879 Matching Annotations
  1. Aug 2022
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    trim-21 promotes proteasomal degradation of CED-1 for apoptotic cell clearance in C. elegans
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    1. scibot 26 Aug 2022
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      DOI: 10.7554/eLife.76436

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    ncbi.nlm.nih.gov/pmc/articles/PMC9388098/
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    A small RNA-guided PRC2 complex eliminates DNA as an extreme form of transposon silencing
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      DOI: 10.1016/j.celrep.2022.111263

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    sciencedirect.com/science/article/pii/S2211124722010816
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    In vivo nanoscopic landscape of neurexin ligands underlying anterograde synapse specification
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      DOI: 10.1016/j.neuron.2022.07.027

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    sciencedirect.com/science/article/pii/S0896627322007061
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    Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression
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    1. scibot 23 Aug 2022
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      DOI: 10.1016/j.molcel.2022.07.014

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    sciencedirect.com/science/article/pii/S1097276522007109
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    Tripartite Motif 38 Attenuates Cardiac Fibrosis after Myocardial Infarction by Suppressing TAK1 Activation via TAB2/3 Degradation
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    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.isci.2022.104780

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    sciencedirect.com/science/article/pii/S2589004222010525
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    Negative autoregulation mitigates collateral RNase activity of repeat-targeting CRISPR-Cas13d in mammalian cells
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    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111226

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    sciencedirect.com/science/article/pii/S2211124722010439
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    Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
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      DOI: 10.1016/j.celrep.2022.111201

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    sciencedirect.com/science/article/pii/S221112472201018X
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    The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis
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      DOI: 10.1016/j.cmet.2022.07.011

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    sciencedirect.com/science/article/pii/S1550413122003102
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    EZH2 T367 phosphorylation activates p38 signaling through lysine methylation to promote breast cancer progression
    1
    1. scibot 12 Aug 2022
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      DOI: 10.1016/j.isci.2022.104827

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    sciencedirect.com/science/article/pii/S2589004222010999
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    Humanized substitutions of Vmat1 in mice alter amygdala-dependent behaviors associated with the evolution of anxiety
    1
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    sciencedirect.com/science/article/pii/S2589004222010720
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    LGP2 is essential for zebrafish survival through dual regulation of IFN antiviral response
    1
    1. scibot 10 Aug 2022
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      DOI: 10.1016/j.isci.2022.104821

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    sciencedirect.com/science/article/pii/S2589004222010938
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optical Clearing and 3D Analysis Optimized for Mouse and Human Pancreata
    2
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      AB_1549585

      DOI: 10.21769/BioProtoc.4103

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      AB_1549585

      DOI: 10.21769/BioProtoc.4103

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    ncbi.nlm.nih.gov/pmc/articles/PMC8376577/
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    Cxcr4 and Ackr3 regulate allocation of caudal ganglionic eminence-derived interneurons to superficial cortical layers
    1
    1. scibot 06 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111157

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    sciencedirect.com/science/article/pii/S2211124722009664
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    A dRASSF-STRIPAK-Imd-JAK/STAT axis controls antiviral immune response in Drosophila
    1
    1. scibot 02 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111143

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    sciencedirect.com/science/article/pii/S2211124722009524
  16. Jul 2022
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167
    1
    1. scibot 31 Jul 2022
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      DOI: 10.3390/ijms23147847

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    ncbi.nlm.nih.gov/pmc/articles/PMC9319455/
  18. 52.53.155.43 52.53.155.43
    Splicing factor PRP-19 regulates mitochondrial stress response
    1
    1. scibot 27 Jul 2022
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      DOI: 10.1093/lifemeta/loac009

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    52.53.155.43/cd9588496615eb4861d790aa05dbbe7775db3bf3/loac009-html.html
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    GPCR kinases generate an APH1A phosphorylation barcode to regulate amyloid-β generation
    1
    1. scibot 27 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111110

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    sciencedirect.com/science/article/pii/S2211124722009160
  20. www.jneurosci.org www.jneurosci.org
    Direct Observation of Compartment-Specific Localization and Dynamics of Voltage-Gated Sodium Channels
    1
    1. scibot 14 Jul 2022
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      DOI: 10.1523/JNEUROSCI.0086-22.2022

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    jneurosci.org/content/42/28/5482
  21. link.springer.com link.springer.com
    The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice
    1
    1. scibot 14 Jul 2022
      RRID:AB_1

      DOI: 10.1186/s12915-022-01368-2

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    link.springer.com/article/10.1186/s12915-022-01368-2
  22. www.sciencedirect.com www.sciencedirect.com
    Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5
    1
    1. scibot 13 Jul 2022
      RRID:AB_1549585

      DOI: 10.1016/j.celrep.2022.111067

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    sciencedirect.com/science/article/pii/S2211124722008658
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    A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand
    1
    1. scibot 13 Jul 2022
      RRID:AB_1549585

      DOI: 10.1016/j.celrep.2022.111039

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    sciencedirect.com/science/article/pii/S2211124722008336
  24. www.science.org www.science.org
    Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling
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    1. scibot 09 Jul 2022
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      DOI: 10.1126/sciadv.abn3868

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    science.org/doi/10.1126/sciadv.abn3868
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    LncNSPL facilitates influenza A viral immune escape by restricting TRIM25-mediated K63-linked RIG-I ubiquitination
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    1. scibot 08 Jul 2022
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      DOI: 10.1016/j.isci.2022.104607

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    sciencedirect.com/science/article/pii/S2589004222008793
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    Neural network organization for courtship-song feature detection in Drosophila
    1
    1. scibot 06 Jul 2022
      3724S

      DOI: 10.1016/j.cub.2022.06.019

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    sciencedirect.com/science/article/pii/S0960982222009782
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
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      DOI: 10.1158/0008-5472.CAN-20-4218

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    ncbi.nlm.nih.gov/pmc/articles/PMC9056178/
  28. Jun 2022
  29. 52.53.155.43 52.53.155.43
    cd-21-0646-html.html
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    1. scibot 30 Jun 2022
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      DOI: 10.1158/2159-8290.cd-21-0646

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      DOI: 10.1158/2159-8290.cd-21-0646

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      DOI: 10.1158/2159-8290.cd-21-0646

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    52.53.155.43/8eb6598be53599407b5cdbf0aa5958efcfba5063/cd-21-0646 (2)-html.html
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    An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma
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      DOI: 10.1016/j.molcel.2022.06.003

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    sciencedirect.com/science/article/pii/S1097276522005391
  31. www.nature.com www.nature.com
    BCL-2 isoform β promotes angiogenesis by TRiC-mediated upregulation of VEGF-A in lymphoma
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      DOI: 10.1038/s41388-022-02372-0

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    nature.com/articles/s41388-022-02372-0
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    Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1
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      DOI: 10.1016/j.celrep.2022.110971

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    sciencedirect.com/science/article/pii/S2211124722007574
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    A rice protein modulates endoplasmic reticulum homeostasis and coordinates with a transcription factor to initiate blast disease resistance
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      DOI: 10.1016/j.celrep.2022.110941

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    sciencedirect.com/science/article/pii/S2211124722007239
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    A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis
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      DOI: 10.1016/j.cmet.2022.05.009

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    sciencedirect.com/science/article/pii/S1550413122001917
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    Deubiquitinase OTUD3 regulates metabolism homeostasis in response to nutritional stresses
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    sciencedirect.com/science/article/pii/S1550413122001875
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    Active APPL1 sequestration by Plasmodium favors liver-stage development
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    sciencedirect.com/science/article/pii/S2211124722006611
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    Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis
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      DOI: 10.1016/j.celrep.2022.110851

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    sciencedirect.com/science/article/pii/S2211124722006246
  38. May 2022
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A bioactive phlebovirus-like envelope protein in a hookworm endogenous virus
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      DOI: 10.1126/sciadv.abj6894

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    ncbi.nlm.nih.gov/pmc/articles/PMC9094657/
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    All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain
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      DOI: 10.1016/j.crmeth.2022.100221

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    sciencedirect.com/science/article/pii/S2667237522000844
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
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      DOI: 10.7554/eLife.77696

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    ncbi.nlm.nih.gov/pmc/articles/PMC9113749/
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    Recurrent circadian circuitry regulates central brain activity to maintain sleep
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      DOI: 10.1016/j.neuron.2022.04.010

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    sciencedirect.com/science/article/pii/S089662732200349X
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    Walking strides direct rapid and flexible recruitment of visual circuits for course control in Drosophila
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    Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs
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    Generation of a CRF1-Cre transgenic rat and the role of central amygdala CRF1 cells in nociception and anxiety-like behavior
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    Non-apoptotic activation of Drosophila caspase-2/9 modulates JNK signaling, the tumor microenvironment, and growth of wound-like tumors
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    Rapid and efficient degradation of endogenous proteins in vivo identifies stage-specific roles of RNA Pol II pausing in mammalian development
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    Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C
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    The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma
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    Targeting HNRNPM inhibits cancer stemness and enhances antitumor immunity in Wnt-activated hepatocellular carcinoma
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    Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-dependent Manner
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    Deficiency of Mesencephalic Astrocyte-derived Neurotrophic Factor Affects Neurogenesis in Mouse Brain
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    DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding
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    PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II
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    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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    Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production
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    Coordinated repression of pro-differentiation genes via P-bodies and transcription maintains Drosophila intestinal stem cell identity
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    A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function
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    MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal
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    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
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    Tyrosine Phosphorylation of DEPTOR Functions as a Molecular Switch to Activate mTOR Signaling
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    Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation
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    A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes
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    Interactions between the Ig-Superfamily Proteins DIP-α and Dpr6/10 Regulate Assembly of Neural Circuits
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    The Transcription Factor Tox2 Drives T Follicular Helper Cell Development via Regulating Chromatin Accessibility
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      Rabbit monoclonal antibody anti-HA

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    Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication
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    Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons
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      DOI: 10.1016/j.neuron.2019.05.043

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  174. onlinelibrary.wiley.com onlinelibrary.wiley.com
    EphA2‐to‐YAP Pathway Drives Gastric Cancer Growth and Therapy Resistance
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      anti‐HA tag

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  175. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Functional analysis of novel RUNX2 mutations identified in patients with Cleidocranial dysplasia
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      HA‐Tag

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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_1549585

      DOI: 10.1016/j.celrep.2018.11.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6314484/
  177. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP+
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      DOI: 10.1111/jnc.14683

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  178. www.sciencedirect.com www.sciencedirect.com
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  180. www.sciencedirect.com www.sciencedirect.com
    Divergent Connectivity of Homologous Command-like Neurons Mediates Segment-Specific Touch Responses in Drosophila
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      DOI: 10.1016/j.neuron.2017.10.030

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  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  183. www.sciencedirect.com www.sciencedirect.com
    Nucleo-cytoplasmic Partitioning of ARF Proteins Controls Auxin Responses in Arabidopsis thaliana
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  184. www.sciencedirect.com www.sciencedirect.com
    Enteric glia regulate lymphocyte activation via autophagy-mediated MHC-II expression
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  185. www.sciencedirect.com www.sciencedirect.com
    Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
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  187. www.sciencedirect.com www.sciencedirect.com
    Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila
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  189. www.sciencedirect.com www.sciencedirect.com
    The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression
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  190. www.cell.com www.cell.com
    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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  191. Jun 2021
  192. www.sciencedirect.com www.sciencedirect.com
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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      RRID:AB_1549585

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    sciencedirect.com/science/article/pii/S2211124721006628
  193. www.sciencedirect.com www.sciencedirect.com
    Ca2+/calmodulin kinase II–dependent regulation of βIV-spectrin modulates cardiac fibroblast gene expression, proliferation, and contractility
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    1. scibot 25 Jun 2021
      Cell Signaling 3724

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  194. www.sciencedirect.com www.sciencedirect.com
    Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1
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    1. scibot 19 Jun 2021
      RRID:AB_1549585

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    sciencedirect.com/science/article/pii/S1550413121002709
  195. www.sciencedirect.com www.sciencedirect.com
    TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease
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      RRID:AB_1549585

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    CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells
    2
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      DOI: 10.1016/j.neuron.2021.05.007

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    sciencedirect.com/science/article/pii/S0896627321003330
  197. www.sciencedirect.com www.sciencedirect.com
    Generation of locus-specific degradable tag knock-ins in mouse and human cell lines
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      RRID:AB_1549585

      DOI: 10.1016/j.xpro.2021.100575

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    sciencedirect.com/science/article/pii/S2666166721002823
  198. www.sciencedirect.com www.sciencedirect.com
    Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
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      RRID:AB_1549585

      DOI: 10.1016/j.molcel.2021.05.005

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    sciencedirect.com/science/article/pii/S1097276521003622
  199. May 2021
  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of coordinated muscular relaxation in Drosophila larvae by a pattern-regulating intersegmental circuit
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      RRID:AB_1549585

      DOI: 10.1038/s41467-021-23273-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC8134441/
  201. www.sciencedirect.com www.sciencedirect.com
    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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    sciencedirect.com/science/article/pii/S1074761321001898
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    The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding
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  203. www.sciencedirect.com www.sciencedirect.com
    Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment
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      RRID:AB_1549585

      DOI: 10.1016/j.immuni.2021.04.024

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  204. www.sciencedirect.com www.sciencedirect.com
    A protocol for rapid degradation of endogenous transcription factors in mammalian cells and identification of direct regulatory targets
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    sciencedirect.com/science/article/pii/S2666166721002379
  205. www.sciencedirect.com www.sciencedirect.com
    Viral tegument proteins restrict cGAS-DNA phase separation to mediate immune evasion
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    sciencedirect.com/science/article/pii/S1097276521003592
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    SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
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      DOI: 10.1016/j.molcel.2021.04.002

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    Pro- and anti-apoptotic fate decisions induced by di- and trimeric synthetic cytokine receptors
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      DOI: 10.1016/j.isci.2021.102471

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    Chromatin structure-dependent histone incorporation revealed by a genome-wide deposition assay
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      DOI: 10.7554/eLife.66290

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