1,316 Matching Annotations
  1. Nov 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway
    1
    1. scibot 03 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111571

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    sciencedirect.com/science/article/pii/S2211124722014322
  3. Oct 2022
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    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
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      DOI: 10.1016/j.cmet.2022.09.021

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    sciencedirect.com/science/article/pii/S1550413122004119
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    A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases
    1
    1. scibot 14 Oct 2022
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      DOI: 10.1016/j.chom.2022.09.012

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    sciencedirect.com/science/article/pii/S1931312822004681
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    Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy
    1
    1. scibot 13 Oct 2022
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    sciencedirect.com/science/article/pii/S2211124722012955
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    Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation
    1
    1. scibot 09 Oct 2022
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      DOI: 10.1016/j.molcel.2022.09.018

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    sciencedirect.com/science/article/pii/S1097276522009078
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    Yeast Mediator facilitates transcription initiation at most promoters via a Tail-independent mechanism
    1
    1. scibot 09 Oct 2022
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      DOI: 10.1016/j.molcel.2022.09.016

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    sciencedirect.com/science/article/pii/S1097276522009054
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    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
    1
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    sciencedirect.com/science/article/pii/S221112472201275X
  10. www.nature.com www.nature.com
    Regulation of KDM5C stability and enhancer reprogramming in breast cancer
    1
    1. scibot 05 Oct 2022
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      DOI: 10.1038/s41419-022-05296-5

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    nature.com/articles/s41419-022-05296-5
  11. Sep 2022
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolutionary analyses reveal immune cell receptor GPR84 as a conserved receptor for bacteria-derived molecules
    1
    1. scibot 28 Sep 2022
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      DOI: 10.1016/j.isci.2022.105087

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    ncbi.nlm.nih.gov/pmc/articles/PMC9508565/
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    Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization
    1
    1. scibot 22 Sep 2022
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    sciencedirect.com/science/article/pii/S2211124722011937
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    Heterologous reporter expression in the planarian Schmidtea mediterranea through somatic mRNA transfection
    1
    1. scibot 21 Sep 2022
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    sciencedirect.com/science/article/pii/S2667237522001801
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    Developmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers
    1
    1. scibot 16 Sep 2022
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    sciencedirect.com/science/article/pii/S1097276522008085
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    Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages
    1
    1. scibot 16 Sep 2022
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    sciencedirect.com/science/article/pii/S1534580722005950
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    Scalable CRISPR-Cas9 chemical genetic screens in non-transformed human cells
    1
    1. scibot 15 Sep 2022
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      DOI: 10.1016/j.xpro.2022.101675

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    sciencedirect.com/science/article/pii/S266616672200555X
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    Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy
    1
    1. scibot 15 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111349

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    sciencedirect.com/science/article/pii/S2211124722011779
  19. Aug 2022
  20. www.sciencedirect.com www.sciencedirect.com
    CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair
    1
    1. scibot 31 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111297

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    sciencedirect.com/science/article/pii/S2211124722011172
  21. journals.plos.org journals.plos.org
    Wnt5a–Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions
    1
    1. scibot 31 Aug 2022
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      DOI: 10.1371/journal.pbio.3001759

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    journals.plos.org/plosbiology/article
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    Tumor targeted 4-1BB agonist antibody-albumin fusions with high-affinity to FcRn induce anti-tumor immunity without toxicity
    1
    1. scibot 30 Aug 2022
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      DOI: 10.1016/j.isci.2022.104958

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    sciencedirect.com/science/article/pii/S2589004222012305
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    A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing
    1
    1. scibot 27 Aug 2022
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      DOI: 10.1016/j.molcel.2022.08.003

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    sciencedirect.com/science/article/pii/S1097276522007560
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    Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein
    1
    1. scibot 23 Aug 2022
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      DOI: 10.1016/j.chom.2022.07.016

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    sciencedirect.com/science/article/pii/S1931312822003626
  25. www.sciencedirect.com www.sciencedirect.com
    The redox cycling of STAT2 maintains innate immune homeostasis
    1
    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111215

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    sciencedirect.com/science/article/pii/S2211124722010324
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    STK25 inhibits PKA signaling by phosphorylating PRKAR1A
    1
    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111203

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    sciencedirect.com/science/article/pii/S2211124722010208
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCL10 mutations define distinct dependencies guiding precision therapy for DLBCL
    1
    1. scibot 11 Aug 2022
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      DOI: 10.1158/2159-8290.CD-21-1566

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    ncbi.nlm.nih.gov/pmc/articles/PMC9357155/
  28. www.sciencedirect.com www.sciencedirect.com
    Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity
    1
    1. scibot 10 Aug 2022
      RRID:AB_2922909

      DOI: 10.1016/j.celrep.2022.111167

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    sciencedirect.com/science/article/pii/S2211124722009809
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
    1
    1. scibot 04 Aug 2022
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      DOI: 10.1111/bph.15377

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    ncbi.nlm.nih.gov/pmc/articles/PMC9328656/
  30. elifesciences.org elifesciences.org
    A neural progenitor mitotic wave is required for asynchronous axon outgrowth and morphology
    1
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      DOI: 10.7554/eLife.75746

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    elifesciences.org/articles/75746
  31. Jul 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
    1
    1. scibot 30 Jul 2022
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      DOI: 10.1016/j.molcel.2022.06.035

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    sciencedirect.com/science/article/pii/S1097276522006530
  33. www.sciencedirect.com www.sciencedirect.com
    Mycobacterium abscessus HelR interacts with RNA polymerase to confer intrinsic rifamycin resistance
    1
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      DOI: 10.1016/j.molcel.2022.06.034

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    sciencedirect.com/science/article/pii/S1097276522006529
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation
    1
    1. scibot 27 Jul 2022
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      DOI: 10.1111/febs.16375

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    ncbi.nlm.nih.gov/pmc/articles/PMC9309721/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFIA determines the cis-effect of genetic variation on Ucp1 expression in murine thermogenic adipocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9304612/
  36. www.sciencedirect.com www.sciencedirect.com
    FAM69C, a kinase critical for synaptic function and memory, is defective in neurodegenerative dementia
    1
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    sciencedirect.com/science/article/pii/S2211124722009032
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    Calcium sparks enhance the tissue fluidity within epithelial layers and promote apical extrusion of transformed cells
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      DOI: 10.1016/j.celrep.2022.111078

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    sciencedirect.com/science/article/pii/S2211124722008762
  38. www.sciencedirect.com www.sciencedirect.com
    RPA1 controls chromatin architecture and maintains lipid metabolic homeostasis
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      DOI: 10.1016/j.celrep.2022.111071

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    sciencedirect.com/science/article/pii/S2211124722008695
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    Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover
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      DOI: 10.1016/j.devcel.2022.06.011

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    sciencedirect.com/science/article/pii/S1534580722004518
  40. www.science.org www.science.org
    Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling
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      DOI: 10.1126/sciadv.abn3868

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    science.org/doi/10.1126/sciadv.abn3868
  41. Jun 2022
  42. 52.53.155.43 52.53.155.43
    can-21-3868-html.html
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      DOI: 10.1158/0008-5472.can-21-3868

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    52.53.155.43/28b9d48499bd7231fb316ef079ea180b1643cc31/can-21-3868 (1)-html.html
  43. 52.53.155.43 52.53.155.43
    SLC46A3 is a lysosomal proton-coupled steroid conjugate and bile acid transporter involved in transport of active catabolites of T-DM1
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      DOI: 10.1093/pnasnexus/pgac063

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    52.53.155.43/1e2eeb06c036dc03866e7ff6dabeb7bf48a513c3/pgac063-html.html
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    Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2
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      DOI: 10.1016/j.str.2022.06.001

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    sciencedirect.com/science/article/pii/S0969212622002325
  45. www.jneurosci.org www.jneurosci.org
    Dynein is required for Rab7-dependent endosome maturation, retrograde dendritic transport, and degradation
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      DOI: 10.1523/JNEUROSCI.2530-21.2022

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    jneurosci.org/content/42/22/4415
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    Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses
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      DOI: 10.1016/j.chembiol.2022.05.009

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    A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination
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    Functional Assessment of Calcium-Sensing Receptor Variants Confirms Familial Hypocalciuric Hypercalcaemia
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  88. Mar 2022
  89. www.sciencedirect.com www.sciencedirect.com
    Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes
    1
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      DOI: 10.1016/j.molcel.2022.03.005

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  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms
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      DOI: 10.1111/jnc.14666

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  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silencing of Ago-2 Interacting Protein SERBP1 Relieves KCC2 Repression by miR-92 in Neurons
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  93. www.sciencedirect.com www.sciencedirect.com
    The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m6A recognition
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    PTENα regulates endocytosis and modulates olfactory function
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Division of Labor between YAP and TAZ in Non–Small Cell Lung Cancer
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  96. www.sciencedirect.com www.sciencedirect.com
    Delicate regulation of IL-1β-mediated inflammation by cyclophilin A
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    Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake
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    Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses
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    Crosstalk between ERK and MRTF-A signaling regulates TGFβ1-induced epithelial-mesenchymal transition
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The NDNF-like factor Nord is a Hedgehog-induced extracellular BMP modulator that regulates Drosophila wing patterning and growth
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maelstrom functions in the production of Siwi-piRISC capable of regulating transposons in Bombyx germ cells
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    Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
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    Transcription factor Hhex negatively regulates osteoclast differentiation by controlling cyclin-dependent kinase inhibitors
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    Resurfaced ZIKV EDIII nanoparticle immunogens elicit neutralizing and protective responses in vivo
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    SARM1 IS A MULTI-FUNCTIONAL NAD(P)ASE WITH PROMINENT BASE EXCHANGE ACTIVITY, ALL REGULATED BY MULTIPLE PHYSIOLOGICALLY-RELEVANT NAD METABOLITES
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  106. Feb 2022
  107. www.sciencedirect.com www.sciencedirect.com
    SENP2 suppresses browning of white adipose tissues by de-conjugating SUMO from C/EBPβ
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    Thyroid hormone regulates glutamine metabolism and anaplerotic fluxes by inducing mitochondrial glutamate aminotransferase GPT2
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    The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation
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    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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    Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Pyruvate Kinase M2 phosphorylation reverses aggressive cancer phenotypes
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      DOI: 10.1158/0008-5472.CAN-20-4190

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    TMEM106A inhibits enveloped virus release from cell surface
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    Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease
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    Paternal transmission of the Wolbachia CidB toxin underlies cytoplasmic incompatibility
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    Bivalent-histone-marked immediate-early gene regulation is vital for VEGF-responsive angiogenesis
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    PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP dependent lipid uptake and fatty acid synthesis pathways
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    Enhanced immunoprecipitation techniques for the identification of RNA binding protein partners: IGF2BP1 interactions in mammary epithelial cells
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility
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  121. Jan 2022
  122. www.sciencedirect.com www.sciencedirect.com
    Proteomic screen reveals diverse protein transport between connected neurons in the visual system
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    RNA N6-methyladenosine modification promotes auxin biosynthesis required for male meiosis in rice
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    Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1
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      DOI: 10.7554/eLife.72823

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    Acetylation-dependent regulation of BRAF oncogenic function
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  127. www.science.org www.science.org
    Redox-dependent internalization of the purinergic P2Y6 receptor limits colitis progression
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    Super-Resolution Imaging of the Filtration Barrier Suggests a Role for Podocin R229Q in Genetic Predisposition to Glomerular Disease
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    Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub
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    DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing
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    S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity
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    FKBP51 Affects TNF-Related Apoptosis Inducing Ligand Response in Melanoma
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    Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia
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    Connected neurons in multiple neocortical areas, comprising parallel circuits, encode essential information for visual shape learning
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    Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A
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    Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis
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