4,894 Matching Annotations
  1. Feb 2021
  2. www.nature.com www.nature.com
    Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress
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    nature.com/articles/s42255-020-00325-z
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    Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins
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    cell.com/structure/fulltext/S0969-2126(20)30480-9
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    Calmodulin binds to Drosophila TRP with an unexpected mode
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    cell.com/structure/abstract/S0969-2126(20)30463-9
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements
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    ncbi.nlm.nih.gov/pmc/articles/PMC7550205/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS
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    ncbi.nlm.nih.gov/pmc/articles/PMC7321023/
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    A genetically encoded fluorescent sensor for rapid and specific in vivo detection of norepinephrine
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    ncbi.nlm.nih.gov/pmc/articles/PMC6533151/
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nogo receptor antagonist LOTUS exerts suppression on axonal growth‐inhibiting receptor PIR‐B
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15013
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    Truncating mutations in SHANK3 associated with global developmental delay interfere with nuclear β‐catenin signaling
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15014
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    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15070
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    Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7234812/
  12. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness
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    biosignaling.biomedcentral.com/articles/10.1186/s12964-021-00710-5
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    The kinase PDK1 is critical for promoting T follicular helper cell differentiation
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    elifesciences.org/articles/61406
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    Definition of a small core transcriptional circuit regulated by AML1-ETO
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30897-2
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    Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex
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    sciencedirect.com/science/article/pii/S2211124721000838
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    Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus
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    ncbi.nlm.nih.gov/pmc/articles/PMC7882221/
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    Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion
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    sciencedirect.com/science/article/pii/S2211124721000164
  18. mcr.aacrjournals.org mcr.aacrjournals.org
    RCC2 Promotes Esophageal Cancer Growth by Regulating Activity and Expression of the Sox2 Transcription Factor
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    mcr.aacrjournals.org/content/18/11/1660
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    Identification of PARP-7 substrates reveals a role for MARylation in microtubule control in ovarian cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7884071/
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    DNA origami signposts for identifying proteins on cell membranes by electron cryotomography
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    sciencedirect.com/science/article/pii/S0092867421000763
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    MiR-3121-3p promotes tumor invasion and metastasis by suppressing Rap1GAP in papillary thyroid cancer in vitro
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    atm.amegroups.com/article/view/49433/html
  22. elifesciences.org elifesciences.org
    The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure
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    elifesciences.org/articles/61797
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    Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2
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    sciencedirect.com/science/article/pii/S2211124721001042
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    The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
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    sciencedirect.com/science/article/pii/S1097276520309886
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    Ctdnep1 and Eps8L2 regulate dorsal actin cables for nuclear positioning during cell migration
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    sciencedirect.com/science/article/pii/S0960982221000403
  26. www.nature.com www.nature.com
    Scalable characterization of the PAM requirements of CRISPR–Cas enzymes using HT-PAMDA
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    nature.com/articles/s41596-020-00465-2
  27. elifesciences.org elifesciences.org
    Diverse viral proteases activate the NLRP1 inflammasome
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    elifesciences.org/articles/60609
  28. elifesciences.org elifesciences.org
    Seizures are a druggable mechanistic link between TBI and subsequent tauopathy
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    elifesciences.org/articles/58744
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    An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism
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    sciencedirect.com/science/article/pii/S221112472100036X
  30. Jan 2021
  31. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel G protein‐biased agonist at the μ opioid receptor induces substantial receptor desensitization through G protein‐coupled receptor kinase
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15334
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutations in SKI in Shprintzen–Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization
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    ncbi.nlm.nih.gov/pmc/articles/PMC7834018/
  33. www.sciencedirect.com www.sciencedirect.com
    DCAF14 promotes stalled fork stability to maintain genome integrity
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    sciencedirect.com/science/article/pii/S2211124720316582
  34. www.sciencedirect.com www.sciencedirect.com
    Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution
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    sciencedirect.com/science/article/pii/S2211124720316594
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    Proton-activated chloride channel PAC regulates endosomal acidification and transferrin receptor-mediated endocytosis
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    sciencedirect.com/science/article/pii/S2211124720316727
  36. www.sciencedirect.com www.sciencedirect.com
    Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A
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    sciencedirect.com/science/article/pii/S2211124720316697
  37. www.nature.com www.nature.com
    Precision genome editing using cytosine and adenine base editors in mammalian cells
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    nature.com/articles/s41596-020-00450-9
  38. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Monomeric/dimeric forms of Fgf15/FGF19 show differential activity in hepatocyte proliferation and metabolic function
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002203R
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Infectious titres of human papillomaviruses (HPVs) in patient lesions, methodological considerations in evaluating HPV infectivity and implications for the efficacy of high-level disinfectants
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    ncbi.nlm.nih.gov/pmc/articles/PMC7808919/
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    Affinity enrichment and identification of inositol poly- and pyrophosphate interactomes
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    sciencedirect.com/science/article/pii/S2666166720302641
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA binding RING E3-ligase DZIP3/hRUL138 stabilizes Cyclin D1 to drive cell cycle and cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7116596/
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    The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling
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    sciencedirect.com/science/article/pii/S221112472031620X
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    The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway
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    sciencedirect.com/science/article/pii/S221112472031648X
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    Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
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    sciencedirect.com/science/article/pii/S2666379120302433
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels
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    ncbi.nlm.nih.gov/pmc/articles/PMC7806264/
  46. www.sciencedirect.com www.sciencedirect.com
    Prolonged mitosis causes separase deregulation and chromosome nondisjunction
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    sciencedirect.com/science/article/pii/S2211124720316417
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic genetic variation revealed in diverse Hsp104 homologs
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    ncbi.nlm.nih.gov/pmc/articles/PMC7785292/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FAIM Is Regulated by MiR-206, MiR-1-3p and MiR-133b
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    ncbi.nlm.nih.gov/pmc/articles/PMC7785887/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes
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    ncbi.nlm.nih.gov/pmc/articles/PMC7758071/
  50. www.sciencedirect.com www.sciencedirect.com
    linc-AAM Facilitates Gene Expression Contributing to Macrophage Activation and Adaptive Immune Responses
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    sciencedirect.com/science/article/pii/S2211124720315734
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    Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression
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    sciencedirect.com/science/article/pii/S2211124720315114
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    Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates
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    sciencedirect.com/science/article/pii/S2211124720315515
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM5A mutations identified in autism spectrum disorder using forward genetics
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    ncbi.nlm.nih.gov/pmc/articles/PMC7755391/
  54. Dec 2020
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mechanism of kinesin inhibition by kinesin-binding protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC7746232/
  56. www.sciencedirect.com www.sciencedirect.com
    Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth
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    sciencedirect.com/science/article/pii/S2211124720315333
  57. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
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    sciencedirect.com/science/article/pii/S2211124720314820
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    The Proinflammatory Cytokine IL-36γ Is a Global Discriminator of Harmless Microbes and Invasive Pathogens within Epithelial Tissues
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    sciencedirect.com/science/article/pii/S2211124720315047
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    Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis
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    sciencedirect.com/science/article/pii/S1934590920305427
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    Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs
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    sciencedirect.com/science/article/pii/S2211124720314649
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    The Master Regulator Protein BAZ2B Can Reprogram Human Hematopoietic Lineage-Committed Progenitors into a Multipotent State
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    sciencedirect.com/science/article/pii/S2211124720314637
  62. molecularbrain.biomedcentral.com molecularbrain.biomedcentral.com
    LRP4 LDLα repeats of astrocyte enhance dendrite arborization of the neuron
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    molecularbrain.biomedcentral.com/article/10.1186/s13041-020-00708-z
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    Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development
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    sciencedirect.com/science/article/pii/S0092867420314458
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration
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    ncbi.nlm.nih.gov/pmc/articles/PMC7685702/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC7707823/
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    A Cell-Based Assay Optimized for High-Content Cilia Imaging with Primary Rat Hippocampal Neurons
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    sciencedirect.com/science/article/pii/S2666166720301763
  67. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains
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    pubmed.ncbi.nlm.nih.gov/33238130/
  68. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    DNMT3A Haploinsufficiency Results in Behavioral Deficits and Global Epigenomic Dysregulation Shared across Neurodevelopmental Disorders
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    pubmed.ncbi.nlm.nih.gov/33238114/
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    Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand
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    sciencedirect.com/science/article/pii/S153458072030719X
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Role of Tet2 in modulating neuronal morphology and cognition in a mouse model of Alzheimer's disease
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15234
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor
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    ncbi.nlm.nih.gov/pmc/articles/PMC7688313/
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    High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies
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    sciencedirect.com/science/article/pii/S2352396420305077
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    Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens
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    sciencedirect.com/science/article/pii/S2211124720314492
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15060
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment
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    ncbi.nlm.nih.gov/pmc/articles/PMC7685708/
  76. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15169
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    TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson’s Disease
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    sciencedirect.com/science/article/pii/S2211124720314078
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7685705/
  79. www.embopress.org www.embopress.org
    Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA
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    embopress.org/doi/abs/10.15252/embj.2019103654
  80. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses
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    pubmed.ncbi.nlm.nih.gov/33275896/
  81. www.sciencedirect.com www.sciencedirect.com
    Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread
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    sciencedirect.com/science/article/pii/S221112472031398X
  82. Nov 2020
  83. www.sciencedirect.com www.sciencedirect.com
    Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies
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    sciencedirect.com/science/article/pii/S193131282030620X
  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel circular RNA 2960 contributes to secondary damage of spinal cord injury by sponging miRNA‐124
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    onlinelibrary.wiley.com/doi/10.1002/cne.25030
  85. www.sciencedirect.com www.sciencedirect.com
    Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17
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    sciencedirect.com/science/article/pii/S2211124720313541
  86. www.cell.com www.cell.com
    Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry
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    cell.com/neuron/abstract/S0896-6273(20)30401-3
  87. www.authorea.com www.authorea.com
    Natural Product Trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer
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    authorea.com/users/368637/articles/487712-natural-product-trienomycin-a-is-a-stat3-pathway-inhibitor-that-exhibits-potent-in-vitro-and-in-vivo-efficacy-against-pancreatic-cancer
  88. www.sciencedirect.com www.sciencedirect.com
    RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly
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    sciencedirect.com/science/article/pii/S2211124720313942
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homology-guided identification of a conserved motif linking the antiviral functions of IFITM3 to its oligomeric state
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    ncbi.nlm.nih.gov/pmc/articles/PMC7665892/
  90. www.medrxiv.org www.medrxiv.org
    http://medrxiv.org/cgi/content/short/2020.11.06.20227215
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    medrxiv.org/cgi/content/10.1101/2020.11.06.20227215
  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Missense mutations in CASK interfere with neurexin binding and neurexin‐induced oligomerization.
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