7,108 Matching Annotations
  1. Aug 2025
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    Molecular and spatial analysis of ganglion cells on retinal flatmounts identifies perivascular neurons resilient to glaucoma
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    sciencedirect.com/science/article/pii/S0896627325005525
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    IL‐17 Stimulates Sensory Neurons and Sensitises Colonic Afferents to Noxious Stimuli in a PI3K Dependent Manner in Male Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12362332/
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    A preclinical model for the identification of therapeutically active transgenes in local cancer immunotherapy
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    tandfonline.com/doi/full/10.1080/2162402X.2025.2543620
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    Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer
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    biorxiv.org/content/10.1101/2025.08.10.669554v1
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    Developmental outflow tract abnormalities of Jag1-deficient mice are associated with abnormal ventricular activation and desynchronized contraction
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    biorxiv.org/content/10.1101/2025.08.08.669322v1
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    Surgical Removal of Visceral Adipose Tissue has Therapeutic Benefit in Male APPNL-F Mice
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    biorxiv.org/content/10.1101/2025.08.07.669175v1
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    NAIP/NLRC4 inflammasome dynamics in murine enteroids are tuned by NAIP ligand concentration and epithelial cell differentiation
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    sciencedirect.com/science/article/pii/S2211124725009143
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    Breast milk IgG engages the mouse neonatal immune system to instruct responses to gut antigens
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    science.org/doi/10.1126/science.ado5294
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    CD11b Activation Reduces Myeloid Brain Infiltration and Mitigates Synucleinopathy in a Model of Parkinson’s Disease
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    Promoter- and enhancer-dependent cohesin loading initiates chromosome looping to fold Tcrb loci for long-range recombination
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    Transcriptomic architecture of weak versus strong contextual fear extinction learning uncovers extinction-suppressive role of Tia1
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    Gut microbiome profiling in Eµ-TCL1 mice reveals intestinal changes and a dysbiotic signature specific to chronic lymphocytic leukemia
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    Yes-associated Protein Induces Age-dependent Inflammatory Signaling in the Pulmonary Endothelium
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    Functional and epitope specific monoclonal antibody discovery directly from immune sera using cryo-EM
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    Traction force and mechanosensitivity mediate species-specific implantation patterns in human and mouse embryos
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    Traction force and mechanosensitivity mediate species-specific implantation patterns in human and mouse embryos
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    Spatiotemporal dynamics of CXCL10 encode contextual immune information revealed by the genetically encoded fluorescent sensor
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    Long-lasting and fast methylglyoxal-scavenging peptide CycK(Myr)R4E alleviates chronic pain in type 2 diabetic mice
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    The Lipid Hydrolase ABHD6 is a Therapeutic Target in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)-Related Hepatocellular Carcinoma
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    TRPV1+ neurons promote cutaneous immunity against Schistosoma mansoni
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    Multi-omic analysis reveals retinoic acid molecular drivers for dermal fibrosis and regenerative repair in the skin
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    Succinate preserves CD8+ T cell fitness to augment antitumor immunity
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    Fc-optimized CD40 agonistic antibody elicits tertiary lymphoid structure formation and systemic antitumor immunity in metastatic cancer
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    Coordination of distinct sources of excitatory inputs enhances motion selectivity in the mouse visual thalamus
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    Inhibition of Hedgehog Signaling Ameliorates Severity of Chronic Pancreatitis in Experimental Mouse Models
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    Glucose transporter 1 is essential to maintain brain endothelial cell homeostasis under hyperglycemia condition | American Journal of Physiology-Cell Physiology | American Physiological Society
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    Ribo-ITP expands the translatome of limited input samples
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    Protocol for recording and analyzing neuronal network activity ex vivo with multi-electrode arrays in mouse brain tissue
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    Anti‑obesity Effects of Lactiplantibacillus plantarum ZNFL-1 by Modulating Gut Microbiota and Lipid Metabolism in High‑Fat Diet‑Induced Mice
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    Diet-induced obesity induces oxidative stress and enhances H3K4me3 levels, driving nonresolving inflammation and myelopoiesis in hematopoietic stem and progenitor cells
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    Dopaminergic projections to the prefrontal cortex are critical for rapid threat avoidance learning
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    Clonal expansion and diversification of germinal center and memory B cell responses to booster immunization in primates
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    Subsecond Analysis of Locomotor Activity in Parkinsonian Mice
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    Conditional deletion of TRPC1 channel modulates synaptic plasticity, long term depression, and memory extinction in Fragile X Syndrome mice.
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    VIVIT: Resolving trans-scale volumetric biological architectures via ionic glassy tissue
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    Epigenetic Regulation of DAPK1 and Netrin-1 Drives Diabetic Encephalopathy
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    LMO2 regulates epithelial-mesenchymal plasticity of mammary epithelial cells
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    Phase synchrony between prefrontal noradrenergic and cholinergic signals indexes inhibitory control
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    Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome
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    Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression
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    Triple-Negative Breast Cancer Cells Activate Sensory Neurons via TRPV1 to Drive Nerve Outgrowth and Tumor Progression
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    Separable dorsal raphe dopamine projections mimic the facets of a loneliness-like state
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    Significance of FXa and its receptor PAR2 for the growth of colon cancer cells in vitro and in vivo
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    Establishing a social behavior paradigm for female mice
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    Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control
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    CD138 and APRIL regulate plasma cell survival, competition, and retention in the bone marrow niche
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    Activation of the non-canonical Wnt5a signaling pathway following optic nerve injury induces time-dependent changes in pro- and anti-inflammatory gene expression
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    Tet3-mediated DNA demethylation is essential for maintaining the dedifferentiation capacity of mammalian Müller glia
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    Tumor cell-intrinsic Decr2 regulates ferroptosis and immunotherapy efficacy
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    T cells Instruct Immune Checkpoint Inhibitor Therapy Resistance in Tumors Responsive to IL-1 and TNFα Inflammation
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    N-(4-Bromo-2,5-Dimethoxyphenethyl)-6-(4-Phenylbutoxy)Hexan-1-Amine (XOB): A Novel Phenylalkylamine Antagonist of Serotonin 2A Receptors and Voltage-Gated Sodium Channels
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    Transient receptor potential ankyrin 1 channel modulates the abuse-related mechanisms of methamphetamine through interaction with dopamine transporter
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    A molecular and spinal circuit basis for the functional segregation of itch and pain
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    Subunit-specific roles of LRRC8 proteins in determining glutamate permeability of astrocytic volume-regulated anion channels
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    biorxiv.org/content/10.1101/2025.07.24.666608v1
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    Visual loom caused by self-movement or object-movement elicits distinct responses in mouse superior colliculus
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    Uropathogenic Escherichia coli niche occupancy determines the effects of mucosal vaccine against FimH
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    Design of soluble Notch agonists that drive T cell development and boost immunity
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    Staphylococcus aureus exploits lipoic acid salvage to combat host oxidative stress
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    Spatial transcriptomic profiling uncovers the molecular effects of the neurotoxicant polychlorinated biphenyls (PCBs) in the brains of adult mice
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    Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
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    Aggrecan protects against plaque accumulation and is essential for proper microglial responses to plaques
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    AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact
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    Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells
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  70. Jul 2025
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    Comparative single-cell lineage tracing identifies distinct adipocyte precursor dynamics in skin and inguinal fat
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    Infection promotes Ser-214 phosphorylation important for generation of cytotoxic tau variants
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    BRD9 inhibition overcomes oncolytic virus therapy resistance in glioblastoma
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    Coupling IL-2 with IL-10 to mitigate toxicity and enhance antitumor immunity
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    Cell-specific wiring routes information flow through hippocampal CA3
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    Sex and Genotype Affect Mouse Hippocampal Gene Expression in Response to Blast-Induced Traumatic Brain Injury
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    Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism
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    Cell type–dependent role of transforming growth factor-β signaling on postnatal neural stem cell proliferation and migration
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    Establishing Preclinical Quantitative Parameters for Future Assessment of Corneal and Retinal Therapeutics for Aniridia
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70135
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    Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
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    TREM2‐Mediated Myeloid Cells Protect Against Pathological Choroidal Neovascularization
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    Triglycerides are an important fuel reserve for synapse function in the brain
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    Impaired vasopressin neuromodulation of the lateral septum leads to social behavior deficits in Shank3B+/- male mice
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    Gut substrate trap of D-lactate from microbiota improves blood glucose and fatty liver disease in obese mice
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    Manufacturing of CRISPR-edited primary mouse CAR T cells for cancer immunotherapy
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    nature.com/articles/s41596-025-01208-x
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    Sex difference in the effects of ventral pallidum vasopressin 1a receptor partial knockdown on social behavior in mice
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    Caloric restriction protects from acute and chronic kidney injury by inhibiting monocyte recruitment
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