407 Matching Annotations
  1. Jan 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC9827110/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9401506/
  5. Dec 2022
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9177734/
  7. Nov 2022
  8. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    sciencedirect.com/science/article/abs/pii/S1097276522010644
  9. aacrjournals.org aacrjournals.org
    DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1
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    aacrjournals.org/cancerrescommun/article/2/11/1388/710518/DDR2-Coordinates-EMT-and-Metabolic-Reprogramming
  10. link.springer.com link.springer.com
    The LncRNA MIAT is identified as a regulator of stemness-associated transcript in glioma
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    link.springer.com/article/10.1007/s11033-022-07962-5
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    Dissecting the genetic and microenvironmental factors of gastric tumorigenesis in mice
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    sciencedirect.com/science/article/pii/S2211124722013328
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9621136/
  13. Oct 2022
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    Circadian transcriptional pathway atlas highlights a proteasome switch in intermittent fasting
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    sciencedirect.com/science/article/pii/S2211124722014036
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2-dependent glutaminolysis pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC9524954/
  16. alzres.biomedcentral.com alzres.biomedcentral.com
    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
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    alzres.biomedcentral.com/articles/10.1186/s13195-022-01096-3
  17. www.science.org www.science.org
    Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2–dependent glutaminolysis pathway
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    science.org/doi/10.1126/sciadv.abq0117
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct biomarker profiles and TCR sequence diversity characterize the response to PD-L1 blockade in a mouse melanoma model
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    ncbi.nlm.nih.gov/pmc/articles/PMC9533714/
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    A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation
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    sciencedirect.com/science/article/pii/S2666979X22001409
  20. Sep 2022
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biological misinterpretation of transcriptional signatures in tumor samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data
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    ncbi.nlm.nih.gov/pmc/articles/PMC9475248/
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    A small proportion of X-linked genes contribute to X chromosome upregulation in early embryos via BRD4-mediated transcriptional activation
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    sciencedirect.com/science/article/pii/S0960982222013811
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    Artificial gravity partially protects space-induced neurological deficits in Drosophila melanogaster
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    sciencedirect.com/science/article/pii/S2211124722010993
  24. Aug 2022
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circulating microRNA: Myocardium-derived prenatal biomarker of ventricular septal defects
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    ncbi.nlm.nih.gov/pmc/articles/PMC9403759/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Race-associated molecular changes in gynecologic malignancies
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    ncbi.nlm.nih.gov/pmc/articles/PMC9390975/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of CXCL10 and CXCL11 as the candidate genes involving the development of colitis-associated colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9393335/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC8349875/
  29. Jun 2022
  30. 52.53.155.43 52.53.155.43
    KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model
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    52.53.155.43/bdb24171b1be34ca6d57a161f01e6067da1b2327/physiolgenomics.00134.2021-html.html
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    MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines
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    sciencedirect.com/science/article/pii/S2211124722007744
  32. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus
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    sciencedirect.com/science/article/pii/S2211124722007604
  33. aacrjournals.org aacrjournals.org
    Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
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    aacrjournals.org/cancerres/article/82/11/2141/699099/Phosphorylation-of-SHP2-at-Tyr62-Enables-Acquired
  34. May 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment
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    sciencedirect.com/science/article/pii/S2211124722006192
  36. www.sciencedirect.com www.sciencedirect.com
    BMAL1 modulates smooth muscle cells phenotypic switch towards fibroblast-like cells and stabilizes atherosclerotic plaques by upregulating YAP1
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    sciencedirect.com/science/article/pii/S092544392200120X
  37. aacrjournals.org aacrjournals.org
    Tumor ENPP1(CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
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    aacrjournals.org/cancerdiscovery/article/12/5/1356/694562/Tumor-ENPP1-CD203a-Haptoglobin-Axis-Exploits
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    Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 module
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    sciencedirect.com/science/article/pii/S2589004222005521
  39. Apr 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Sex disparities in influenza: A multiscale network analysis
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  41. www.sciencedirect.com www.sciencedirect.com
    Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches
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    sciencedirect.com/science/article/pii/S1074761322001297
  42. aacrjournals.org aacrjournals.org
    Lactate rewires lipid metabolism and sustains a metabolic-epigenetic axis in prostate cancer
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    aacrjournals.org/cancerres/article/82/7/1267/694059/Lactate-Rewires-Lipid-Metabolism-and-Sustains-a
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cells retrace a stepwise differentiation program during malignant progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7611766/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tenascin-C can Serve as an Indicator for the Immunosuppressive Microenvironment of Diffuse Low-Grade Gliomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC8966496/
  45. Mar 2022
  46. elifesciences.org elifesciences.org
    Novel insights from a multiomics dissection of the Hayflick limit
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    elifesciences.org/articles/70283
  47. f1000research.com f1000research.com
    Characterizing gene expression in an&nbsp;<i>in vitro</i> biomechanical strain model of joint health
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    f1000research.com/articles/11-296
  48. aacrjournals.org aacrjournals.org
    Race-associated Molecular Changes in Gynecologic Malignancies
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    aacrjournals.org/cancerrescommun/article/2/2/99/681553/Race-associated-Molecular-Changes-in-Gynecologic
  49. Feb 2022
  50. elifesciences.org elifesciences.org
    FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
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    elifesciences.org/articles/71892
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC7704921/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mediator of DNA damage checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive lobular carcinoma of the breast
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    ncbi.nlm.nih.gov/pmc/articles/PMC8349796/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-Omics Profiling Suggesting Intratumoral Mast Cells as Predictive Index of Breast Cancer Lung Metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8801492/
  54. Jan 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy
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    ncbi.nlm.nih.gov/pmc/articles/PMC8758788/
  56. www.sciencedirect.com www.sciencedirect.com
    Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy
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    sciencedirect.com/science/article/pii/S1534580721009965
  57. Dec 2021
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC8639143/
  59. Nov 2021
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interdependence of neural network dysfunction and microglial alterations in Alzheimer’s disease-related models
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    ncbi.nlm.nih.gov/pmc/articles/PMC8561005/
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    Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition
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    sciencedirect.com/science/article/pii/S2211124721013899
  62. Oct 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Establishment of a prognostic model of ten transcription factors in gastric cancer
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    sciencedirect.com/science/article/pii/S0888754321003736
  64. www.nature.com www.nature.com
    Single-cell RNA sequencing for the identification of early-stage lung cancer biomarkers from circulating blood
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    nature.com/articles/s41525-021-00248-y
  65. www.sciencedirect.com www.sciencedirect.com
    Role of miR-2392 in driving SARS-CoV-2 infection
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    sciencedirect.com/science/article/pii/S2211124721013036
  66. Sep 2021
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC8463072/
  68. www.sciencedirect.com www.sciencedirect.com
    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
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    sciencedirect.com/science/article/pii/S1934590921003805
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave
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    ncbi.nlm.nih.gov/pmc/articles/PMC8425950/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
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    ncbi.nlm.nih.gov/pmc/articles/PMC8423448/
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    Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia
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    sciencedirect.com/science/article/pii/S107476132100337X
  72. Aug 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity
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    sciencedirect.com/science/article/pii/S2211124721009219
  74. journals.sagepub.com journals.sagepub.com
    SAGE Journals: Your gateway to world-class research journals
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    journals.sagepub.com/doi/full/10.1177/1759091419843393
  75. elifesciences.org elifesciences.org
    Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway
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    elifesciences.org/articles/25157
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The COVIDome Explorer researcher portal
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    ncbi.nlm.nih.gov/pmc/articles/PMC8316015/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A 5‐gene prognostic nomogram predicting survival probability of glioblastoma patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC6456771/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  81. Jul 2021
  82. onlinelibrary.wiley.com onlinelibrary.wiley.com
    DNA hypermethylation is associated with invasive phenotype of malignant melanoma
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    onlinelibrary.wiley.com/doi/full/10.1111/exd.14047
  83. www.nature.com www.nature.com
    Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis
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    nature.com/articles/s41467-019-11327-1
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    journals.sagepub.com/doi/abs/10.1177/1759091419843393
  85. elifesciences.org elifesciences.org
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    onlinelibrary.wiley.com/doi/full/10.1002/brb3.1258
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response
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    ncbi.nlm.nih.gov/pmc/articles/PMC6342529/
  88. www.nature.com www.nature.com
    The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy
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    nature.com/articles/s41419-019-1950-1
  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SNAIL1 employs β‐Catenin‐LEF1 complexes to control colorectal cancer cell invasion and proliferation
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32644
  90. www.eneuro.org www.eneuro.org
    Mega-analysis of gene expression in mouse models of Alzheimer’s disease
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    eneuro.org/content/6/6/ENEURO.0226-19.2019
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    Liver Is a Generative Site for the B Cell Response to Ehrlichia muris
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  92. elifesciences.org elifesciences.org
    PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD
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    elifesciences.org/articles/48625
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    Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC6242466/
  95. europepmc.org europepmc.org
    Inducible and reversible phenotypes in a novel mouse model of Friedreich's Ataxia.
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    europepmc.org/articles/PMC5736353/
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    Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway
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  97. www.nature.com www.nature.com
    A chemical toolbox for the study of bromodomains and epigenetic signaling
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    nature.com/articles/s41467-019-09672-2
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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    sciencedirect.com/science/article/pii/S1535610819300406
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    The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging
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    sciencedirect.com/science/article/pii/S1097276518310049
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    A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling
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    The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice
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    sciencedirect.com/science/article/pii/S2451945618303465
  102. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14469
  103. www.sciencedirect.com www.sciencedirect.com
    Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging
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  104. www.sciencedirect.com www.sciencedirect.com
    An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis
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    sciencedirect.com/science/article/pii/S1074761318304266
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast
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    ncbi.nlm.nih.gov/pmc/articles/PMC8263057/
  106. Jun 2021
  107. www.frontiersin.org www.frontiersin.org
    Monocytic Ontogeny of Regenerated Macrophages Characterizes the Mesotheliomagenic Responses to Carbon Nanotubes
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