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837 Matching Annotations

Dec 2024
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

8
1. scibot 08 Dec 2024
  
  in Public
  
  RRID:CVCL_0006
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0006
2. scibot 07 Dec 2024
  
  in Public
  
  RRID:CVCL_0006
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0006
3. scibot 06 Dec 2024
  
  in Public
  
  RRID:CVCL_0006
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0006
4. scibot 05 Dec 2024
  
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  RRID:CVCL_0006
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0006
5. scibot 04 Dec 2024
  
  in Public
  
  RRID:CVCL_0006
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0006
6. scibot 03 Dec 2024
  
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  RRID:CVCL_0006
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0006
7. scibot 02 Dec 2024
  
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  RRID:CVCL_0006
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0006
8. scibot 01 Dec 2024
  
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  RRID:CVCL_0006
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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sciencedirect.com/science/article/pii/S2211124724013111
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Simple quantitation and spatial characterization of label free cellular images

1
1. scibot 06 Dec 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.heliyon.2024.e40684
  
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sciencedirect.com/science/article/pii/S2405844024167151
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B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies

1
1. scibot 02 Dec 2024
  
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  CVCL_0006
  
  DOI: 10.1016/j.ebiom.2024.105459
  
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sciencedirect.com/science/article/pii/S235239642400495X
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Macrophages are activated toward phagocytic lymphoma cell clearance by pentose phosphate pathway inhibition

1
1. scibot 02 Dec 2024
  
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  CVCL_0006
  
  DOI: 10.1016/j.xcrm.2024.101830
  
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sciencedirect.com/science/article/pii/S2666379124006013
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ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis

1
1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.114988
  
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sciencedirect.com/science/article/pii/S2211124724013391
Nov 2024
pubs.acs.org pubs.acs.org

Raspberry Ketone Attenuates Hepatic Fibrogenesis and Inflammation via Regulating the Crosstalk of FXR and PGC-1α Signaling

1
1. scibot 29 Nov 2024
  
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  RRID: CVCL_0006
  
  DOI: 10.1021/acs.jafc.4c03286
  
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pubs.acs.org/doi/10.1021/acs.jafc.4c03286
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

2
1. scibot 29 Nov 2024
  
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  RRID:CVCL_0006
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:CVCL_0006
2. scibot 28 Nov 2024
  
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  RRID:CVCL_0006
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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sciencedirect.com/science/article/pii/S2211124724013111
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Inhibition of cathepsin L ameliorates inflammation through the A20/NF-κB pathway in endotoxin-induced acute lung injury

1
1. scibot 26 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11570319/
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Involvement of Mediterranean fever gene mutations in colchicine-responsive enterocolitis: a retrospective cohort study

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1. scibot 24 Nov 2024
  
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  RRID: CVCL_0006
  
  DOI: 10.1016/j.ebiom.2024.105454
  
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2. scibot 24 Nov 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.ebiom.2024.105454
  
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sciencedirect.com/science/article/pii/S2352396424004900
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Host specific sphingomyelin is critical for replication of diverse RNA viruses

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1. scibot 24 Nov 2024
  
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  Cat# TIB-202
  
  DOI: 10.1016/j.chembiol.2024.10.009
  
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sciencedirect.com/science/article/pii/S2451945624004446
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Molecular imaging in experimental pulmonary fibrosis reveals that nintedanib unexpectedly modulates CCR2 immune cell infiltration

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1. scibot 17 Nov 2024
  
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  DOI: 10.1016/j.ebiom.2024.105431
  
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sciencedirect.com/science/article/pii/S2352396424004675
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Microbiota-induced alteration of kynurenine metabolism in macrophages drives formation of creeping fat in Crohn’s disease

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1. scibot 14 Nov 2024
  
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  Cat #: TIB-202
  
  DOI: 10.1016/j.chom.2024.10.008
  
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sciencedirect.com/science/article/pii/S1931312824003949
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Cell-autonomous targeting of arabinogalactan by host immune factors inhibits mycobacterial growth

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1. scibot 07 Nov 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.7554/eLife.92737.2
  
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elifesciences.org/reviewed-preprints/92737
Oct 2024
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Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer

1
1. scibot 09 Oct 2024
  
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  Cat# TIB-202
  
  DOI: 10.1016/j.cell.2024.09.024
  
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sciencedirect.com/science/article/pii/S0092867424010729
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Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux

1
1. scibot 05 Oct 2024
  
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  DOI: 10.1016/j.chembiol.2023.06.016
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11426993/
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Human iPSC-based disease modeling studies identify a common mechanistic defect and potential therapies for AMD and related macular dystrophies

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  TIB-202™
  
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sciencedirect.com/science/article/pii/S1534580724005331
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Rift Valley fever virus coordinates the assembly of a programmable E3 ligase to promote viral replication

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1. scibot 04 Oct 2024
  
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  DOI: 10.1016/j.cell.2024.09.008
  
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sciencedirect.com/science/article/pii/S0092867424010262
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Blocking M2-Like Macrophage Polarization Using Decoy Oligodeoxynucleotide-Based Gene Therapy Prevents Immune Evasion for Pancreatic Cancer Treatment

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1. scibot 04 Oct 2024
  
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  DOI: 10.1158/1535-7163.MCT-23-0767
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443249/
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Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance

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1. scibot 02 Oct 2024
  
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  TIB-202
  
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sciencedirect.com/science/article/pii/S1934590924003229
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Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation

1
1. scibot 02 Oct 2024
  
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  DOI: 10.1158/2326-6066.CIR-20-1043
  
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aacrjournals.org/cancerimmunolres/article/9/9/1008/666146/Overproduction-of-Gastrointestinal-5-HT-Promotes
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Cabozantinib prevents the progression of metabolic dysfunction-associated steatohepatitis by inhibiting the activation of hepatic stellate cell and macrophage and attenuating angiogenic activity

1
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sciencedirect.com/science/article/pii/S2405844024146786
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S100A9 promotes renal calcium oxalate stone formation via activating the TLR4-p38/MAPK-LCN2 signaling pathway

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  DOI: 10.1016/j.ijbiomac.2024.136178
  
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sciencedirect.com/science/article/pii/S0141813024069873
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Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application

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  DOI: 10.1038/s41467-024-52110-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11427689/
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Breadth of Fc-mediated effector function correlates with clinical immunity following human malaria challenge

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  DOI: 10.1016/j.immuni.2024.05.001
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7616646/
Sep 2024
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FEBS Press

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1. scibot 27 Sep 2024
  
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  DOI: 10.1111/febs.17245
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.17245
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Discovery and characterization of a pan-betacoronavirus S2-binding antibody

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  DOI: 10.1016/j.str.2024.08.022
  
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sciencedirect.com/science/article/pii/S0969212624003691
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SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation

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  DOI: 10.1016/j.celrep.2024.114536
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
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ZNF521 promotes acute myeloid leukemogenesis by suppressing the expression and acetylation of SMC3

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  DOI: 10.1016/j.heliyon.2024.e37528
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11415694/
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Identifying compound-protein interactions with knowledge graph embedding of perturbation transcriptomics

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  TIB-202
  
  DOI: 10.1016/j.xgen.2024.100655
  
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sciencedirect.com/science/article/pii/S2666979X24002660
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A TBK1-independent primordial function of STING in lysosomal biogenesis

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  Cat#TIB-202
  
  DOI: 10.1016/j.molcel.2024.08.026
  
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sciencedirect.com/science/article/pii/S1097276524007032
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EBV-associated epithelial cancers cells promote vasculogenic mimicry formation via a secretory cross-talk with the immune microenvironment

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  DOI: 10.7150/thno.100171
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11388080/
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Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.

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1. scibot 25 Sep 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.isci.2024.110701
  
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Repeated COVID-19 mRNA vaccination results in IgG4 class switching and decreased NK cell activation by S1-specific antibodies in older adults

1
1. scibot 18 Sep 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1186/s12979-024-00466-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11401348/
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Clofazimine inhibits innate immunity against Mycobacterium tuberculosis by NF-κB

1
1. scibot 13 Sep 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1128/msphere.00254-24
  
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Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity

1
1. scibot 10 Sep 2024
  
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  TIB-202
  
  DOI: 10.1016/j.cell.2024.08.007
  
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SARS-CoV-2 infection prior to vaccination amplifies Fc-mediated humoral profiles in an age-dependent manner

1
1. scibot 04 Sep 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.celrep.2024.114684
  
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CCL19-producing fibroblasts promote tertiary lymphoid structure formation enhancing anti-tumor IgG response in colorectal cancer liver metastasis

1
1. scibot 21 Aug 2024
  
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  CVCL_0006
  
  DOI: 10.1016/j.ccell.2024.07.006
  
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Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway

1
1. scibot 20 Aug 2024
  
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  Cat# TIB-202
  
  DOI: 10.1016/j.chembiol.2024.07.011
  
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Form-Deprivation Myopia Promotes Sclera M2-type Macrophages Polarization in Mice

1
1. scibot 20 Aug 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.bbrc.2024.150490
  
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Isolation, expansion, and adoptive transfer of human ILC2s for the treatment of mice bearing liquid and solid tumors

1
1. scibot 19 Aug 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.xpro.2024.103096
  
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Glycogen Synthase Kinase 3 inhibition controls Mycobacterium tuberculosis Infection

1
1. scibot 19 Aug 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.isci.2024.110555
  
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Modulating tumor-associated macrophage polarization by anti-maRCO mAb exerts anti-osteosarcoma effects through regulating osteosarcoma cell proliferation, migration and apoptosis

1
1. scibot 18 Aug 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1186/s13018-024-04950-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11290128/
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The Microenvironment of Solid Tumors: Components and Current Challenges of Tumor-on-a-Chip Models

1
1. scibot 14 Aug 2024
  
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  ATCC® TIB-202™
  
  DOI: 10.1089/ten.teb.2024.0088
  
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liebertpub.com/doi/10.1089/ten.teb.2024.0088
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Septins promote macrophage pyroptosis by regulating gasdermin D cleavage and ninjurin-1-mediated plasma membrane rupture

1
1. scibot 13 Aug 2024
  
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  CAT#TIB-202
  
  DOI: 10.1016/j.chembiol.2024.07.003
  
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bmccancer.biomedcentral.com bmccancer.biomedcentral.com

TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1

1
1. scibot 02 Aug 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1186/s12885-024-11898-3
  
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bmccancer.biomedcentral.com/articles/10.1186/s12885-024-11898-3
52.53.155.43 52.53.155.43

Downregulation of RCN1 promotes pyroptosis in acute myeloid leukemia cells

1
1. scibot 02 Aug 2024
  
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  RRID: CVCL_0006
  
  DOI: 10.1002/1878-0261.13521
  
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52.53.155.43/17d9d464af1d04aab32a8e6f8ff8e2dac32e6481/Molecular Oncology - 2023 - Deng-html.html
academic.oup.com academic.oup.com

Analysis of Orientia tsutsugamushi promoter activity

1
1. scibot 02 Aug 2024
  
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  TIB-202
  
  DOI: 10.1093/femspd/ftab044
  
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academic.oup.com/femspd/article-abstract/79/7/ftab044/6369350
www.cell.com www.cell.com

N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand

1
1. scibot 02 Aug 2024
  
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  JCRB0112
  
  DOI: 10.1016/j.molcel.2020.12.038
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30959-X
pubs.acs.org pubs.acs.org

Raspberry Ketone Attenuates Hepatic Fibrogenesis and Inflammation via Regulating the Crosstalk of FXR and PGC-1α Signaling

1
1. scibot 02 Aug 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1021/acs.jafc.4c03286
  
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pubs.acs.org/doi/10.1021/acs.jafc.4c03286
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Brain ischemia causes systemic Notch1 activity in endothelial cells to drive atherosclerosis

1
1. scibot 30 Jul 2024
  
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  Cat #TIB-202
  
  DOI: 10.1016/j.immuni.2024.07.002
  
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Clofazimine inhibits innate immunity against Mycobacterium tuberculosis by NF-κB

1
1. scibot 30 Jul 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1128/msphere.00254-24
  
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journals.asm.org/doi/10.1128/msphere.00254-24
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<em>Clinical & Translational Immunology</em> | ASI Journal | Wiley Online Library

1
1. scibot 30 Jul 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1002/cti2.1521
  
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onlinelibrary.wiley.com/doi/10.1002/cti2.1521
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Heterozygous Gnaq deficiency enhances Ifi202b/IFI16 and NF-κB activation in endothelial cells and exacerbates lupus nephritis pathology

1
1. scibot 27 Jul 2024
  
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  Cat#TIB-202
  
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Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5

1
1. scibot 27 Jul 2024
  
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  TIB-202
  
  DOI: 10.1016/j.cell.2024.06.037
  
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52.53.155.43 52.53.155.43

Specific targeting of cancer vaccines to antigen-presenting cells via an endogenous TLR2/6 ligand derived from cysteinyl-tRNA synthetase 1

1
1. scibot 27 Jul 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.ymthe.2024.07.014
  
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52.53.155.43/f6434e7705198cdb3a91c7e9224e0c82abe935a1/1-s2.0-S1525001624004696-main-html.html
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Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity

1
1. scibot 24 Jul 2024
  
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  Cat#TIB-202
  
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Retinoic acid enhances HIV-1 reverse transcription and transcription in macrophages via mTOR-modulated mechanisms

1
1. scibot 19 Jul 2024
  
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  Cat#ARP-9942
  
  DOI: 10.1016/j.celrep.2024.114414
  
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52.53.155.43 52.53.155.43

cir-23-0692-html.html

1
1. scibot 18 Jul 2024
  
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  DOI: 10.1158/2326-6066.cir-23-0692
  
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52.53.155.43/1f4b1703c319970f6796ecb5a8f69e90cf12a77f/cir-23-0692-html.html
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The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation

1
1. scibot 17 Jul 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.celrep.2024.114417
  
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Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling

1
1. scibot 17 Jul 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.xcrm.2024.101645
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 16 Jul 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1111/bph.16489
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
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Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication

1
1. scibot 14 Jul 2024
  
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  TIB-202
  
  DOI: 10.1016/j.isci.2024.110144
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
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Lyssavirus matrix protein inhibits NLRP3 inflammasome assembly by binding to NLRP3

1
1. scibot 12 Jul 2024
  
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  TIB-202
  
  DOI: 10.1016/j.celrep.2024.114478
  
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sciencedirect.com/science/article/pii/S2211124724008076
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Alteration of β-glucan in the emerging fungal pathogen Candida auris leads to immune evasion and increased virulence

1
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  RRID:CVCL_0006
  
  DOI: 10.1007/s00430-024-00795-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11226559/
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The hydrophobicity of the CARD8 N-terminus tunes inflammasome activation

1
1. scibot 11 Jul 2024
  
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  ATCCCat# TIB-202
  
  DOI: 10.1016/j.chembiol.2024.06.004
  
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52.53.155.43 52.53.155.43

Compartment-Specific Antibody Correlates of Protection to SARS-CoV-2 Omicron in Macaques

1
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  CVCL_0006
  
  DOI: 10.1016/j.isci.2024.110174
  
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52.53.155.43/1573cb6fd10e27e2a15aebca8b7be8bc5d8e0e6e/1-s2.0-S2589004224013993-main-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

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  DOI: 10.1158/2326-6066.CIR-23-0692
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11217734/
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Identification of high-performing antibodies for tyrosine-protein kinase SYK for use in Western Blot, immunoprecipitation and immunofluorescence

1
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  DOI: 10.12688/f1000research.140456.2
  
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Jun 2024
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Preclinical Evaluation of a Novel Series of Polyfluorinated Thalidomide Analogs in Drug-Resistant Multiple Myeloma

1
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Longitudinal humoral analysis in RSV-infected infants identifies pre-existing RSV strain-specific G and evolving cross-reactive F antibodies

1
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An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors

1
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A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML

1
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molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com

Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients

1
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Potentially functional genetic variants in interferon regulatory factor family genes are associated with colorectal cancer survival

1
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Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

1
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  TIB-202
  
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May 2024
52.53.155.43 52.53.155.43

ji2300544-html.html

1
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link.springer.com link.springer.com

Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer’s disease

1
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TUDCA alleviates atherosclerosis by inhibiting AIM2 inflammasome and enhancing cholesterol efflux capacity in macrophage

1
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IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility

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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

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Development of nitroalkene-based inhibitors to target STING-dependent inflammation

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Pathways for macrophage uptake of cell-free circular RNAs

1
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  DOI: 10.1016/j.molcel.2024.04.022
  
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FEBS Press

2
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  DOI: 10.1002/1878-0261.13659
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13659
52.53.155.43 52.53.155.43

Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers

1
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  DOI: 10.1101/2024.02.22.581558
  
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Lenvatinib-resistant hepatocellular carcinoma promotes malignant potential of tumor-associated macrophages via exosomal miR-301a-3p

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  DOI: 10.1002/ags3.12814
  
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onlinelibrary.wiley.com/doi/10.1002/ags3.12814
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Bioengineering scalable and drug-responsive in vitro human multicellular non-alcoholic fatty liver disease microtissues encapsulated in the liver extracellular matrix-derived hydrogel

1
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Atherosis-associated lnc_000048 activates PKR to enhance STAT1-mediated polarization of THP-1 macrophages to M1 phenotype

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Intratumoral delivery of the chitin-derived C100 adjuvant promotes robust STING, IFNAR, and CD8+ T cell-dependent anti-tumor immunity

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cir-23-0692-html.html

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  DOI: 10.1158/2326-6066.cir-23-0692
  
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N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation

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Multiple ubiquitin ligases protect human genome integrity by targeting cancer-associated APOBEC3 deaminases for degradation

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biorxiv.org/content/10.1101/2024.04.23.590688v1
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Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia

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Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers

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ISGylation by HERCs facilitates STING activation

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NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks

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Macrophage-coated tumor cluster aggravates hepatoma invasion and immunotherapy resistance via generating local immune deprivation

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CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo

1
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  Cat#TIB-202
  
  DOI: 10.1016/j.isci.2024.109502
  
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Enhanced plant-derived vesicles for nucleotide delivery for cancer therapy

1
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  DOI: 10.1038/s41698-024-00556-3
  
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NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation

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Acquired immune resistance is associated with interferon signature and modulation of KLF6/c-MYB transcription factors in myeloid leukemia

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  DOI: 10.1002/eji.202350717
  
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P. gingivalis-Induced TLR2 Interactome Analysis Reveals Association with PARP9

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  THP1
  
  DOI: 10.1177/00220345231222181
  
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journals.sagepub.com/doi/10.1177/00220345231222181
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Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry

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  DOI: 10.1016/j.crmeth.2024.100737
  
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ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4+ T cells in low arginine condition

1
1. scibot 27 Mar 2024
  
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Vaccination with staphylococcal protein A protects mice against systemic complications of skin infection recurrences

1
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  DOI: 10.3389/fimmu.2024.1355764
  
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BPS Publications

1
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  DOI: 10.1111/bph.16338
  
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Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib

1
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MAPK14 as a key gene for regulating inflammatory response and macrophage M1 polarization induced by ferroptotic keratinocyte in psoriasis

1
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FEBS Press

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Inhibition of G protein-coupled receptor 68 using homoharringtonine attenuates chronic kidney disease-associated cardiac impairment

1
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Identification of high-performing antibodies for tyrosine-protein kinase SYK for use in Western Blot, immunoprecipitation and immunofluorescence

2
1. scibot 29 Feb 2024
  
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Cav3.1 T-type calcium channel blocker NNC 55-0396 reduces atherosclerosis by increasing cholesterol efflux

2
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FEBS Press

1
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The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation

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SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells

1
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Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity

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Effector functions are required for broad and potent protection of neonatal mice with antibodies targeting HSV glycoprotein D

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SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination

2
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Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐PD‐1 immunotherapy in head and neck cancer

1
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Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

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  DOI: 10.1101/2023.12.12.571247
  
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Antiviral response and HIV-1 inhibition in sickle cell disease

1
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Cell-autonomous targeting of arabinogalactan by host immune factors inhibits mycobacterial growth

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Borrelia-specific antibody profiles and joint fluid antibody-dependent complement deposition distinguish antibiotic-refractory from antibiotic-responsive Lyme arthritis

2
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ncbi.nlm.nih.gov/pmc/articles/PMC10830897/
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Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells

1
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Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML

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Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M

1
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ncbi.nlm.nih.gov/pmc/articles/PMC10829726/
Jan 2024
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FEBS Press

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  DOI: 10.1002/1878-0261.13584
  
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The predictive value of BTG1 for the response of newly diagnosed acute myeloid leukemia to decitabine

1
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A guide to selecting high-performing antibodies for PLC-gamma-2 for use in Western Blot, immunoprecipitation and immunofluorescence

1
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52.53.155.43/a33385b7c9d10bfb62005bb4bfba9d33353962da/aba187d4-1be5-4d07-9805-527236a8d5be_146156_-_kathleen_southern-html.html
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Targeting cell-type-specific, choroid-peripheral immune signaling to treat age-related macular degeneration

1
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Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling

1
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  ATCCCat# TIB-202
  
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Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers

1
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  DOI: 10.1158/2767-9764.CRC-23-0299
  
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Selective Impact of Selenium Compounds on Two Cytokine Storm Players

1
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Fish oil supplementation modifies the proteome, lipidome and function of high-density lipoprotein: Findings from a trial in young healthy adults

1
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  DOI: 10.1016/j.tjnut.2024.01.007
  
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SUMOylated IL-33 in the nucleus stabilizes the transcription factor IRF1 in hepatocellular carcinoma cells to promote immune escape

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  DOI: 10.1126/scisignal.abq3362
  
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Entrectinib inhibits NLRP3 inflammasome and inflammatory diseases by directly targeting NEK7

1
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  TIB-202
  
  DOI: 10.1016/j.xcrm.2023.101310
  
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Direct translation of incoming retroviral genomes

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  DOI: 10.1038/s41467-023-44501-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10770327/
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Discovery of dual-active ethionamide boosters inhibiting the Mycobacterium tuberculosis ESX-1 secretion system

1
1. scibot 11 Jan 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.chembiol.2023.12.007
  
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Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death

1
1. scibot 11 Jan 2024
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.cell.2023.12.015
  
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sciencedirect.com/science/article/pii/S0092867423013478
Dec 2023
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Human inherited CCR2 deficiency underlies progressive polycystic lung disease

1
1. scibot 29 Dec 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.cell.2023.11.036
  
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Aedes aegypti saliva modulates inflammasome activation and facilitates flavivirus infection in vitro

1
1. scibot 21 Dec 2023
  
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  ATCCCat# TIB-202
  
  DOI: 10.1016/j.isci.2023.108620
  
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A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs

2
1. scibot 20 Dec 2023
  
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  ATCCTIB-202™
  
  DOI: 10.1016/j.xgen.2023.100460
  
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  DOI: 10.1016/j.xgen.2023.100460
  
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The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases

1
1. scibot 20 Dec 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.celrep.2023.113581
  
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Anti-inflammatory mechanisms in cancer research: Characterization of a distinct M2-like macrophage model derived from the THP-1 cell line

2
1. scibot 20 Dec 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1002/cam4.6681
  
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2. scibot 02 Dec 2023
  
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  DOI: 10.1002/cam4.6681
  
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Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis

2
1. scibot 17 Dec 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.cell.2023.11.015
  
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2. scibot 17 Dec 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.cell.2023.11.015
  
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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

1
1. scibot 17 Dec 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.celrep.2023.113560
  
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Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia

1
1. scibot 16 Dec 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1007/s11033-023-08994-1
  
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link.springer.com/article/10.1007/s11033-023-08994-1
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Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer

1
1. scibot 15 Dec 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1371/journal.pgen.1011043
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10715669/
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MYC–NFATC2 axis maintains cell cycle and mitochondrial function in AML cells

1
1. scibot 01 Dec 2023
  
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  CVCL_0006
  
  DOI: 10.1101/2023.11.15.567209
  
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biorxiv.org/content/10.1101/2023.11.15.567209v1
Nov 2023
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Airway epithelial cells and macrophages trigger IL-6-CD95/CD95L axis and mediate initial immunopathology of COVID-19

1
1. scibot 29 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.isci.2023.108366
  
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Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies

1
1. scibot 28 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.ccell.2023.11.001
  
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sciencedirect.com/science/article/pii/S1535610823003665
www.embopress.org www.embopress.org

An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions

1
1. scibot 25 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.15252/embj.2023114221
  
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embopress.org/doi/10.15252/embj.2023114221
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Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML

1
1. scibot 22 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.xcrm.2023.101290
  
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sciencedirect.com/science/article/pii/S2666379123004846
onlinelibrary.wiley.com onlinelibrary.wiley.com

Design and synthesis of bioreductive prodrugs of class I histone deacetylase inhibitors and their biological evaluation in virally transfected acute myeloid leukemia cells

1
1. scibot 17 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1002/ardp.202300536
  
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onlinelibrary.wiley.com/doi/10.1002/ardp.202300536
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Effect of Flavonoids on MCP-1 Expression in Human Coronary Artery Endothelial Cells and Impact on MCP-1-Dependent Migration of Human Monocytes

1
1. scibot 17 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.3390/ijms242216047
  
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mdpi.com/1422-0067/24/22/16047
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In situ label-free X-ray imaging for visualizing the localization of nanomedicines and subcellular architecture in intact single cells

1
1. scibot 15 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1038/s41596-023-00902-y
  
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nature.com/articles/s41596-023-00902-y
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Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis

1
1. scibot 10 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.immuni.2023.10.004
  
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Pemetrexed ameliorates Con A-induced hepatic injury by restricting M1 macrophage activation

1
1. scibot 10 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.intimp.2023.111158
  
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In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target

2
1. scibot 03 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1158/2643-3230.BCD-22-0086
  
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2. scibot 03 Nov 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1158/2643-3230.BCD-22-0086
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10150294/
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Beta-spike-containing boosters induce robust and functional antibody responses to SARS-CoV-2 in macaques primed with distinct vaccines

1
1. scibot 03 Nov 2023
  
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  CVCL_0006
  
  DOI: 10.1016/j.celrep.2023.113292
  
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Oct 2023
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Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma

1
1. scibot 28 Oct 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.xcrm.2023.101238
  
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Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria

1
1. scibot 28 Oct 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.cell.2023.09.024
  
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Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage

1
1. scibot 28 Oct 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.phymed.2023.155145
  
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Regulation of STING activity in DNA sensing by ISG15 modification

1
1. scibot 27 Oct 2023
  
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  CVCL_0006
  
  DOI: 10.1016/j.celrep.2023.113277
  
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52.53.155.43 52.53.155.43

Blocking oligomerization is the most viable strategy to inhibit STING

1
1. scibot 20 Oct 2023
  
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  DOI: 10.1101/2023.08.11.553045
  
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52.53.155.43/b51af3efb3ab194b2ea96b77566b6b4cbbb36c40/2023.08.11.553045v1.full-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells

1
1. scibot 18 Oct 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.3390/cells12192389
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
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Redox-dependent internalization of the purinergic P2Y6 receptor limits colitis progression

1
1. scibot 17 Oct 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1126/scisignal.abj0644
  
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science.org/doi/10.1126/scisignal.abj0644
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Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease

1
1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.xcrm.2023.101236
  
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Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy

1
1. scibot 13 Oct 2023
  
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  RRID:CVCL_0006
  
  DOI: 10.1016/j.molcel.2023.09.007
  
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Activation of the JNK/COX-2/HIF-1α axis promotes M1 macrophage via glycolytic shift in HIV-1 infection

1
1. scibot 12 Oct 2023
  
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  DOI: 10.26508/lsa.202302148
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10556724/
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MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis

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1. scibot 06 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113023
  
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cell.com/cell-reports/abstract/S2211-1247(23)01034-3
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Aberrant glucose metabolism underlies impaired macrophage differentiation in glycogen storage disease type Ib

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  DOI: 10.1096/fj.202300592RR
  
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Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth

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1. scibot 03 Oct 2023
  
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  DOI: 10.15252/embj.2023114032
  
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embopress.org/doi/10.15252/embj.2023114032
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Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus

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  DOI: 10.1016/j.isci.2023.107942
  
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sciencedirect.com/science/article/pii/S2589004223020199
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Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107942
  
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Impaired metabolism predicts coronary artery calcification in women with systemic lupus erythematosus

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1. scibot 28 Sep 2023
  
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  DOI: 10.1016/j.ebiom.2023.104802
  
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52.53.155.43 52.53.155.43

Design and synthesis of bioreductive prodrugs of class I histone deacetylase inhibitors and their biological evaluation in virally transfected acute myeloid leukemia cells

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1. scibot 23 Sep 2023
  
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  DOI: 10.26434/chemrxiv-2023-hrxsl
  
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52.53.155.43/8a1002beb450f633f7de93d02c258c2e26fb0d05/design-and-synthesis-of-bioreductive-prodrugs-of-class-i-histone-deacetylase-inhibitors-and-their-biological-evaluation-in-virally-transfected-acute-myeloid-leukemia-cells-html.html
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Laeverin/aminopeptidase Q induces indoleamine 2,3-dioxygenase-1 in human monocytes

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  DOI: 10.1016/j.isci.2023.107692
  
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Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment

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PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy

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Mycobacterium tuberculosis infection depressed cytotoxic T cells activity owing to decreasing NKG2C and increasing NKG2A expression

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  DOI: 10.1016/j.molimm.2023.08.014
  
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Aug 2023
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NLRP11 is a pattern recognition receptor for bacterial lipopolysaccharide in the cytosol of human macrophages

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1. scibot 26 Aug 2023
  
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  DOI: 10.1126/sciimmunol.abo4767
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10443087/

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