651 Matching Annotations
  1. Apr 2024
  2. www.biorxiv.org www.biorxiv.org
    Neural ensembles that encode affective mechanical and heat pain in mouse spinal cord
    1
    1. scibot 02 Apr 2024
      Gal-Cre mouse strain

      DOI: 10.1101/2024.02.05.578816

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    biorxiv.org/content/10.1101/2024.02.05.578816v1
  3. www.mdpi.com www.mdpi.com
    Absence of the Klotho Function Causes Cornea Degeneration with Specific Features Resembling Fuchs Endothelial Corneal Dystrophy and Bullous Keratopathy
    1
    1. scibot 02 Apr 2024
      Klotho null mutant mice with genetic backgrounds on C57BL/6J

      DOI: 10.3390/biology13030133

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    mdpi.com/2079-7737/13/3/133
  4. www.nature.com www.nature.com
    Dendritic mGluR2 and perisomatic Kv3 signaling regulate dendritic computation of mouse starburst amacrine cells
    1
    1. scibot 02 Apr 2024
      Drd4–GFP mice

      DOI: 10.1038/s41467-024-46234-7

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    nature.com/articles/s41467-024-46234-7
  5. www.biorxiv.org www.biorxiv.org
    Khdc3 Regulates Metabolism Across Generations in a DNA-Independent Manner
    1
    1. scibot 02 Apr 2024
      MMRRC

      DOI: 10.1101/2024.02.27.582278

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    biorxiv.org/content/10.1101/2024.02.27.582278v1
  6. www.science.org www.science.org
    Genetic determinants of blood pressure and heart rate identified through ENU-induced mutagenesis with automated meiotic mapping
    1
    1. scibot 01 Apr 2024
      MMRRC

      DOI: 10.1126/sciadv.adj9797

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    science.org/doi/10.1126/sciadv.adj9797
  7. www.biorxiv.org www.biorxiv.org
    The Updated Mouse Universal Genotyping Array Bioinformatic Pipeline Improves Genetic QC in Laboratory Mice
    1
    1. scibot 01 Apr 2024
      MMRRC

      DOI: 10.1101/2024.02.29.582794

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    biorxiv.org/content/10.1101/2024.02.29.582794v1
  8. Mar 2024
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Activation of the IKK2-NF𝜅B pathway in VSMCs inhibits calcified vascular stiffness in CKD
    1
    1. scibot 31 Mar 2024

      DOI: 10.1172/jci.insight.174977

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    pmc.ncbi.nlm.nih.gov/articles/PMC11128211/
  10. www.biorxiv.org www.biorxiv.org
    Nucleobindin-1 (Nucb1) disruption affects feeding, metabolism, and glucose homeostasis in mice in an age-, sex-, diet- and light cycle-dependent manner
    1
    1. scibot 31 Mar 2024
      MMRRC

      DOI: 10.1101/2024.03.07.584005

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    biorxiv.org/content/10.1101/2024.03.07.584005v2
  11. www.nature.com www.nature.com
    piRNA loading triggers MIWI translocation from the intermitochondrial cement to chromatoid body during mouse spermatogenesis
    1
    1. scibot 31 Mar 2024
      Miwi knockout mice

      DOI: 10.1038/s41467-024-46664-3

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    nature.com/articles/s41467-024-46664-3
  12. content.iospress.com content.iospress.com
    Early Mitochondrial Defects in the 5xFAD Mouse Model of Alzheimer’s Disease
    1
    1. scibot 28 Mar 2024
      5xFAD

      DOI: 10.3233/JAD-220884

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    content.iospress.com/articles/journal-of-alzheimers-disease/jad220884
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of Drug Resistance in Dengue Virus
    1
    1. scibot 20 Mar 2024
      MMRRC

      DOI: 10.1128/mBio.01960-15

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC4701834/
  14. Jan 2024
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact
    1
    1. scibot 21 Jan 2024
      RRID:SCR_002953

      DOI: 10.1101/2024.01.15.575636

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    pmc.ncbi.nlm.nih.gov/articles/PMC10827057/
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endosteal stem cells at the bone-blood interface: A double-edged sword for rapid bone formation
    1
    1. scibot 19 Jan 2024
      MMRRC

      DOI: 10.1002/bies.202300173

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    onlinelibrary.wiley.com/doi/full/10.1002/bies.202300173
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Direct interrogation of context-dependent GPCR activity with a universal biosensor platform
    1
    1. scibot 17 Jan 2024
      MMRRC

      DOI: 10.1101/2024.01.02.573921

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

      Curator: @bandrow

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    pmc.ncbi.nlm.nih.gov/articles/PMC10802303/
  18. www.biorxiv.org www.biorxiv.org
    Liver cancer initiation is dependent on metabolic zonation but decoupled from premalignant clonal expansion
    1
    1. scibot 17 Jan 2024
      Arid2fl/fl mice

      DOI: 10.1101/2024.01.10.575013

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

      Curator: @bandrow

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    biorxiv.org/content/10.1101/2024.01.10.575013v1
  19. www.sciencedirect.com www.sciencedirect.com
    Anatomy, physiological features, genetics and genetic alterations, breeding and strain differences relevant to the choice of the model—Impact of 3Rs
    1
    1. scibot 04 Jan 2024
      MMRRC

      DOI: 10.1016/B978-0-12-821180-9.00009-X

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    sciencedirect.com/science/article/pii/B978012821180900009X
  20. www.sciencedirect.com www.sciencedirect.com
    Modulation of the cell membrane lipid milieu by peroxisomal β-oxidation induces Rho1 signaling to trigger inflammatory responses
    1
    1. scibot 04 Jan 2024
      Bone marrow derived macrophages from Sw129-Pxmp3tm1Plf-/-

      DOI: 10.1016/j.celrep.2022.110433

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    sciencedirect.com/science/article/pii/S2211124722001607
  21. link.springer.com link.springer.com
    Abstracts of the 18th Transgenic Technology Meeting (TT2023)
    1
    1. scibot 03 Jan 2024
      MMRRC

      DOI: 10.1007/s11248-023-00372-8

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    link.springer.com/article/10.1007/s11248-023-00372-8
  22. www.nature.com www.nature.com
    The contribution of maternal oral, vaginal, and gut microbiota to the developing offspring gut
    1
    1. scibot 03 Jan 2024
      Mutant Mouse Resource and Research Center

      DOI: 10.1038/s41598-023-40703-7

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    nature.com/articles/s41598-023-40703-7
  23. www.jci.org www.jci.org
    A TRPV4-dependent neuro-immune axis in the spinal cord promotes neuropathic pain
    1
    1. scibot 03 Jan 2024
      Trpv4eGFP

      DOI: 10.1172/JCI161507

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

      Curator: @bandrow

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    jci.org/articles/view/161507
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effects of reversible SERCA inhibition on catecholamine exocytosis and intracellular [Ca2+] signaling in chromaffin cells from normotensive Wistar Kyoto rats and spontaneously hypertensive rats
    1
    1. scibot 03 Jan 2024
      MMRRC

      DOI: 10.1007/s00424-023-02859-z

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

      Curator: @bandrow

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    pmc.ncbi.nlm.nih.gov/articles/PMC10758371/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic influences on motor learning and superperformance mutants revealed by random mutational survey of mouse locomotion
    1
    1. scibot 03 Jan 2024
      Mutant Mouse Resource & Research Centers (https://www.mmrrc.org/).

      DOI: 10.1101/2023.06.28.546756

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    ncbi.nlm.nih.gov/pmc/articles/PMC10327015/
  26. www.nature.com www.nature.com
    Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity
    1
    1. scibot 03 Jan 2024
      MMRRC

      DOI: 10.1038/s42003-023-04974-0

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    nature.com/articles/s42003-023-04974-0
  27. www.jci.org www.jci.org
    Hypertriglyceridemia in <i>Apoa5<sup>–/–</sup></i> mice results from reduced amounts of lipoprotein lipase in the capillary lumen
    1
    1. scibot 03 Jan 2024
      Apoa5

      DOI: 10.1172/JCI172600

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    jci.org/articles/view/172600
  28. www.mdpi.com www.mdpi.com
    Sexual Dimorphism of the Mouse Plasma Metabolome Is Associated with Phenotypes of 30 Gene Knockout Lines
    1
    1. scibot 03 Jan 2024
      MMRRC

      DOI: 10.3390/metabo13080947

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    mdpi.com/2218-1989/13/8/947
  29. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Genotyping Protocols for Genetically Engineered Mice
    1
    1. scibot 03 Jan 2024
      Mice

      DOI: 10.1002/cpz1.929

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    currentprotocols.onlinelibrary.wiley.com/doi/full/10.1002/cpz1.929
  30. journals.plos.org journals.plos.org
    GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans
    1
    1. scibot 03 Jan 2024
      Cytip tm1a

      DOI: 10.1371/journal.pgen.1010666

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    journals.plos.org/plosgenetics/article
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cre-recombinase systems for induction of neuron-specific knockout models: a guide for biomedical researchers
    1
    1. scibot 03 Jan 2024
      MMRRC

      DOI: 10.4103/1673-5374.346541

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    ncbi.nlm.nih.gov/pmc/articles/PMC9396489/
  32. www.biorxiv.org www.biorxiv.org
    Chimeric Antigen Receptor Macrophages Target and Resorb Amyloid Plaques in a Mouse Model of Alzheimer’s Disease
    1
    1. scibot 03 Jan 2024
      MMRRC

      DOI: 10.1101/2023.04.28.538637

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    biorxiv.org/content/10.1101/2023.04.28.538637v2
  33. www.nature.com www.nature.com
    Sphingosine-1-phosphate suppresses GLUT activity through PP2A and counteracts hyperglycemia in diabetic red blood cells
    1
    1. scibot 03 Jan 2024
      Mfsd2b

      DOI: 10.1038/s41467-023-44109-x

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    nature.com/articles/s41467-023-44109-x
  34. www.mdpi.com www.mdpi.com
    Fatal Epileptic Seizures in Mice Having Compromised Glutathione and Ascorbic Acid Biosynthesis
    1
    1. scibot 03 Jan 2024
      MMRRC

      DOI: 10.3390/antiox12020448

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

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    mdpi.com/2076-3921/12/2/448
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intranasal immunization with an RBD-hemagglutinin fusion protein harnesses preexisting immunity to enhance antigen-specific responses
    1
    1. scibot 03 Jan 2024
      (IgA–/–) BALB/c mice

      DOI: 10.1172/JCI166827

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    ncbi.nlm.nih.gov/pmc/articles/PMC10688985/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Studying the Roles of the Renin–Angiotensin System in Accelerating the Disease of High-Fat-Diet-Induced Diabetic Nephropathy in a db/db and ACE2 Double-Gene-Knockout Mouse Model
    1
    1. scibot 03 Jan 2024
      129S5-Ace2tm1/Lex/Mmcd

      DOI: 10.3390/ijms25010329

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    pmc.ncbi.nlm.nih.gov/articles/PMC10779113/
  37. www.biorxiv.org www.biorxiv.org
    Astrocyte-to-microglia communication via Sema4B-Plexin-B2 modulates injury-induced reactivity of microglia
    1
    1. scibot 03 Jan 2024
      Sema4B+/− mutant mice

      DOI: 10.1101/2023.11.07.565986

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    biorxiv.org/content/10.1101/2023.11.07.565986v1
  38. www.biorxiv.org www.biorxiv.org
    Activation of the IKK2-NFκB pathway in VSMCs inhibits calcified vascular stiffness in CKD by reducing the secretion of calcifying extracellular vesicles
    1
    1. scibot 03 Jan 2024
      MMRRC

      DOI: 10.1101/2023.07.11.548621

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    biorxiv.org/content/10.1101/2023.07.11.548621v1
  39. www.sciencedirect.com www.sciencedirect.com
    A precisely humanized FCRN transgenic mouse for preclinical pharmacokinetics studies
    1
    1. scibot 03 Jan 2024
      MMRRC

      DOI: 10.1016/j.bcp.2023.115470

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    sciencedirect.com/science/article/pii/S0006295223000618
  40. www.sciencedirect.com www.sciencedirect.com
    Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation
    1
    1. scibot 03 Jan 2024
      MMRRC

      DOI: 10.1016/j.phrs.2023.106941

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    sciencedirect.com/science/article/pii/S1043661823002979
  41. www.nature.com www.nature.com
    Revealing concealed cardioprotection by platelet Mfsd2b-released S1P in human and murine myocardial infarction
    1
    1. scibot 02 Jan 2024
      Mfsd2b

      DOI: 10.1038/s41467-023-38069-5

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    nature.com/articles/s41467-023-38069-5
  42. 52.53.155.43 52.53.155.43
    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
    1
    1. scibot 02 Jan 2024
      Mfn1flox/flox and Mfn2flox/flox

      DOI: 10.1126/sciimmunol.abq2424

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    52.53.155.43/93ebbe5a83b6a28b0d01edad42fa81f437079176/sciimmunol.abq2424_sm-html.html
  43. www.sciencedirect.com www.sciencedirect.com
    Novel discovery of a lymphatic bridge connecting Schlemm's canal to limbal and conjunctival lymphatic pathway
    1
    1. scibot 02 Jan 2024
      MMRRC

      DOI: 10.1016/j.jtos.2023.05.009

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    sciencedirect.com/science/article/pii/S1542012423000514
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    New mouse models with hypomorphic SUMF1 variants mimic attenuated forms of multiple sulfatase deficiency
    1
    1. scibot 02 Jan 2024
      MMRRC

      DOI: 10.1002/jimd.12577

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    pmc.ncbi.nlm.nih.gov/articles/PMC10832386/
  45. www.nature.com www.nature.com
    The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease
    1
    1. scibot 02 Jan 2024
      C57BL/6 Pd-1h-/-

      DOI: 10.1038/s41467-023-39769-8

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  46. link.springer.com link.springer.com
    Mouse Models to Study Peroxisomal Functions and Disorders: Overview, Caveats, and Recommendations
    1
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      MMRRC

      DOI: 10.1007/978-1-0716-3048-8_34

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  47. www.biorxiv.org www.biorxiv.org
    Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Mice Consuming Alcohol Attenuates Glycolysis
    2
    1. scibot 02 Jan 2024
      AdoraA2-Cre

      DOI: 10.1101/2023.11.29.569312

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      Drd1a-Cre

      DOI: 10.1101/2023.11.29.569312

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    biorxiv.org/content/10.1101/2023.11.29.569312v1
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PGE2 potentiates Orai1-mediated calcium entry contributing to peripheral sensitization
    1
    1. scibot 02 Jan 2024
      Orai1 knockout

      DOI: 10.1523/JNEUROSCI.0329-23.2023

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    pmc.ncbi.nlm.nih.gov/articles/PMC10851687/
  49. www.biorxiv.org www.biorxiv.org
    BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice
    1
    1. scibot 02 Jan 2024
      5xFAD mice (C56BL/6J background)

      DOI: 10.1101/2023.08.03.551881

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  50. www.sciencedirect.com www.sciencedirect.com
    Neuronal deletion of nSMase2 reduces the production of Aβ and directly protects neurons
    1
    1. scibot 02 Jan 2024
      MMRRC

      DOI: 10.1016/j.nbd.2023.105987

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    sciencedirect.com/science/article/pii/S0969996123000013
  51. www.mdpi.com www.mdpi.com
    ACE2 and a Traditional Chinese Medicine Formula NRICM101 Could Alleviate the Inflammation and Pathogenic Process of Acute Lung Injury
    1
    1. scibot 02 Jan 2024
      B6;129S5-Ace2tm1Lex/Mmcd)

      DOI: 10.3390/medicina59091554

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  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ezh2-dependent methylation in oral epithelia promotes secondary palatogenesis
    1
    1. scibot 02 Jan 2024
      Grhl3Cre knock-in mouse line

      DOI: 10.1002/bdr2.2216

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    onlinelibrary.wiley.com/doi/full/10.1002/bdr2.2216
  53. www.biorxiv.org www.biorxiv.org
    Neural circuit models for evidence accumulation through choice-selective sequences
    1
    1. scibot 02 Jan 2024
      EY262Gsat, MMRRC-UCD)

      DOI: 10.1101/2023.09.01.555612

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    biorxiv.org/content/10.1101/2023.09.01.555612v3
  54. www.biorxiv.org www.biorxiv.org
    Effect size of delayed freezing, diurnal variation, and hindgut location on the mouse fecal microbiome relative to a standardized biological variable
    1
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      MMRRC

      DOI: 10.1101/2023.07.13.548851

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  55. www.mdpi.com www.mdpi.com
    Klotho Null Mutation Indirectly Leads to Age-Related Lacrimal Gland Degeneration in Mutant Mice
    1
    1. scibot 02 Jan 2024
      MRRC

      DOI: 10.3390/biology12101328

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  56. www.sciencedirect.com www.sciencedirect.com
    Distinct effects of cardiac mitochondrial calcium uniporter inactivation via EMRE deletion in the short and long term
    1
    1. scibot 02 Jan 2024
      Emreflox/flox

      DOI: 10.1016/j.yjmcc.2023.05.007

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    sciencedirect.com/science/article/pii/S0022282823000937
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Structural-functional properties of direct-pathway striatal neurons at early and chronic stages of dopamine denervation
    1
    1. scibot 02 Jan 2024
      BAC-drd1a-TdTomato

      DOI: 10.1111/ejn.16166

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    onlinelibrary.wiley.com/doi/full/10.1111/ejn.16166
  58. www.mdpi.com www.mdpi.com
    Low-Dose Chidamide Treatment Displays Sex-Specific Differences in the 3xTg-AD Mouse
    1
    1. scibot 02 Jan 2024
      triple-transgenic AD (3xTg-AD

      DOI: 10.3390/biom13091324

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    mdpi.com/2218-273X/13/9/1324
  59. www.biorxiv.org www.biorxiv.org
    SRRM2 splicing factor modulates cell fate in early development
    1
    1. scibot 02 Jan 2024
      MMRRC

      DOI: 10.1101/2023.12.15.571825

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  60. www.nature.com www.nature.com
    Topologically associating domain boundaries are required for normal genome function
    1
    1. scibot 02 Jan 2024
      made available through the Mutant Mouse Resource

      DOI: 10.1038/s42003-023-04819-w

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    nature.com/articles/s42003-023-04819-w
  61. link.springer.com link.springer.com
    TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models
    1
    1. scibot 02 Jan 2024
      Rbp4-Cre (GENSAT, MMRRC, #4367067

      DOI: 10.1007/s00401-023-02615-8

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  62. www.sciencedirect.com www.sciencedirect.com
    Illuminating the druggable genome: Pathways to progress
    1
    1. scibot 02 Jan 2024
      MMRRC

      DOI: 10.1016/j.drudis.2023.103805

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    sciencedirect.com/science/article/pii/S1359644623003215
  63. www.pnas.org www.pnas.org
    Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs
    1
    1. scibot 02 Jan 2024
      MMRRC

      DOI: 10.1073/pnas.2315282120

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    pnas.org/doi/abs/10.1073/pnas.2315282120
  64. esmed.org esmed.org
    Why Angiotensin II is a Poor Choice for Circulatory Support of Ventilated COVID-19 Patients Compared to Vasopressin
    1
    1. scibot 02 Jan 2024
      Repositories

      DOI: 3871

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    esmed.org/MRA/mra/article/view/3871
  65. www.biorxiv.org www.biorxiv.org
    FAM210B is dispensable for erythroid differentiation in adult mice
    1
    1. scibot 02 Jan 2024
      C57BL6N/6N- Atm1BrdFam210btm1b(KOMP)/Mbp /MbpMmucd

      DOI: 10.1101/2023.09.26.559581

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  66. www.sciencedirect.com www.sciencedirect.com
    Illuminating the understudied GPCR-ome
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    1. scibot 02 Jan 2024
      MMRRC

      DOI: 10.1016/j.drudis.2023.103848

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    sciencedirect.com/science/article/pii/S1359644623003641
  67. www.sciencedirect.com www.sciencedirect.com
    CCN1 expression is regulated by mechanical stimuli in tendons
    1
    1. scibot 02 Jan 2024
      CCN1:eGFP reporter mice

      DOI: 10.1016/j.bbrc.2023.04.058

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    sciencedirect.com/science/article/pii/S0006291X23004734
  68. www.sciencedirect.com www.sciencedirect.com
    PANEL 3: Otitis media animal models, cell culture, tissue regeneration & pathophysiology
    1
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      MMRRC

      DOI: 10.1016/j.ijporl.2023.111814

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    sciencedirect.com/science/article/pii/S0165587623003816
  69. link.springer.com link.springer.com
    Web-Based Resources to Investigate Protease Function
    1
    1. scibot 02 Jan 2024
      https://www.mmrrc.org/

      DOI: 10.1007/978-1-0716-3589-6_1

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  70. www.mdpi.com www.mdpi.com
    Standardized Complex Gut Microbiomes Influence Fetal Growth, Food Intake, and Adult Body Weight in Outbred Mice
    1
    1. scibot 02 Jan 2024
      Six CD1GM1 and eight CD1GM4

      DOI: 10.3390/microorganisms11020484

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  71. www.sciencedirect.com www.sciencedirect.com
    Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aβ immunotherapy
    1
    1. scibot 02 Jan 2024
      B6/129-Psen1 Tg(APPSwe,tauP301L)1Lfa/Mmjax, APPswePS1MAPT

      DOI: 10.1016/j.nbas.2023.100066

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    sciencedirect.com/science/article/pii/S2589958923000038
  72. Dec 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroscience of Disease: Human KCNQ5 de novo mutations underlie epilepsy and intellectual disability
    1
    1. scibot 31 Dec 2023
      MMRRC

      DOI: 10.1152/jn.00509.2021

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    ncbi.nlm.nih.gov/pmc/articles/PMC9236882/
  74. www.biorxiv.org www.biorxiv.org
    A conditional null allele of Dync1h1 enables targeted analyses of dynein roles in neuronal length sensing and neurological disorders
    1
    1. scibot 31 Dec 2023
      https://www.mmrrc.org/

      DOI: 10.1101/2022.02.20.481176

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    biorxiv.org/content/10.1101/2022.02.20.481176v1
  75. content.iospress.com content.iospress.com
    The Combined Effects of Amyloidosis and Serotonin Deficiency by Tryptophan Hydroxylase-2 Knockout Impacts Viability of the APP/PS1 Mouse Model of Alzheimer’s Disease
    1
    1. scibot 30 Dec 2023
      PS1) ΔE9 transgenic mice.

      DOI: 10.3233/JAD-210581

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    content.iospress.com/articles/journal-of-alzheimers-disease/jad210581
  76. academic.oup.com academic.oup.com
    Centralizing neurofibromatosis experimental tool knowledge with the NF Research Tools Database
    1
    1. scibot 30 Dec 2023
      MMRRC

      DOI: 10.1093/database/baac045

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    academic.oup.com/database/article/doi/10.1093/database/baac045/6613566
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mouse mutagenesis and phenotyping to generate models of development and disease
    1
    1. scibot 30 Dec 2023
      www.mmrrc.org

      DOI: 10.1016/bs.ctdb.2022.02.012

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    pmc.ncbi.nlm.nih.gov/articles/PMC11275630/
  78. content.iospress.com content.iospress.com
    JOTROL, a Novel Formulation of Resveratrol, Shows Beneficial Effects in the 3xTg-AD Mouse Model
    1
    1. scibot 30 Dec 2023
      Mouse

      DOI: 10.3233/JAD-215370

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    content.iospress.com/articles/journal-of-alzheimers-disease/jad215370
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic Strategies to Study T Cell Development
    1
    1. scibot 30 Dec 2023
      https://www.mmrrc.org

      DOI: 10.1007/978-1-0716-2740-2_6

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    pmc.ncbi.nlm.nih.gov/articles/PMC10803070/
  80. www.biorxiv.org www.biorxiv.org
    A HUMANIZED FCRN TRANSGENIC MOUSE FOR PRECLINICAL PHARMACOKINETICS STUDIES
    1
    1. scibot 30 Dec 2023
      MMRRC

      DOI: 10.1101/2022.10.24.513622

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    biorxiv.org/content/10.1101/2022.10.24.513622v1
  81. www.jneurosci.org www.jneurosci.org
    T-Type Ca2+ Channels Boost Neurotransmission in Mammalian Cone Photoreceptors
    1
    1. scibot 30 Dec 2023
      Tg(Rac3-EGFP)JZ58Gsat/Mmcd

      DOI: 10.1523/JNEUROSCI.1878-21.2022

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    jneurosci.org/content/42/33/6325
  82. Oct 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of WNK3 kinase signaling reduces brain damage and accelerates neurological recovery after stroke
    1
    1. scibot 03 Oct 2023
      mmrrc.ucdavis.edu

      DOI: 10.1161/STROKEAHA.115.008939

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    ncbi.nlm.nih.gov/pmc/articles/PMC4643659/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke
    1
    1. scibot 03 Oct 2023
      WNK3

      DOI: 10.1177/0271678X16631561

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    ncbi.nlm.nih.gov/pmc/articles/PMC5381450/
  85. Jun 2023
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by Angiotensin-(1-7)
    1
    1. scibot 06 Jun 2023
      Subjects

      DOI: 10.1042/CS20220904

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    pmc.ncbi.nlm.nih.gov/articles/PMC10881191/
  87. May 2023
  88. www.mdpi.com www.mdpi.com
    [124I]IBETA: A New A&beta; Plaque Positron Emission Tomography Imaging Agent for Alzheimer&rsquo;s Disease
    1
    1. scibot 06 May 2023
      MMRRC

      DOI: 10.3390/molecules27144552

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    mdpi.com/1420-3049/27/14/4552/htm
  89. pubs.acs.org pubs.acs.org
    Novologue Therapy Requires Heat Shock Protein 70 and Thioredoxin-Interacting Protein to Improve Mitochondrial Bioenergetics and Decrease Mitophagy in Diabetic Sensory Neurons
    1
    1. scibot 06 May 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1021/acschemneuro.1c00340

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    pubs.acs.org/doi/10.1021/acschemneuro.1c00340
  90. ejnmmires.springeropen.com ejnmmires.springeropen.com
    [18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice
    1
    1. scibot 06 May 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1186/s13550-022-00914-x

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    ejnmmires.springeropen.com/articles/10.1186/s13550-022-00914-x
  91. www.mdpi.com www.mdpi.com
    Differential Responses to Sigma-1 or Sigma-2 Receptor Ablation in Adiposity, Fat Oxidation, and Sexual Dimorphism
    1
    1. scibot 06 May 2023
      MMRRC

      DOI: 10.3390/ijms231810846

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    mdpi.com/1422-0067/23/18/10846/htm
  92. asbmr.onlinelibrary.wiley.com asbmr.onlinelibrary.wiley.com
    Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice
    1
    1. scibot 05 May 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1002/jbmr.4323

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    asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.4323
  93. www.embopress.org www.embopress.org
    Aire-dependent transcripts escape Raver2-induced splice-event inclusion in the thymic epithelium
    1
    1. scibot 05 May 2023
      https://www.mmrrc.org

      DOI: 10.15252/embr.202153576

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    embopress.org/doi/full/10.15252/embr.202153576
  94. www.embopress.org www.embopress.org
    PKM2-TMEM33 axis regulates lipid homeostasis in cancer cells by controlling SCAP stability
    1
    1. scibot 05 May 2023
      TMEM33+/-

      DOI: 10.15252/embj.2021108065

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    embopress.org/doi/full/10.15252/embj.2021108065
  95. anatomypubs.onlinelibrary.wiley.com anatomypubs.onlinelibrary.wiley.com
    Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and non-canonical Wnt signaling
    1
    1. scibot 05 May 2023
      B6; 129S5-GPC4tm1LexMmcd

      DOI: 10.1002/dvdy.533

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    anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/dvdy.533
  96. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    5-HT3Rs Maintain Hippocampal LTP in a CB1R-GABAA-Dependent Manner for Spatial Memory
    1
    1. scibot 05 May 2023
      STOCK Tg [Htr3a-EGFP] 1Gsat/Mmnc)

      DOI: 10.1111/bph.15793

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.15793
  97. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Ablation of PDE4B protects from Pseudomonas aeruginosa-induced acute lung injury in mice by ameliorating the cytostorm and associated hypothermia
    1
    1. scibot 05 May 2023
      MMRRC

      DOI: 10.1096/fj.202100495R

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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202100495R
  98. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oligodendrogenesis is a key process for cognitive performance improvement induced by voluntary physical activity
    1
    1. scibot 05 May 2023
      Sox10-GFP

      DOI: 10.1002/glia.24155

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    onlinelibrary.wiley.com/doi/full/10.1002/glia.24155
  99. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Genetic deletion of Cyp4f18 disrupts the omega-3 epoxidation pathway and results in psoriasis-like dermatitis
    1
    1. scibot 05 May 2023
      Cyp4f18

      DOI: 10.1096/fj.202200982R

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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202200982R
  100. Apr 2023
  101. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Erythroferrone contributes to iron mobilization for embryo erythropoiesis in iron-deficient mouse pregnancies
    1
    1. scibot 29 Apr 2023
      Erfe KO/Fam123b KO

      DOI: 10.1002/ajh.26680

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    onlinelibrary.wiley.com/doi/full/10.1002/ajh.26680
  102. www.biorxiv.org www.biorxiv.org
    Multiple dynamic interactions from basal ganglia direct and indirect pathways mediate action selection
    1
    1. scibot 11 Apr 2023
      MMRRC

      DOI: 10.1101/2023.03.20.533567

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    biorxiv.org/content/10.1101/2023.03.20.533567v3
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Striatal Balancing Act in Drug Addiction: Distinct Roles of Direct and Indirect Pathway Medium Spiny Neurons
    1
    1. scibot 04 Apr 2023
      MMRRC

      DOI: 10.3389/fnana.2011.00041

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    ncbi.nlm.nih.gov/pmc/articles/PMC3140647/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic quality assurance and genetic monitoring of laboratory mice and rats: FELASA Working Group Report
    1
    1. scibot 04 Apr 2023
      MMRRC

      DOI: 10.1177/0023677219867719

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    ncbi.nlm.nih.gov/pmc/articles/PMC7160752/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species
    1
    1. scibot 04 Apr 2023
      Mutant Mouse Resource and Research Centers

      DOI: 10.1093/nar/gkz997

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    ncbi.nlm.nih.gov/pmc/articles/PMC7056945/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling Genetic Susceptibility to Disease
    1
    1. scibot 04 Apr 2023
      Mutant Mouse Resource and Research Centers

      DOI: 10.1016/B978-0-12-801238-3.95609-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC7152220/
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biology and Diseases of Mice
    1
    1. scibot 04 Apr 2023
      Mutant Mouse Regional Resource Centers

      DOI: 10.1016/B978-0-12-409527-4.00003-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC7150197/
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    From Mice to Humans
    1
    1. scibot 04 Apr 2023
      Mouse Mutant Resource Regional Centres

      DOI: 10.1007/s11892-012-0323-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC3488608/
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tet-Transgenic Rodents: a comprehensive, up-to date database
    1
    1. scibot 04 Apr 2023
      MMRRC

      DOI: 10.1007/s11248-012-9660-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC3591533/
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    33rd international mammalian genome conference: meeting highlights
    1
    1. scibot 04 Apr 2023
      MMRRC

      DOI: 10.1007/s00335-020-09830-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC7087741/
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    27th International Mammalian Genome Conference meeting report
    1
    1. scibot 04 Apr 2023
      MMRRC

      DOI: 10.1007/s00335-014-9513-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC7088217/
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data
    1
    1. scibot 04 Apr 2023
      Mutant Mouse Regional Resource Centers

      DOI: 10.1007/s00335-012-9421-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC3463787/
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Critical Roles of Dual-Specificity Phosphatases in Neuronal Proteostasis and Neurological Diseases
    1
    1. scibot 04 Apr 2023
      Mutant Mouse Resource and Research Centers

      DOI: 10.3390/ijms18091963

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    ncbi.nlm.nih.gov/pmc/articles/PMC5618612/
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Methodologies and Challenges for CRISPR/Cas9 Mediated Genome Editing of the Mammalian Brain
    1
    1. scibot 04 Apr 2023
      MMRRC

      DOI: 10.3389/fgeed.2020.602970

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    ncbi.nlm.nih.gov/pmc/articles/PMC8525404/
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mammalian gene function resource: the international knockout mouse consortium
    1
    1. scibot 04 Apr 2023
      MMRRC

      DOI: 10.1007/s00335-012-9422-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC3463800/
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A resource of vectors and ES cells for targeted deletion of microRNAs in mice
    1
    1. scibot 04 Apr 2023
      MMRRC

      DOI: 10.1038/nbt.1929

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    ncbi.nlm.nih.gov/pmc/articles/PMC3242032/
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryopreservation of mouse resources
    1
    1. scibot 04 Apr 2023
      Mutant Mouse Regional Resource Centers

      DOI: 10.1186/s42826-020-00066-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC7495967/
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mouse genetics toolkit: revealing function and mechanism
    1
    1. scibot 04 Apr 2023
      Mutant Mouse Regional Resource Centers

      DOI: 10.1186/gb-2011-12-6-224

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    ncbi.nlm.nih.gov/pmc/articles/PMC3218837/
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CreZOO—the European virtual repository of Cre and other targeted conditional driver strains
    1
    1. scibot 04 Apr 2023
      MMRRC

      DOI: 10.1093/database/bas029

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    ncbi.nlm.nih.gov/pmc/articles/PMC3381224/
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Mouse Universal Genotyping Array: From Substrains to Subspecies
    1
    1. scibot 04 Apr 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1534/g3.115.022087

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    ncbi.nlm.nih.gov/pmc/articles/PMC4751547/
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Saturation mutagenesis defines novel mouse models of severe spine deformity
    1
    1. scibot 04 Apr 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1242/dmm.048901

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    ncbi.nlm.nih.gov/pmc/articles/PMC8246263/
  122. Mar 2023
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peroxisomes Regulate Cellular Free Fatty Acids to Modulate Mast Cell TLR2, TLR4, and IgE-Mediated Activation
    1
    1. scibot 24 Mar 2023
      129S6.129-Pex2 tm1Plf /Mmmh

      DOI: 10.3389/fcell.2022.856243

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    ncbi.nlm.nih.gov/pmc/articles/PMC9215104/
  124. www.jneurosci.org www.jneurosci.org
    Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development
    1
    1. scibot 24 Mar 2023
      B6(Cg)-Cux2<tm1.1(cre)Mull>/Mmmh

      DOI: 10.1523/JNEUROSCI.0124-22.2022

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    jneurosci.org/content/42/19/3931
  125. journals.biologists.com journals.biologists.com
    Focal adhesion kinase-mediated signaling controls the onset of pancreatic cell differentiation
    1
    1. scibot 24 Mar 2023
      Fak-floxed

      DOI: 10.1242/dev.200761

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    journals.biologists.com/dev/article/149/17/dev200761/276568/Focal-adhesion-kinase-mediated-signaling-controls
  126. www.biorxiv.org www.biorxiv.org
    Neuroinvasive flavivirus pathogenesis is restricted by host genetic factors in Collaborative Cross mice, independently of Oas1b
    1
    1. scibot 24 Mar 2023
      CC019-Oas1bdel

      DOI: 10.1101/2022.10.24.513634

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    biorxiv.org/content/10.1101/2022.10.24.513634v1
  127. www.nature.com www.nature.com
    3R measures in facilities for the production of genetically modified rodents
    1
    1. scibot 24 Mar 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1038/s41684-022-00978-1

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    nature.com/articles/s41684-022-00978-1
  128. www.science.org www.science.org
    The Candida albicans toxin candidalysin mediates distinct epithelial inflammatory responses through p38 and EGFR-ERK pathways
    1
    1. scibot 24 Mar 2023
      Fosfl/fl

      DOI: 10.1126/scisignal.abj6915

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    science.org/doi/10.1126/scisignal.abj6915
  129. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells
    1
    1. scibot 24 Mar 2023
      B6;129S7-Twist1fl/fl

      DOI: 10.1242/dev.200068

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    pmc.ncbi.nlm.nih.gov/articles/PMC9440756/
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A requirement for Krüppel Like Factor‐4 in the maintenance of endothelial cell quiescence
    1
    1. scibot 24 Mar 2023
      Klf4fl/wt

      DOI: 10.3389/fcell.2022.1003028

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    ncbi.nlm.nih.gov/pmc/articles/PMC9679496/
  131. journals.plos.org journals.plos.org
    Shp2 in uterine stromal cells critically regulates on time embryo implantation and stromal decidualization by multiple pathways during early pregnancy
    1
    1. scibot 24 Mar 2023
      Shp2flox/fox

      DOI: 10.1371/journal.pgen.1010018

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    journals.plos.org/plosgenetics/article
  132. www.nature.com www.nature.com
    Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis
    1
    1. scibot 24 Mar 2023
      Klf4(flox/flox)

      DOI: 10.1038/s41467-021-27499-8

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    nature.com/articles/s41467-021-27499-8
  133. www.nature.com www.nature.com
    FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation
    1
    1. scibot 23 Mar 2023
      MMRRC

      DOI: 10.1038/s41586-021-04144-4

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    nature.com/articles/s41586-021-04144-4
  134. aacrjournals.org aacrjournals.org
    Mice Deficient in the RNA-Binding Protein Zfp871 Are Prone to Early Death and Steatohepatitis in Part through the p53–Mdm2 Axis
    1
    1. scibot 23 Mar 2023
      Zfp871

      DOI: 10.1158/1541-7786.MCR-21-0239

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    aacrjournals.org/mcr/article/19/10/1751/665681/Mice-Deficient-in-the-RNA-Binding-Protein-Zfp871
  135. www.biorxiv.org www.biorxiv.org
    Dopaminergic axons track somatic signaling in behaving mice
    1
    1. scibot 23 Mar 2023
      MMRRC

      DOI: 10.1101/2022.06.20.496872

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    biorxiv.org/content/10.1101/2022.06.20.496872v1
  136. cgp.iiarjournals.org cgp.iiarjournals.org
    Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell Line
    1
    1. scibot 23 Mar 2023
      STOCK ptf1atm1(cre)Cvw

      DOI: 10.21873/cgp.20248

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    cgp.iiarjournals.org/content/18/2/133
  137. www.nature.com www.nature.com
    Dual roles of hexokinase 2 in shaping microglial function by gating glycolytic flux and mitochondrial activity
    1
    1. scibot 23 Mar 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1038/s42255-022-00707-5

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    nature.com/articles/s42255-022-00707-5
  138. www.biorxiv.org www.biorxiv.org
    Modulation of dLGN firing mode across multiple timescales is predicted by pupil size dynamics
    1
    1. scibot 23 Mar 2023
      B6.FVB(Cg)-Tg(Ntsr1-cre)GN220Gsat/Mmcd

      DOI: 10.1101/2021.04.30.442134

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    biorxiv.org/content/10.1101/2021.04.30.442134v2
  139. www.jci.org www.jci.org
    The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis
    1
    1. scibot 23 Mar 2023
      Slc39a8fl/+

      DOI: 10.1172/JCI157338

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    jci.org/articles/view/157338
  140. www.nature.com www.nature.com
    Revealing nanostructures in brain tissue via protein decrowding by iterative expansion microscopy
    1
    1. scibot 23 Mar 2023
      5xFAD

      DOI: 10.1038/s41551-022-00912-3

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    nature.com/articles/s41551-022-00912-3
  141. www.jci.org www.jci.org
    A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy
    1
    1. scibot 23 Mar 2023
      Piezo1-floxed

      DOI: 10.1172/JCI154611

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    jci.org/articles/view/154611
  142. link.springer.com link.springer.com
    Chemerin regulates normal angiogenesis and hypoxia-driven neovascularization
    1
    1. scibot 23 Mar 2023
      C57BL/6 N-Rarres2tm1(KOMP)Vlcg/MbpMmucd

      DOI: 10.1007/s10456-021-09818-1

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    link.springer.com/article/10.1007/s10456-021-09818-1
  143. link.springer.com link.springer.com
    Mouse Genome Informatics (MGI): latest news from MGD and GXD
    1
    1. scibot 23 Mar 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1007/s00335-021-09921-0

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    link.springer.com/article/10.1007/s00335-021-09921-0
  144. www.sciencedirect.com www.sciencedirect.com
    Reduced housing density improves statistical power of murine gut microbiota studies
    1
    1. scibot 23 Mar 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1016/j.celrep.2022.110783

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    sciencedirect.com/science/article/pii/S2211124722005502
  145. www.biorxiv.org www.biorxiv.org
    Modulating D1 rather than D2 receptor-expressing spiny-projection neurons corresponds to optimal antipsychotic effect
    2
    1. scibot 23 Mar 2023
      Adora2a (KG139) BAC

      DOI: 10.1101/2021.08.03.454992

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      RRIDCUR:Missing RRID:SCR_002953
    2. scibot 23 Mar 2023
      GENSAT Drd1a (FK150)

      DOI: 10.1101/2021.08.03.454992

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    biorxiv.org/content/10.1101/2021.08.03.454992v1
  146. link.springer.com link.springer.com
    A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes
    1
    1. scibot 23 Mar 2023
      B6.C-Tg(CMV-cre)1Cgn/Jas

      DOI: 10.1007/s00018-022-04546-1

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    link.springer.com/article/10.1007/s00018-022-04546-1
  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FoxA-dependent DNA demethylation initiates epigenetic control of cellular stability
    1
    1. scibot 23 Mar 2023
      MMRRC

      DOI: 10.1016/j.devcel.2021.02.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC8129911/
  148. www.biorxiv.org www.biorxiv.org
    A neural substrate of sex-dependent modulation of motivation by value
    3
    1. scibot 23 Mar 2023
      KG139Gsat

      DOI: 10.1101/2022.07.07.499209

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      RRIDCUR:Missing RRID:SCR_002953
    2. scibot 23 Mar 2023
      ER44Gsat

      DOI: 10.1101/2022.07.07.499209

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      RRIDCUR:Missing RRID:SCR_002953
    3. scibot 23 Mar 2023
      EY262Gsat

      DOI: 10.1101/2022.07.07.499209

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    biorxiv.org/content/10.1101/2022.07.07.499209v1
  149. www.science.org www.science.org
    Sex-specific phenotypic effects and evolutionary history of an ancient polymorphic deletion of the human growth hormone receptor
    1
    1. scibot 23 Mar 2023
      Ghrd3

      DOI: 10.1126/sciadv.abi4476

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    science.org/doi/10.1126/sciadv.abi4476
  150. www.nature.com www.nature.com
    PERK is a critical metabolic hub for immunosuppressive function in macrophages
    1
    1. scibot 23 Mar 2023
      Psat1tm1a(KOMP)Wtsi/Mmucd (Psat1fl/fl)

      DOI: 10.1038/s41590-022-01145-x

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    nature.com/articles/s41590-022-01145-x
  151. rupress.org rupress.org
    Loss of direct adrenergic innervation after peripheral nerve injury causes lymph node expansion through IFN-γ
    1
    1. scibot 23 Mar 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1084/jem.20202377

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    rupress.org/jem/article/218/8/e20202377/212257/Loss-of-direct-adrenergic-innervation-after
  152. www.sciencedirect.com www.sciencedirect.com
    MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling
    1
    1. scibot 23 Mar 2023
      Mecp2 KO

      DOI: 10.1016/j.celrep.2021.109124

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    sciencedirect.com/science/article/pii/S2211124721004630
  153. www.biorxiv.org www.biorxiv.org
    Tapping into the aging brain: In vivo microdialysis reveals mirroring pathology between preclinical models and patients with Alzheimer’s disease
    1
    1. scibot 22 Mar 2023
      B6;129-Tg(APPSwe,tauP301L)1LfaPsen1tm1Mpm/Mmjax

      DOI: 10.1101/2021.01.23.427888

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    biorxiv.org/content/10.1101/2021.01.23.427888v1
  154. link.springer.com link.springer.com
    Insight into the Animal Models for Microbiome Studies
    1
    1. scibot 22 Mar 2023
      Mutant Mouse Regions Resource Center

      DOI: 10.1007/978-981-16-3156-6_13

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    link.springer.com/chapter/10.1007/978-981-16-3156-6_13
  155. www.sciencedirect.com www.sciencedirect.com
    BMPR1a Is Required for the Optimal TGFβ1-Dependent CD207+ Langerhans Cell Differentiation and Limits Skin Inflammation through CD11c+ Cells
    1
    1. scibot 22 Mar 2023
      Bmpr2fl/fl

      DOI: 10.1016/j.jid.2022.02.014

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    sciencedirect.com/science/article/pii/S0022202X22001956
  156. www.biorxiv.org www.biorxiv.org
    Neprilysin-sensitive amyloidogenic Aβ versus IDE-sensitive soluble Aβ: a probable mechanistic cause for sporadic Alzheimer’s disease
    1
    1. scibot 22 Mar 2023
      Ide-KO

      DOI: 10.1101/2021.08.22.457281

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    biorxiv.org/content/10.1101/2021.08.22.457281v1
  157. www.jci.org www.jci.org
    DACH1 protects podocytes from experimental diabetic injury and modulates PTIP-H3K4Me3 activity
    1
    1. scibot 22 Mar 2023
      C57BL/6N-Tg[CAG-Flpo]1Afst/Mmucd

      DOI: 10.1172/JCI141279

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    jci.org/articles/view/141279
  158. www.biorxiv.org www.biorxiv.org
    Single Cell Enhancer Activity Maps Neuronal Lineages in Embryonic Mouse Basal Ganglia
    1
    1. scibot 22 Mar 2023
      MMRRC

      DOI: 10.1101/2021.01.11.426285

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    biorxiv.org/content/10.1101/2021.01.11.426285v1
  159. www.mdpi.com www.mdpi.com
    Investigation of Anxiety- and Depressive-like Symptoms in 4- and 8-Month-Old Male Triple Transgenic Mouse Models of Alzheimer&rsquo;s Disease
    1
    1. scibot 22 Mar 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.3390/ijms231810816

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    mdpi.com/1422-0067/23/18/10816
  160. www.life-science-alliance.org www.life-science-alliance.org
    Mitochondrial stress-induced GFRAL signaling controls diurnal food intake and anxiety-like behavior
    1
    1. scibot 22 Mar 2023
      Gfral

      DOI: 10.26508/lsa.202201495

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    life-science-alliance.org/content/5/11/e202201495
  161. www.biorxiv.org www.biorxiv.org
    Mitochondrial stress-induced GDF15-GFRAL axis promotes anxiety-like behavior and CRH-dependent anorexia
    1
    1. scibot 22 Mar 2023
      Gfral

      DOI: 10.1101/2021.09.22.461199

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    biorxiv.org/content/10.1101/2021.09.22.461199v1
  162. journals.biologists.com journals.biologists.com
    Promoting validation and cross-phylogenetic integration in model organism research
    1
    1. scibot 22 Mar 2023
      www.mmrrc.org

      DOI: 10.1242/dmm.049600

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    journals.biologists.com/dmm/article/15/9/dmm049600/276675/Promoting-validation-and-cross-phylogenetic
  163. www.biorxiv.org www.biorxiv.org
    Opposing regulation of short-term memory by basal ganglia direct and indirect pathways that are coactive during behavior
    1
    1. scibot 22 Mar 2023
      B6.FVB(Cg)-Tg(Drd1a-cre)EY262Gsat/Mmucd

      DOI: 10.1101/2021.12.15.472735

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    biorxiv.org/content/10.1101/2021.12.15.472735v1.full.pdf
  164. www.frontiersin.org www.frontiersin.org
    The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer’s Disease
    1
    1. scibot 22 Mar 2023
      5xFAD

      DOI: 10.3389/fnins.2021.768646

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    frontiersin.org/articles/10.3389/fnins.2021.768646/full
  165. www.mdpi.com www.mdpi.com
    Retinal Photoreceptor Protection in an AMD-Related Mouse Model by Selective Sigma-1 or Sigma-2 Receptor Modulation
    1
    1. scibot 22 Mar 2023
      OprsGt (IRESBetageo) 33Lex

      DOI: 10.3390/genes13122386

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    mdpi.com/2073-4425/13/12/2386
  166. link.springer.com link.springer.com
    Genetic quality: a complex issue for experimental study reproducibility
    1
    1. scibot 22 Mar 2023
      MMRRC

      DOI: 10.1007/s11248-022-00314-w

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    link.springer.com/article/10.1007/s11248-022-00314-w
  167. www.nature.com www.nature.com
    Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease
    1
    1. scibot 22 Mar 2023
      5xFAD

      DOI: 10.1038/s41586-021-03734-6

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    nature.com/articles/s41586-021-03734-6
  168. www.sciencedirect.com www.sciencedirect.com
    Deficiency of the sedoheptulose kinase (Shpk) does not alter the ability of hematopoietic stem cells to rescue cystinosis in the mouse model
    1
    1. scibot 22 Mar 2023
      C57BL/6 Shpk−/−

      DOI: 10.1016/j.ymgme.2021.11.006

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    sciencedirect.com/science/article/pii/S1096719221008246
  169. www.mdpi.com www.mdpi.com
    Consideration of Gut Microbiome in Murine Models of Diseases
    1
    1. scibot 22 Mar 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.3390/microorganisms9051062

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    mdpi.com/2076-2607/9/5/1062
  170. www.nature.com www.nature.com
    Single-cell analysis of skin immune cells reveals an Angptl4-ifi20b axis that regulates monocyte differentiation during wound healing
    1
    1. scibot 22 Mar 2023
      Mutant Mouse Regional Resource Center

      DOI: 10.1038/s41419-022-04638-7

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    nature.com/articles/s41419-022-04638-7
  171. www.sciencedirect.com www.sciencedirect.com
    A novel DPH5-related diphthamide-deficiency syndrome causing embryonic lethality or profound neurodevelopmental disorder
    1
    1. scibot 22 Mar 2023
      C57BL/6NCrl-Dph5em1(IMPC)Mbp/Mmucd

      DOI: 10.1016/j.gim.2022.03.014

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    sciencedirect.com/science/article/pii/S1098360022007043
  172. www.biorxiv.org www.biorxiv.org
    Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality
    1
    1. scibot 22 Mar 2023
      129S6/SvEvTac x C57BL/6NCrl

      DOI: 10.1101/2021.07.05.451131

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    biorxiv.org/content/10.1101/2021.07.05.451131v1
  173. rupress.org rupress.org
    Viral infection modulates Qa-1b in infected and bystander cells to properly direct NK cell killing
    1
    1. scibot 22 Mar 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1084/jem.20201782

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    rupress.org/jem/article/218/5/e20201782/211920/Viral-infection-modulates-Qa-1b-in-infected-and
  174. www.sciencedirect.com www.sciencedirect.com
    Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice
    1
    1. scibot 21 Mar 2023
      Mutant Mouse Resource and Research Center

      DOI: 10.1016/j.xcrm.2021.100434

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    sciencedirect.com/science/article/pii/S2666379121002962
  175. www.biorxiv.org www.biorxiv.org
    Multi-omics analysis of mouse fecal microbiome reveals supplier-dependent functional differences and novel metagenome-assembled genomes
    1
    1. scibot 21 Mar 2023
      CD-1

      DOI: 10.1101/2022.09.12.507288

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    biorxiv.org/content/10.1101/2022.09.12.507288v1
  176. www.nature.com www.nature.com
    Ventral arkypallidal neurons inhibit accumbal firing to promote reward consumption
    1
    1. scibot 21 Mar 2023
      MMRRC

      DOI: 10.1038/s41593-020-00772-7

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    nature.com/articles/s41593-020-00772-7
  177. www.sciencedirect.com www.sciencedirect.com
    A common SNP in Chrna5 enhances morphine reward in female mice
    1
    1. scibot 21 Mar 2023
      Chrna 5 SNP

      DOI: 10.1016/j.neuropharm.2022.109218

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    sciencedirect.com/science/article/pii/S0028390822002775
  178. www.sciencedirect.com www.sciencedirect.com
    P2Y2 receptor antagonism resolves sialadenitis and improves salivary flow in a Sjögren’s syndrome mouse model
    1
    1. scibot 21 Mar 2023
      NOD.H-2h4 DKO

      DOI: 10.1016/j.archoralbio.2021.105067

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    sciencedirect.com/science/article/pii/S0003996921000303
  179. link.springer.com link.springer.com
    The gut microbiome of laboratory mice: considerations and best practices for translational research
    1
    1. scibot 21 Mar 2023
      MMRRC

      DOI: 10.1007/s00335-021-09863-7

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    link.springer.com/article/10.1007/s00335-021-09863-7
  180. academic.oup.com academic.oup.com
    INO80 promotes H2A.Z occupancy to regulate cell fate transition in pluripotent stem cells
    1
    1. scibot 21 Mar 2023
      E14Tg2a ESCs

      DOI: 10.1093/nar/gkab476

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    academic.oup.com/nar/article/49/12/6739/6303461
  181. www.sciencedirect.com www.sciencedirect.com
    Tetrahydroxystilbene glycoside improves endothelial dysfunction and hypertension in obese rats: The role of omentin-1
    1
    1. scibot 21 Mar 2023
      OMT-/- B6; 129S5-Itln1tm1Lex/Mmucd

      DOI: 10.1016/j.bcp.2021.114489

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    sciencedirect.com/science/article/pii/S000629522100085X
  182. www.sciencedirect.com www.sciencedirect.com
    NaV1.1 haploinsufficiency impairs glutamatergic and GABAergic neuron function in the thalamus
    1
    1. scibot 21 Mar 2023
      129S6/SvEvTac

      DOI: 10.1016/j.nbd.2022.105672

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    sciencedirect.com/science/article/pii/S0969996122000638
  183. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted disruption of Gdi2 causes early embryonic lethality
    1
    1. scibot 21 Mar 2023
      Gdi2

      DOI: 10.1016/j.placenta.2022.05.005

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    pmc.ncbi.nlm.nih.gov/articles/PMC11423266/
  184. academic.oup.com academic.oup.com
    RNA marker modifications reveal the necessity for rigorous preparation protocols to avoid artifacts in epitranscriptomic analysis
    1
    1. scibot 21 Mar 2023
      MMRRC

      DOI: 10.1093/nar/gkab1150

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    academic.oup.com/nar/article/50/8/4201/6446534
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kdm6b Haploinsufficiency Causes ASD/ADHD-Like Behavioral Deficits in Mice
    1
    1. scibot 21 Mar 2023
      Kdm6b-cKO

      DOI: 10.3389/fnbeh.2022.905783

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    ncbi.nlm.nih.gov/pmc/articles/PMC9194811/
  186. journals.biologists.com journals.biologists.com
    Animals, quality and the pursuit of relevance
    1
    1. scibot 21 Mar 2023
      Mutant Mouse Resource and Research Centers

      DOI: 10.1242/dmm.049775

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    journals.biologists.com/dmm/article/15/10/dmm049775/277008/Animals-quality-and-the-pursuit-of-relevance
  187. www.sciencedirect.com www.sciencedirect.com
    LCCL peptide cleavage after noise exposure exacerbates hearing loss and is associated with the monocyte infiltration in the cochlea
    1
    1. scibot 21 Mar 2023
      Coch p.G88E

      DOI: 10.1016/j.heares.2021.108378

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    sciencedirect.com/science/article/pii/S0378595521002124
  188. www.nature.com www.nature.com
    Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state
    3
    1. scibot 21 Mar 2023
      A2a-Cre

      DOI: 10.1038/s41593-022-01021-9

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    2. scibot 21 Mar 2023
      Drd2-Cre

      DOI: 10.1038/s41593-022-01021-9

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    3. scibot 21 Mar 2023
      Drd1-Cre

      DOI: 10.1038/s41593-022-01021-9

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    nature.com/articles/s41593-022-01021-9
  189. www.nature.com www.nature.com
    Rats on the rise
    1
    1. scibot 21 Mar 2023
      Mutant Mouse Resource & Research Center

      DOI: 10.1038/s41684-021-00812-0

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    nature.com/articles/s41684-021-00812-0
  190. www.biorxiv.org www.biorxiv.org
    Prevalent mouse phenotypes in the unexplored druggable genome
    1
    1. scibot 21 Mar 2023
      MMRRC

      DOI: 10.1101/2021.11.08.467777

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    biorxiv.org/content/10.1101/2021.11.08.467777v1
  191. link.springer.com link.springer.com
    Acute Traumatic Brain Injury-Induced Neuroinflammatory Response and Neurovascular Disorders in the Brain
    1
    1. scibot 21 Mar 2023
      CD-1

      DOI: 10.1007/s12640-020-00288-9

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    link.springer.com/article/10.1007/s12640-020-00288-9
  192. www.biorxiv.org www.biorxiv.org
    Cell type and subcellular compartment specific APEX2 proximity labeling proteomics in the mouse brain
    1
    1. scibot 21 Mar 2023
      Drd1Cre

      DOI: 10.1101/2021.04.08.439091

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    biorxiv.org/content/10.1101/2021.04.08.439091v1
  193. www.mdpi.com www.mdpi.com
    The Effect of Common Viral Inactivation Techniques on 16S rRNA Amplicon-Based Analysis of the Gut Microbiota
    1
    1. scibot 18 Mar 2023
      CD-1

      DOI: 10.3390/microorganisms9081755

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    mdpi.com/2076-2607/9/8/1755
  194. www.nature.com www.nature.com
    Mice on the move
    1
    1. scibot 18 Mar 2023
      MMRRC

      DOI: 10.1038/s41684-021-00829-5

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    nature.com/articles/s41684-021-00829-5
  195. www.nature.com www.nature.com
    cAMP-Fyn signaling in the dorsomedial striatum direct pathway drives excessive alcohol use
    2
    1. scibot 18 Mar 2023
      AdoraA2-Cre (A2A-Cre)

      DOI: 10.1038/s41386-020-0712-1

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      RRID:SCR_002953 RRIDCUR:Missing
    2. scibot 18 Mar 2023
      Drd1a-Cre (D1-Cre)

      DOI: 10.1038/s41386-020-0712-1

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    nature.com/articles/s41386-020-0712-1
  196. www.sciencedirect.com www.sciencedirect.com
    Divergent functions of IL-17-family cytokines in DSS colitis: Insights from a naturally-occurring human mutation in IL-17F
    1
    1. scibot 18 Mar 2023
      Il17fS65L/S65L

      DOI: 10.1016/j.cyto.2021.155715

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    sciencedirect.com/science/article/pii/S1043466621003045
  197. link.springer.com link.springer.com
    Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons
    1
    1. scibot 18 Mar 2023
      Drd2-Cre

      DOI: 10.1007/s12264-021-00698-5

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    link.springer.com/article/10.1007/s12264-021-00698-5
  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional dissociation of behavioral effects from acetylcholine and glutamate released from cholinergic striatal interneurons
    1
    1. scibot 18 Mar 2023
      D2‐Cre

      DOI: 10.1096/fj.202101425R

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    ncbi.nlm.nih.gov/pmc/articles/PMC9303754/
  199. link.springer.com link.springer.com
    L-cysteine modulates visceral nociception mediated by the CaV2.3 R-type calcium channels
    1
    1. scibot 17 Mar 2023
      MMRRC

      DOI: 10.1007/s00424-022-02674-y

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    link.springer.com/article/10.1007/s00424-022-02674-y
  200. www.sciencedirect.com www.sciencedirect.com
    A Role for Protease Activated Receptor Type 3 (PAR3) in Nociception Demonstrated Through Development of a Novel Peptide Agonist
    1
    1. scibot 17 Mar 2023
      C57Bl6/J

      DOI: 10.1016/j.jpain.2020.12.006

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    sciencedirect.com/science/article/pii/S1526590021000018
  201. www.spandidos-publications.com www.spandidos-publications.com
    Targeted disruption of Rab1a causes early embryonic lethality
    1
    1. scibot 17 Mar 2023
      Rab1a

      DOI: 10.3892/ijmm.2022.5101

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    spandidos-publications.com/10.3892/ijmm.2022.5101
  202. www.biorxiv.org www.biorxiv.org
    Topologically Associating Domain Boundaries are Commonly Required for Normal Genome Function
    1
    1. scibot 17 Mar 2023
      MMRRC

      DOI: 10.1101/2021.05.06.443037

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    biorxiv.org/content/10.1101/2021.05.06.443037v1