5,206 Matching Annotations
  1. Jan 2026
  2. www.science.org www.science.org
    Synergistic intragenic epigenetic deregulation by IDH2 and SRSF2 mutations causes mis-splicing of key transcriptional regulators
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    science.org/doi/10.1126/sciadv.adu8292
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathogenic Gαo Mutants Drive Dominant GPCR Coupling in GNAO1 Encephalopathies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12746902/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LncRNA DANCR Activates p38/mTOR‐Mediated Autophagy via ANXA2 to Exacerbate Oxygen‐Induced Retinal Neovascularization in Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12741788/
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    Single-cell perturbations decipher ribosomal stress-surveillance regulators in type 2 diabetes
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    nature.com/articles/s42255-025-01407-6
  6. pubs.acs.org pubs.acs.org
    Slippery Liquid-Infused Porous Surfaces Using Eucalyptus Oil-Loaded Bead-on-String Nanofibers for Antibacterial, Antifungal, and Antibiofilm Applications
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    pubs.acs.org/doi/full/10.1021/acsanm.5c04912
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    ANP32A-mediated Histone 3 K27 Acetylation is Essential for Sotorasib Activity in KRAS-mutant Non-Small Cell Lung Cancer
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    sciencedirect.com/science/article/pii/S002192582502962X
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    Identification of aryl hydrocarbon receptor as a functional target that enhances astrocytic ApoE secretion
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    sciencedirect.com/science/article/pii/S2451945625003988
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    Structural and functional characterization of the antigenicity of influenza A virus hemagglutinin subtype H15
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    sciencedirect.com/science/article/pii/S2211124725015451
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    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1002/prp2.70213
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    AARS1-mediated AKR1B10 lactylation stabilizes an aerobic glycolysis-positive feedback loop to drive lenvatinib resistance in hepatocellular carcinoma
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    onlinelibrary.wiley.com/doi/full/10.1002/ctm2.70561
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    Crosstalk between the ribosome quality control-associated E3 ubiquitin ligases LTN1 and RNF10
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.70230
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    5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation
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    sciencedirect.com/science/article/pii/S266637912500610X
  14. Dec 2025
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    A TRIM21–UCHL3–ITCH–SIPA1 axis promotes colorectal cancer growth and metastasis
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    sciencedirect.com/science/article/pii/S0304383525007931
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    Paralogs of Slitrk cell adhesion molecules configure excitatory synapse specificity via distinct cellular mechanisms
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    journals.plos.org/plosbiology/article
  17. www.nature.com www.nature.com
    Deprivation of EGFR signal causes senolysis in PDAC with CDK4/6 inhibition
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    nature.com/articles/s41418-025-01634-0
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    Mitochondrial glutamine import sustains electron transport chain integrity independently of glutaminolysis in cancer
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    sciencedirect.com:5037/science/article/pii/S109727652500975X
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    Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammation
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    sciencedirect.com:5037/science/article/pii/S221112472501530X
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    Repeat-associated non-AUG translation as a common mechanism for the polyGln ataxias
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    sciencedirect.com/science/article/pii/S221112472501513X
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    Structure-Based Development of Ultra-Broad-Spectrum 3C-Like Protease Inhibitors
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202512342
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    Retroviral insertions contributed to the divergence of human and chimpanzee brains
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    biorxiv.org/content/10.64898/2025.12.12.693858v1
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanism of cotranslational modification of histones H2A and H4 by MetAP1 and NatD
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    pmc.ncbi.nlm.nih.gov/articles/PMC12716425/
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    Mechanism of cotranslational modification of histones H2A and H4 by MetAP1 and NatD
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    science.org/doi/10.1126/sciadv.aeb1017
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70295
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    Anti-FAP CAR-NK cells as a novel targeted therapy against cervical cancer and cancer-associated fibroblasts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12716053/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Downregulation of ZBTB7A/LRF increases fetal hemoglobin expression in β0-thalassemia/hemoglobin E erythroid cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12715185/
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    KRT81 promotes metastasis of colorectal cancer by acting as a protein scaffold for ezrin
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    nature.com/articles/s41388-025-03665-w
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    BET inhibitor-based combinations targeting novel dependencies in MECOM-rearranged (r) AML
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    nature.com/articles/s41375-025-02842-w
  30. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225027622-main-html.html
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    Core passive and facultative mTOR-mediated mechanisms coordinate mammalian protein synthesis and decay
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    sciencedirect.com:5037/science/article/pii/S2405471225002893
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    ZAP inhibits double-stranded RNA virus infection by degrading negative-strand RNA and blocking the elongation phase of viral protein synthesis
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    sciencedirect.com:5037/science/article/pii/S2211124725015141
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    An engineered nanosystem for reprogramming circulating malignant cells and the tumor-immune axis
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    sciencedirect.com:5037/science/article/pii/S138589472513009X
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring the Cell Biological and Functional Effects of the First Disease Associated KCC1 Genetic Variant
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    pmc.ncbi.nlm.nih.gov/articles/PMC12715662/
  35. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    F13A1-Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202518128
  36. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD-L1 Expression and Acts as a Target to Enhance Anti-PD-1 Efficacy
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202514347
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70249
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12710464/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLFN14 functions as a P-TEFb inhibitor to modulate the transcription of HIV-1 and cellular genes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12710720/
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    Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors
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    sciencedirect.com:5037/science/article/pii/S1097276525009372
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated scFv identification and CAR T cell generation for AML targeting in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC12712367/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    General trends in the calnexin-dependent expression and pharmacological rescue of clinical CFTR variants
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    pmc.ncbi.nlm.nih.gov/articles/PMC12698086/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    D3-GPC2-directed CAR T cells are safe and efficacious in preclinical models of neuroblastoma and small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12699724/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structure of the TXNL1-bound proteasome
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    pmc.ncbi.nlm.nih.gov/articles/PMC12700798/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TFE3 fusion proteins promoted the progression of Xp11.2 translocation renal cell carcinoma through post-translational modification of PDL1 by upregulating CCND1/Cyclin D1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12698746/
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    A novel β-carboline alkaloid derivative targeting MDM2-p53 pathway suppresses colorectal cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12698734/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intranasal Mosaic H1N1 Live Attenuated Influenza Vaccine Elicits Broad Cross‐Reactive Immunity and Protection Against Group 1 and 2 Influenza A Viruses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12706173/
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    Serotonin-licensed macrophages potentiate chemoresistance via inositol metabolic crosstalk in ovarian cancer
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    sciencedirect.com:5037/science/article/pii/S1550413125004954
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    Elevated calneuron-1, an accessory subunit of muscarinic receptors, induces frontotemporal dysconnectivity and schizophrenia-like deficits
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    sciencedirect.com:5037/science/article/pii/S0896627325008451
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    Lymphodepleting chemotherapy potentiates neoantigen-directed T cell therapy by enhancing antigen presentation
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    sciencedirect.com:5037/science/article/pii/S2666379125005798
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    Targeting CTGF overcomes resistance to CSF1R inhibitors by preventing CAF activation in colorectal cancer
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    sciencedirect.com:5037/science/article/pii/S2666379125005531
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    Liprin-α1 enhances PHLDB3 oncogenic function in colorectal cancer via activation of mTORC2-AKT1 pathway
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    sciencedirect.com:5037/science/article/pii/S2211124725014949
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    A 20-amino-acid Cardiovirus protein exhibits cytokine-mimicry activity to regulate viral replication
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    sciencedirect.com:5037/science/article/pii/S2211124725015128
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    Targeting TFAP2β condensation suppresses the development of esophageal squamous cell carcinoma
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  55. 54.241.53.176 54.241.53.176
    2025.12.02.691883.full-html.html
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    A cell-state axis underlying colonization in carcinomas with implications for metastasis risk prediction and interception
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    Androgen receptor contributes to radioresistance through DNA repair and autophagy in AR-positive prostate cancer cells
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    biorxiv.org/content/10.64898/2025.12.03.690226v1
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    Immune and viral surveillance of HIV-1C reservoirs in an Indian cohort
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    ARAP2 regulates responses to interferon-gamma by restricting SOCS1
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    piR-43452 suppresses bladder cancer progression and enhances gemcitabine sensitivity via GTSF1/PIWIL4-mediated LRP1 mRNA destabilization
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    Bile acids regulate lipid metabolism through selective actions on fatty acid absorption
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    Molecular mechanism of resistance to lonafarnib conferred by mutations in the cysteine-rich region of respiratory syncytial virus fusion glycoprotein and discovery of a lonafarnib-derived antiviral PROTAC
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    journals.asm.org/doi/10.1128/jvi.01487-25
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    The CEMIP Hyaluronidase is Elevated in Oligodendrocyte Progenitor Cells and Inhibits Oligodendrocyte Maturation
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    tandfonline.com/doi/abs/10.1080/17590914.2025.2600157
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    TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS
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    Downregulation of the biological macromolecule Spondin-2 disrupts maternal-fetal immune tolerance and trophoblast invasion, driving unexplained recurrent pregnancy loss
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    Microglial macrophage-derived ds-HMGB1 in DRG orchestrates neuropathic pain through immune-neural signaling
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    Genetically engineered nanovesicles based anti-EphA2/CD3 bispecific antibody promotes T cell immune response for triple negative breast cancer treatment
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    HYPK promotes N-terminal protein acetylation through rapid ribosome exchange of NatA
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    Keratinocyte differentiation transcription factor ZNF750 coordinates the development of epidermal immunocytes
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    cell.com/cell-reports/fulltext/S2211-1247(25)01420-2
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    Visualizing infection by single positive-sense RNA viruses using virus infection real-time imaging (VIRIM)
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    nature.com/articles/s41596-025-01290-1
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    Puromycin-sensitive aminopeptidase acts as an inhibitory auxiliary subunit of volume-regulated anion channels and regulates cGAMP transport
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    Autoantibody-triggered podocyte membrane budding drives autoimmune kidney disease
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    TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux
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    The inhibitory SAPS3–AMPK interaction detected in HEK293 cells is not detectable in muscle or liver from humans or mice
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    A chemical agonist and the Golgi-resident lipid PI4P activate STING by inducing transmembrane helix rearrangement
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    Amyloid-motif-dependent tau self-assembly is modulated by isoform sequence context
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    eIF3d and eIF3e mediate selective translational control of hypoxia that can be inhibited by small molecules
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    Arp2/3-dependent regulation of ciliogenesis governs adaptive distal tubular epithelial cell states in kidney disease
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    science.org/doi/10.1126/sciadv.ady1623
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    TXNIP mediates LAT1/SLC7A5 endocytosis to limit amino acid uptake in cells entering quiescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12669767/
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