10,818 Matching Annotations
  1. Sep 2024
  2. www.frontiersin.org www.frontiersin.org
    Endoplasmic reticulum associated degradation preserves neurons viability by maintaining endoplasmic reticulum homeostasis
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    1. scibot 26 Sep 2024
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      DOI: 10.3389/fnins.2024.1437854

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    frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2024.1437854/full
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reconstitution of the Multiple Myeloma Microenvironment Following Lymphodepletion with BCMA CAR-T Therapy
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1158/1078-0432.CCR-24-0352

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    ncbi.nlm.nih.gov/pmc/articles/PMC11393544/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Dose Ionizing γ-Radiation Elicits the Extrusion of Neutrophil Extracellular Traps
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1158/1078-0432.CCR-23-3860

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    ncbi.nlm.nih.gov/pmc/articles/PMC11393545/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A benzarone derivative inhibits EYA to suppress tumor growth in SHH medulloblastoma
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1158/0008-5472.CAN-22-3784

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    ncbi.nlm.nih.gov/pmc/articles/PMC10948029/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MC4R Variants Modulate α-MSH and Setmelanotide Induced Cellular Signaling at Multiple Levels
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1210/clinem/dgae210

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    ncbi.nlm.nih.gov/pmc/articles/PMC11403317/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Drug Discovery Pipeline for MAPK/ERK Pathway Inhibitors in Caenorhabditis elegans
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1158/2767-9764.CRC-24-0221

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    ncbi.nlm.nih.gov/pmc/articles/PMC11409438/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anabolic deficits and divergent unfolded protein response underlie skeletal and cardiac muscle growth impairments in the Yoshida hepatoma tumor model of cancer cachexia
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.14814/phy2.70044

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    ncbi.nlm.nih.gov/pmc/articles/PMC11410559/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fidgetin-like 2 depletion enhances cell migration by regulating GEF-H1, RhoA, and FAK
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.bpj.2022.12.018

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    ncbi.nlm.nih.gov/pmc/articles/PMC10541466/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Probing Gag-Env dynamics at HIV-1 assembly sites using live-cell microscopy
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1128/jvi.00649-24

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    ncbi.nlm.nih.gov/pmc/articles/PMC11406925/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simple and highly specific targeting of resident microglia with adeno-associated virus
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.isci.2024.110706

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    ncbi.nlm.nih.gov/pmc/articles/PMC11407971/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosomal TBK1 responds to amino acid availability to relieve Rab7-dependent mTORC1 inhibition
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1038/s44318-024-00180-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC11405869/
  13. elifesciences.org elifesciences.org
    Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.7554/eLife.92774

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    elifesciences.org/articles/92774
  14. www.sciencedirect.com www.sciencedirect.com
    Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.ccell.2024.08.018

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    sciencedirect.com/science/article/pii/S1535610824003179
  15. www.sciencedirect.com www.sciencedirect.com
    A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.cell.2024.08.045

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    sciencedirect.com/science/article/pii/S0092867424009747
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1038/s41417-024-00809-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11405271/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.7150/thno.93879

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    ncbi.nlm.nih.gov/pmc/articles/PMC11388069/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of the RGD motif from the penton base in oncolytic adenoviruses enhances antitumor efficacy of combined CAR T cell therapy
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.omton.2024.200863

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    ncbi.nlm.nih.gov/pmc/articles/PMC11406095/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unlocking the Secrets of Adipose Tissue: How an Obesity-Associated Secretome Promotes Osteoblast Dedifferentiation via TGF-β1 Signaling, Paving the Path to an Adipogenic Phenotype
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.3390/cells13171418

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    ncbi.nlm.nih.gov/pmc/articles/PMC11394205/
  20. www.sciencedirect.com www.sciencedirect.com
    DDI2 protease controls embryonic development and inflammation via TCF11/NRF1
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.isci.2024.110893

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    sciencedirect.com/science/article/pii/S2589004224021187
  21. www.sciencedirect.com www.sciencedirect.com
    RNA-modifying enzyme Alkbh8 is involved in mouse embryonic development
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.isci.2024.110777

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    sciencedirect.com/science/article/pii/S2589004224020029
  22. www.sciencedirect.com www.sciencedirect.com
    IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.isci.2024.110767

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    sciencedirect.com/science/article/pii/S2589004224019928
  23. www.sciencedirect.com www.sciencedirect.com
    β-chitosan attenuates hepatic macrophage-driven inflammation and reverses aging-related cognitive impairment
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.isci.2024.110766

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    sciencedirect.com/science/article/pii/S2589004224019916
  24. www.sciencedirect.com www.sciencedirect.com
    Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.isci.2024.110701

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    sciencedirect.com/science/article/pii/S2589004224019266
  25. www.sciencedirect.com www.sciencedirect.com
    Group X phospholipase A2 links colonic lipid homeostasis to systemic metabolism via host-microbiota interaction
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.celrep.2024.114752

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    sciencedirect.com/science/article/pii/S2211124724011033
  26. www.sciencedirect.com www.sciencedirect.com
    Natural Linoleic Acid from Marine Fungus Eutypella sp. F0219 Blocks KEAP1/NRF2 Interaction and Ameliorates MASLD by Targeting FABP4
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.freeradbiomed.2024.09.019

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    sciencedirect.com/science/article/pii/S089158492400666X
  27. www.sciencedirect.com www.sciencedirect.com
    Lysosome-related organelle integrity suppresses TIR-1 aggregation to restrain toxic propagation of p38 innate immunity
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.celrep.2024.114674

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    sciencedirect.com/science/article/pii/S2211124724010258
  28. www.sciencedirect.com www.sciencedirect.com
    Intestinal immunity in C. elegans is activated by pathogen effector-triggered aggregation of the guard protein TIR-1 on lysosome-related organelles
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1016/j.immuni.2024.08.013

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    sciencedirect.com/science/article/pii/S1074761324004126
  29. www.sciencedirect.com www.sciencedirect.com
    Whole abdominal pencil beam scanned proton FLASH increases acute lethality
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.ijrobp.2024.09.006

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    sciencedirect.com/science/article/pii/S0360301624033273
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fentanyl depression of respiration: Comparison with heroin and morphine
    2
    1. scibot 25 Sep 2024
      RRID:SCR_013726

      DOI: 10.1111/bph.14860

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    2. scibot 25 Sep 2024
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      DOI: 10.1111/bph.14860

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    ncbi.nlm.nih.gov/pmc/articles/PMC6989952/
  31. www.embopress.org www.embopress.org
    Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA
    2
    1. scibot 25 Sep 2024
      SCR_002798

      DOI: 10.15252/embj.2019103654

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      RRID:SCR_002285

      DOI: 10.15252/embj.2019103654

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    embopress.org/doi/abs/10.15252/embj.2019103654
  32. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:SCR_000306

      DOI: 10.1111/bph.15131

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15131
  33. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:SCR_005375

      DOI: 10.1111/bph.15076

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15076
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility
    1
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      RRID:SCR_015382

      DOI: 10.7554/eLife.49717

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    ncbi.nlm.nih.gov/pmc/articles/PMC7007222/
  35. www.sciencedirect.com www.sciencedirect.com
    Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson’s Disease
    1
    1. scibot 25 Sep 2024
      RRID:SCR_005375

      DOI: 10.1016/j.cub.2019.11.079

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    sciencedirect.com/science/article/pii/S0960982219315817
  36. academic.oup.com academic.oup.com
    Transgenic overexpression of polysialyltransferase ST8SiaIV under the control of a neuron-specific promoter does not affect brain development but impairs exploratory behavior
    1
    1. scibot 25 Sep 2024
      RRID:SCR_002677

      DOI: 10.1093/glycob/cwz040

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    academic.oup.com/glycob/advance-article/doi/10.1093/glycob/cwz040/5506621
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    1. scibot 25 Sep 2024
      RRID:SCR_002798

      DOI: 10.1111/jnc.14709

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14709
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuroprotective effects of an engineered commensal bacterium in the 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine Parkinson disease mouse model via producing glucagon‐like peptide‐1
    1
    1. scibot 25 Sep 2024
      RRID:SCR_004812

      DOI: 10.1111/jnc.14694

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14694
  39. www.sciencedirect.com www.sciencedirect.com
    A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation
    1
    1. scibot 25 Sep 2024
      RRID:SCR_001622

      DOI: 10.1016/j.immuni.2019.02.004

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    sciencedirect.com/science/article/pii/S1074761319300494
  40. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Pathology of white matter integrity in three major white matter fasciculi: A post‐mortem study of schizophrenia and treatment status
    1
    1. scibot 25 Sep 2024
      RRID:SCR_005375

      DOI: 10.1111/bph.14612

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    Physiologically normal 5% O2 supports neuronal differentiation and resistance to inflammatory injury in neural stem cell cultures
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    Opposing Effects of Membrane-Anchored CX3CL1 on Amyloid and Tau Pathologies via the p38 MAPK Pathway
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    Interaction between the TBC1D24 TLDc domain and the KIBRA C2 domain is disrupted by two epilepsy-associated TBC1D24 missense variants
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    Age-associated temporal decline in butyrate-producing bacteria plays a key pathogenic role in the onset and progression of neuropathology and memory deficits in 3×Tg-AD mice
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    Rapid reorganization of serotonin projections and antidepressant response to 5-HT1A-biased agonist NLX-101 in fluoxetine-resistant cF1ko mice.
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    Comparative profiling of white matter development in the human and mouse brain reveals volumetric deficits and delayed myelination in Angelman syndrome
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    Uncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization
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    Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
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    Mitochondrial serine catabolism safeguards maintenance of the hematopoietic stem cell pool in homeostasis and injury
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    Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping
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    Protective Effect of Sulfur-Containing Heterocyclic Analogs Against Acrylamide-Induced Behavioral and Biochemical Alterations in Zebrafish
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    CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism
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    MiR-137-3p mechanisms of action and blood-brain barrier penetrating and neuron-targeting lipid nanoparticles deliver miR-137-3p for the treatment of Alzheimer's disease
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    RAD51 protects abasic sites to prevent replication fork breakage
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    GSK805 inhibits alpha-smooth muscle expression and modulates liver inflammation without impairing the well-being of mice
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    Chronic Lithium Treatment Alters NMDA and AMPA Receptor Synaptic Availability and Dendritic Spine Organization in the Rat Hippocampus
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    CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
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    Multiple guidance mechanisms control axon growth to generate precise T-shaped bifurcation during dorsal funiculus development in the spinal cord
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    Patient-derived tumor organoids mimic treatment-induced DNA damage response in glioblastoma
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    TRIM24 upregulates ORM2 to alleviate abnormal lipid metabolism, inflammation, and oxidative stress in mice with obstructive sleep apnea syndrome & metabolic dysfunction-associated steatotic liver disease
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    Camu-camu decreases hepatic steatosis and liver injury markers in overweight, hypertriglyceridemic individuals: A randomized crossover trial
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    Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females
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    Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion
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    Concurrent RB1 Loss and BRCA Deficiency Predicts Enhanced Immunologic Response and Long-term Survival in Tubo-ovarian High-grade Serous Carcinoma
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    Epithelial organoid supports resident memory CD8 T cell differentiation
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    Negative feedback control of hypothalamic feeding circuits by the taste of food
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    Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes
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    Protocol for transducing human primary epithelial prostate cells and patient-derived organoids with high efficiency
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    Multiple layers of diversity govern the cell type specificity of GABAergic input received by mouse subicular pyramidal neurons
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    Dysfunctional BTN3A together with deregulated immune checkpoints and type I/II IFN dictate defective interplay between pDCs and γδ T cells in melanoma patients, which impacts clinical outcomes
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    Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer
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    BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer
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    Protocol for in vivo nucleic acid delivery utilizing the rolling microneedle electrode array
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    Different Proteomic Profiles Regarding Antihypertensive Therapy in Preeclampsia Pregnant
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    "Expression and prognostic relevance of PD-1, PD-L1 and CTLA-4 immune checkpoints in adrenocortical carcinoma"
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    Paired organoids from primary gastric cancer and lymphatic metastasis are useful for personalized medicine
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    Crucial role for sensory nerves and Na/H exchanger inhibition in dapagliflozin and empagliflozin-induced arterial relaxation
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    The C-terminus of Rad is required for membrane localization and L-type calcium channel regulation
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    Taste cells expressing Ionotropic Receptor 94e reciprocally impact feeding and egg laying in Drosophila
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    OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
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    p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator
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    Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy
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    Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks
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    BDNF-dependent nano-organization of Neogenin and the WAVE Regulatory Complex promotes actin remodelling in dendritic spines
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    Functional genomic analysis of genes important for Candida albicans fitness in diverse environmental conditions
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    An actomyosin network organizes niche morphology and responds to feedback from recruited stem cells
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    PKD1 gene mutation and ultrasonographic characterization in cats with renal cysts
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    Glucagon infusion alters the circulating metabolome and urine amino acid excretion in dogs
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    Smooth muscle electromyography for detecting major alterations in the estrus cycle in rats
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    Amitriptyline and cholecalciferol amend hippocampal histological structure and myelination during stress in Wistar rats via regulating miR200/BMP4/Olig-2 signaling
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    Structural requirements for activity of Mind bomb1 in Notch signaling
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    Oligodendrocyte precursor cell-derived exosomes combined with cell therapy promote clinical recovery by immunomodulation and gliosis attenuation
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    Sphingosine-1 phosphate receptor 1 (S1PR1) expression maintains stemness of acute myeloid leukemia stem cells
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    Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism
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    A molecular pathway for cancer cachexia-induced muscle atrophy revealed at single-nucleus resolution
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    Small GTPase ActIvitY ANalyzing (SAIYAN) system: A method to detect GTPase activation in living cells
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    Regulatory Role and Cytoprotective Effects of Exogenous Recombinant SELENOM under Ischemia-like Conditions and Glutamate Excitotoxicity in Cortical Cells In Vitro
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    Age-, region-, and day/night-related variation of the chloride reversal potential in the rat suprachiasmatic nucleus
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