494 Matching Annotations
  1. Jan 2025
  2. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17374
  3. www.sciencedirect.com www.sciencedirect.com
    mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase
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    sciencedirect.com/science/article/pii/S2211124724015304
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    The design of the spheroids-based in vitro tumor model determines its biomimetic properties
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    sciencedirect.com/science/article/pii/S2772950825000056
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting macrophage circadian rhythms with microcurrent stimulation to activate cancer immunity through phagocytic defense
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    pmc.ncbi.nlm.nih.gov/articles/PMC11671381/
  6. Dec 2024
  7. www.cell.com www.cell.com
    Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine
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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00652-9
  8. www.cell.com www.cell.com
    MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity
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    cell.com/cell-reports/abstract/S2211-1247(24)01471-2
  9. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/2fb487e0ec740e682ba0aad1a706fe30bd8fc51d/PDF-html.html
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fatty Acid Derivatization and Cyclization of the Immunomodulatory Peptide RP-182 Targeting CD206high Macrophages Improve Antitumor Activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11612619/
  11. Nov 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms
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    sciencedirect.com/science/article/pii/S1074761324004941
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    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
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    sciencedirect.com/science/article/pii/S107476132400493X
  14. www.biorxiv.org www.biorxiv.org
    Biases in the Parsortix® system observed with pancreatic cancer cell lines
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    biorxiv.org/content/10.1101/2024.11.05.621344v1
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    CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
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    sciencedirect.com/science/article/pii/S1934590924003692
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    A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites
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    sciencedirect.com/science/article/pii/S0092867424012145
  17. www.sciencedirect.com www.sciencedirect.com
    Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment
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    sciencedirect.com/science/article/pii/S2211124724013238
  18. Oct 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer
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    sciencedirect.com/science/article/pii/S0092867424010729
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CALB2 drives pancreatic cancer metastasis through inflammatory reprogramming of the tumor microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11448066/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking M2-Like Macrophage Polarization Using Decoy Oligodeoxynucleotide-Based Gene Therapy Prevents Immune Evasion for Pancreatic Cancer Treatment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443249/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual-hit strategy for therapeutic targeting of pancreatic cancer in patient-derived xenograft tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11019863/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inactivation of HIPK2 attenuates KRASG12D activity and prevents pancreatic tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11437985/
  24. Sep 2024
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Altered epitopes enhance macrophage-mediated anti-tumour immunity to low-immunogenic tumour mutations
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    onlinelibrary.wiley.com/doi/10.1111/imm.13854
  26. www.sciencedirect.com www.sciencedirect.com
    mCAUSE: Prioritizing Mitochondrial Targets that Alleviate Pancreatic Cancer Cell Phenotypes
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    sciencedirect.com/science/article/pii/S2589004224021059
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two-way Dispatched function in Sonic hedgehog shedding and transfer to high-density lipoproteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC11412720/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MicroRNA-26a-5p is a reliable biomarker in the adjuvant setting for pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11407630/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia Abrogates Tumor-Suppressive Activities of C/EBPδ in Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394991/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of oxidative- and endoplasmic-reticulum-stress dependent apoptosis in pancreatic cancer cell lines by DDOST knockdown
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369111/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A common druggable signature of oncogenic c-Myc, mutant KRAS and mutant p53 reveals functional redundancy and competition among oncogenes in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11365971/
  32. Aug 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347226/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11326289/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of DPYD and the effects of DPYD suppressor luteolin combined with 5‐FU in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11331593/
  36. www.sciencedirect.com www.sciencedirect.com
    A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2211124724009835
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In Vitro and In Vivo Effects of Melatonin-Containing Combinations in Human Pancreatic Ductal Adenocarcinoma
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    onlinelibrary.wiley.com/doi/10.1111/jpi.12997
  38. www.mdpi.com www.mdpi.com
    Characterization of Chemoresistance in Pancreatic Cancer: A Look at MDR-1 Polymorphisms and Expression in Cancer Cells and Patients
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    mdpi.com/1422-0067/25/15/8515
  39. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/7b3101f3d01462bbcf14399b3becbcb8b341bb38/Molecular Oncology - 2023 - Hsieh - Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer-html.html
  40. www.researchsquare.com www.researchsquare.com
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    researchsquare.com/
  41. www.embopress.org www.embopress.org
    Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies
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    embopress.org/doi/full/10.15252/emmm.202012716
  42. Jul 2024
  43. 52.53.155.43 52.53.155.43
    Cetylpyridinium chloride triggers paraptosis to suppress pancreatic tumor growth via the ERN1-MAP3K5-p38 pathway
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    52.53.155.43/3dc7aeecc5cd1b453f882be50c33db8a703a1bae/1-s2.0-S2589004224018236-main-html.html
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    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    sciencedirect.com/science/article/pii/S1535610824002174
  45. www.thelancet.com www.thelancet.com
    Biomarker screen for efficacy of oncolytic virotherapy in patient-derived pancreatic cancer cultures
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00254-8/abstract
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of autophagy induced by tetrandrine promotes the accumulation of reactive oxygen species and sensitizes efficacy of tetrandrine in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11238362/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11230627/
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pantoprazole and riluzole target H+/K+-ATPases and pH-sensitive K+ channels in pancreatic cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35076
  49. www.sciencedirect.com www.sciencedirect.com
    The YY1-CPT1C signaling axis modulates the proliferation and metabolism of pancreatic tumor cells under hypoxia
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    sciencedirect.com/science/article/pii/S0006295224004052
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11190739/
  51. Jun 2024
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Comparing in vitro cytotoxic drug sensitivity in colon and pancreatic cancer using 2D and 3D cell models: Contrasting viability and growth inhibition in clinically relevant dose and repeated drug cycles
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    onlinelibrary.wiley.com/doi/10.1002/cam4.7318
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysregulation of a Subset of Circulating and Vesicle-Associated miRNA in Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11130804/
  54. May 2024
  55. www.biorxiv.org www.biorxiv.org
    ADRA2A promotes the classical/progenitor subtype and reduces disease aggressiveness of pancreatic cancer
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    biorxiv.org/content/10.1101/2024.03.12.584316v1
  56. www.sciencedirect.com www.sciencedirect.com
    mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway
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    sciencedirect.com/science/article/pii/S1097276524003939
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11194014/
  58. 52.53.155.43 52.53.155.43
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    52.53.155.43/97841ca504d9556b3965877911b65905cd7f6735/2024.02.18.580900v1.full-html.html
  59. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin-mediated regulation of APE2 protein abundance
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    sciencedirect.com/science/article/pii/S0021925824018386
  60. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Disrupting the interaction between a p53 gain-of-function mutant and the transcriptional co-activator PC4 reverses drug resistance in cancer cells
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14890
  61. www.sciencedirect.com www.sciencedirect.com
    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2211124724005047
  62. Apr 2024
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BUB1 Promotes Gemcitabine Resistance in Pancreatic Cancer Cells by Inhibiting Ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11048608/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11044319/
  65. www.sciencedirect.com www.sciencedirect.com
    Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases
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    sciencedirect.com/science/article/pii/S2666379124001927
  66. jhoonline.biomedcentral.com jhoonline.biomedcentral.com
    Heterodimerization of T cell engaging bispecific antibodies to enhance specificity against pancreatic ductal adenocarcinoma
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    jhoonline.biomedcentral.com/articles/10.1186/s13045-024-01538-5
  67. www.sciencedirect.com www.sciencedirect.com
    QDPR deficiency drives immune suppression in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1550413124001190
  68. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin ligase TRIM15 promotes the progression of pancreatic cancer via the upregulation of the IGF2BP2-TLR4 axis
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    sciencedirect.com/science/article/pii/S0925443924001728
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34960
  70. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13609
  71. www.sciencedirect.com www.sciencedirect.com
    The UBE2F-CRL5ASB11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells
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    sciencedirect.com/science/article/pii/S1534580724001837
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Non-Viral DNA Delivery System Consisting of Multifunctional Chimaeric Peptide Fused with Zinc Finger Protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC10981093/
  73. Mar 2024
  74. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  75. www.sciencedirect.com www.sciencedirect.com
    Hyperthermia improves gemcitabine sensitivity of pancreatic cancer cells by suppressing the EFNA4/β-catenin axis and activating dCK
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    sciencedirect.com/science/article/pii/S2405844024045195
  76. academic.oup.com academic.oup.com
    LMO3 is a suppressor of the basal-like/squamous subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism
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    academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgae011/7608949
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10924943/
  78. www.sciencedirect.com www.sciencedirect.com
    PRMT1 promotes pancreatic cancer development and resistance to chemotherapy
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    sciencedirect.com/science/article/pii/S2666379124001058
  79. Feb 2024
  80. 52.53.155.43 52.53.155.43
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  81. aacrjournals.org aacrjournals.org
    Mitochondrial translocase TOMM22 is overexpressed in pancreatic cancer and promotes aggressive growth by modulating mitochondrial protein import and function
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    aacrjournals.org/mcr/article/22/2/197/733695/Mitochondrial-Translocase-TOMM22-Is-Overexpressed
  82. aacrjournals.org aacrjournals.org
    Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma
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    aacrjournals.org/clincancerres/article/29/24/5183/731660/Nuclear-GRP78-Promotes-Metabolic-Reprogramming-and
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    An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth
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    52.53.155.43/d64025fcba7405c73976a9e0dc65e9989e0d835f/2023.08.23.554263v1.full-html.html
  84. 52.53.155.43 52.53.155.43
    Identification of FOXP3+ epithelial cells contributing to pancreatic proliferation and angiogenesis
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    52.53.155.43/a4875dd9547eaa8b044abee79367d9ba9aa4f8c4/gong-et-al-2024-identification-of-foxp3-epithelial-cells-contributing-to-pancreatic-proliferation-and-angiogenesis-html.html
  85. www.sciencedirect.com www.sciencedirect.com
    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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    sciencedirect.com/science/article/pii/S2666379124000570
  86. www.sciencedirect.com www.sciencedirect.com
    Tiliroside disrupted iron homeostasis and induced ferroptosis via directly targeting calpain-2 in pancreatic cancer cells
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    sciencedirect.com/science/article/pii/S0944711324000576
  87. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16289
  88. journals.physiology.org journals.physiology.org
    Identification of FOXP3+ epithelial cells contributing to pancreatic proliferation and angiogenesis
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    journals.physiology.org/doi/10.1152/ajpcell.00461.2023
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849765/
  90. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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    sciencedirect.com/science/article/pii/S1097276524000480
  91. www.sciencedirect.com www.sciencedirect.com
    Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy
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    sciencedirect.com/science/article/abs/pii/S0304383524000892
  92. Jan 2024
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCDC85A is regulated by miR-224-3p and augments cancer cell resistance to endoplasmic reticulum stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10391547/
  94. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17058
  95. link.springer.com link.springer.com
    Machine Learning Developed a MYC Expression Feature-Based Signature for Predicting Prognosis and Chemoresistance in Pancreatic Adenocarcinoma
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    link.springer.com/article/10.1007/s10528-023-10625-0
  96. www.mdpi.com www.mdpi.com
    Multi-Algorithm Analysis Reveals Pyroptosis-Linked Genes as Pancreatic Cancer Biomarkers
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    mdpi.com/2072-6694/16/2/372
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  113. Oct 2023
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  117. Sep 2023
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  126. Aug 2023
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  131. Jul 2023
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  135. Jun 2023
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  140. May 2023
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  147. Apr 2023
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  153. Jan 2023
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  157. Dec 2022
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  163. Nov 2022
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  169. Oct 2022
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  174. Sep 2022
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  180. Aug 2022
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  185. Jul 2022
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  190. Jun 2022
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  192. May 2022
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  196. Apr 2022
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  200. Mar 2022
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  205. Feb 2022
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  224. Nov 2021
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  230. Oct 2021
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