486 Matching Annotations
  1. May 2025
  2. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel synthesised STAT3 inhibitor exerts potent anti-tumour activity by inducing lysosome-dependent cell death
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70071
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    Sumoylated Etv1 establishes mouse mammary cancer stem cells that support tumorigenesis by non-stem cancer cells
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    sciencedirect.com/science/article/pii/S1534580725002072
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    Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35471
  5. Apr 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RHBDF1 promotes PERK expression through the JNK/FoxO3 pathway in breast cancer cells: RHBDF1 promotes PERK expression through the JNK/FoxO3 axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11986452/
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    N-(5-(2-morpholino-4-oxo-3,4-dihydroquinazolin-8-yl)pyridin-2-yl)acylamides as novel multi-PI3K/DNA-PK/P-gp inhibitors for efficient chemosensitization and MDR alleviation
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    sciencedirect.com/science/article/pii/S0223523425004064
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    Inhibition of EMT driver PTK6 enhances anti-tumor immune responses against triple-negative breast cancer
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    biorxiv.org/content/10.1101/2025.01.11.632044v1
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    Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies
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    sciencedirect.com/science/article/pii/S1534580725001558
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    Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion
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    sciencedirect.com/science/article/pii/S1535610825001163
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    Trabectedin Enhances the Antitumor Effects of IL-12 in Triple-Negative Breast Cancer
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  15. Mar 2025
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    KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules
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    Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death
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    PAI-1-driven SFRP2high cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy
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    Metabolic engineering to facilitate anti-tumor immunity
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    cell.com/cancer-cell/abstract/S1535-6108(25)00056-X
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    TEAD inhibition alters the lung immune microenvironment and attenuates metastasis
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    biorxiv.org/content/10.1101/2025.02.26.639326v1
  22. Feb 2025
  23. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Multifunctional Docetaxel Cholesterol-Polyethylene Glycol Co-Modified Poly (N-Butyl) Cyanoacrylate Nanoparticles for Brain Tumor Therapy
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/ddr.70069
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    Bidirectional activation of stem-like programs between metastatic cancer and alveolar type 2 cells within the niche
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  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842356/
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    An epitope-directed mRNA vaccine inhibits tumor metastasis through the blockade of MICA/B α1/2 shedding
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    sciencedirect.com/science/article/pii/S2666379125000540
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    Potentiating anti-tumor immunity by re-engaging immune synapse molecules
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    Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2
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  30. aacrjournals.org aacrjournals.org
    Triple-negative breast cancer-derived extracellular vesicles promote a hepatic pre-metastatic niche via a cascade of microenvironment remodeling
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    aacrjournals.org/mcr/article/21/7/726/727474/Triple-Negative-Breast-Cancer-Derived
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    Arginine methylation of DDX3 by PRMT1 mediates mitochondrial homeostasis to promote breast cancer metastasis
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    Distinct cellular mechanisms underlie chemotherapies and PD-L1 blockade combinations in triple-negative breast cancer
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  33. Jan 2025
  34. www.biorxiv.org www.biorxiv.org
    Avoidance of pyroptosis accounts for the relatively high metastatic potential observed in early hybrid EMT states
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    biorxiv.org/content/10.1101/2025.01.26.634904v1
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    PDE4 inhibitor rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
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  36. link.springer.com link.springer.com
    GLUT1 as a generic biomarker enables near-infrared fluorescence molecular imaging guided precise intraoperative tumor detection in breast cancer
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    Inosine monophosphate dehydrogenase 2 (IMPDH2) modulates response to therapy and chemo-resistance in triple negative breast cancer
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    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
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    sciencedirect.com/science/article/pii/S1535610824004434
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    Targeting macrophage circadian rhythms with microcurrent stimulation to activate cancer immunity through phagocytic defense
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    pmc.ncbi.nlm.nih.gov/articles/PMC11671381/
  41. Dec 2024
  42. www.sciencedirect.com www.sciencedirect.com
    Neoadjuvant chemotherapy by liposomal doxorubicin boosts immune protection of tumor membrane antigens-based nanovaccine
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    Early downmodulation of tumor glycolysis predicts response to fasting-mimicking diet in triple-negative breast cancer patients
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    sciencedirect.com/science/article/pii/S1550413124004509
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    Enhanced antitumor immunity in breast cancer: Synergistic effects of ADAM10/ADAM17 inhibition, metabolic modulation, and camptothecin-loaded selenium nanoparticles
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    IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates
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    sciencedirect.com/science/article/pii/S2451945624004586
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    Mechano-dependent sorbitol accumulation supports biomolecular condensate
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  49. Nov 2024
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MicroRNA-145-5p inhibits the tumorigenesis of breast cancer through SENP2-regulated ubiquitination of ERK2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11584840/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combinatorial effects of cannabinoid receptor 1 and 2 agonists on characteristics and proteomic alteration in MDA-MB-231 breast cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11554208/
  52. Oct 2024
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophil elastase remodels mammary tumors to facilitate lung metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10987287/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic Profiling of Serum Extracellular Vesicles Identifies Diagnostic Signatures and Therapeutic Targets in Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443238/
  55. aacrjournals.org aacrjournals.org
    A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier
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    aacrjournals.org/cancerres/article/81/3/619/648134/A-High-Content-Screen-Identifies-Drugs-That
  56. aacrjournals.org aacrjournals.org
    Metformin Mitigates DPP-4 Inhibitor-Induced Breast Cancer Metastasis via Suppression of mTOR Signaling
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    aacrjournals.org/mcr/article/19/1/61/271645/Metformin-Mitigates-DPP-4-Inhibitor-Induced-Breast
  57. Sep 2024
  58. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13716
  59. www.sciencedirect.com www.sciencedirect.com
    CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway
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    sciencedirect.com/science/article/pii/S2666979X24002702
  60. www.sciencedirect.com www.sciencedirect.com
    Identifying compound-protein interactions with knowledge graph embedding of perturbation transcriptomics
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    sciencedirect.com/science/article/pii/S2666979X24002660
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    Customised design of antisense oligonucleotides targeting EGFR driver mutants for personalised treatment of non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S235239642400392X
  62. pubs.acs.org pubs.acs.org
    Chirality-Dependent Reprogramming of Macrophages
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    pubs.acs.org/doi/full/10.1021/acsnano.4c04137
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Dose Ionizing γ-Radiation Elicits the Extrusion of Neutrophil Extracellular Traps
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    Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369622/
  66. Aug 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunosuppressive CD29+ Treg accumulation in the liver in mice upon checkpoint inhibitor therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10922517/
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    Uncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization
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  69. www.sciencedirect.com www.sciencedirect.com
    Tumor-derived exosomal ICAM1 promotes bone metastasis of triple-negative breast cancer by inducing CD8+ T cell exhaustion
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    sciencedirect.com/science/article/pii/S1357272524001298
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced expression of galectin-9 in triple negative breast cancer cells following radiotherapy: Implications for targeted therapy
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35107
  71. pubs.acs.org pubs.acs.org
    Ivermectin Synergizes with Modulated Electro-hyperthermia and Improves Its Anticancer Effects in a Triple-Negative Breast Cancer Mouse Model
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  72. 52.53.155.43 52.53.155.43
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  73. transmedcomms.biomedcentral.com transmedcomms.biomedcentral.com
    iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer
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  74. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Psychologic Stress Drives Progression of Malignant Tumors via DRD2/HIF1α Signaling
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  75. www.embopress.org www.embopress.org
    Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies
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    embopress.org/doi/full/10.15252/emmm.202012716
  76. www.cell.com www.cell.com
    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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  77. Jul 2024
  78. www.cell.com www.cell.com
    Fecal microbiota transplantation improves anti-PD-1 inhibitor efficacy in unresectable or metastatic solid cancers refractory to anti-PD-1 inhibitor
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    cell.com/cell-host-microbe/abstract/S1931-3128(24)00228-2
  79. www.nature.com www.nature.com
    Surface nanocoating of bacteria as a versatile platform to develop living therapeutics
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    Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response
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    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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  82. translational-medicine.biomedcentral.com translational-medicine.biomedcentral.com
    Tumor necrosis factor receptor 2 promotes endothelial cell-mediated suppression of CD8+ T cells through tuning glycolysis in chemoresistance of breast cancer
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    translational-medicine.biomedcentral.com/articles/10.1186/s12967-024-05472-5
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a novel hybrid coumarin-hydroxamate conjugate targeting the HDAC1-Sp1-FOSL2 signaling axis for breast cancer therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11247895/
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    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
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    CDK4/6 inhibition sensitizes intracranial tumors to PD-1 blockade in preclinical models of brain metastasis
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  86. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  87. May 2024
  88. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    The temporal progression of lung immune remodeling during breast cancer metastasis
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  91. aacrjournals.org aacrjournals.org
    Spatiotemporal quantification of HER2-targeting antibody-drug conjugate bystander activity and enhancement of solid tumor penetration
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    IL-7-primed bystander CD8 tumor-infiltrating lymphocytes optimize the antitumor efficacy of T cell engager immunotherapy
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    Resf1 is a compound G4 quadruplex-associated tumor suppressor for triple negative breast cancer
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    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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    Intracellular delivery of oncolytic viruses with engineered Salmonella causes viral replication and cell death
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  195. Sep 2022
  196. www.sciencedirect.com www.sciencedirect.com
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  203. Jul 2022
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  207. Jun 2022
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  211. May 2022
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  216. Apr 2022
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  219. Mar 2022
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  225. Jan 2022
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  229. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  230. Dec 2021
  231. mcr.aacrjournals.org mcr.aacrjournals.org
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