4,894 Matching Annotations
  1. Nov 2017
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    Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5
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    sciencedirect.com/science/article/pii/S1097276517304367
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    Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy
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    elifesciences.org/articles/25555
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    Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex
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    sciencedirect.com/science/article/pii/S1097276517304410
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    Densin-180 Controls the Trafficking and Signaling of L-Type Voltage-Gated Cav1.2 Ca2+ Channels at Excitatory Synapses
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    jneurosci.org/content/37/18/4679
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    Translation repression via modulation of the cytoplasmic poly(A)-binding protein in the inflammatory response
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    elifesciences.org/articles/27786
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    Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma
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    sciencedirect.com/science/article/pii/S1535610817302519
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    Body Temperature Cycles Control Rhythmic Alternative Splicing in Mammals
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    sciencedirect.com/science/article/pii/S1097276517304082
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    Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring
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    elifesciences.org/articles/25287
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    Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
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    elifesciences.org/articles/26030
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    Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions
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    sciencedirect.com/science/article/pii/S0896627317302970
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    Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining
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    ncbi.nlm.nih.gov/pmc/articles/PMC5468090/
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    Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development
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    sciencedirect.com/science/article/pii/S1534580717303957
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    The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling
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    elifesciences.org/articles/26362
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    Reduction of Ether-Type Glycerophospholipids, Plasmalogens, by NF-κB Signal Leading to Microglial Activation
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    jneurosci.org/content/37/15/4074
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    Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop
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    sciencedirect.com/science/article/pii/S1074761317301760
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    Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis
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    sciencedirect.com/science/article/pii/S0092867417304889
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    RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice
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    sciencedirect.com/science/article/pii/S0960982217304268
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    The Highly Dynamic Nature of ERdj5 Is Key to Efficient Elimination of Aberrant Protein Oligomers through ER-Associated Degradation
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    Untitled document
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    jneurosci.org/content/37/18/4679.long
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    SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency
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    sciencedirect.com/science/article/pii/S1931312817301579
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    Serotonergic Projections Govern Postnatal Neuroblast Migration
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    The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity
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    sciencedirect.com/science/article/pii/S0092867417304725
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    Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2
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    sciencedirect.com/science/article/pii/S1535610817301599
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    Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight
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    NPTX2 and cognitive dysfunction in Alzheimer’s Disease
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    elifesciences.org/content/6/e23798
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    Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target
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    Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult
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    elifesciences.org/content/6/e20725
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    A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis
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    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
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    elifesciences.org/content/6/e22871
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    Phospholipid localization implies microglial morphology and function via Cdc42 in vitro
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    onlinelibrary.wiley.com/doi/10.1002/glia.23123/full
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    Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis
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    Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD
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    elifesciences.org/content/6/e25068
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    Assembly of Excitatory Synapses in the Absence of Glutamatergic Neurotransmission
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    The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors
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    elifesciences.org/content/6/e24722
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    Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments
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    Multiplexed Engineering and Analysis of Combinatorial Enhancer Activity in Single Cells
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    Synthesis and Degradation of Adenosine 5′-Tetraphosphate by Nicotinamide and Nicotinate Phosphoribosyltransferases
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    A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors
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    ncbi.nlm.nih.gov/pmc/articles/PMC5338762/
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    SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation
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    elifesciences.org/content/6/e25158
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    Human Adaptation of Ebola Virus during the West African Outbreak
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    ncbi.nlm.nih.gov/pmc/articles/PMC5101188/
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    Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors
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    elifesciences.org/content/6/e22519
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    Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling
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    HDAC Inhibitor-Induced Mitotic Arrest Is Mediated by Eg5/KIF11 Acetylation
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    Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy
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    Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages
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    Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci
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    5′ End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding
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    Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions
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    Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling
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    A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination
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    Bassoon Controls Presynaptic Autophagy through Atg5
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    Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy
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    Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense
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    elifesciences.org/content/6/e21465
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    A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family
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    TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H 2 O 2
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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-017-0367-5
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    miR-219 Cooperates with miR-338 in Myelination and Promotes Myelin Repair in the CNS
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    sciencedirect.com/science/article/pii/S1534580717301223
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions
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    pmc.ncbi.nlm.nih.gov/articles/PMC5092050/
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    Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106
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    elifesciences.org/content/6/e19032
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    Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling
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    elifesciences.org/content/6/e20444
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Inhibitory Effect of α/β-Hydrolase Domain-Containing 6 (ABHD6) on the Surface Targeting of GluA2- and GluA3-Containing AMPA Receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC5333494/
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    GRASP1 Regulates Synaptic Plasticity and Learning through Endosomal Recycling of AMPA Receptors
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    Interferons Induce Expression of SAMHD1 in Monocytes through Down-regulation of miR-181a and miR-30a
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    Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit
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    Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator
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    elifesciences.org/articles/23063
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    One reporter for in-cell activity profiling of majority of protein kinase oncogenes
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    ncbi.nlm.nih.gov/pmc/articles/PMC5310841/
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    The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 α-enhancer activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC5308899/
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    A Neural Circuit for Auditory Dominance over Visual Perception
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    Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination
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    ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation
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    RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions
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    Ligand and Target Discovery by Fragment-Based Screening in Human Cells
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    Replication Study: Melanoma genome sequencing reveals frequent PREX2 mutations
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    elifesciences.org/content/6/e21634
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two subunits of human ORC are dispensable for DNA replication and proliferation
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    ncbi.nlm.nih.gov/pmc/articles/PMC5245961/
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    Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity
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    EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus
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    ncbi.nlm.nih.gov/pmc/articles/PMC5224922/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rational design of aptazyme riboswitches for efficient control of gene expression in mammalian cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5130294/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC5127641/
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    Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
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    elifesciences.org/articles/19760
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC5111884/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of mTORC1 by lysosomal calcium and calmodulin
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    ncbi.nlm.nih.gov/pmc/articles/PMC5106211/
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    Human Adaptation of Ebola Virus during the West African Outbreak
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion
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    ncbi.nlm.nih.gov/pmc/articles/PMC5063586/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC5078604/
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    C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
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    Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation
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    sciencedirect.com/science/article/pii/S0092867416312296
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    Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor
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    Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
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  89. Nov 2016
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of mTORC1 by lysosomal calcium and calmodulin
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    ncbi.nlm.nih.gov/pmc/articles/PMC5106211/