6,202 Matching Annotations
  1. Apr 2023
  2. www.nature.com www.nature.com
    Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1
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    nature.com/articles/s41408-023-00826-6
  3. www.embopress.org www.embopress.org
    RAF1 deficiency causes a lethal syndrome that underscores RTK signaling during embryogenesis
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    embopress.org/doi/10.15252/emmm.202217078
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemical-proteomics Identify Peroxiredoxin-1 as an Actionable Target in Triple-negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10092761/
  5. www.sciencedirect.com www.sciencedirect.com
    Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
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    sciencedirect.com/science/article/pii/S1097276523002113
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunogenicity and protective efficacy of GBP510/AS03 vaccine against SARS-CoV-2 delta challenge in rhesus macaques
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    ncbi.nlm.nih.gov/pmc/articles/PMC9947939/
  7. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13424
  8. www.cell.com www.cell.com
    Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development
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    cell.com/developmental-cell/fulltext/S1534-5807(23)00132-6
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    IKZF4 acts as a novel tumor suppressor in non–small cell lung cancer by suppressing Notch signaling pathway
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    sciencedirect.com/science/article/pii/S0898656823000931
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types
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    ncbi.nlm.nih.gov/pmc/articles/PMC10028905/
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    Distinct regulation of EZH2 and its repressive H3K27me3 mark in Polyomavirus -positive and -negative Merkel cell carcinoma
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    sciencedirect.com/science/article/pii/S0022202X23019735
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intronic Cis-Element DR8 in hTERT Is Bound by Splicing Factor SF3B4 and Regulates hTERT Splicing in Non-Small Cell Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9532359/
  13. 52.53.155.43 52.53.155.43
    Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
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    52.53.155.43/2577421dac7a2392d92c9ebbcebbed6a87779755/2023.02.24.529970v1.full-html.html
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    miR‐548ag functions as an oncogene by suppressing MOB1B in the development of obesity‐related endometrial cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10067393/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-suppressor scanning for systematic discovery of drug resistance mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC10073897/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10055206/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serum neutralizing capacity and T-cell response against the omicron BA.1 variant in seropositive children and their parents one year after SARS-CoV-2 infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC10083310/
  18. www.sciencedirect.com www.sciencedirect.com
    N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S266637912300112X
  19. reader.elsevier.com reader.elsevier.com
    Phosphorylation barcodes direct biased chemokine signaling at CXCR3
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    reader.elsevier.com/reader/sd/pii/S2451945623000855
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ad26.COV2.S and SARS-CoV-2 Spike Protein Ferritin Nanoparticle Vaccine Protect Against SARS-CoV-2 Omicron BA.5 Challenge in Macaques
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    ncbi.nlm.nih.gov/pmc/articles/PMC10040355/
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    γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons
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    sciencedirect.com/science/article/pii/S0896627323002088
  22. www.embopress.org www.embopress.org
    The CEP170B-KIF2A complex destabilizes microtubule minus ends to generate polarized microtubule network
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    embopress.org/doi/full/10.15252/embj.2022112953
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    Targeted m6A demethylation of ITGA6 mRNA by a multisite dCasRx–m6A editor inhibits bladder cancer development
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    sciencedirect.com/science/article/pii/S2090123223000929
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    Ultra-rare complement factor 8 coding variants in families with age-related macular degeneration
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    sciencedirect.com/science/article/pii/S2589004223004947
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    The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia
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    sciencedirect.com/science/article/pii/S1534580723000990
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    Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars
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    sciencedirect.com/science/article/pii/S2666979X23000599
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A general method for quantitative fractionation of mammalian cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10040634/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of heterogeneous metabolism in hepatocellular carcinoma identifies new therapeutic target and treatment strategy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10060979/
  29. Mar 2023
  30. www.biorxiv.org www.biorxiv.org
    Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A
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    biorxiv.org/content/10.1101/2023.02.17.528918v1
  31. www.mdpi.com www.mdpi.com
    Screening of Efficient Adjuvants for the RBD-Based Subunit Vaccine of SARS-CoV-2
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    mdpi.com/2076-393X/11/4/713
  32. www.sciencedirect.com www.sciencedirect.com
    Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
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    sciencedirect.com/science/article/pii/S258900422300487X
  33. www.sciencedirect.com www.sciencedirect.com
    Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1
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    sciencedirect.com/science/article/pii/S2211124723003327
  34. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Switching ubiquitous and muscle-specific isoforms of mitochondrial respiratory complex IV in skeletal muscle fine-tunes complex IV activity
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201223RR
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    A micropattern-based assay to study contact inhibition of locomotion and entosis of adherent human and canine cells in vitro
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    sciencedirect.com/science/article/pii/S2666166723001442
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    Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120
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    sciencedirect.com/science/article/pii/S2451945623000624
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    Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner
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    sciencedirect.com/science/article/pii/S2211124723001900
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    An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay
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    sciencedirect.com/science/article/pii/S2666166723001570
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 affects diet-induced adiposity in female mice and co-regulates peroxisome proliferator-activated receptor PPARγ target genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10034470/
  40. www.biorxiv.org www.biorxiv.org
    The acetylase activity of Cdu1 protects Chlamydia effectors from degradation to regulate bacterial exit from infected cells
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    biorxiv.org/content/10.1101/2023.02.28.530337v2
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10002699/
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    TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
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    sciencedirect.com/science/article/pii/S0021925823002636
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    Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations
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    sciencedirect.com/science/article/pii/S2211124723001936
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    Differential Optineurin expression controls TGFβ signaling and is a key determinant for metastasis of triple negative breast cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34483
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutating novel interaction sites in NRP1 reduces SARS-CoV-2 spike protein internalization
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    ncbi.nlm.nih.gov/pmc/articles/PMC9957656/
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    A central chaperone-like role for 14-3-3 proteins in human cells
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    sciencedirect.com/science/article/pii/S1097276523001211
  47. 52.53.155.43 52.53.155.43
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    A combinatorial approach to uncover an additional Integrator subunit
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    sciencedirect.com/science/article/pii/S2211124723002553
  49. www.cell.com www.cell.com
    ER proteostasis regulators cell-non-autonomously control sleep
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    cell.com/cell-reports/fulltext/S2211-1247(23)00278-4
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging Tumor Microenvironment Infiltration in Pancreatic Cancer to Identify Gene Signatures Related to Prognosis and Immunotherapy Response
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    ncbi.nlm.nih.gov/pmc/articles/PMC10000708/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10014071/
  52. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    CEBPB upregulates P4HA2 to promote the malignant biological behavior in IDH1 wildtype glioma
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    faseb.onlinelibrary.wiley.com/doi/epdf/10.1096/fj.202201244RRRR
  53. www.sciencedirect.com www.sciencedirect.com
    Transient receptor potential canonical type 6 (TRPC6) O-GlcNAcylation at Threonine-221 plays potent role in channel regulation
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    sciencedirect.com/science/article/pii/S2589004223003711
  54. www.sciencedirect.com www.sciencedirect.com
    In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
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    sciencedirect.com/science/article/pii/S2666979X23000368
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    Oxygen toxicity causes cyclic damage by destabilizing specific Fe-S cluster-containing protein complexes
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    sciencedirect.com/science/article/pii/S1097276523001168
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    Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity
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    sciencedirect.com/science/article/pii/S1550413123000499
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
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    Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer
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    sciencedirect.com/science/article/pii/S2352396423000658
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin
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    ncbi.nlm.nih.gov/pmc/articles/PMC9986520/
  60. www.nature.com www.nature.com
    Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway
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    nature.com/articles/s12276-023-00957-7
  61. link.springer.com link.springer.com
    Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons
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    link.springer.com/article/10.1007/s12035-023-03281-3
  62. link.springer.com link.springer.com
    S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) inhibits lung cancer tumorigenesis by regulating cell plasticity
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    link.springer.com/article/10.1186/s13062-023-00364-y
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Inhibition of Smoothened and the DNA Damage Checkpoint WEE1 Exerts Antitumor Activity in Cholangiocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9978885/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile
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    ncbi.nlm.nih.gov/pmc/articles/PMC9902290/
  65. www.biorxiv.org www.biorxiv.org
    A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites
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    biorxiv.org/content/10.1101/2023.01.31.526483v3
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16018
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16036
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16046
  69. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16050
  70. www.biorxiv.org www.biorxiv.org
    High-throughput screening of functional neo-antigens and their specific TCRs via the Jurkat reporter system combined with droplet microfluidics
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    biorxiv.org/content/10.1101/2023.02.20.529171v1
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC9961888/
  72. Feb 2023
  73. academic.oup.com academic.oup.com
    Follistatin forms a stable complex with Inhibin A that does not interfere with Activin A antagonism
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    academic.oup.com/endo/article/164/3/bqad017/7010688
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    E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity
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    sciencedirect.com/science/article/pii/S1097276523000424
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    Illuminating cellular and extracellular vesicle-mediated communication via a split-Nanoluc reporter in vitro and in vivo
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    sciencedirect.com/science/article/pii/S2667237523000231
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    An adverse tumor-protective effect of IDO1 inhibition
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    sciencedirect.com/science/article/pii/S2666379123000332
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein composition of axonal dopamine release sites in the striatum
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    ncbi.nlm.nih.gov/pmc/articles/PMC9937654/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9388591/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability
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    ncbi.nlm.nih.gov/pmc/articles/PMC9924825/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species
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    ncbi.nlm.nih.gov/pmc/articles/PMC9931222/
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    CRISPR activation screening in a mouse model for drivers of hepatocellular carcinoma growth and metastasis
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    sciencedirect.com/science/article/pii/S2589004223001761
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13375
  83. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    HSF1 activates the FOXO3a–ΔNp63α–CDK4 axis to promote head and neck squamous cell carcinoma cell proliferation and tumor growth
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14588
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    Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility
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    nature.com/articles/s41596-022-00795-3
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    XPO1 intensifies sorafenib resistance by stabilizing acetylation of NPM1 and enhancing epithelial-mesenchymal transition in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S0753332223001907
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC9910834/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9917443/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs
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    ncbi.nlm.nih.gov/pmc/articles/PMC9910744/
  89. 52.53.155.43 52.53.155.43
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