6,202 Matching Annotations
  1. Aug 2026
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    The structural basis for LRRK2’s activation and autoinhibition
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    sciencedirect.com/science/article/pii/S0092867426008251
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    Latent effector T cells mediate immunotherapy responses in the bone marrow microenvironment
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    sciencedirect.com/science/article/pii/S1535610826003491
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70428
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    tRF-28-ZJ47D112Z4DZ suppresses gastric cancer progression via Ago2-mediated regulation of the CCND1-associated cell cycle pathway and serves as a complementary plasma biomarker
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    sciencedirect.com/science/article/pii/S2090123226006314
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    PKR engages viral RNA and intron-retained host transcripts during poxvirus infection
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    sciencedirect.com/science/article/pii/S2211124726009162
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    Integrative 3D genome and epigenomic analysis identifies TP53RK and SYBU as critical regulators of stemness and anti-tumor immunity in HCC
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    sciencedirect.com/science/article/pii/S2211124726008752
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    Shikonin promotes osteogenic differentiation of periodontal ligament stem cells by modulating the p38 MAPK/ETS transcription factor 1/cementum protein 1 axis in vitro
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    onlinelibrary.wiley.com/doi/10.1002/ccs3.70104
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    SAR and QSAR Studies of Citral-Based Derivatives Against Colletotrichum fructicola
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71542
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    Shape-Programmable Particles From Photocurable Poly(β-Amino Esters) for Drug Delivery Applications
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adfm.77616
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    Virus-induced deconjugation of ISG15 dysregulates innate immunity and cellular metabolism
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    sciencedirect.com/science/article/pii/S1074761326003067
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    Cholesterol enhances lysosome-autophagosome fusion for better α-synuclein clearance in GBA L444P-mutated Parkinson disease
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    sciencedirect.com/science/article/pii/S2211124726008788
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    Integrating functional genomics and proteomics identifies Folate Carrier SLC19A1 as a predictor of pralatrexate sensitivity in T-cell lymphoma
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    biorxiv.org/content/10.1101/2025.10.08.681217v1
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    Metabolic and transcriptional adaptations to phagocytosis in microglia sustain their functionality and regenerative properties
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    biorxiv.org/content/10.1101/2025.09.18.676800v1
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    Cortical organoids reveal human-specific role of METTL5 in neurodevelopment via regulation of CHCHD2
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    pmc.ncbi.nlm.nih.gov/articles/PMC13555456/
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    FKBP52 dictates the dual role of p53 in hepatocellular carcinoma: mutation-specific prognostic stratification and therapeutic implications
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    pmc.ncbi.nlm.nih.gov/articles/PMC13553580/
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    LRRK2 regulates synaptic function through modulation of actin cytoskeletal dynamics
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    pmc.ncbi.nlm.nih.gov/articles/PMC13446905/
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    An Acetylation-Primed SUMOylation Switch Controls RORβ Stability through a p300-SIRT1 Regulatory Axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13419597/
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    Prolonged Oxidative Stress Drives p53/p21-Mediated Senescence and Degenerative Adaptation in Kidney-Derived Cells
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    onlinelibrary.wiley.com/doi/10.1155/omcl/3094707
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    RACK1 governs a dual metabolic switch in lung adenocarcinoma through c-Src/G6PD and TRIM21/LDHA Axes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13424137/
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    Simultaneous, real-time tracking of many neuromodulatory signals with multiplexed optical recording of sensors on a micro-endoscope
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    sciencedirect.com/science/article/pii/S0896627326005374
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    Targeting host lipogenesis with a diarylamide inhibitor disrupts SARS-CoV-2 replication
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    sciencedirect.com/science/article/pii/S2589004226024892
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    Therapeutic targeting of the PRMT6/FOXK1 axis restores lipid homeostasis and ameliorates hepatic steatosis and steatohepatitis in mice
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    sciencedirect.com/science/article/pii/S2211383526005277
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    The Growth Supporting Role of ZDHHC11 Is Linked to the MEF2B–BCL6 Regulatory Circuit in Burkitt Lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13397227/
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    Deletion of neuroligins from astrocytes does not detectably alter synapse numbers or astrocyte cytoarchitecture by maturity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13436961/
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    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis
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    Improving Anti–CTLA-4 Therapies through Peptide Masking and Fragment Crystallizable Non-fucosylation: Preclinical Characterization of Three Novel Antibodies
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    SIRT1 Inhibits T-cell Infiltration and Tertiary Lymphoid Structure Formation to Promote Radioimmunotherapy Resistance
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    Modification of the Transcription Factor FOXL2 at Serines 101 and 107 Disables DNA Binding, Leads to Nucleolar Relocalization, and Rewires Granulosa‐Cell Programs
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    Persistent export bias of TDP-43 under native autoregulation links insoluble accumulation to nuclear dysfunction
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    Metabolic atlas of early human cortex reveals glycolytic remodeling and pentose phosphate pathway control of cell fate transitions
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    Protocol for high-resolution mapping of RNA-associated chromatin using chromatin isolation by RNA purification-tag
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    A CEBPB-IPO4-FASN-MAVS axis limits innate immune activation and viral pneumonia
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    Functional validation of spliceogenic COL4A3 and COL4A4 variants by minigene assays refines molecular diagnosis of Alport syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430759/
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    Genotoxic antibody-drug conjugates combined with BCL-XL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    Mapping in-cell protein contact sites reveals hijacking of paraspeckles during influenza A virus infection
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    MAPT-derived circTau6 induces tau pathogenesis and neurodegeneration by encoding Tau variants
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    nature.com/articles/s41380-026-03764-4
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    METTL7A Downregulation Drives SLC1A5-Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer
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    MCT4-mediated lactate efflux promotes STING-dependent dendritic cell antitumor immunity
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    Depletion of an immature cord blood NK subset reverses trogocytosis-driven CAR NK dysfunction
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    Posaconazole mitigates α-amanitin-induced liver injury by inhibiting STT3B-mediated glycosylation and cellular uptake
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    pmc.ncbi.nlm.nih.gov/articles/PMC13395608/
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    Multi-omic screening identifies RBMXL3 as a primate-specific RNA-binding protein and candidate regulator of RNA metabolism in human spermatogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13404310/
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    Temporal Genomic Analysis of Homogeneous Tumor Models Reveals Key Regulators of Immune Evasion in Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11873729/
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    JN.1-adapted vaccination is associated with readjustment of ancestral memory B cells toward neutralization within the JN.1 antigenic space
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    Enhanced HER2 internalization by clathrin-dependent endocytosis in non-small cell lung cancer positive for HER2 mutations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12479963/
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    Functionalizing Hydrogel Nanovials with Vesicles Mimicking Antigen-Presenting Vesicles and Cancer Exosomes Improves T Cell Capture and Activation
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    dx.doi.org/10.1021/acsnano.5c19139
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    A trifluoromethyl quinazoline inhibits hepatocellular carcinoma proliferation through HDAC1 binding and multi-target mechanisms
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    Evolution of a core ribosomal innovation in octopus
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    Design, Synthesis, In Vitro Evaluation, and Molecular Docking of 4‐Substituted Anilides as Histone Deacetylase Inhibitors and Potential Anticancer Agents
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    Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer
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  51. Jul 2026
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Integrated Cellular Computational Pipeline Decodes Luteolin to Design Possible Allosteric CDK1/CYCLIN B1 Inhibitors That Overcome Breast Cancer Stemness
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    pmc.ncbi.nlm.nih.gov/articles/PMC13414611/
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    Characterization of persistent HPV-specific activated T cells in head and neck squamous cell carcinoma
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    Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase
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    pmc.ncbi.nlm.nih.gov/articles/PMC13410807/
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    CROP2, a Retriever–PROPPIN complex mediating protein export from endosomes to the plasma membrane in human cells
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    elifesciences.org/articles/109403
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    Assessing the Clinical Relevance of BRCA1 RING Domain Variants of Uncertain Significance
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  57. 54.241.53.176 54.241.53.176
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    YBX1 Confers immunosuppressive bone metastatic traits in non-small cell lung cancer
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    Positive feedback loop via HIF-1α lactylation driven by kynurenine promotes glycolysis
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    Molecular basis of the HPV E7-ZER1 axis reveals a ligandable vulnerability in HPV-positive cancers
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    Large-scale genome structure interrogation via recombinase-mediated rearrangements of multiplexed prime edits in repetitive elements
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    nature.com/articles/s41596-026-01409-y
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    The Legionella pneumophila effector SidL is an adenylyltransferase that modifies the glycolytic intermediate 3-phosphoglycerate
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    Human GBP4 promotes TRIM21-BIP-dependent autophagy to restrict M. tuberculosis infection by preventing SORT1-mediated progranulin degradation
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    DHODH is a synthetic lethal target in PIK3CA-mutant colorectal cancer
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    A 3D genome atlas of human tonsil and the role of loop extrusion in B cell somatic hypermutation
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    science.org/doi/10.1126/science.adw4243
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    Investigating the role of baseline gut Akkermansia muciniphila and its co-metabolite palmitoleic acid in BCG vaccine efficacy: a preclinical study
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    Immunophenotype and proviral landscape of HTLV-1c infection and pulmonary disease
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    Adjuvants MPLA and SMNP induce antiviral immunity and indirectly revert HIV-1 latency
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    Uridine cytidine kinase 1 promotes phosphatidylcholine biosynthesis, facilitating SARS-CoV-2 infection
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    Subtype-resolved norepinephrine imaging with an engineered α1D-adrenergic receptor indicator
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    A targetable FTO/SLC7A11/CBS/CTH axis controls cysteine metabolism, growth and survival in NSCLC
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    science.org/doi/10.1126/sciadv.aed6463
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    UFMylation Suppresses Hepatocellular Carcinoma Metastasis by Inhibiting β-catenin-Driven Hybrid EMT and NK Cell Evasion
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    aacrjournals.org/cancerres/article/86/13/3213/786139/UFMylation-Suppresses-Hepatocellular-Carcinoma
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    Stress-Induced ADGRL4 Orchestrates Tumor Progression and Metastasis by Inhibiting YAP1 Signaling and Activating Angiogenesis
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    aacrjournals.org/cancerres/article/86/11/2743/785311/Stress-Induced-ADGRL4-Orchestrates-Tumor
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    Targeting KIF11 Degradation: Oxypeucedanin Inhibits Lung Adenocarcinoma Progression by Disrupting the MCM2-CDK1 Signaling Pathway
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    RNA exonuclease REXO4 resolves m6A-marked R-loops and suppresses anti-tumor immunity
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    <fc>DHX15</fc> affects <fc>AML1</fc>‐<fc>ETO9a</fc> splicing together with <fc>HNRNPL</fc>, <fc>RBM33</fc> in <fc>AML1</fc>‐<fc>ETO</fc>‐positive acute myeloid leukaemia
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    Microfluidic Nano-Assembly of Red-Blood-Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202504351
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    Deep learning reveals FLAD1-mediated mitochondrial metabolic reprogramming in hypoxic tumors
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    Skin-innervating glutamatergic neurons modulate aging
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    TTYH3 regulates a lysosomal chloride conductance and controls lysosomal fusion, autophagy and senescence
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    Synergistic cooperation between progranulin and Jak2/Stat3 signaling determines definitive myeloid cell fate
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    SENP2 sensitizes neurons to ferroptosis via deSUMOylation of NCOA4 following cerebral ischemia–reperfusion injury
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