Hypothesis

284 Matching Annotations

Jul 2021
www.sciencedirect.com www.sciencedirect.com

Increased Cholesterol Biosynthesis Is a Key Characteristic of Breast Cancer Stem Cells Influencing Patient Outcome

1
1. scibot 29 Jul 2021
  
  in Public
  
  Human breast cancer cell line, derived from metastatic site: MDA-MB-468
  
  DOI: 10.1016/j.celrep.2019.05.104
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719307430
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

LIPG signaling promotes tumor initiation and metastasis of human basal-like triple-negative breast cancer

2
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.7554/eLife.31334
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Validated
2. scibot 27 Jul 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.7554/eLife.31334
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Unrecognized
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RRIDCUR:Validated

RRIDCUR:Unrecognized

RRID:CVCL_0419

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5809145/
www.sciencedirect.com www.sciencedirect.com

Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID: CVCL_0419
  
  DOI: 10.1016/j.chembiol.2019.05.005
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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sciencedirect.com/science/article/pii/S2451945619301746
onlinelibrary.wiley.com onlinelibrary.wiley.com

Integration of whole‐genome sequencing and functional screening identifies a prognostic signature for lung metastasis in triple‐negative breast cancer

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID: CVCL_0419
  
  DOI: 10.1002/ijc.32329
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419 RRIDCUR:Unrecognized
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RRIDCUR:Unrecognized

RRID:CVCL_0419

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scibot

URL

onlinelibrary.wiley.com/doi/full/10.1002/ijc.32329
www.tandfonline.com www.tandfonline.com

Caprine herpesvirus 1 (CpHV-1) as a potential candidate for oncolytic virotherapy

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1080/15384047.2018.1504722
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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scibot

URL

tandfonline.com/doi/full/10.1080/15384047.2018.1504722
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1016/j.devcel.2017.10.027
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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ncbi.nlm.nih.gov/pmc/articles/PMC5726799/
europepmc.org europepmc.org

MELK is not necessary for the proliferation of basal-like breast cancer cells.

2
1. scibot 28 Jul 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.7554/eLife.26693
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Duplicate RRIDCUR:Validated
2. scibot 28 Jul 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.7554/eLife.26693
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Validated
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RRIDCUR:Validated

RRIDCUR:Duplicate

RRID:CVCL_0419

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scibot

URL

europepmc.org/articles/PMC5605198/
www.nature.com www.nature.com

Selective therapeutic strategy for p53-deficient cancer by targeting dysregulation in DNA repair

1
1. scibot 21 Jul 2021
  
  in Public
  
  RRID: CVCL_0419
  
  DOI: 10.1038/s42003-021-02370-0
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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scibot

URL

nature.com/articles/s42003-021-02370-0
link.springer.com link.springer.com

ARA-linker-TGFαL3: a novel chimera protein to target breast cancer cells

1
1. scibot 20 Jul 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1007/s12032-021-01546-2
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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scibot

URL

link.springer.com/article/10.1007/s12032-021-01546-2
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Repurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth

1
1. scibot 14 Jul 2021
  
  in Public
  
  CVCL_0419
  
  DOI: 10.1158/1535-7163.MCT-20-0480
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7611204/
www.sciencedirect.com www.sciencedirect.com

Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target

1
1. scibot 01 Jul 2021
  
  in Public
  
  MDA-MB-468
  
  DOI: 10.1016/j.biocel.2021.106028
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S1357272521001060
May 2021
www.sciencedirect.com www.sciencedirect.com

Peptide-tiling screens of cancer drivers reveal oncogenic protein domains and associated peptide inhibitors

1
1. scibot 29 May 2021
  
  in Public
  
  HTB-132
  
  DOI: 10.1016/j.cels.2021.05.002
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S2405471221001575
www.sciencedirect.com www.sciencedirect.com

NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells

1
1. scibot 19 May 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1016/j.xcrm.2021.100279
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S2666379121001075
www.sciencedirect.com www.sciencedirect.com

PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay

1
1. scibot 13 May 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1016/j.devcel.2021.04.019
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S1534580721003579
www.sciencedirect.com www.sciencedirect.com

Anti-tumor effect of a recombinant Bifidobacterium strain secreting a claudin-targeting molecule in a mouse breast cancer model

1
1. scibot 12 May 2021
  
  in Public
  
  HTB-132
  
  DOI: 10.1016/j.ejphar.2020.173596
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S0014299920306889
www.sciencedirect.com www.sciencedirect.com

PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1016/j.molcel.2020.08.018
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S1097276520305815
www.sciencedirect.com www.sciencedirect.com

Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis

1
1. scibot 01 May 2021
  
  in Public
  
  HTB-132
  
  DOI: 10.1016/j.cmet.2021.03.003
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S1550413121001108
www.sciencedirect.com www.sciencedirect.com

Deciphering the signaling network of breast cancer improves drug sensitivity prediction

1
1. scibot 01 May 2021
  
  in Public
  
  HTB-132
  
  DOI: 10.1016/j.cels.2021.04.002
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S2405471221001113
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets

1
1. scibot 29 Apr 2021
  
  in Public
  
  Cat#HTB-132
  
  DOI: 10.1016/j.cmet.2020.10.012
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S1550413120305453
www.sciencedirect.com www.sciencedirect.com

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

1
1. scibot 24 Apr 2021
  
  in Public
  
  HTB-132
  
  DOI: 10.1016/j.cell.2020.07.009
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S0092867420308746
www.sciencedirect.com www.sciencedirect.com

A selective p53 activator and anticancer agent to improve colorectal cancer therapy

1
1. scibot 14 Apr 2021
  
  in Public
  
  HTB-132
  
  DOI: 10.1016/j.celrep.2021.108982
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_0419
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721002965
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling

1
1. scibot 09 Apr 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.7554/eLife.64251
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_0419
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RRIDCUR:Validated

RRID:CVCL_0419

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8024022/
www.sciencedirect.com www.sciencedirect.com

Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation

1
1. scibot 07 Apr 2021
  
  in Public
  
  HTB-132
  
  DOI: 10.1016/j.cmet.2021.03.006
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S1550413121001133
www.sciencedirect.com www.sciencedirect.com

miR-770-5p regulates EMT and invasion in TNBC cells by targeting DNMT3A

1
1. scibot 03 Apr 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1016/j.cellsig.2021.109996
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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URL

sciencedirect.com/science/article/pii/S089865682100084X
Mar 2021
www.sciencedirect.com www.sciencedirect.com

SGK1 signaling promotes glucose metabolism and survival in extracellular matrix detached cells

1
1. scibot 18 Mar 2021
  
  in Public
  
  HTB-132
  
  DOI: 10.1016/j.celrep.2021.108821
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721001352
www.sciencedirect.com www.sciencedirect.com

Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer

1
1. scibot 04 Mar 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1016/j.molcel.2021.01.034
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_0419
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RRIDCUR:Validated

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S109727652100054X
Feb 2021
www.nature.com www.nature.com

Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID: CVCL_0419
  
  DOI: 10.1038/s42255-020-00325-z
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419
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RRID:CVCL_0419

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scibot

URL

nature.com/articles/s42255-020-00325-z
www.sciencedirect.com www.sciencedirect.com

An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors

1
1. scibot 24 Feb 2021
  
  in Public
  
  MDA-MB-468
  
  DOI: 10.1016/j.celrep.2021.108744
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_0419

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URL

sciencedirect.com/science/article/pii/S2211124721000577
onlinelibrary.wiley.com onlinelibrary.wiley.com

Abrogating GPT2 in triple negative breast cancer inhibits tumor growth and promotes autophagy

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1002/ijc.33456
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0419

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.33456
link.springer.com link.springer.com

Interleukin 17A promotes cell migration, enhances anoikis resistance, and creates a microenvironment suitable for triple negative breast cancer tumor metastasis

1
1. scibot 09 Feb 2021
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1007/s00262-021-02867-x
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_0419
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RRIDCUR:Validated

RRID:CVCL_0419

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scibot

URL

link.springer.com/article/10.1007/s00262-021-02867-x
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma

1
1. scibot 28 Jan 2021
  
  in Public
  
  CVCL_0419
  
  DOI: 10.1016/j.celrep.2020.108678
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
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  RRID:CVCL_0419 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0419

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sciencedirect.com/science/article/pii/S2211124720316673
Dec 2020
www.sciencedirect.com www.sciencedirect.com

Olive leaf extract impairs mitochondria by pro-oxidant activity in MDA-MB-231 and OVCAR-3 cancer cells

1
1. scibot 29 Dec 2020
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1016/j.biopha.2020.111139
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRID:CVCL_0419 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_0419

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scibot

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sciencedirect.com/science/article/pii/S0753332220313329
Nov 2020
www.sciencedirect.com www.sciencedirect.com

G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program

1
1. scibot 12 Nov 2020
  
  in Public
  
  RRID:CVCL_0419
  
  DOI: 10.1016/j.celrep.2020.108341
  
  Resource: (DSMZ Cat# ACC-738, RRID:CVCL_0419)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0419
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_0419
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RRIDCUR:Validated

RRID:CVCL_0419

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720313309
Oct 2020
www.cell.com www.cell.com

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

1
1. scibot 18 Oct 2020
  
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  RRID:CVCL_0419
  
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cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
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Elevated V-ATPase activity following PTEN loss is required for enhanced oncogenic signaling in breast cancer

1
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  RRID:CVCL_0419
  
  DOI: 10.1158/1541-7786.MCR-20-0088
  
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Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer

1
1. scibot 08 Oct 2020
  
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  MDA-MB-468
  
  DOI: 10.1016/j.celrep.2020.108231
  
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Tubulin Tyrosine Ligase Like 4 (TTLL4) overexpression in breast cancer cells is associated with brain metastasis and alters exosome biogenesis

1
1. scibot 03 Oct 2020
  
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  DOI: 10.1186/s13046-020-01712-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7528497/
Sep 2020
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Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer

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  DOI: 10.1016/j.ccell.2020.08.016
  
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Differential glucocorticoid-dependent regulation and function of the ERRFI1 gene in triple-negative breast cancer

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  RRID:CVCL_0419
  
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Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

1
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  RRID:CVCL_0419
  
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Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531

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  RRID:CVCL_0419
  
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ARX788, a Site-specific anti-HER2 Antibody Drug Conjugate, Demonstrates Potent and Selective Activity in HER2 Low and T-DM1 Resistant Breast and Gastric Cancers

1
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Engineering Elastic Nano- and Micro-Patterns and Textures for Directed Cell Motility

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A Novel Bioengineered MicroRNA-127 Prodrug Suppresses The Growth And Metastatic Potential Of Triple Negative Breast Cancer Cells

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Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity

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Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

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  DOI: 10.1016/j.cell.2020.02.019
  
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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

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  DOI: 10.1016/j.celrep.2020.107840
  
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FGF13 promotes metastasis of triple‐negative breast cancer

1
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  RRID:CVCL_0419
  
  DOI: 10.1002/ijc.32874
  
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Statin Drugs Plus Th1 Cytokines Potentiate Apoptosis and Ras Delocalization in Human Breast Cancer Lines and Combine with Dendritic Cell-Based Immunotherapy to Suppress Tumor Growth in a Mouse Model of HER-2pos Disease

1
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  DOI: 10.3390/vaccines8010072
  
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Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer

1
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  Human: MDA-MB-468
  
  DOI: 10.1016/j.celrep.2019.12.056
  
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Acetylation Stabilizes Phosphoglycerate Dehydrogenase by Disrupting the Interaction of E3 Ligase RNF5 to Promote Breast Tumorigenesis

1
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  MDA-MB-468
  
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Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment

1
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  MDA-MB-468
  
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Selective and Effective Cancer Treatments using Target‐Switchable Intracellular Bacterial Toxin Delivery Systems

1
1. scibot 30 Aug 2020
  
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  MDA‐MB‐468
  
  DOI: 10.1002/adtp.202000043
  
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onlinelibrary.wiley.com/doi/10.1002/adtp.202000043
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Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis

1
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  CVCL_0419
  
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Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling

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Mesenchymal Stem/Stromal Cell Engulfment Reveals Metastatic Advantage in Breast Cancer

1
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Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation

1
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  DOI: 10.1016/j.cmet.2019.09.009
  
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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

1
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VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells

1
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  DOI: 10.1016/j.cels.2019.05.009
  
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γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A

1
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  DOI: 10.1016/j.molcel.2019.09.007
  
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Paradigms for Precision Medicine in Epichaperome Cancer Therapy

1
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Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer

1
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Heterogeneity and Plasticity of Human Breast Cancer Cells in Response to Molecularly-Targeted Drugs

1
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  RRID:CVCL_0419
  
  DOI: 10.3389/fonc.2019.01070
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6803545/
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Untitled document

1
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  DOI: 10.1016/j.chembiol.2018.11.013
  
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Untitled document

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FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer

1
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ncbi.nlm.nih.gov/pmc/articles/PMC6425951/
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Untitled document

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1. scibot 13 Jan 2020
  
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  CVCL_0419
  
  DOI: 10.1016/j.ccell.2019.02.009
  
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Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

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1. scibot 13 Jan 2020
  
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  CVCL_0419
  
  DOI: 10.1016/j.cmet.2019.01.020
  
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Low expression of CRISP3 predicts a favorable prognosis in patients with mammary carcinoma

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1. scibot 13 Jan 2020
  
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  CVCL_0419
  
  DOI: 10.1002/jcp.28043
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcp.28043
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Untitled document

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1. scibot 12 Jan 2020
  
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  CVCL_0419
  
  DOI: 10.1016/j.celrep.2019.02.054
  
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sciencedirect.com/science/article/pii/S2211124719302335
Nov 2018
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Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy

1
1. scibot 05 Nov 2018
  
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  HTB-132
  
  Curator: @Jmenke
  
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JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance

1
1. scibot 05 Nov 2018
  
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  HTB-132
  
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Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

1
1. scibot 05 Nov 2018
  
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  HTB132
  
  Curator: @Jmenke
  
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lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

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1. scibot 05 Nov 2018
  
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  RRID:CVCL_0419
  
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LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer

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1. scibot 05 Nov 2018
  
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As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid

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1. scibot 05 Nov 2018
  
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  CVCL_0419
  
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Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1534580717308717
Nov 2017
elifesciences.org elifesciences.org

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition

1
1. scibot 08 Nov 2017
  
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  RRID:CVCL_0419
  
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Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition

1
1. scibot 08 Nov 2017
  
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  HTB-132
  
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Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer

1
1. scibot 08 Nov 2017
  
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  HTB-132
  
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GLUL Promotes Cell Proliferation in Breast Cancer

1
1. scibot 08 Nov 2017
  
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  CVCL_0419
  
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onlinelibrary.wiley.com/doi/10.1002/jcb.25775/full
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Stable and Potent Selenomab-Drug Conjugates

1
1. scibot 08 Nov 2017
  
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  MDA-MB-468
  
  Curator: @chewbeccax
  
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