2,025 Matching Annotations
  1. Apr 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DAPK1-Mediated Parkin Inactivation Enhances Neurotoxicity via MITOL-Dependent Degradation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13053296/
  3. www.sciencedirect.com www.sciencedirect.com
    Protocol for monitoring cytoplasmic Ca2+ dynamics using Fura Red-AM on a Zeiss Axio Observer microscope
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    sciencedirect.com/science/article/pii/S266616672600122X
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    High throughput screening identifies sanguinarine chloride as a multi-faceted therapeutic agent for PRCC-TFE3 rRCC by targeting lactylation-driven VEGFB-VEGFR2 signaling and PMN-MDSC infiltration
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    sciencedirect.com/science/article/pii/S2090123226002912
  5. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70245
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70244
  7. aacrjournals.org aacrjournals.org
    TUB-040, a Homogeneous and Hydrophilic NaPi2b-Targeting ADC with Stably Linked Exatecan, Exhibits Long-lasting Antitumor Activity and a Well-Tolerated Safety Profile
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    aacrjournals.org/mct/article/24/11/1685/766863/TUB-040-a-Homogeneous-and-Hydrophilic-NaPi2b
  8. aacrjournals.org aacrjournals.org
    Identification and non-clinical characterization of SAR444200, a novel anti-GPC3 NANOBODY® T-cell engager, for the treatment of GPC3+ solid tumors
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    aacrjournals.org/mct/article/25/3/361/774799/Identification-and-Nonclinical-Characterization-of
  9. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Ligand-Induced Conformational Plasticity of the CTLH E3 Ligase Receptor GID4
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    chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cmdc.202500849
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042376/
  11. www.mdpi.com www.mdpi.com
    The ATRXt Protein Represses rDNA Transcription While Mirroring ATRX Interactions and Heterochromatin Localization
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    mdpi.com/1422-0067/27/7/3103
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MAGI3 deficiency unleashes β-catenin conformational change to drive metastatic progression and mTOR inhibitor resistance in ccRCC
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039909/
  13. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Delivery of Pleckstrin-Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202518339
  14. aacrjournals.org aacrjournals.org
    SDP-LIV1, a Novel and Optimized LIV-1 Antibody-drug Conjugate Demonstrating Superior Anti-Tumor Efficacy and Favorable Safety Profile for Treatment of Solid Tumors
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    aacrjournals.org/mct/article/25/2/322/771935/SDP-LIV1-a-Novel-and-Optimized-LIV-1-Antibody-Drug
  15. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70413
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70367
  17. Mar 2026
  18. 54.241.53.176 54.241.53.176
    2026.03.24.711053.full-html.html
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    54.241.53.176/1a2d44d5c165eaf072567ceaabb54ac10ecfb25b/2026.03.24.711053.full-html.html
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Expanded applications of bioluminescence microscopy with phasor analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13106971/
  20. www.sciencedirect.com www.sciencedirect.com
    A circRNA Neoantigen Vaccine Elicits Potent Antitumor Immunity and Synergizes with Checkpoint Blockade in Melanoma
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    sciencedirect.com/science/article/pii/S0304383526002223
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    Molecular brake on firing pattern transitions in MHbChAT neurons to mediate nicotine-withdrawal-induced anxiety
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    sciencedirect.com/science/article/pii/S0896627326001261
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    RNA binding as an emerging regulatory dimension in the type I IFN response
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    sciencedirect.com/science/article/pii/S2211124726002524
  23. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phytochemical Profiling and Mechanistic Evaluation of the Antioxidant and Anti-Inflammatory Activities of Curcuma caesia Roxb. Rhizome Extract: An Integrated In Vitro, In Vivo, and In Silico Study
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202502056
  24. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Cars2-Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202522690
  25. 54.241.53.176 54.241.53.176
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    Mitochondrial lactate venting limits oxidative stress
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    sciencedirect.com/science/article/pii/S1550413126000938
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    Plasma exosomal miR-181a-5p is linked to osteoporosis by mediating endothelial-osteoblast crosstalk and regulating bone remodeling
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    sciencedirect.com/science/article/pii/S0006291X26004250
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanisms Underlying Cedazuridine-Mediated Enhancement of Oral Decitabine Bioavailability
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    pmc.ncbi.nlm.nih.gov/articles/PMC13009415/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development and preclinical evaluation of KDTV001, an adenovirus 5-vectored trivalent HPV therapeutic vaccine targeting HPV16/18/52
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    pmc.ncbi.nlm.nih.gov/articles/PMC13051719/
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    Autoinhibitory control of MLKL governs pseudokinase domain phosphorylation and oligomerization during necroptosis
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    sciencedirect.com/science/article/pii/S2211124726002081
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    An accessory orthosteric ligand binding site in the (α3)3(β4)2 nicotinic acetylcholine receptor regulates channel activation
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    sciencedirect.com/science/article/pii/S2211124726001555
  32. www.sciencedirect.com www.sciencedirect.com
    A bispecific nanobody-drug conjugate targeting TROP2 and c-Met for low-concentration, single-dose treatment of pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126001059
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    USP25 regulates atherosclerosis by restricting RIPK1-mediated inflammatory responses
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    sciencedirect.com/science/article/pii/S2352396426000952
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    Enhanced HIF-1α cooperation by a human RORγt mutant potentiates Th17 pathogenicity
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    sciencedirect.com/science/article/pii/S2211124726002019
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    Developmental reprogramming underlies chemotherapy resistance in favorable-histology Wilms tumor
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    sciencedirect.com/science/article/pii/S2211124726001415
  36. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70499
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70379
  38. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    NIPAL1 Drives a Metabolic-Epigenetic Feedback Loop to Promote Lactate-Mediated Immune Evasion in Esophageal Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202520055
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35
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    pmc.ncbi.nlm.nih.gov/articles/PMC12979022/
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    Two translocation mechanisms drive neural stem cell dissemination into the human fetal cortex
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    sciencedirect.com/science/article/pii/S0896627326000851
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MRCKα Is a Suppressor of GEF-H1/RhoA/MRTF Signaling in Tubular Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12984664/
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    Intratumoral microbiota and host genotype cooperatively shape neutrophil cytotoxic functions in colorectal cancer
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    sciencedirect.com/science/article/pii/S193131282600051X
  43. www.biorxiv.org www.biorxiv.org
    Protease-Activated Receptor 1 as an Endogenous Model of Peptidergic Gαq-Gα12-Biased G Protein Signaling
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    biorxiv.org/content/10.64898/2026.03.03.709348v2
  44. www.nature.com www.nature.com
    Arginine methylation-dependent stabilization of SUV39H1 promotes breast cancer growth
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    nature.com/articles/s41388-026-03712-0
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MYH9 mutations differentially stabilize non-muscle myosin II filaments and induce distinct cellular aggregation phenotypes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12961093/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PKCδ Regulates DNA Damage and Cell Death through a SIRT6/Nrf2-dependent Antioxidant Response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12354018/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12953771/
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    Efficient amyloid-β degradation in Alzheimer’s disease using SPYTACs
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    sciencedirect.com/science/article/pii/S0092867426001625
  49. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A new branch of mammalian vitamin B6 metabolism: AKR1C-mediated conversion of pyridoxal to pyridoxine and 4-pyridoxolactone
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70471
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sym024 interacts with a unique epitope on the CD73 homodimer, favoring effective bivalent binding to improve anti-PD1 therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12950896/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC10069010/
  52. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226005560-main-html.html
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  53. dx.doi.org dx.doi.org
    Functional characterisation of obesity-associated MRAP2 variants on MC4R and GHSR signalling
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    dx.doi.org/10.1093/hmg/ddag010
  54. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226005705-main-html.html
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    Differential conservation analysis identifies residues defining constitutive internalization in beta-adrenergic receptors
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    sciencedirect.com/science/article/pii/S2589004226004086
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12948268/
  57. Feb 2026
  58. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Anti-Apoptotic and Anti-Oxidative Effects of DDX24 Through HO-1 Transcriptional Regulation
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500598RR
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    CPSF73 activation and 3′ RNA polymerase II pausing are lost during readthrough transcription after heat shock
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    sciencedirect.com/science/article/pii/S2211124726001178
  60. www.sciencedirect.com www.sciencedirect.com
    MEDAG functions as an A-kinase-anchoring protein in adipocytes
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    sciencedirect.com/science/article/pii/S1097276526000961
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    Broad-spectrum antiviral activity of antisense oligonucleotides targeting GBF1 against SARS-CoV-2 and influenza viruses
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    sciencedirect.com/science/article/pii/S2589004226002269
  62. 54.241.53.176 54.241.53.176
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    54.241.53.176/96468e5db9f5cc199e4221523538c77b2398c73d/1-s2.0-S2589004226004943-main-html.html
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kinesin-1 is highly flexible and adopts an open conformation in the absence of cargo
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    pmc.ncbi.nlm.nih.gov/articles/PMC12925526/
  64. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Export of miRNAs from activated macrophages is cooperative and HuR-dependent
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.70309
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    Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S2666379126000480
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    Evolutionary-guided advanced deep-learning architecture powers mammalian GPCRome agonist predictions
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    sciencedirect.com/science/article/pii/S2211124726000811
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    YAP1 Enhances Mesenchymal-Type Gene Expression in Human Adrenergic-Type Neuroblastoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12897277/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKD
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    pmc.ncbi.nlm.nih.gov/articles/PMC12900513/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD44‐Binding Peptide‐Functionalized Antibiofouling Polymer Surface for High‐Performance Separation of Human Mesenchymal Stromal Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12895219/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-Density Lipoproteins (HDLs) contribute to limiting acute tissue damage: proof of concept in a model of mercury-induced nephrotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12888430/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypokalemia and bradycardia unmask the loss-of-function phenotype of a Brugada Syndrome SCN5A mutation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12886553/
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AAV‐Driven miR‐146a Promotes Neurite Outgrowth and Axonal Regeneration in Cortical Neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12884573/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proximity labeling reveals non-catalytic interactions between DPP9 and ubiquitin signaling complexes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12876531/
  74. dx.doi.org dx.doi.org
    AMPK-mediated HCN4 channel phosphorylation contributes to age-related intrinsic bradycardia
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    dx.doi.org/10.1085/jgp.202513873
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting and dissociating HIF2α from the molecular chaperone Hsp70 triggers apoptosis in kidney cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12881505/
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    Investigation into ligand selectivity and bias at the formyl peptide receptor family
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  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    New Insights Into the Role of Polo-Like Kinase 3 in Lung Tumorigenesis
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    onlinelibrary.wiley.com/doi/full/10.1002/jcb.70084
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZNF395 is a Hypoxia-Responsive Regulator of Mitochondrial Glutaminolysis in Clear Cell Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12875648/
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12872453/
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unique Aerofoil‐Structured Microfluidics for High Throughput Lipid Nanoparticle Formulation Screening and Scale‐up
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    pmc.ncbi.nlm.nih.gov/articles/PMC12866714/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Lysine Demethylase KDM4C is an Oncogenic Driver and Regulates ERK Activity in KRAS Mutant Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12856980/
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    The pathway-independent positive allosteric modulator C1 allows for the identification of active Y4 receptor relevant positions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12858701/
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    Efficacy and safety of autologous CD5-KO anti-CD5 CAR-T cells in relapsed/refractory CD5+ hematological malignancies
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    sciencedirect.com/science/article/pii/S2666379126000017
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    Stepwise epigenetic signal integration drives adaptive programming of cytotoxic lymphocytes
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