cancer immunotherapy
    1
    1. scibot 01 Feb 2024
      plasmid_8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10825617/
  49. Jan 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis
    1
    1. scibot 30 Jan 2024
      AddGene 8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10801937/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxynorketamine, but not ketamine, acts via α7 nicotinic acetylcholine receptor to control presynaptic function and gene expression
    1
    1. scibot 30 Jan 2024
      #8454, Addgene

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    ncbi.nlm.nih.gov/pmc/articles/PMC10803733/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Involvement of Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Design
    1
    1. scibot 30 Jan 2024
      8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10813316/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nonsynonymous Mutations in Intellectual Disability and Autism Spectrum Disorder Gene PTCHD1 Disrupt N-Glycosylation and Reduce Protein Stability
    1
    1. scibot 29 Jan 2024
      #8454; Addgene

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    ncbi.nlm.nih.gov/pmc/articles/PMC10814814/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability
    1
    1. scibot 29 Jan 2024
      Plasmid_8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802603/
  55. www.sciencedirect.com www.sciencedirect.com
    Massively parallel disruption of enhancers active in human neural stem cells
    2
    1. scibot 25 Jan 2024
      Plasmid_8454

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    sciencedirect.com/science/article/pii/S2211124724000214
  56. www.sciencedirect.com www.sciencedirect.com
    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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      RRID: Addgene_8454

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    sciencedirect.com/science/article/pii/S2666379123006171
  57. www.science.org www.science.org
    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    science.org/doi/10.1126/sciadv.ade1282
  58. www.sciencedirect.com www.sciencedirect.com
    Nuclear phosphoproteome reveals Prolyl Isomerase PIN1 as a modulator of oncogene-induced senescence.
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  59. dx.doi.org dx.doi.org
    Kaposi's sarcoma herpesvirus exploits the DNA damage response to circularize its genome
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    dx.doi.org/10.1093/nar/gkad1224
  60. Dec 2023
  61. www.sciencedirect.com www.sciencedirect.com
    An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma
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    sciencedirect.com/science/article/pii/S2211124723015693
  62. www.sciencedirect.com www.sciencedirect.com
    Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
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  63. www.sciencedirect.com www.sciencedirect.com
    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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    sciencedirect.com/science/article/pii/S2589004223026731
  64. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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      Addgene Cat: 8454

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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-genome analysis reveals heterogeneous association of the Herpes Simplex Virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts
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  66. www.sciencedirect.com www.sciencedirect.com
    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
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    sciencedirect.com/science/article/pii/S2451945623004257
  67. 52.53.155.43 52.53.155.43
    978-1-0716-3593-3-html.html
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    52.53.155.43/13e95334a348a589bd777c46a75603c23c56efd2/978-1-0716-3593-3-html.html
  68. link.springer.com link.springer.com
    Rational optimization of a transcription factor activation domain inhibitor
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      DOI: 10.1038/s41594-023-01159-5

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  69. Nov 2023
  70. www.sciencedirect.com www.sciencedirect.com
    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
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    A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment
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    sciencedirect.com/science/article/pii/S2666379123004809
  72. www.sciencedirect.com www.sciencedirect.com
    Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
    3
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      Addgene #8454

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    sciencedirect.com/science/article/pii/S2211124723014900
  73. www.sciencedirect.com www.sciencedirect.com
    Aryl Hydrocarbon Receptor is a Tumor Promoter in MYCN-Amplified Neuroblastoma Cells Through Suppression of Differentiation
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      Plasmid_8454

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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12
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    1. scibot 15 Nov 2023
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  75. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
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      DOI: 10.1016/j.immuni.2023.10.004

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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal activation of Gαq EGL-30/GNAQ late in life rejuvenates cognition across species
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  77. www.sciencedirect.com www.sciencedirect.com
    Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells
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  78. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 screens unravel miR-3689a-3p regulating sorafenib resistance in hepatocellular carcinoma via suppressing CCS/SOD1-dependent mitochondrial oxidative stress
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  79. Oct 2023
  80. link.springer.com link.springer.com
    A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens
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      DOI: 10.1186/s12864-023-09754-y

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  81. www.sciencedirect.com www.sciencedirect.com
    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
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  82. www.biorxiv.org www.biorxiv.org
    Dicer deficiency in microglia leads to accelerated demyelination and failed remyelination
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    biorxiv.org/content/10.1101/2023.10.17.562812v1
  83. www.biorxiv.org www.biorxiv.org
    Genome-wide CRISPR/Cas9 screen identifies MAT2A as a critical host factor for BK Polyomavirus
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      DOI: 10.1101/2023.10.20.563362

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  84. www.sciencedirect.com www.sciencedirect.com
    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
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      DOI: 10.1016/j.celrep.2023.113198

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  85. www.mdpi.com www.mdpi.com
    Activation of Chaperone-Mediated Autophagy Inhibits the Aryl Hydrocarbon Receptor Function by Degrading This Receptor in Human Lung Epithelial Carcinoma A549 Cells
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  86. www.sciencedirect.com www.sciencedirect.com
    Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells
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  87. www.sciencedirect.com www.sciencedirect.com
    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atypical peripheral actin band formation via overactivation of RhoA and nonmuscle myosin II in mitofusin 2-deficient cells
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      DOI: 10.7554/eLife.88828

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    ncbi.nlm.nih.gov/pmc/articles/PMC10550287/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pyruvate Kinase Activity Regulates Cystine Starvation Induced Ferroptosis through Malic Enzyme 1 in Pancreatic Cancer Cells
    1
    1. scibot 05 Oct 2023
      plasmid_8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10516027/
  90. Sep 2023
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing
    1
    1. scibot 23 Sep 2023
      RRID:Addgene_8454

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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The IFT81‐IFT74 complex acts as an unconventional RabL2 GTPase‐activating protein during intraflagellar transport
    1
    1. scibot 20 Sep 2023
      plasmid_8454

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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    microRNAs slow translating ribosomes to prevent protein misfolding in eukaryotes
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  94. dx.doi.org dx.doi.org
    Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma
    1
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      RRID:Addgene_8454

      DOI: 10.1158/0008-5472.CAN-22-3114

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    dx.doi.org/10.1158/0008-5472.CAN-22-3114
  95. link.springer.com link.springer.com
    Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization
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      DOI: 10.1007/s13402-023-00867-w

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  96. www.sciencedirect.com www.sciencedirect.com
    Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection
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      Addgene plasmid #8454

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    sciencedirect.com/science/article/pii/S1534580723004094
  97. Aug 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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      RRID:Addgene_8454

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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens
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    ncbi.nlm.nih.gov/pmc/articles/PMC9882262/
  100. www.sciencedirect.com www.sciencedirect.com
    MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy
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  101. www.science.org www.science.org
    Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12
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  102. www.nature.com www.nature.com
    Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells
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      DOI: 10.1038/s41467-023-40222-z

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    nature.com/articles/s41467-023-40222-z
  103. www.nature.com www.nature.com
    An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver
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  104. www.sciencedirect.com www.sciencedirect.com
    IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function
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  105. www.embopress.org www.embopress.org
    Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors
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    1. scibot 23 Aug 2023
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  106. 52.53.155.43 52.53.155.43
    SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine
    2
    1. scibot 17 Aug 2023
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    52.53.155.43/746dceaaaecd8ad8008d9df523b985f7a77f181a/PIIS2211124723009518-html.html
  107. www.biorxiv.org www.biorxiv.org
    The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC reprogramming
    3
    1. scibot 12 Aug 2023
      plasmid #8454

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    biorxiv.org/content/10.1101/2023.07.31.551297v3
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of store-operated Ca2+ entry by IP3 receptors independent of their ability to release Ca2+
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    1. scibot 09 Aug 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10406432/
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response Pathway
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      RRID:Addgene_8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10391328/
  110. Jul 2023
  111. www.embopress.org www.embopress.org
    Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells
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      RRID:Addgene_8454

      DOI: 10.15252/embr.202256279

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  112. 52.53.155.43 52.53.155.43
    Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal
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      8454

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  113. www.biorxiv.org www.biorxiv.org
    Neuronal Activation of the Gαq Protein EGL-30/GNAQ Late in Life Rejuvenates Cognition Across Species
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  114. 52.53.155.43 52.53.155.43
    can-22-3173-html.html
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  115. Jun 2023
  116. 52.53.155.43 52.53.155.43
    can-22-3173-html.html
    1
    1. scibot 30 Jun 2023
      RRID:Addgene_8454

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  117. www.sciencedirect.com www.sciencedirect.com
    LC3B is lipidated to large lipid droplets during prolonged starvation for noncanonical autophagy
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
  119. www.sciencedirect.com www.sciencedirect.com
    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coupled protein quality control during nonsense-mediated mRNA decay
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      Addgene_8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10234110/
  121. May 2023
  122. www.sciencedirect.com www.sciencedirect.com
    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
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      RRID:Addgene_8454

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    sciencedirect.com/science/article/pii/S2211124723005478
  123. www.sciencedirect.com www.sciencedirect.com
    ATR protects centromere identity by promoting DAXX association with PML nuclear bodies
    1
    1. scibot 11 May 2023
      Plasmid_8454

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    sciencedirect.com/science/article/pii/S2211124723005065
  124. www.sciencedirect.com www.sciencedirect.com
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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      RRID: Addgene 8454

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    sciencedirect.com/science/article/pii/S2211124723004953
  125. journals.asm.org journals.asm.org
    Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
    1
    1. scibot 05 May 2023
      RRID:Addgene_8454

      DOI: 10.1128/mbio.01055-22

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    journals.asm.org/doi/10.1128/mbio.01055-22
  126. Apr 2023
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
    1
    1. scibot 27 Apr 2023
      plasmid_8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10115456/
  128. www.sciencedirect.com www.sciencedirect.com
    ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion
    1
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intronic Cis-Element DR8 in hTERT Is Bound by Splicing Factor SF3B4 and Regulates hTERT Splicing in Non-Small Cell Lung Cancer
    1
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      RRID:Addgene_8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC9532359/
  130. elifesciences.org elifesciences.org
    NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation
    1
    1. scibot 12 Apr 2023
      RRID:Addgene_8454

      DOI: 10.7554/eLife.81569

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  131. www.sciencedirect.com www.sciencedirect.com
    Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation
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      RRID:Addgene_8454

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    sciencedirect.com/science/article/pii/S1934590923000760
  132. www.sciencedirect.com www.sciencedirect.com
    The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage
    1
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      Plasmid_8454

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  133. Mar 2023
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LIN28 and histone H3K4 methylase induce TLR4 to generate tumor-initiating stem-like cells
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      DOI: 10.1016/j.isci.2023.106254

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  135. www.sciencedirect.com www.sciencedirect.com
    A central chaperone-like role for 14-3-3 proteins in human cells
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      Addgene 8454

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  136. www.sciencedirect.com www.sciencedirect.com
    Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment
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      RRID:Addgene_8454

      DOI: 10.1016/j.ccell.2023.02.005

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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease
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  138. www.sciencedirect.com www.sciencedirect.com
    IFNγ is a central node of cancer immune equilibrium
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CAR-T Cells with Phytohemagglutinin (PHA) Provide Anti-Cancer Capacity with Better Proliferation, Rejuvenated Effector Memory, and Reduced Exhausted T Cell Frequencies
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  140. Feb 2023
  141. www.sciencedirect.com www.sciencedirect.com
    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
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  142. link.springer.com link.springer.com
    Baculovirus displaying SARS-CoV-2 spike RBD promotes neutralizing antibody production in a mouse model
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  143. www.sciencedirect.com www.sciencedirect.com
    Monitoring cell fate in 3D organotypic human squamous epithelial cultures
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combinatorial Treatment with Poly(ADP-ribose) Polymerase-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth Through Fos-Driven Changes in Gene Expression
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer
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  146. elifesciences.org elifesciences.org
    T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation
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  147. Jan 2023
  148. www.sciencedirect.com www.sciencedirect.com
    Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation
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  149. www.science.org www.science.org
    Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases
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    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
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    Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
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    RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer
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  153. www.biorxiv.org www.biorxiv.org
    Area postrema neurons mediate interleukin-6 function in cancer-associated cachexia
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    Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway
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  155. 52.53.155.43 52.53.155.43
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  156. www.pnas.org www.pnas.org
    Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs
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    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of β2 microglobulin, the product of B2M gene, as a Host Factor for Vaccinia Virus Infection by Genome-Wide CRISPR genetic screens
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  159. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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  161. www.sciencedirect.com www.sciencedirect.com
    Functional partitioning of transcriptional regulators by patterned charge blocks
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  162. www.sciencedirect.com www.sciencedirect.com
    PAX8 modulates the tumor microenvironment of high grade serous ovarian cancer through changes in the secretome
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  163. Dec 2022
  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
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  167. academic.oup.com academic.oup.com
    Heterogeneous nuclear ribonucleoprotein K is overexpressed in acute myeloid leukemia and causes myeloproliferation in mice via altered Runx1 splicing
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      DOI: 10.1093/narcan/zcac039

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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness
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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Sall2 transcription factor promotes cell migration regulating focal adhesion turnover and integrin β1 expression
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  171. Nov 2022
  172. www.mdpi.com www.mdpi.com
    Bcl-2 Family Members Bcl-xL and Bax Cooperatively Contribute to Bortezomib Resistance in Mantle Cell Lymphoma
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  173. www.sciencedirect.com www.sciencedirect.com
    Autophagy promotes cell survival by maintaining NAD levels
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  174. onlinelibrary.wiley.com onlinelibrary.wiley.com
    HIV-induced bystander cell death in astrocytes requires cell-to-cell viral transmission
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  175. www.sciencedirect.com www.sciencedirect.com
    Genome-scale CRISPR screening in a single mouse liver
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    Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function
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    NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma
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  178. www.sciencedirect.com www.sciencedirect.com
    Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma
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  179. www.sciencedirect.com www.sciencedirect.com
    Protocol to image and quantify nucleocytoplasmic transport in cultured cells using fluorescent in situ hybridization and a dual reporter system
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  180. Oct 2022
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    Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein
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  182. www.sciencedirect.com www.sciencedirect.com
    Angiotensin II receptor type 1 blockade regulates Klotho expression to induce TSC2-deficient cell death
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  183. www.sciencedirect.com www.sciencedirect.com
    In vitro neurons learn and exhibit sentience when embodied in a simulated game-world
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    sciencedirect.com/science/article/pii/S0896627322008066
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
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    1. scibot 02 Oct 2022
      RRID:Addgene_8454

      DOI: 10.1016/j.isci.2022.105050

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    ncbi.nlm.nih.gov/pmc/articles/PMC9519511/
  185. Sep 2022
  186. www.sciencedirect.com www.sciencedirect.com
    The lncRNA ALPHA specifically targets chikungunya virus to control infection
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    1. scibot 27 Sep 2022
      RRID:Addgene_8454

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    sciencedirect.com/science/article/pii/S1097276522008504
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study
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    1. scibot 22 Sep 2022
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      DOI: 10.4274/jtgga.galenos.2022.2022-1-14

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    ncbi.nlm.nih.gov/pmc/articles/PMC9450920/
  188. www.sciencedirect.com www.sciencedirect.com
    Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization
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      RRID:Addgene_8454

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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development and Characterization of a Luciferase Labeled, Syngeneic Murine Model of Ovarian Cancer
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    1. scibot 14 Sep 2022
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      DOI: 10.3390/cancers14174219

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    ncbi.nlm.nih.gov/pmc/articles/PMC9454869/
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
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      RRID:Addgene_8454

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  191. Aug 2022
  192. www.sciencedirect.com www.sciencedirect.com
    RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs
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      Plasmid #8454

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  193. 52.53.155.43 52.53.155.43
    cd-21-1671-html.html
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  194. 52.53.155.43 52.53.155.43
    mcr-21-0058-html.html
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  195. www.sciencedirect.com www.sciencedirect.com
    Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth
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  197. www.sciencedirect.com www.sciencedirect.com
    Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression
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    1. scibot 23 Aug 2022
      plasmid_8454

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  198. www.sciencedirect.com www.sciencedirect.com
    Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
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    sciencedirect.com/science/article/pii/S221112472201018X
  199. www.sciencedirect.com www.sciencedirect.com
    Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases
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  200. www.sciencedirect.com www.sciencedirect.com
    Saturation of the mitochondrial NADH shuttles drives aerobic glycolysis in proliferating cells
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  201. www.sciencedirect.com www.sciencedirect.com
    Identification of a drug-response gene in multiple myeloma through longitudinal single-cell transcriptome sequencing
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      RRID:Addgene_8454

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    sciencedirect.com/science/article/pii/S2589004222010537
  202. Jul 2022
  203. 52.53.155.43 52.53.155.43
    cir-22-0088-html.html
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  204. www.sciencedirect.com www.sciencedirect.com
    Direct reprogramming of adult adipose-derived regenerative cells toward cardiomyocytes using six transcriptional factors
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      RRID:Addgene_8454

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    sciencedirect.com/science/article/pii/S2589004222009233
  205. Jun 2022
  206. 52.53.155.43 52.53.155.43
    mcr-22-0111-html.html
    2
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  207. www.embopress.org www.embopress.org
    Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells
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      RRID:Addgene_8454

      DOI: 10.15252/embr.202154133

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  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A New Functional Screening Platform Identifies Colistin Sulfate as an Enhancer of Natural Killer Cell Cytotoxicity
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      DOI: 10.3390/cancers14122832

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  209. www.sciencedirect.com www.sciencedirect.com
    Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling
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      AddgeneCat# 8454

      DOI: 10.1016/j.chembiol.2022.05.012

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    sciencedirect.com/science/article/pii/S2451945622002045
  210. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
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      DOI: 10.1186/s13024-022-00550-y

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    molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-022-00550-y
  211. www.sciencedirect.com www.sciencedirect.com
    Analysis of estrogen-regulated enhancer RNAs identifies a functional motif required for enhancer assembly and gene expression
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    1. scibot 15 Jun 2022
      AddgeneCat. No.: 8454

      DOI: 10.1016/j.celrep.2022.110944

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    sciencedirect.com/science/article/pii/S2211124722007264
  212. May 2022
  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9
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    1. scibot 24 May 2022
      RRID:Addgene_8454

      DOI: 10.7554/eLife.75594

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    ncbi.nlm.nih.gov/pmc/articles/PMC9122501/
  214. www.sciencedirect.com www.sciencedirect.com
    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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    1. scibot 12 May 2022
      plasmid_8454

      DOI: 10.1016/j.cell.2022.04.019

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