391 Matching Annotations
  1. Feb 2022
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    Azadirachta indica A. Juss bark extract and its Nimbin isomers restrict β-coronaviral infection and replication
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    sciencedirect.com/science/article/pii/S0042682222000022
  3. Jan 2022
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    Transmembrane 29 (Tmem29), a Newly Identified Molecule Showed Downregulation in Hypoxic-Ischemic Brain Damage
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    mdpi.com/2673-4087/3/1/3
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    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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    sciencedirect.com/science/article/pii/S2211124722000146
  6. journals.sagepub.com journals.sagepub.com
    Carboxypeptidase E Independently Changes Microtubule Glutamylation, Dendritic Branching, and Neuronal Migration
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    journals.sagepub.com/doi/full/10.1177/17590914211062765
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    Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins
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    sciencedirect.com/science/article/pii/S0092867421014847
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Mediated Knockout of Long 3′ UTR mRNA Isoforms in mESC-Derived Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC8718760/
  9. Dec 2021
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    Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development
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    sciencedirect.com/science/article/pii/S2589004221014553
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    Circ-Hdgfrp3 shuttles along neurites and is trapped in aggregates formed by ALS-associated mutant FUS
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    sciencedirect.com/science/article/pii/S2589004221014759
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel live-cell imaging assay reveals regulation of endosome maturation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8635980/
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    Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7
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    sciencedirect.com/science/article/pii/S2211124721015485
  14. Nov 2021
  15. academic.oup.com academic.oup.com
    Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE1
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    academic.oup.com/jb/advance-article/doi/10.1093/jb/mvab094/6369789
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    Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
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    sciencedirect.com/science/article/pii/S107476132100412X
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    3D bioprinted silk fibroin hydrogels for tissue engineering
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    nature.com/articles/s41596-021-00622-1
  18. Oct 2021
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    Deficiency of ER Ca2+ sensor STIM1 in AgRP neurons confers protection against dietary obesity
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    sciencedirect.com/science/article/pii/S2211124721013358
  20. Sep 2021
  21. www.sciencedirect.com www.sciencedirect.com
    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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    sciencedirect.com/science/article/pii/S2211124721011694
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    The glycine arginine-rich domain of the RNA-binding protein nucleolin regulates its subcellular localization
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    embopress.org/doi/full/10.15252/embj.2020107158
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    Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions
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    sciencedirect.com/science/article/pii/S0896627321005808
  24. Aug 2021
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neural differentiation of glioblastoma cell lines via a herpes simplex virus thymidine kinase/ganciclovir system driven by a glial fibrillary acidic protein promoter
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    ncbi.nlm.nih.gov/pmc/articles/PMC8351974/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Degeneration of ipRGCs in Mouse Models of Huntington's Disease Disrupts Non-Image-Forming Behaviors Before Motor Impairment
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    ncbi.nlm.nih.gov/pmc/articles/PMC6381252/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucocorticoid Receptor–Tethered Mineralocorticoid Receptors Increase Glucocorticoid-Induced Transcriptional Responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC6462215/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Druggable Genome Screen Identifies Modifiers of α-Synuclein Levels via a Tiered Cross-Species Validation Approach
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    ncbi.nlm.nih.gov/pmc/articles/PMC6199406/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An Image-Based miRNA screen identifies miRNA-135s as regulators of CNS axon growth and regeneration by targeting Krüppel-like factor 4
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    ncbi.nlm.nih.gov/pmc/articles/PMC6596187/
  30. www.jneurosci.org www.jneurosci.org
    Deficiency of CPEB2-Confined Choline Acetyltransferase Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction
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    jneurosci.org/content/36/50/12661
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14623
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteolytically released Lasso/teneurin-2 induces axonal attraction by interacting with latrophilin-1 on axonal growth cones
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    ncbi.nlm.nih.gov/pmc/articles/PMC6245728/
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    Secretion of Tau via an Unconventional Non-vesicular Mechanism
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    sciencedirect.com/science/article/pii/S2211124718316826
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    Neuronal activity‐dependent local activation of dendritic unfolded protein response promotes expression of brain‐derived neurotrophic factor in cell soma
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14221/full
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    Spliceosomal component PRP-40 is a central regulator of microexon splicing
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    sciencedirect.com/science/article/pii/S2211124721008871
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14146
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    Phosphorylation of Trans-active response DNA binding protein-of 43 kDa promotes its cytoplasmic aggregation and modulates its function in tau mRNA stability and exon 10 alternative splicing
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15450
  40. elifesciences.org elifesciences.org
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  41. Jul 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease
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    sciencedirect.com/science/article/pii/S1074761319305230
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    Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS
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    sciencedirect.com/science/article/pii/S0092867419312723
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    Exon-Mediated Activation of Transcription Starts
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    sciencedirect.com/science/article/pii/S0092867419312231
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  46. elifesciences.org elifesciences.org
    Metformin reverses early cortical network dysfunction and behavior changes in Huntington’s disease
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    elifesciences.org/articles/38744
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    Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM
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    AUTACs: Cargo-Specific Degraders Using Selective Autophagy
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    Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
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    Proteomics-Based Monitoring of Pathway Activity Reveals that Blocking Diacylglycerol Biosynthesis Rescues from Alpha-Synuclein Toxicity
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    sciencedirect.com/science/article/pii/S2405471219302674
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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24559
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    Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140
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    Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis
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    SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE
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    sciencedirect.com/science/article/pii/S2211124719307600
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phosphorylation-Dependent control of arc protein by TNIK
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15440
  57. europepmc.org europepmc.org
    Inducible and reversible phenotypes in a novel mouse model of Friedreich's Ataxia.
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    europepmc.org/articles/PMC5736353/
  58. link.springer.com link.springer.com
    Phospho-substrate profiling of Epac-dependent protein kinase C activity
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    link.springer.com/article/10.1007/s11010-019-03502-1
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons
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    Regulation of Neuroregeneration by Long Noncoding RNAs
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    sciencedirect.com/science/article/pii/S1097276518307925
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated microRNA Circuits
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    ncbi.nlm.nih.gov/pmc/articles/PMC3552026/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory
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    ncbi.nlm.nih.gov/pmc/articles/PMC5293492/
  64. www.jneurosci.org www.jneurosci.org
    Deficiency of CPEB2-Confined Choline Acetyltransferase Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction
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    jneurosci.org/content/36/50/12661
  65. www.nature.com www.nature.com
    A synthetic circuit for buffering gene dosage variation between individual mammalian cells
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    nature.com/articles/s41467-021-23889-0
  66. link.springer.com link.springer.com
    Functional analyses of three different mutations in the AVP-NPII gene causing familial neurohypophyseal diabetes insipidus
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    link.springer.com/article/10.1007/s12020-021-02803-0
  67. Jun 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons
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    sciencedirect.com/science/article/pii/S2211124721006367
  69. elifesciences.org elifesciences.org
    High-fidelity, efficient, and reversible labeling of endogenous proteins using CRISPR-based designer exon insertion
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    elifesciences.org/articles/64911
  70. www.sciencedirect.com www.sciencedirect.com
    LC3B phosphorylation regulates FYCO1 binding and directional transport of autophagosomes
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    sciencedirect.com/science/article/pii/S0960982221007508
  71. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Novel reporters of mitochondria-associated membranes (MAM), MAMtrackers, demonstrate MAM disruption as a common pathological feature in amyotrophic lateral sclerosis
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100137R
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysregulation of the NRG1/ERBB pathway causes a developmental disorder with gastrointestinal dysmotility in humans
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    ncbi.nlm.nih.gov/pmc/articles/PMC7954599/
  73. May 2021
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8116049/
  75. www.sciencedirect.com www.sciencedirect.com
    Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon
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    sciencedirect.com/science/article/pii/S0896627320304906
  76. www.sciencedirect.com www.sciencedirect.com
    Protective effect of thioredoxin reductase 1 in Parkinson's disease
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    sciencedirect.com/science/article/pii/S0304394020307278
  77. Apr 2021
  78. www.sciencedirect.com www.sciencedirect.com
    Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells
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    sciencedirect.com/science/article/pii/S009286742030814X
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    A Genetic Map of the Response to DNA Damage in Human Cells
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    sciencedirect.com/science/article/pii/S0092867420306735
  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Investigating oligodendrocyte connexins: Heteromeric interactions between Cx32 and mutant or wild‐type forms of Cx47 do not contribute to or modulate gap junction function
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    onlinelibrary.wiley.com/doi/full/10.1002/glia.23999
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    Ogt controls neural stem/progenitor cell pool and adult neurogenesis through modulating Notch signaling
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    sciencedirect.com/science/article/pii/S2211124721002199
  82. Mar 2021
  83. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Extracellular signal‐regulated kinase regulates microglial immune responses in Alzheimer’s disease
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24829
  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The lipid phosphatase‐like protein PLPPR1 associates with RhoGDI1 to modulate RhoA activation in response to axon growth inhibitory molecules
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15271
  85. Feb 2021
  86. www.cell.com www.cell.com
    Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30837-6
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    Downregulation of uPAR promotes urokinase translocation into the nucleus and epithelial to mesenchymal transition in neuroblastoma
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    onlinelibrary.wiley.com/doi/10.1002/jcp.29555
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    In Vivo Repair of a Protein Underlying a Neurological Disorder by Programmable RNA Editing
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    sciencedirect.com/science/article/pii/S2211124720308597
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    Sp4 controls constitutive expression of neuronal serine racemase and NF-E2-related factor-2 mediates its induction by valproic acid
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    sciencedirect.com/science/article/abs/pii/S1874939920301802
  90. Jan 2021
  91. link.springer.com link.springer.com
    Inhibition of p38 Mitogen–Activated Protein Kinase Ameliorates HAP40 Depletion–Induced Toxicity and Proteasomal Defect in Huntington’s Disease Model
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    link.springer.com/article/10.1007/s12035-020-02280-y
  92. www.sciencedirect.com www.sciencedirect.com
    Transcriptome alterations in myotonic dystrophy frontal cortex
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    sciencedirect.com/science/article/pii/S2211124720316235
  93. www.sciencedirect.com www.sciencedirect.com
    Failure to Degrade CAT-Tailed Proteins Disrupts Neuronal Morphogenesis and Cell Survival
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    sciencedirect.com/science/article/pii/S2211124720315886
  94. Dec 2020
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    Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions
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    sciencedirect.com/science/article/pii/S2211124720314844
  96. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    DNMT3A Haploinsufficiency Results in Behavioral Deficits and Global Epigenomic Dysregulation Shared across Neurodevelopmental Disorders
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    pubmed.ncbi.nlm.nih.gov/33238114/
  97. link.springer.com link.springer.com
    Overexpression of thioredoxin reductase 1 can reduce DNA damage, mitochondrial autophagy and endoplasmic reticulum stress in Parkinson's disease
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    link.springer.com/article/10.1007/s00221-020-05979-5
  98. link.springer.com link.springer.com
    Potential role of TrkB agonist in neuronal survival by promoting CREB/BDNF and PI3K/Akt signaling in vitro and in vivo model of 3-nitropropionic acid (3-NP)-induced neuronal death
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    link.springer.com/article/10.1007/s10495-020-01645-x
  99. Nov 2020
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    Modulation of calcium signaling depends on the oligosaccharide of GM1 in Neuro2a mouse neuroblastoma cells
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    link.springer.com/article/10.1007/s10719-020-09963-7
  101. www.frontiersin.org www.frontiersin.org
    MiR34a Regulates Neuronal MHC Class I Molecules and Promotes Primary Hippocampal Neuron Dendritic Growth and Branching
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    frontiersin.org/article/10.3389/fncel.2020.573208/full
  102. www.nature.com www.nature.com
    Expression of a novel brain specific isoform of C3G is regulated during development
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    nature.com/articles/s41598-020-75813-z
  103. Oct 2020
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    The Ubiquitin Receptor ADRM1 Modulates HAP40-Induced Proteasome Activity
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    Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease
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