638 Matching Annotations
  1. Jul 2023
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    The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2
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    sciencedirect.com/science/article/pii/S2211124723007350
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    Blocking an epitope of misfolded SOD1 ameliorates disease phenotype in a model of amyotrophic lateral sclerosis
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    52.53.155.43/2945eba83e58c4a88c16c49d9e3b61762240780a/awad222-html.html
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    Bacterial effector restricts liquid-liquid phase separation of ZPR1 to antagonize host UPRER
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    sciencedirect.com/science/article/pii/S2211124723007118
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    Homotypic SCOTIN assemblies form ER-endosome membrane contacts and regulate endosome dynamics
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    embopress.org/doi/full/10.15252/embr.202256538
  6. Jun 2023
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    Circadian clocks are modulated by compartmentalized oscillating translation
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    sciencedirect.com/science/article/pii/S0092867423005998
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    Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage
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    science.org/doi/10.1126/sciadv.adf6600
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    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
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    sciencedirect.com/science/article/pii/S1934590923002114
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    Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage
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    ncbi.nlm.nih.gov/pmc/articles/PMC10266735/
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    Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation
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    Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility
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    Prolactin regulates testicular gene expression and cell cycle processes predominantly via JAK2/STAT5 pathway in male rat
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    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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    The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB
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  16. May 2023
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    DNA Methylation-Mediated Mfn2 Gene Regulation in the Brain: A Role in Brain Trauma-Induced Mitochondrial Dysfunction and Memory Deficits
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    link.springer.com/article/10.1007/s10571-023-01358-0
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    MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells
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    sciencedirect.com/science/article/pii/S2589004223007332
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    FEBS Press
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    Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway
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    eIF3 mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content
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    embopress.org/doi/10.15252/embj.2022112362
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    A network of small RNAs regulates sporulation initiation in Clostridioides difficile
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    embopress.org/doi/10.15252/embj.2022112858
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    Poly(ADP-ribose) polymerase family member 14 promotes... : Neural Regeneration Research
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154507/
  24. journals.physiology.org journals.physiology.org
    Neogenin pathway positively regulates fibronectin production by glomerular mesangial cells
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    journals.physiology.org/doi/full/10.1152/ajpcell.00359.2021
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    Neogenin pathway positively regulates fibronectin production by glomerular mesangial cells
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    Inward rectifying Kir4.1 channels regulate oligodendrocyte precursor cell differentiation and CNS myelination in vivo
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    sciencedirect.com/science/article/pii/S0304394023002379
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    GM1 Oligosaccharide Efficacy in Parkinson’s Disease: Protection against MPTP
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    mdpi.com/2227-9059/11/5/1305
  28. Apr 2023
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    Nucleation and Dissolution Mechanism Underlying ALS/FTLD-linked FUS Condensates
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    Reduced histone gene copy number disrupts Drosophila Polycomb function
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    biorxiv.org/content/10.1101/2023.03.28.534544v1
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    ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion
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    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
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    Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
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  34. Mar 2023
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    Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation
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    Triap1 upregulation promotes escape from mitotic-slippage-induced G1 arrest
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Green Fluorescent Polyamines to Analyze ATP13A2 and ATP13A3 Activity in the Mammalian Polyamine Transport System
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    ncbi.nlm.nih.gov/pmc/articles/PMC9953717/
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    PPT1 Regulation Of HSP90α Depalmitoylation Participates In The Pathogenesis Of Hyperandrogenism
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  39. Feb 2023
  40. academic.oup.com academic.oup.com
    Non-coding mutations in a thyroid hormone receptor gene that impair cone photoreceptor function
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    Genetic Val66Met BDNF Variant Increases Hyperphagia on Fat-rich Diets in Mice
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    Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC9935493/
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    Hyaluronan-Induced CD44-iASPP Interaction Affects Fibroblast Migration and Survival
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    mdpi.com/2072-6694/15/4/1082
  44. 52.53.155.43 52.53.155.43
    Bradykinin 2 Receptors Contribute to the Exaggerated Exercise Pressor Reflex in a Rat Model of Simulated Peripheral Artery Disease
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    An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation
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  46. Jan 2023
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    Elevated PAF1-RAD52 axis confers chemoresistance to human cancers
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    Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation
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    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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    Phenolic glycolipid-1 of Mycobacterium leprae is involved in human Schwann cell line ST8814 neurotoxic phenotype
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    SSRN-id4201001-html.html
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    A central role for regulated protein stability in the control of TFE3 and MITF by nutrients
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    DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma
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  54. Dec 2022
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    SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice
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    Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer
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    Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells
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    NMDA receptor hypofunction underlies deficits in parvalbumin interneurons and social behavior in neuroligin 3 R451C knockin mice
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  59. Nov 2022
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanisms governing target search and binding dynamics of hypoxia-inducible factors
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    Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella
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    Combinatorial prophylactic effect of phlorotannins with photobiomodulation against tracheal stenosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9664362/
  63. www.science.org www.science.org
    An orally active, small-molecule TNF inhibitor that disrupts the homotrimerization interface improves inflammatory arthritis in mice
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    P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection
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  65. Oct 2022
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    Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice
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    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
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    The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling
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  69. Sep 2022
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic Profile Variations along the Differentiation of Human-Induced Pluripotent Stem Cells to Dopaminergic Neurons
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    DNA-PKcs promotes fork reversal and chemoresistance
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    Virological features and pathogenicity of SARS-CoV-2 Omicron BA.2
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    Target protein localization and its impact on PROTAC-mediated degradation
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  74. Aug 2022
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    N1-methylpseudouridine found within COVID-19 mRNA vaccines produces faithful protein products
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    De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
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    The endoplasmic reticulum membrane complex promotes proteostasis of GABAA receptors
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    The intrinsic and extrinsic effects of TET proteins during gastrulation
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  79. Jul 2022
  80. link.springer.com link.springer.com
    Infarct-preconditioning exosomes of umbilical cord mesenchymal stem cells promoted vascular remodeling and neurological recovery after stroke in rats
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    The E3 ligase Thin controls homeostatic plasticity through neurotransmitter release repression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9299833/
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    Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC9296133/
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    Potassium channel Kir4.1 regulates oligodendrocyte differentiation via intracellular pH regulation
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    onlinelibrary.wiley.com/doi/10.1002/glia.24240
  84. Jun 2022
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    An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma
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    Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2
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    A function for Ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission
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    Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication
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    A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression
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    Interspecies commensal interactions have nonlinear impacts on host immunity
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    Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine
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    miR-182-5p Regulates Nogo-A Expression and Promotes Neurite Outgrowth of Hippocampal Neurons In Vitro
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    ncbi.nlm.nih.gov/pmc/articles/PMC9146179/
  93. May 2022
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    DDX41 is required for cGAS-STING activation against DNA virus infection
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    Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo
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  96. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glutamate–aspartate transporter 1 attenuates oxygen–glucose deprivation-induced injury by promoting glutamate metabolism in primary cortical neurons
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    onlinelibrary.wiley.com/doi/10.1002/jcp.30768
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    Intracellular infection and immune system cues rewire adipocytes to acquire immune function
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  98. Apr 2022
  99. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Novel mechanosensory role for acid sensing ion channel subtype 1a in evoking the exercise pressor reflex in rats with heart failure
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP282923
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    Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells
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    Centrosome-dependent microtubule modifications set the conditions for axon formation
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    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
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  103. Nov 2021
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    Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
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