1,248 Matching Annotations
  1. Aug 2025
  2. www.mdpi.com www.mdpi.com
    Development and In Vitro Cytotoxicity Evaluation of Individual and Combined Injectable Solutions of Curcumin and Resveratrol Against Lung Cancer Cells
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    mdpi.com/2076-3921/14/8/983
  3. www.nature.com www.nature.com
    NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
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    nature.com/articles/s41586-025-09299-y
  4. 52.53.155.43 52.53.155.43
    2025.08.06.668996v1.full-html.html
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    52.53.155.43/9762f0542a12c1b879bb3817e6abf20525e5b06e/2025.08.06.668996v1.full-html.html
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    Nanoscale spatiotemporal cluster analysis of expressed and endogenous proteins
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    nature.com/articles/s41596-025-01209-w
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers | EMBO reports
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    pmc.ncbi.nlm.nih.gov/articles/PMC12332006/
  7. www.sciencedirect.com www.sciencedirect.com
    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    sciencedirect.com/science/article/pii/S1535610825003101
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    tiRNA: An Efficient and Controllable Gene Silencing Technology via Translation Inhibition
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    sciencedirect.com/science/article/pii/S1871678425000779
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314509/
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    Integrative analysis of lung adenocarcinoma across diverse ethnicities and exposures
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    sciencedirect.com/science/article/pii/S1535610825003174
  11. www.biorxiv.org www.biorxiv.org
    PEGylation strategies for enhanced nanoparticle delivery to tumor associated immune cells
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    biorxiv.org/content/10.1101/2025.07.23.666401v1
  12. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FBXW5 Promotes Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Through the KLF13/TROAP Signaling Pathway
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.70018
  13. Jul 2025
  14. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    3D-Printed Unibody Microfluidic Devices for Organ-on-Chip Applications
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    advanced.onlinelibrary.wiley.com/doi/10.1002/admt.202501056
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    High PER1 expression is associated with STK11 mutation and clinical biomarkers of immunotherapy resistance in lung adenocarcinoma
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    link.springer.com/article/10.1007/s00432-025-06269-9
  16. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70096
  17. www.biorxiv.org www.biorxiv.org
    Ceudovitox: a novel pseudotyped-virus screening platform to identify cell entry factors for high consequence infections
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    biorxiv.org/content/10.1101/2025.07.16.665096v1
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    Respiratory infection with Enterovirus D68 induces severe acute lung inflammation in the pediatric ferret model
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    sciencedirect.com/science/article/pii/S258900422501332X
  19. www.sciencedirect.com www.sciencedirect.com
    Direct interaction of HMGB1 with SARS-CoV-2 facilitates its infection via RAGE-dependent endocytosis
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    sciencedirect.com/science/article/pii/S2589004225013240
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    Cancer-associated fibroblast-derived fibulin-5 promotes radioresistance in non-small-cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124725007892
  21. www.biorxiv.org www.biorxiv.org
    PRMT5 activity sustains histone production to maintain genome integrity
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    biorxiv.org/content/10.1101/2025.07.03.663002v1
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PPM1M, an LRRK2-counteracting, phosphoRab12-preferring phosphatase with a potential link to Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12462683/
  23. 52.53.155.43 52.53.155.43
    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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    52.53.155.43/383127a3ba30f18153ba559aaeac9e14b54b55e6/1-s2.0-S2589004225014105-main-html.html
  24. www.frontiersin.org www.frontiersin.org
    Frontiers | miR-107-enriched exosomes promote ROS/wnt/autophagy, inhibit intracellular mycobacterial growth and attenuate lung infection
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    frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1567167/full
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Utility of CK8/18 in identifying circulating tumor cells derived from lesions in patients with non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12261347/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    68Ga-NK224 PET/CT for Noninvasive Evaluation of PD-L1 Expression and Intertumor Heterogeneity: A Translational Exploratory Study
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260512/
  27. www.sciencedirect.com www.sciencedirect.com
    Substitution of a proline residue in the frog skin host-defense peptide, figainin-2PL by D-lysine generates an analog with potent activity against antibiotic-resistant ESKAPE pathogens
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    sciencedirect.com/science/article/pii/S0196978125000919
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12257754/
  29. www.nature.com www.nature.com
    The transcriptomic fingerprint of cancer response to Tumor Treating Fields (TTFields)
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    nature.com/articles/s41420-025-02615-5
  30. www.embopress.org www.embopress.org
    Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers
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    embopress.org/doi/10.1038/s44319-025-00511-8
  31. www.nature.com www.nature.com
    Sericin-coated MnO2@CeO2 nanocatalysts enable pH-responsive and synergistic vincristine delivery for lung cancer therapy
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    nature.com/articles/s41598-025-10182-z
  32. www.sciencedirect.com www.sciencedirect.com
    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1535610825002612
  33. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70075
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12232590/
  35. www.sciencedirect.com www.sciencedirect.com
    Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379125002915
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted protein degradation of PDE4 shortforms by a novel proteolysis targeting chimera
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    pmc.ncbi.nlm.nih.gov/articles/PMC12220845/
  37. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    DNA Barcoding-Enabled Tracking of Lipid Nanoparticles: Drug-Loading-Dependent Biodistribution and Tumor Microenvironment Targeting
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202501914
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prognostic model of lung adenocarcinoma based on disulfidptosis-related genes and analysis of in vitro cell experiments for PPP1R14B in the model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12210501/
  39. www.sciencedirect.com www.sciencedirect.com
    Early innate immune response and evolution of a SARS-CoV-2 furin cleavage site inactive variant in bat cells
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    sciencedirect.com/science/article/pii/S2211124725007004
  40. www.biorxiv.org www.biorxiv.org
    Transcriptome-Driven Constraint-Based Modelling Reveals Metabolic Targets for Ovarian Cancer
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    biorxiv.org/content/10.1101/2025.06.24.661329v1
  41. Jun 2025
  42. journals.plos.org journals.plos.org
    HMGB1-BoxA gene therapy in reversing cisplatin resistance in non-small cell lung cancer
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    journals.plos.org/plosone/article
  43. journals.asm.org journals.asm.org
    Rabies virus utilizes neuropilin 2 as an endocytic receptor to trigger TGFBR1-mediated actin polymerization
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    journals.asm.org/doi/10.1128/jvi.00638-25
  44. www.sciencedirect.com www.sciencedirect.com
    Inhibition of dimeric SARS-CoV-2 Mpro displays positive cooperativity and a mixture of covalent and non-covalent binding
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    sciencedirect.com/science/article/pii/S258900422501034X
  45. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70049
  46. www.sciencedirect.com www.sciencedirect.com
    EGFR TKIs suppress MUC1 glycosylation through the PI3K/AKT/SP1/C1GALT1 pathway to enhance TnMUC1 CAR-T efficacy in EGFR-mutant NSCLC
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    sciencedirect.com/science/article/pii/S2666379125002721
  47. www.authorea.com www.authorea.com
    Harmine inhibits non-small cell lung cancer growth by targeting PDE4D and inducing ferroptosis
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    authorea.com/users/934552/articles/1305055-harmine-inhibits-non-small-cell-lung-cancer-growth-by-targeting-pde4d-and-inducing-ferroptosis
  48. 52.53.155.43 52.53.155.43
    An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
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    52.53.155.43/2a376853a698c82918e819c120184e6f0c636097/gkaf532-html.html
  49. www.sciencedirect.com www.sciencedirect.com
    Targeting ceramide synthases for the development of new antifungals
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    sciencedirect.com/science/article/pii/S0969212625002138
  50. www.sciencedirect.com www.sciencedirect.com
    PLK1-mediated PDHA1 phosphorylation drives mitochondrial dysfunction, mitophagy, and cancer progression in Cr(VI)-associated lung cancer
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    sciencedirect.com/science/article/pii/S0021925825022562
  51. www.cell.com www.cell.com
    Combination of in vivo and in vitro phosphoproteomics determines the PP2A target repertoire on proteome scale
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    cell.com/cell-reports-methods/fulltext/S2667-2375(25)00120-1
  52. www.sciencedirect.com www.sciencedirect.com
    iPSC-derived trimodal T cells engineered with CAR, TCR, and hnCD16 modalities can overcome antigen escape in heterogeneous tumors
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    sciencedirect.com/science/article/pii/S266637912500268X
  53. journals.sagepub.com journals.sagepub.com
    Holothurian Glycosaminoglycan (hGAG) Promoted Bim-Induced Apoptosis in Human Lung Adenocarcinoma A549 Cell Line Through Inhibition of Akt-Mediated FOXO3a Translocation
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    journals.sagepub.com/doi/full/10.1177/15347354251341442
  54. journals.sagepub.com journals.sagepub.com
    Neuregulin 4: A Key Regulator in Suppressing Lung Adenocarcinoma Progression
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    journals.sagepub.com/doi/full/10.1177/15330338251344424
  55. www.sciencedirect.com www.sciencedirect.com
    Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation
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    sciencedirect.com/science/article/pii/S1550413125002694
  56. www.sciencedirect.com www.sciencedirect.com
    Hyperacute response proteins synthesized on γ-tubulin-FTO-MARK4 translation microdomains regulate cancer’s acute stress response
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    sciencedirect.com/science/article/pii/S2211124725006424
  57. www.nature.com www.nature.com
    PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
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    nature.com/articles/s41388-025-03468-z
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Oncofoetal Chondroitin Sulphate Allows Identification of Tumour‐Derived Extracellular Vesicles
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    pmc.ncbi.nlm.nih.gov/articles/PMC12173530/
  59. 52.53.155.43 52.53.155.43
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    52.53.155.43/35ed6a32a02f0c19792553da120be6ff4b44593a/PDF-html.html
  60. link.springer.com link.springer.com
    Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis
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    link.springer.com/article/10.1186/s40170-025-00400-7
  61. cancer-nano.biomedcentral.com cancer-nano.biomedcentral.com
    Exosomal encapsulation of a steviol derivative SD9 to overcome TRAIL resistance as a highly effective therapy against lung cancer
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    cancer-nano.biomedcentral.com/articles/10.1186/s12645-025-00329-y
  62. link.springer.com link.springer.com
    The puzzling regulation of the interferon signaling system by the p53 tumor suppressor protein
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    link.springer.com/article/10.1007/s00018-025-05763-0
  63. 52.53.155.43 52.53.155.43
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    52.53.155.43/b06cbe40dedd846bcfb5a6430dcf8d7756ed9915/PDF-html.html
  64. www.sciencedirect.com www.sciencedirect.com
    Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket
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    sciencedirect.com/science/article/pii/S258900422400124X
  65. link.springer.com link.springer.com
    Inhibition of thioredoxin reductase 1 by evernic and vulpinic acids: a promising anticancer strategy on A549 cells
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    link.springer.com/article/10.1007/s00210-025-04363-w
  66. 52.53.155.43 52.53.155.43
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  67. 52.53.155.43 52.53.155.43
    Comparative Function Analysis of Self-amplifying mRNA and Self-amplifying DNA
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    Lipid-coated nanoparticles enhance the delivery of bacterial virulence factors as a potent toxoid vaccine platform against bacterial infections
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    sciencedirect.com/science/article/pii/S2211124725005571
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12136081/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Holothurian Glycosaminoglycan (hGAG) Promoted Bim-Induced Apoptosis in Human Lung Adenocarcinoma A549 Cell Line Through Inhibition of Akt-Mediated FOXO3a Translocation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12144356/
  71. www.cell.com www.cell.com
    Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming
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    cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Prolonged Half-Life of the p53 Missense Variant R248Q Promotes Accumulation and Heterotetramer Formation with Wild-Type p53 to Exert the Dominant-Negative Effect
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    pmc.ncbi.nlm.nih.gov/articles/PMC12127799/
  73. link.springer.com link.springer.com
    SARS-CoV-2 N protein exerts antitumor effects in NSCLC by inducing DNA damage and augmenting chemotherapeutic sensitivity
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    link.springer.com/article/10.1007/s12032-025-02771-9
  74. www.sciencedirect.com www.sciencedirect.com
    Towards implementing optimized methodologies and in-depth molecular profiling to assess the pharmacological potential of human lung fibroblast exosomes as bio-shuttles for cancer therapeutics
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    sciencedirect.com/science/article/pii/S092809872500154X
  75. www.tandfonline.com www.tandfonline.com
    Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway
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    tandfonline.com/doi/abs/10.2147/DDDT.S515409
  76. www.sciencedirect.com www.sciencedirect.com
    Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S2451945625001655
  77. May 2025
  78. www.cell.com www.cell.com
    A genome-wide base-editing screen uncovers a pivotal role of paxillin δ ubiquitination in influenza virus infection
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    cell.com/cell-reports/fulltext/S2211-1247(25)00519-4
  79. link.springer.com link.springer.com
    KDELR3 is transcriptionally activated by FOXM1 and accelerates lung adenocarcinoma growth and metastasis via inhibiting endoplasmic reticulum stress-induced cell apoptosis
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    link.springer.com/article/10.1007/s13577-025-01238-3
  80. www.nature.com www.nature.com
    Hybridization chain reaction-based DNA nanoframeworks for biosensing and therapeutic applications
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    nature.com/articles/s41596-025-01183-3
  81. www.sciencedirect.com www.sciencedirect.com
    Twist1-induced suppression of oncogene-induced senescence in non-small cell lung cancer requires the transactivation domain of Twist1
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    sciencedirect.com/science/article/pii/S1476558625000582
  82. www.sciencedirect.com www.sciencedirect.com
    Primary cilium restricts TGF-β/SMAD signaling induced RIBEs in the co-culture model.
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    sciencedirect.com/science/article/pii/S0898656825003067
  83. www.sciencedirect.com www.sciencedirect.com
    Neutrophils shape the therapeutic efficacy of sirtuin 1 activity modulators in murine influenza virus infection
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    sciencedirect.com/science/article/pii/S0925443925002637
  84. link.springer.com link.springer.com
    NECTIN4 regulates the cell surface expression of CD155 in non-small cell lung cancer cells and induces tumor resistance to PD-1 inhibitors
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    link.springer.com/article/10.1007/s00262-025-04079-z
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFN-γ-mediated suppression of ANGPT2-Tie2 in endothelial cells facilitates tumor vascular normalization during immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12075545/
  86. link.springer.com link.springer.com
    Retroelement co-option disrupts the cancer transcriptional programme
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    link.springer.com/article/10.1186/s13073-025-01479-9
  87. www.sciencedirect.com www.sciencedirect.com
    MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124725004930
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ultrahigh Dose Rate Helium Ion Beams: Minimizing Brain Tissue Damage while Preserving Tumor Control
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  176. 52.53.155.43 52.53.155.43
    Single cell variation and rapid emergence of phenotypic heterogeneity in cell lines- a cautionary tale for devotees of CRISPR-Cas9.
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    52.53.155.43/6c385708921a0bf3be8e1bc925dfecc0377aeb77/2024.09.27.615490.full-html.html
  177. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability
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    cellandbioscience.biomedcentral.com/articles/10.1186/s13578-025-01358-1
  178. link.springer.com link.springer.com
    Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types
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    link.springer.com/article/10.1038/s41598-025-88357-x
  179. Jan 2025
  180. www.sciencedirect.com www.sciencedirect.com
    TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment
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    Noncanonical inhibition of topoisomerase II alpha by oxidative stress metabolites
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    sciencedirect.com/science/article/pii/S2213231725000175
  182. www.sciencedirect.com www.sciencedirect.com
    Mina53 catalyzes arginine demethylation of p53 to promote tumor growth
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    sciencedirect.com/science/article/pii/S2211124725000130
  183. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A method to quantitatively characterize the formation and dissociation of tumor cell clusters using light transmission aggregometry
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    pmc.ncbi.nlm.nih.gov/articles/PMC11705735/