1,070 Matching Annotations
  1. Jun 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TIMP1 secretion induced by Toxoplasma effector GRA24 via p38 MAPK signaling promotes non-disruptive parasite translocation across polarized brain endothelial monolayers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12108053/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Snora54 negatively regulates self-renewal of intestinal stem cells and gut regeneration via suppression of Notch2 signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12101510/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial calcium signaling regulates branched-chain amino acid catabolism in fibrolamellar carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12118637/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune cell infiltration into brain tumor microenvironment is mediated by Rab27-regulated vascular wall integrity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12101492/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RABEP1 amplifies front signaling in neutrophil migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12132377/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bat organoids reveal antiviral responses at epithelial surfaces
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    pmc.ncbi.nlm.nih.gov/articles/PMC12133567/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage
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    pmc.ncbi.nlm.nih.gov/articles/PMC12162470/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor-derived erythropoietin acts as an immunosuppressive switch in cancer immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12110762/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetically encoded fluorescent reporter for polyamines
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    pmc.ncbi.nlm.nih.gov/articles/PMC12117157/
  11. link.springer.com link.springer.com
    Application of CRISPR-Based Epigenome Editing Tools for Engineering Programmable Embryo Models
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    link.springer.com/protocol/10.1007/7651_2025_637
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ONECUT2 reprograms neuroendocrine fate and is an actionable therapeutic target in small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12153148/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of LAPTM4A inhibits M2 polarization of tumor-associated macrophages in glioblastoma, promoting immune activation and enhancing anti-PD1 therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12159176/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heat shock induces alternative polyadenylation through dynamic DNA methylation and chromatin looping
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    pmc.ncbi.nlm.nih.gov/articles/PMC12162027/
  15. www.mdpi.com www.mdpi.com
    SARS-Cov-2 Replication in a Blood–Brain Barrier Model Established with Human Brain Microvascular Endothelial Cells Induces Permeability and Disables ACE2-Dependent Regulation of Bradykinin B1 Receptor
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    mdpi.com/1422-0067/26/12/5540
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell‐Type‐Specific Autophagy in Human Leukocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12159969/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting MYOF suppresses pancreatic ductal adenocarcinoma progression by inhibiting ILF3-LCN2 signaling through disrupting OTUB1-mediated deubiquitination of ILF3
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    pmc.ncbi.nlm.nih.gov/articles/PMC12145718/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR antiviral inhibits neurotrophic JC polyomavirus in 2D and 3D culture models through dual-gRNA excision by SaCas9
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    pmc.ncbi.nlm.nih.gov/articles/PMC12159223/
  19. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/222b3bee495041e065bdee761a6ce36008a4c9e7/PDF-html.html
  20. 52.53.155.43 52.53.155.43
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    52.53.155.43/39661a60067369c81e4f8c30deffb29c14ec6c80/PDF-html.html
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RalGAP complexes control secretion and primary cilia in pancreatic disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12149561/
  22. 52.53.155.43 52.53.155.43
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    52.53.155.43/6d05284590fa38103d7fbc1633c815ab1c347fcd/PDF-html.html
  23. elifesciences.org elifesciences.org
    A Commander-independent function of COMMD3 in endosomal trafficking
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    elifesciences.org/reviewed-preprints/105264
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphatase activity is dispensable for PRL-3-mediated oncogenesis and tumor progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12132575/
  25. www.sciencedirect.com www.sciencedirect.com
    Cholesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S2211124725005637
  26. May 2025
  27. www.sciencedirect.com www.sciencedirect.com
    Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids
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    sciencedirect.com/science/article/pii/S153458072500262X
  28. www.sciencedirect.com www.sciencedirect.com
    Two waves of adipogenesis in developing avian skin and dermal plasticity
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    sciencedirect.com/science/article/pii/S0012160625001423
  29. www.sciencedirect.com www.sciencedirect.com
    KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2589004225008739
  30. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225010132-main-html.html
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    52.53.155.43/9003c45fae7689dd9660ec2260acff69b9d30974/1-s2.0-S2589004225010132-main-html.html
  31. elifesciences.org elifesciences.org
    A hierarchical pathway for assembly of the distal appendages that organize primary cilia
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    elifesciences.org/articles/85999
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Myristoylated Neuronal Calcium Sensor-1 captures the preciliary vesicle at distal appendages
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984960/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Design and Characterization of Inhibitors of Cell-Mediated Degradation of APOBEC3G That Decrease HIV-1 Infectivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12031279/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Predicting adenine base editing efficiencies in different cellular contexts by deep learning
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    pmc.ncbi.nlm.nih.gov/articles/PMC12060317/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017310/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12048556/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FUBP3 enhances HIV-1 transcriptional activity and regulates immune response pathways in T cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12005928/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S258900422500879X-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12152665/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the cuproptosis-associated gene COL22A1 in glioblastoma using EMD-1204831 and kaempferol
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    pmc.ncbi.nlm.nih.gov/articles/PMC12068844/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NSP6 of SARS-CoV-2 Dually Regulates Autophagic–Lysosomal Degradation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12028300/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nidogen-1, a Player in KMT2A-Rearranged Pediatric Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11988693/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cancer Cell-Intrinsic Type I Interferon Signaling Promotes Antitumor Immunity in Head and Neck Squamous Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12025670/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PTPN21 inhibits cell apoptosis of acute lymphoblastic leukemia induced by chemotherapeutic agents via GADD45A and JNK signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12043166/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Incomplete paralog compensation generates selective dependency on TRA2A in cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12077678/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypoxia and HIF-1 inhibition enhance lentiviral transduction efficiency: a novel strategy for gene delivery optimization
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    pmc.ncbi.nlm.nih.gov/articles/PMC12065270/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRIM22 functions as a scaffold protein for autophagy initiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12057787/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nonproteolytic ubiquitination regulates chromatin occupancy by the NCoR/SMRT/HDAC3 corepressor complex in MCF-7 breast cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067245/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MFRP is a molecular hub that organizes the apical membrane of RPE cells by engaging in interactions with specific proteins and lipids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12036977/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    mTORC1 cooperates with tRNA wobble modification to sustain the protein synthesis machinery
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    pmc.ncbi.nlm.nih.gov/articles/PMC12056009/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nuclear mitochondrial acetyl-CoA acetyltransferase 1 orchestrates natural killer cell-dependent antitumor immunity in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12034769/
  51. www.sciencedirect.com www.sciencedirect.com
    Integrative characterization of MYC RNA-binding function
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    sciencedirect.com/science/article/pii/S2666979X2500134X
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IGFBP3 enhances adipose-derived stem cell function in soft tissue injury repair via ITGB1 and ERK pathway activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12078396/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079437/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Abnormal phosphorylation of human LRH1 at Ser510 predicts poor prognosis and promotes cell viability in lung squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12016208/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11534540/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    N‐Glycosylation Modification of Fzd4 Is Essential for the Fzd4‐Wnt‐β‐Catenin Signalling Axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11997252/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to mitochondria
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    pmc.ncbi.nlm.nih.gov/articles/PMC12071194/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome-wide screen identifies genes required for erythroid differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11993733/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An unconventional autophagic pathway that inhibits ATP secretion during apoptotic cell death
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    pmc.ncbi.nlm.nih.gov/articles/PMC11986000/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oncogene-induced senescence mitochondrial metabolism and bioenergetics drive the secretory phenotype: further characterization and comparison with other senescence-inducing stimuli
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    pmc.ncbi.nlm.nih.gov/articles/PMC11997345/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nanoparticle-mediated sodium butyrate delivery for repairing hypoxic-ischemic brain injury in premature infants
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    pmc.ncbi.nlm.nih.gov/articles/PMC11994407/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overcoming antigen loss in CAR T therapy with Vγ9Vδ2 CAR T-cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12013397/
  63. www.sciencedirect.com www.sciencedirect.com
    Phagosomal RNA sensing through TLR8 controls susceptibility to tuberculosis
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    sciencedirect.com/science/article/pii/S2211124725004280
  64. www.sciencedirect.com www.sciencedirect.com
    Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124725003742
  65. www.sciencedirect.com www.sciencedirect.com
    RNA polymerase II partitioning is a shared feature of diverse oncofusion condensates
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    sciencedirect.com/science/article/pii/S0092867425004040
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    N‐terminomics and proteomics analysis of Calpain‐2 reveal key proteolytic processing of metabolic and cell adhesion proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC12023407/
  67. Apr 2025
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional characterization of all CDKN2A missense variants and comparison to in silico models of pathogenicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12002794/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Myogenic IGFBP5 levels in rhabdomyosarcoma are nourished by mesenchymal stromal cells and regulate growth arrest and apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12001570/
  70. www.biorxiv.org www.biorxiv.org
    Inhibition of EMT driver PTK6 enhances anti-tumor immune responses against triple-negative breast cancer
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    biorxiv.org/content/10.1101/2025.01.11.632044v1
  71. www.sciencedirect.com www.sciencedirect.com
    Engineered nucleocytosolic vehicles for loading of programmable editors
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    sciencedirect.com/science/article/pii/S0092867425002880
  72. www.sciencedirect.com www.sciencedirect.com
    PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124725003122
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PAR2 Serves an Indispensable Role in Controlling PAR4 Oncogenicity: The β-Catenin–p53 Axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11942634/
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Depletion of tumor-derived CXCL5 improves T cell infiltration and anti-PD-1 therapy response in an obese model of pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11931939/
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11927636/
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD301b+ monocyte-derived dendritic cells mediate resistance to radiotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11949126/
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
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    pmc.ncbi.nlm.nih.gov/articles/PMC11933316/
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    G0S2 modulates normal vitreous-induced proliferation in endothelial cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11971441/
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A human model to deconvolve genotype-phenotype causations in lung squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11971459/
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SCFA biotherapy delays diabetes in humanized gnotobiotic mice by remodeling mucosal homeostasis and metabolome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11937418/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11937597/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225003700-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC11951025/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated VRK1 levels after androgen deprivation therapy promote prostate cancer progression by upregulating YAP1 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11926012/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adenine base editing with engineered virus-like particles rescues the CFTR mutation G542X in patient-derived intestinal organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC11938077/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-cell multi-omics analysis reveals the mechanism of action of a novel antioxidant polyphenol nanoparticle loaded with STAT3 agonist in mediating cardiomyocyte ferroptosis to ameliorate age-related heart failure
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    pmc.ncbi.nlm.nih.gov/articles/PMC11955111/
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Siglec-15 is a putative receptor for porcine epidemic diarrhea virus infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC11965083/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A High-Throughput, Three-Dimensional Multiple Myeloma Model Recapitulating Tumor-Stroma Interactions for CAR-Immune Cell-Mediated Cytotoxicity Assay
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    pmc.ncbi.nlm.nih.gov/articles/PMC11967349/
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC11965392/
  89. www.sciencedirect.com www.sciencedirect.com
    RAF1 kinase contributes to autophagic lysosome reformation
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  129. Feb 2025
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  145. Jan 2025
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  156. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  163. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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